Philip S. Portoghese - Publications, H-index & Citations

Philip S. Portoghese

University of Minnesota Twin Cities

69H指数

508论文数

1.8W被引数

收录论文 88

发表时间

Peripherally mediated opioid combination therapy in mouse and pig

JOURNAL OF PAIN

IF4

2025-02-01

PREAI

Peterson, C. D.; Larson, C. M.; Bruce, D. J.; Clements, B. M.; Pflepsen, K. R.; Akgun, E.; Kitto, K. F.; Lunzer, M. M.; Fairbanks, C. A.; Portoghese, P. S.; Wilcox, G. L.

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

IF3.7

2024-12-31

PREAI

Tran, Linh T.; Freeman, Katie T.; Lunzer, Mary M.; Portoghese, Philip S.; Haskell-Luevano, Carrie

In Memory of Professor Hualiang Jiang 纪念蒋华良教授

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-08-30

PREAI

Ding, Ke; Wang, Shaomeng; Georg, Gunda; Portoghese, Philip; Lindsley, Craig

The bivalent ligand, MMG22, reduces neuropathic pain after nerve injury without the side effects of traditional opioids

PAIN

IF5.5

2020-04-27

OAAI

Speltz, Rebecca; Lunzer, Mary M.; Shueb, Sarah S.; Akgun, Eyup; Reed, Rachelle; Kalyuzhny, Alex; Portoghese, Philip S.; Simone, Donald A.

Stereochemistry and innate immune recognition: (+)-norbinaltorphimine targets myeloid differentiation protein 2 and inhibits toll-like receptor 4 signaling

FASEB JOURNAL

IF4.2

2019-06-04

OAAI

Zhang, Xiaozheng; Peng, Yinghua; Grace, Peter M.; Metcalf, Matthew D.; Kwilasz, Andrew J.; Wang, Yibo; Zhang, Tianshu; Wu, Siru; Selfridge, Brandon R.; Portoghese, Philip S.; Rice, Kenner C.; Watkins, Linda R.; Hutchinson, Mark R.; Wang, Xiaohui

Bivalent ligand MCC22 potently attenuates nociception in a murine model of sickle cell disease

PAIN

IF5.5

2018-03-22

OAAI

Cataldo, Giuseppe; Lunzer, Mary M.; Olson, Julie K.; Akgun, Eyup; Belcher, John D.; Vercellotti, Gregory M.; Portoghese, Philip S.; Simone, Donald A.

Bivalent ligand that activates mu opioid receptor and antagonizes mGluR5 receptor reduces neuropathic pain in mice

PAIN

IF5.5

2017-09-01

OAAI

Peterson, Cristina D.; Kitto, Kelley F.; Akgun, Eyup; Lunzer, Mary M.; Riedl, Maureen S.; Vulchanova, Lucy; Wilcox, George L.; Portoghese, Philip S.; Fairbanks, Carolyn A.

Heteromer Induction: An Approach to Unique Pharmacology?

ACS CHEMICAL NEUROSCIENCE

IF3.9

2017-01-31

PREAI

Portoghese, Philip S.; Akguen, Eyup; Lunzer, Mary M.

Modulation of musculoskeletal hyperalgesia by brown adipose tissue activity in mice

PAIN

IF5.5

2016-07-19

OAAI

Goudie-DeAngelis, Elizabeth M.; Abdelhamid, Ramy E.; Nunez, Myra G.; Kissel, Casey L.; Kovacs, Katalin J.; Portoghese, Philip S.; Larson, Alice A.

Inhibition of Inflammatory and Neuropathic Pain by Targeting a Mu Opioid Receptor/Chemokine Receptor5 Heteromer (MOR-CCR5)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2015-10-20

OAAI

Akguen, Eyup; Javed, Muhammad I.; Lunzer, Mary M.; Powers, Michael D.; Sham, Yuk Y.; Watanabe, Yoshikazu; Portoghese, Philip S.

Targeting putative mu opioid/metabotropic glutamate receptor-5 heteromers produces potent antinociception in a chronic murine bone cancer model

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2014-11-01

OAAI

Smeester, Branden A.; Lunzer, Mary M.; Akgun, Eyup; Beitz, Alvin J.; Portoghese, Philip S.

Putative Kappa Opioid Heteromers As Targets for Developing Analgesics Free of Adverse Effects

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2014-07-18

OAAI

Le Naour, Morgan; Lunzer, Mary M.; Powers, Michael D.; Kalyuzhny, Alexander E.; Benneyworth, Michael A.; Thomas, Mark J.; Portoghese, Philip S.

Bivalent Ligands That Target μ Opioid (MOP) and Cannabinoid1 (CB1) Receptors Are Potent Analgesics Devoid of Tolerance

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2013-06-20

OAAI

Le Naour, Morgan; Akguen, Eyup; Yelddrala, Ajay; Lunzer, Mary M.; Powers, Mike D.; Kalyuzhny, Alexander E.; Portoghese, Philip S.

An Immunocytochemical-Derived Correlate for Evaluating the Bridging of Heteromeric Mu-Delta Opioid Protomers by Bivalent Ligands

ACS CHEMICAL BIOLOGY

IF3.8

2013-05-17

OAAI

Yekkirala, Ajay S.; Kalyuzhny, Alexander E.; Portoghese, Philip S.

Application of the message-address concept to the docking of naltrexone and selective naltrexone-derived opioid antagonists into opioid receptor models

NEUROCHEMICAL RESEARCH

IF3.8

2013-03-21

PREAI

Metzger, TG; Paterlini, MG; Portoghese, PS; Ferguson, DM

Reduced Antinociception of Opioids in Rats and Mice by Vaccination with Immunogens Containing Oxycodone and Hydrocodone Haptens

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2013-01-15

OAAI

Pravetoni, Marco; Le Naour, Morgan; Tucker, Ashli M.; Harmon, Theresa M.; Hawley, Tara M.; Portoghese, Philip S.; Pentel, Paul R.

Clinically Employed Opioid Analgesics Produce Antinociception via μ-δ Opioid Receptor Heteromers in Rhesus Monkeys

ACS CHEMICAL NEUROSCIENCE

IF3.9

2012-07-20

OAAI

Yekkirala, Ajay S.; Banks, Matthew L.; Lunzer, Mary M.; Negus, Stevens S.; Rice, Kenner C.; Portoghese, Philip S.

The δ Opioid Receptor Agonist SNC80 Selectively Activates Heteromeric μ-δ Opioid Receptors

ACS CHEMICAL NEUROSCIENCE

IF3.9

2012-05-24

OAAI

Metcalf, Matthew D.; Yekkirala, Ajay S.; Powers, Michael D.; Kitto, Kelley F.; Fairbanks, Carolyn A.; Wilcox, George L.; Portoghese, Philip S.

Molecular Basis for Binding and Subtype Selectivity of 1,4-Benzodiazepine Antagonist Ligands of the Cholecystokinin Receptor

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2012-05-01

OAAI

Cawston, Erin E.; Lam, Polo C. H.; Harikumar, Kaleeckal G.; Dong, Maoqing; Ball, Alicja M.; Augustine, Mary Lou; Akguen, Eyup; Portoghese, Philip S.; Orry, Andrew; Abagyan, Ruben; Sexton, Patrick M.; Miller, Laurence J.

An Oxycodone Conjugate Vaccine Elicits Drug-Specific Antibodies that Reduce Oxycodone Distribution to Brain and Hot-Plate Analgesia

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2012-04-01

OAAI

Pravetoni, M.; Le Naour, M.; Harmon, T. M.; Tucker, A. M.; Portoghese, P. S.; Pentel, P. R.

研究方向