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M

Minghai Tang

sichuan university

36H指数
197论文数
4.0K被引数
收录论文 107
发表时间
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System-level metabolic and enzyme engineering enables high-titer gastrodin biosynthesis in yeast系统水平的代谢与酶工程使酵母中高滴度天麻素的生物合成成为可能
errBioresource Technology
IF9
err2026-05-04
err0
PREAI
errXiaowen Wan; Donghao Li; Minghai Tang; Zewen Liu; Jiayu Pan; Hongbin Yu; Jinliang Yang; Huayi Liu
err分享
err收藏
Structure-Based Design and Synthesis of KX-01 Analogs as Potent Antitumor Agents Targeting the Tubulin Colchicine Binding Site基于结构的KX-01类似物的设计合成及其作为靶向微管秋水仙碱结合位点的强效抗肿瘤剂
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-04-11
err0
PREAI
errChufeng Zhang; Yilin Wang; Chenke Gao; Maoru Sun; Minghai Tang; Fang Wang; Hongxiu Chen; Shuai Zhang; Li Liu; Qingqing Li; Xue Cui; Xiuying Hu; Zhuang Yang; Jianhong Yang; Yong Li
err分享
err收藏
Hyperglutaminolysis drives senescence and aging through arginine-mTORC1 axis activation高谷氨酰胺分解通过精氨酸-mTORC1轴的激活驱动衰老和老化。
errSignal Transduction and Targeted Therapy
IF52.7
err2026-02-19
err0
errOAAI
errHonghan Chen; Ning Huang; Weitong Xu; Yu Yang; Fangfang Wang; Hui Gong; Jiao Zhou; Haoran Tai; Tingting Zhao; Jian Zhang; Ying Li; Ge Liang; Minghai Tang; Jie Li; Ming Yang; Jin Liu; Xiaoli Huang; Hengyi Xiao
err分享
err收藏
Rational Design of Novel pyrazolo[4; 3-c]quinoline Derivatives as Potent; Selective; and Orally Bioavailable ATM Inhibitors with Promising In Vivo Efficacy新型吡唑并[4;3-c]喹啉衍生物的理性设计，作为强效、选择性且口服生物利用度高的ATM抑制剂，具有有前景的体内疗效。
errJournal of Medicinal Chemistry
IF6.8
err2026-02-11
err0
PREAI
errTao Yang; Tao Guo; Yongting Yuan; Minghai Tang; Xue Cui; Min Zhao; Meng Qin; Zhuang Yang
err分享
err收藏
Prevention of cancer initiation by augmenting MHC-I antigen presentation via EZH2 inhibition通过抑制EZH2增强MHC-I抗原呈递来预防癌症起始
errOncogene
IF7.3
err2025-11-24
err0
PREAI
errWei Ding; Zihan Ding; Qinghong Zeng; Yan Qiu; Christopher R. Donnelly; Yuqi Wu; Yuchen Jiang; Qi Han; Hao Xu; Hao Cui; Xiangfei Liu; Xin Chen; Sixin Jiang; Mei Huang; Dan Pan; Dan Yang; Li Li; Lihong Yao; Minghai Tang; Jing Li; Taiwen Li; Xiaoping Xu; Qianming Chen; Hang Zhao; Longyu Li; Lu Jiang; Xiaobo Luo
err分享
err收藏
Covalent modification of Keap1 Cys489 by NU6300 activates Nrf2 signaling and suppresses NLRP3 inflammasome-mediated pyroptosisNU6300对Keap1 Cys489的共价修饰激活了Nrf2信号通路，并抑制了NLRP3炎性小体介导的焦亡。
errJournal of Pharmaceutical Analysis
IF8.9
err2025-09-30
err0
errOAAI
errXueqin Jiang; Hongyu Zheng; Xinlu Zhang; Minghai Tang; Jing Peng; Xiaoying Cai; Kaiyue Su; Ruijia Zhang; Neng Ye; Lei Lin; Rupei Ma; Caiyun Shen; Wenshuang Wu; Haoyu Ye
err分享
err收藏
Discovery and Pharmacological Evaluation of Potent and Highly Selective PARP1 Inhibitors发现和药理学评价高活性、高选择性的PARP1抑制剂
errJournal of Medicinal Chemistry
IF6.8
err2025-06-18
err0
PREAI
errTao Guo; Yongting Yuan; Ziyan Ma; Yurong Zou; Minghai Tang; Zhongning Guo; Zhiyuan Fu; Weichen Bo; Peng Wang; Shuai Liu; Hao Huang; Junfeng Hu; Zhuang Yang; Tao Jia; Taijin Wang; Lijuan Chen
err分享
err收藏
CMD-OPT model enables the discovery of a potent and selective RIPK2 inhibitor as preclinical candidate for the treatment of acute liver injuryCMD-OPT模型能够发现一种强效且选择性的RIPK2抑制剂，作为治疗急性肝损伤的预临床试验候选药物。
errActa Pharmaceutica Sinica B
IF14.6
err2025-05-13
err0
errOAAI
errYong Chen; Xue Yuan; Wei Yan; Yurong Zou; Haoche Wei; Yuhan Wei; Minghai Tang; Yulian Chen; Ziyan Ma; Tao Yang; Kongjun Liu; Baojian Xiong; Xiuying Hu; Jianhong Yang; Lijuan Chen
err分享
err收藏
A rapid and sensitive LC-MS/MS method for the simultaneous determination of chlorfenapyr and its major metabolite tralopyril in human plasma: From method development, validation to clinical application一种快速且灵敏的LC-MS/MS方法，用于同时测定人血浆中chlorfenapyr及其主要代谢物tralopyril：从方法开发、验证到临床应用
errJOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
IF2.8
err2025-05-01
err0
PREAI
errTang, Shiyuan; Zhang, Shunjie; Du, Hongling; Yang, Xia; Yao, Qunmei; Peng, Aihua; Tang, Minghai
err分享
err收藏
An advanced deep learning approach for energy absorption prediction in porous metals across diverse strain rate scenarios一种用于预测多孔金属材料在不同应变率场景下能量吸收的先进深度学习方法
errCOMPUTATIONAL MATERIALS SCIENCE
IF3.3
err2025-05-01
err0
PREAI
errTang, Minghai; Wang, Lei; Song, Junyong
err分享
err收藏
Distribution, metabolism, and excretion of [14C] purinostat mesylate, a novel selective HDAC I/IIb inhibitor, in rats analyzed by high-performance liquid chromatography coupled with LTQ orbitrap mass spectrometry/ radioactivity monitoring[14C]嘌呤司他甲磺酸盐（一种新型选择性HDAC I/IIb抑制剂）在体内的分布、代谢和排泄研究，采用高效液相色谱法联用LTQ Orbitrap质谱仪/放射性检测进行分析。
errJOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
IF3.1
err2025-04-15
err0
PREAI
errMa, Ziyan; Tang, Minghai; Yang, Linyu
err分享
err收藏
Identification of a ligand-binding site on tubulin mediating the tubulin-RB3 interaction在微管蛋白上鉴定介导微管蛋白-RB3相互作用的配体结合位点
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2025-03-11
err0
errOAAI
errLi, Yong; Zhang, Chufeng; Tang, Dongmei; Wang, Tao; Yan, Wei; Yang, Linyu; Bai, Peng; Tang, Minghai; Pei, Heying; Chen, Lijuan; Chen, Qiang
err分享
err收藏
Identification of a 7H-pyrrolo[2,3-d]pyrimidin derivatives as selective type II c-Met/Axl inhibitors with potent antitumor efficacy鉴定7H-吡咯并[2,3-d]嘧啶衍生物作为选择性II型c-Met/Axl抑制剂的抗肿瘤活性强。
errBIOORGANIC CHEMISTRY
IF4.7
err2025-03-01
err0
PREAI
errQin, Songhui; Xie, Lixin; Tang, Minghai; Ni, Hengfan; Yang, Tao
err分享
err收藏
Design and Synthesis of Novel Deazapurine DNMT 1 Inhibitors with In Vivo Efficacy in DLBCL新型去氮嘌呤DNMT 1抑制剂的设计与合成及其在DLBCL中的体内疗效
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-03-01
err0
PREAI
errYang, Linyu; Yang, Tao; Wen, Yi; Tang, Minghai; Teng, Yaxin; Zhang, Wanhua; Zheng, Yunhua; Chen, Lijuan
err分享
err收藏
High energy absorption design of porous metals using deep learning基于深度学习的多孔金属高能量吸收设计
errINTERNATIONAL JOURNAL OF MECHANICAL SCIENCES
IF9.4
err2024-11-01
err3
PREAI
errTang, Minghai; Wang, Lei; Xin, Zhiqiang; Luo, Zikun
err分享
err收藏
Discovery of a Potent, Orally Active, and Long-Lasting P2X7 Receptor Antagonist as a Preclinical Candidate for Delaying the Progression of Chronic Kidney Disease
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-09-23
err0
PREAI
errZhang, Ruijia; Su, Kaiyue; Yang, Letian; Duan, Huaichuan; Tang, Lei; Tang, Minghai; Zhao, Min; Ye, Neng; Cai, Xiaoying; Jiang, Xueqin; Li, Na; Peng, Jing; Zhang, Xinlu; Tang, Lingkai; Qiu, Qiang; Chen, Lijuan; Wu, Wenshuang; Hu, Jianping; Ma, Liang; Ye, Haoyu
err分享
err收藏
Toxicokinetics, in vivo metabolic profiling and tissue distribution of chlorfenapyr in mice
errARCHIVES OF TOXICOLOGY
IF6.9
err2024-08-28
err1
PREAI
errZhang, Shunjie; Wang, Xin; Yang, Xia; Ma, Ziyang; Liu, Peng; Tang, Shiyuan; Zhao, Min; Chen, Haijun; Qiu, Qiang; Tang, Minghai; Peng, Aihua; Cao, Yu
err分享
err收藏
Discovery of Potent, Specific, and Orally Available NLRP3 Inflammasome Inhibitors Based on Pyridazine Scaffolds for the Treatment of Septic Shock and Peritonitis
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-08-22
err2
PREAI
errFu, Zhiyuan; Duan, Yangqin; Pei, Heying; Zou, Yurong; Tang, Minghai; Chen, Yong; Yang, Tao; Ma, Ziyan; Yan, Wei; Su, Kaiyue; Cai, Xiaoying; Guo, Tao; Teng, Yaxin; Jia, Tao; Chen, Lijuan
err分享
err收藏
Design, Synthesis, and Biological Evaluation of 5-Amino-4-fluoro-1H-benzo[d]imidazole-6-carboxamide Derivatives as Novel and Potential MEK/RAF Complex Inhibitors Based on the Clamp Strategy
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-08-21
err0
PREAI
errWang, Peng; Yuan, Yongting; Yang, Tao; Zou, Yurong; Tang, Minghai; Ma, Ziyan; Bo, Weichen; Qin, Songhui; Chen, Yong; Guo, Tao; Guo, Zhongning; Yang, Jianhong; Xiang, Mingli; Chen, Lijuan
err分享
err收藏
The EPRS-ATF4-COLI pathway axis is a potential target for anaplastic thyroid carcinoma therapy
errPHYTOMEDICINE
IF8.3
err2024-07-01
err2
PREAI
errMi, Li; Liu, Jiaye; Zhang, Yujie; Su, Anping; Tang, Minghai; Xing, Zhichao; He, Ting; Wei, Tao; Li, Zhihui; Wu, Wenshuang
err分享
err收藏

研究方向

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合作学者
合作期刊
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Wei Zheng
H 指数: 141 · 论文数: 2.5K
刘
刘艳 (Yan Liu)
H 指数: 118 · 论文数: 3.7K
Y
Yuquan Wei
H 指数: 111 · 论文数: 1.2K
杨
杨剑 (Jian Yang)
H 指数: 98 · 论文数: 689
钱
钱志勇 (Zhiyong Qian)
H 指数: 83 · 论文数: 500
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