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Specific autoimmune infiltration of stem cell-derived beta cell grafts in type 1 diabetes patient-derived personalized immune mice but not in PBMC-humanized mice Zanetti, Giorgia; Mcheik, Soha; Danzl, Nichole; Traum, Daniel; Li, Hao Wei; Agashe, Vrushali; Wang, Hui; Winchester, Robert; Ding, Xiaolan; Fathi, Farshid; Bhatele, Sakshi; Wang, Ning; Egli, Dieter; Parent, Audrey; Sykes, Megan 分享 收藏
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An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury Fleischer, Sharon; Nash, Trevor R.; Tamargo, Manuel A.; Lock, Roberta I.; Venturini, Gabriela; Morsink, Margaretha; Graney, Pamela L.; Li, Vanessa; Lamberti, Morgan J.; Liberman, Martin; Kim, Youngbin; Tavakol, Daniel N.; Zhuang, Richard Z.; Whitehead, Jaron; Friedman, Richard A.; Soni, Rajesh K.; Seidman, Jonathan G.; Seidman, Christine E.; Geraldino-Pardilla, Laura; Winchester, Robert; Vunjak-Novakovic, Gordana 分享 收藏
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An Engineered Human Cardiac Tissue Model Reveals The Potential Contribution Of Systemic Lupus Erythematosus Autoantibodies To Myocardial Injury Nash, Trevor R.; Fleischer, Sharon; Tamargo, Manuel A.; Lock, Roberta I.; Morsink, Margaretha; Li, Vanessa; Lamberti, Morgan J.; Graney, Pamela L.; Liberman, Martin; Kim, Youngbin; Zhuang, Richard Z.; Whitehead, Jaron; Friedman, Richard A.; Soni, Rajesh K.; Geraldino-Pardilla, Laura; Winchester, Robert; Vunjak-Novakovic, Gordana 分享 收藏
Single-cell RNA sequencing reveals distinct T cell populations in immune-related adverse events of checkpoint inhibitors Bukhari, Shoiab; Henick, Brian S.; Winchester, Robert J.; Lerrer, Shalom; Adam, Kieran; Gartshteyn, Yevgeniya; Maniar, Rohan; Lin, Ziyan; Khodadadi-Jamayran, Alireza; Tsirigos, Aristotelis; Salvatore, Mary M.; Lagos, Galina G.; Reiner, Steven L.; Dallos, Matthew C.; Mathew, Matthen; Rizvi, NaiyerA.; Mor, Adam 分享 收藏
Upregulation of type 1 conventional dendritic cells implicates antigen cross-presentation in multisystem inflammatory syndrome Huang, Janice J.; Gaines, Samantha B.; Amezcua, Mateo L.; Lubell, Tamar R.; Dayan, Peter S.; Dale, Marissa; Boneparth, Alexis D.; Hicar, Mark D.; Winchester, Robert; Gorelik, Mark 分享 收藏
Role of the thymus in spontaneous development of a multi-organ autoimmune disease in human immune system mice Khosravi-Maharlooei, Mohsen; Li, HaoWei; Hoelzl, Markus; Zhao, Guiling; Ruiz, Amanda; Misra, Aditya; Li, Yang; Teteloshvili, Nato; Nauman, Grace; Danzl, Nichole; Ding, Xiaolan; Pinker, Elisha Y.; Obradovic, Aleksandar; Yang, Yong-Guang; Iuga, Alina; Creusot, Remi J.; Winchester, Robert; Sykes, Megan 分享 收藏
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Cross-reactive public TCR sequences undergo positive selection in the human thymic repertoire Khosravi-Maharlooei, Mohsen; Obradovic, Aleksandar; Misra, Aditya; Motwani, Keshav; Holz, Markus; Seay, Howard R.; DeWolf, Susan; Nauman, Grace; Danzl, Nichole; Li, Haowei; Ho, Siu-hong; Winchester, Robert; Shen, Yufeng; Brusko, Todd M.; Sykes, Megan 分享 收藏
Quantifying size and diversity of the human T cell alloresponse DeWolf, Susan; Grinshpun, Boris; Savage, Thomas; Lau, Sai Ping; Obradovic, Aleksandar; Shonts, Brittany; Yang, Suxiao; Morris, Heather; Zuber, Julien; Winchester, Robert; Sykes, Megan; Shen, Yufeng 分享 收藏
Hypercholesterolemia induces T cell expansion in humanized immune mice Proto, Jonathan D.; Doran, Amanda C.; Subramanian, Manikandan; Wang, Hui; Zhang, Mingyou; Sozen, Erdi; Rymond, Christina C.; Kuriakose, George; D'Agati, Vivette; Winchester, Robert; Sykes, Megan; Yang, Yong-Guang; Tabas, Ira 分享 收藏
Adipose Tissue Macrophages in Rheumatoid Arthritis: Prevalence, Disease-Related Indicators, and Associations With Cardiometabolic RiskFactors Giles, Jon T.; Ferrante, Antony W.; Broderick, Rachel; Zartoshti, Afshin; Rose, Janine; Downer, Kendall; Zhang, Hui-Zhu; Winchester, Robert J. 分享 收藏
HSC extrinsic sex-related and intrinsic autoimmune disease-related human B-cell variation is recapitulated in humanized mice Borsotti, Chiara; Danzl, Nichole M.; Nauman, Grace; Holzl, Markus A.; French, Clare; Chavez, Estefania; Khosravi-Maharlooei, Mohsen; Glauzy, Salome; Delmotte, Fabien R.; Meffre, Eric; Savage, David G.; Campbell, Sean R.; Goland, Robin; Greenberg, Ellen; Bi, Jing; Satwani, Prakash; Yang, Suxiao; Bathon, Joan; Winchester, Robert; Sykes, Megan 分享 收藏
Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney-Bone Marrow Transplantation to Induce Transplantation Tolerance Sprangers, B.; DeWolf, S.; Savage, T. M.; Morokata, T.; Obradovic, A.; LoCascio, S. A.; Shonts, B.; Zuber, J.; Lau, S. P.; Shah, R.; Morris, H.; Steshenko, V.; Zorn, E.; Preffer, F. I.; Olek, S.; Dombkowski, D. M.; Turka, L. A.; Colvin, R.; Winchester, R.; Kawai, T.; Sykes, M. 分享 收藏
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