未登录Engineering hemoglobin to enable homogenous PEGylation without modifying protein functionality
Cooper, Chris E.; Silkstone, Gary G. A.; Simons, Michelle; Gretton, Svetlana; Rajagopal, Badri S.; Allen-Baume, Victoria; Syrett, Natalie; Shaik, Thoufieq; Popa, Gina; Sheng, XiaoBo; Bird, Matthew; Choi, Ji-Won; Piano, Riccardo; Ronda, Luca; Bettati, Stefano; Paredi, Gianluca; Mozzarelli, Andrea; Reeder, Brandon J. .png)
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收藏Engineering tyrosine residues into hemoglobin enhances heme reduction, decreases oxidative stress and increases vascular retention of a hemoglobin based blood substitute将酪氨酸残基工程化为血红蛋白可增强血红素的减少，减少氧化应激并增加基于血红蛋白的血液替代品的血管保留Cooper, Chris E.; Silkstone, Gary G. A.; Simons, Michelle; Rajagopal, Badri; Syrett, Natalie; Shaik, Thoufieq; Gretton, Svetlana; Welbourn, Elizabeth; Bulow, Leif; Eriksson, Nelida Leiva; Ronda, Luca; Mozzarelli, Andrea; Eke, Andras; Mathe, Domokos; Reeder, Brandon J. 分享 收藏 Comparison of the oxidative reactivity of recombinant fetal and adult human hemoglobin: implications for the design of hemoglobin-based oxygen carriersSimons, Michelle; Gretton, Svetlana; Silkstone, Gary G. A.; Rajagopal, Badri S.; Allen-Baume, Victoria; Syrett, Natalie; Shaik, Thoufieq; Leiva-Eriksson, Nelida; Ronda, Luca; Mozzarelli, Andrea; Strader, Michael B.; Alayash, Abdu I.; Reeder, Brandon J.; Cooper, Chris E. 分享 收藏 
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