Zhongning Guo - Publications, H-index & Citations

Zhongning Guo

sichuan university

3H指数

12论文数

20被引数

收录论文 5

发表时间

Discovery and Pharmacological Evaluation of Potent and Highly Selective PARP1 Inhibitors 发现和药理学评价高活性、高选择性的PARP1抑制剂

Journal of Medicinal Chemistry

IF6.8

2025-06-18

PREAI

Tao Guo; Yongting Yuan; Ziyan Ma; Yurong Zou; Minghai Tang; Zhongning Guo; Zhiyuan Fu; Weichen Bo; Peng Wang; Shuai Liu; Hao Huang; Junfeng Hu; Zhuang Yang; Tao Jia; Taijin Wang; Lijuan Chen

Predicting the Brain-To-Plasma Unbound Partition Coefficient of Compounds via Formula-Guided Network 通过公式引导网络预测化合物的大脑-血浆自由分配系数

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2025-05-09

PREAI

Zou, Yurong; Yuan, Haolun; Guo, Zhongning; Guo, Tao; Fu, Zhiyuan; Wang, Ruihan; Xu, Dingguo; Wang, Qiantao; Wang, Taijin

A structure-based framework for selective inhibitor design and optimization 基于结构的框架用于选择性抑制剂的研发与优化

COMMUNICATIONS BIOLOGY

IF5.1

2025-03-12

OAAI

Zou, Yurong; Guo, Tao; Fu, Zhiyuan; Guo, Zhongning; Bo, Weichen; Yan, Dengjie; Wang, Qiantao; Zeng, Jun; Xu, Dingguo; Wang, Taijin; Chen, Lijuan

Design, Synthesis, and Pharmacodynamic Evaluation of Highly Selective PARP1 Inhibitors with Brain Penetrance 设计、合成及具有脑渗透性的高选择性PARP1抑制剂的药效学评价

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2025-01-10

PREAI

Guo, Tao; Yuan, Yongting; Zou, Yurong; Guo, Zhongning; Tang, Minghai; Ma, Ziyan; Fu, Zhiyuan; Bo, Weichen; Wang, Peng; Bai, Peng; Wang, Taijin; Jia, Tao; Yang, Jianhong; Chen, Lijuan

Design, Synthesis, and Biological Evaluation of 5-Amino-4-fluoro-1H-benzo[d]imidazole-6-carboxamide Derivatives as Novel and Potential MEK/RAF Complex Inhibitors Based on the Clamp Strategy

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-08-21

PREAI

Wang, Peng; Yuan, Yongting; Yang, Tao; Zou, Yurong; Tang, Minghai; Ma, Ziyan; Bo, Weichen; Qin, Songhui; Chen, Yong; Guo, Tao; Guo, Zhongning; Yang, Jianhong; Xiang, Mingli; Chen, Lijuan

研究方向