Dominik Feuerbach - Publications, H-index & Citations

Dominik Feuerbach

Novartis

33H指数

146论文数

3.1K被引数

收录论文 42

发表时间

Genetic models of cleavage-reduced and soluble TREM2 reveal distinct effects on myelination and microglia function in the cuprizone model 裂解减少和可溶性TREM2的遗传模型揭示了cuprezone模型对髓鞘形成和小胶质细胞功能的不同影响

JOURNAL OF NEUROINFLAMMATION

IF10.1

2023-02-08

OAAI

Beckmann, Nicolau; Neuhaus, Anna; Zurbruegg, Stefan; Volkmer, Pia; Patino, Claudia; Joller, Stefanie; Feuerbach, Dominik; Doelemeyer, Arno; Schweizer, Tatjana; Rudin, Stefan; Neumann, Ulf; Berth, Ramon; Frieauff, Wilfried; Gasparini, Fabrizio; Shimshek, Derya R.

Sustained Trem2 stabilization accelerates microglia heterogeneity and Af3 pathology in a mouse model of Alzheimer's disease 在阿尔茨海默氏病小鼠模型中，持续的Trem2稳定可加速小胶质细胞异质性和Af3病理学

CELL REPORTS

IF6.9

2022-05-01

OAAI

Dhandapani, Rahul; Neri, Marilisa; Bernhard, Mario; Brzak, Irena; Schweizer, Tatjana; Rudin, Stefan; Joller, Stefanie; Berth, Ramon; Kernen, Jasmin; Neuhaus, Anna; Waldt, Annick; Cuttat, Rachel; Naumann, Ulrike; Keller, Caroline Gubser; Roma, Guglielmo; Feuerbach, Dominik; Shimshek, Derya R.; Neumann, Ulf; Gasparini, Fabrizio; Galimberti, Ivan

Selectivity of ( ± )-citalopram at nicotinic acetylcholine receptors and different inhibitory mechanisms between habenular α3β4*and α9α10 subtypes

NEUROCHEMISTRY INTERNATIONAL

IF4

2019-12-01

OAAI

Arias, Hugo R.; Jin, Xiao-Tao; Gallino, Sofia; Peng, Can; Feuerbach, Dominik; Garcia-Colunga, Jesus; Belen Elgoyhen, Ana; Drenan, Ryan M.; Ortells, Marcelo O.

Alkaloids Purified from Aristotelia chilensis Inhibit the Human α3β4 Nicotinic Acetylcholine Receptor with Higher Potencies Compared with the Human α3β4 and α7 Subtypes

JOURNAL OF NATURAL PRODUCTS

IF3.6

2019-07-05

PREAI

Arias, Hugo R.; Ortells, Marcelo O.; Feuerbach, Dominik; Burgos, Viviana; Paz, Cristian

The Discovery of LML134, a Histamine H3 Receptor Inverse Agonist for the Clinical Treatment of Excessive Sleep Disorders 组胺H3受体反向激动剂LML134用于临床治疗过度睡眠障碍的发现

CHEMMEDCHEM

IF3.4

2019-05-21

PREAI

Troxler, Thomas; Feuerbach, Dominik; Zhang, Xuechun; Yang, Charles R.; Lagu, Bharat; Perrone, Mark; Wang, Tie-Lin; Briner, Karin; Bock, Mark G.; Auberson, Yves P.

Tricyclic antidepressants inhibit hippocampal α7*and α9α10 nicotinic acetylcholine receptors by different mechanisms

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IF2.8

2018-07-01

OAAI

Arias, Hugo R.; Vazquez-Gomez, Elizabeth; Hernandez-Abrego, Andy; Gallino, Sofia; Feuerbach, Dominik; Ortells, Marcelo O.; Belen Elgoyhen, Ana; Garcia-Colunga, Jesus

Drimane Sesquiterpenoids Noncompetitively Inhibit Human α4β2 Nicotinic Acetylcholine Receptors with Higher Potency Compared to Human α3β4 and α7 Subtypes

JOURNAL OF NATURAL PRODUCTS

IF3.6

2018-04-10

PREAI

Arias, Hugo R.; Feuerbach, Dominik; Schmidt, Bernd; Heydenreich, Matthias; Paz, Cristian; Ortells, Marcelo O.

Selectivity of coronaridine congeners at nicotinic acetylcholine receptors and inhibitory activity on mouse medial habenula

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IF2.8

2017-11-01

OAAI

Arias, Hugo R.; Jin, Xiaotao; Feuerbach, Dominik; Drenan, Ryan M.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

IF3.9

2016-11-01

OAAI

Barch, Deanna M.; Marder, Stephen R.; Harms, Michael P.; Jarskog, L. Fredrik; Buchanan, Robert W.; Cronenwett, Will; Chen, Li-Shiun; Weiss, Markus; Maguire, Ralph P.; Pezous, Nicole; Feuerbach, Dominik; Lopez-Lopez, Cristina; Johns, Donald R.; Behrje, Rhett B.; Gomez-Mancilla, Baltazar

Bupropion and its photoreactive analog (±)-SADU-3-72 interact with luminal and non-luminal sites at human α4β2 nicotinic acetylcholine receptors

NEUROCHEMISTRY INTERNATIONAL

IF4

2016-11-01

OAAI

Arias, Hugo R.; Feuerbach, Dominik; Ortells, Marcelo O.

Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IF2.8

2016-07-01

OAAI

Arias, Hugo R.; Ravazzini, Federica; Targowska-Duda, Katarzyna M.; Kaczor, Agnieszka A.; Feuerbach, Dominik; Boffi, Juan C.; Draczkowski, Piotr; Montag, Dirk; Brown, Brandon M.; Elgoyhen, Ana Belen; Jozwiak, Krzysztof; Puia, Giulia

A Placebo-Controlled Trial of AQW051 in Patients With Moderate to Severe Levodopa-Induced Dyskinesia

MOVEMENT DISORDERS

IF7.6

2016-03-15

OAAI

Trenkwalder, Claudia; Berg, Daniela; Rascol, Olivier; Eggert, Karla; Ceballos-Baumann, Andres; Corvol, Jean-Christophe; Storch, Alexander; Zhang, Lin; Azulay, Jean-Philippe; Broussolle, Emmanuel; Defebvre, Luc; Geny, Christian; Gostkowski, Michal; Stocchi, Fabrizio; Tranchant, Christine; Derkinderen, Pascal; Durif, Franck; Espay, Alberto J.; Feigin, Andrew; Houeto, Jean-Luc; Schwarz, Johannes; Di Paolo, Therese; Feuerbach, Dominik; Hockey, Hans-Ulrich; Jaeger, Judith; Jakab, Annamaria; Johns, Donald; Linazasoro, Gurutz; Maruff, Paul; Rozenberg, Izabela; Sovago, Judit; Weiss, Markus; Gomez-Mancilla, Baltazar

Coronaridine congeners inhibit human α3β4 nicotinic acetylcholine receptors by interacting with luminal and non-luminal sites

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IF2.8

2015-08-01

PREAI

Arias, Hugo R.; Targowska-Duda, Katarzyna M.; Feuerbach, Dominik; Jozwiak, Krzysztof

The antidepressant-like activity of nicotine, but not of 3-furan-2-yl-N-p-tolyl-acrylamide, is regulated by the nicotinic receptor β4 subunit

NEUROCHEMISTRY INTERNATIONAL

IF4

2015-08-01

PREAI

Arias, Hugo R.; Targowska-Duda, Katarzyna M.; Feuerbach, Dominik; Jozwiak, Krzysztof

Functional and structural interaction of (-)-lobeline with human α4β2 and α4β4 nicotinic acetylcholine receptor subtypes

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IF2.8

2015-07-01

OAAI

Arias, Hugo R.; Feuerbach, Dominik; Ortells, Marcelo

AQW051, a novel, potent and selective α7 nicotinic ACh receptor partial agonist: pharmacological characterization and phase I evaluation

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2015-01-12

OAAI

Feuerbach, Dominik; Pezous, Nicole; Weiss, Markus; Shakeri-Nejad, Kasra; Lingenhoehl, Kurt; Hoyer, Daniel; Hurth, Konstanze; Bilbe, Graeme; Pryce, Christopher R.; McAllister, Kevin; Chaperon, Frederique; Kucher, Klaus; Johns, Donald; Blaettler, Thomas; Lopez Lopez, Cristina

From Ergolines to Indoles: Improved Inhibitors of the Human H3 Receptor for the Treatment of Narcolepsy 从麦角林到吲哚: 用于治疗发作性睡病的人类H3受体的改良抑制剂

CHEMMEDCHEM

IF3.4

2014-11-12

PREAI

Auberson, Yves P.; Troxler, Thomas; Zhang, Xuechun; Yang, Charles R.; Feuerbach, Dominik; Liu, Yu-Chih; Lagu, Bharat; Perrone, Mark; Lei, Lijun; Shen, Xiaoxia; Zhang, Dushan; Wang, Chunxiu; Wang, Tie-Lin; Briner, Karin; Bock, Mark G.

AQW051, a novel and selective nicotinic acetylcholine receptor α7 partial agonist, reduces L-Dopa-induced dyskinesias and extends the duration of L-Dopa effects in parkinsonian monkeys AQW051是一种新型的选择性烟碱乙酰胆碱受体 α7部分激动剂，可减轻L-多巴引起的运动障碍，并延长L-多巴对帕金森病猴子的作用时间

PARKINSONISM & RELATED DISORDERS

IF3.4

2014-11-01

PREAI

Di Paolo, Therese; Gregoire, Laurent; Feuerbach, Dominik; Elbast, Walid; Weiss, Markus; Gomez-Mancilla, Baltazar

Bupropion-induced inhibition of α7 nicotinic acetylcholine receptors expressed in heterologous cells and neurons from dorsal raphe nucleus and hippocampus

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2014-10-01

PREAI

Vazquez-Gomez, Elizabeth; Arias, Hugo R.; Feuerbach, Dominik; Miranda-Morales, Marcela; Mihailescu, Stefan; Targowska-Duda, Katarzyna M.; Jozwiak, Krzysztof; Garcia-Colunga, Jesus

Ergoline-Derived Inverse Agonists of the Human H3 Receptor for the Treatment of Narcolepsy

CHEMMEDCHEM

IF3.4

2014-05-21

PREAI

Auberson, Yves P.; Troxler, Thomas; Zhang, Xuechun; Yang, Charles R.; Fendt, Markus; Feuerbach, Dominik; Liu, Yu-Chih; Lagu, Bharat; Lerchner, Andreas; Perrone, Mark; Lei, Lijun; Zhang, Chao; Wang, Chunxiu; Wang, Tie-Lin; Bock, Mark G.

研究方向