James J. Manfredi - Publications, H-index & Citations

James J. Manfredi

newyork-presbyterian hospital

43H指数

176论文数

6.6K被引数

收录论文 59

发表时间

Mutant p53: evolving perspectives 突变p53：不断发展的观点

GENES & DEVELOPMENT

IF7.7

2026-01-01

PREAI

Efe, Gizem; Cunningham, Katherine; Rustgi, Anil K.; Prives, Carol; Manfredi, James J.; Sanchez-Rivera, Francisco J.

Mutant p53 regulates a distinct gene set by a mode of genome occupancy that is shared with wild type

EMBO REPORTS

IF6.2

2025-01-28

OAAI

Rahme, Ramy; Resnick-Silverman, Lois; Anguiano, Vincent; Campbell, Moray J.; Fenaux, Pierre; Manfredi, James J.

p53-R172H mutation confers gain-of-function properties and promotes metastasis in squamous cell carcinoma

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Efe, Gizem; Cunningham, Katherine; de Bobadilla, Raul Navaridas Fernandez; Dunbar, Karen J.; Sugiura, Kensuke; Nishiwaki, Noriyuki; Carcamo, Saul; Resnick-Silverman, Lois; Hasson, Dan; Klein-Szanto, Andres J.; Taylor, Alison M.; Manfredi, James J.; Prives, Carol; Rustgi, Anil K.

p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression

CANCER DISCOVERY

IF33.3

2023-09-07

PREAI

Efe, Gizem; Dunbar, Karen J.; Sugiura, Kensuke; Cunningham, Katherine; Carcamo, Saul; Karaiskos, Spyros; Tang, Qiaosi; Cruz-Acuna, Ricardo; Resnick-Silverman, Lois; Peura, Jessica; Lu, Chao; Hasson, Dan; Klein-Szanto, Andres J.; Taylor, Alison M.; Manfredi, James J.; Prives, Carol; Rustgi, Anil K.

TP53 Alterations in Myelodysplastic Syndromes and Acute Myeloid Leukemia

BIOMEDICINES

IF3.9

2023-04-11

OAAI

Rahme, Ramy; Braun, Thorsten; Manfredi, James J.; Fenaux, Pierre

The role of mutant p53-mediated mechanisms in modulating the tumor microenvironment and promoting lung metastasis

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Efe, Gizem; Cunningham, Katherine M.; Tang, Qiaosi; Sugiura, Kensuke; Dunbar, Karen; Suzuki, Kensuke; Resnick-Silverman, Lois; Taylor, Alison M.; Manfredi, James J.; Prives, Carol L.; Rustgi, Anil K.

Specific regulation of BACH1 by the hotspot mutant p53R175H reveals a distinct gain-of-function mechanism

NATURE CANCER

IF28.5

2023-03-27

OAAI

Su, Zhenyi; Kon, Ning; Yi, Jingjie; Zhao, Haiqing; Zhang, Wanwei; Tang, Qiaosi; Li, Huan; Kobayashi, Hiroki; Li, Zhiming; Duan, Shoufu; Liu, Yanqing; Olive, Kenneth P. P.; Zhang, Zhiguo; Honig, Barry; Manfredi, James J. J.; Rustgi, Anil K. K.; Gu, Wei

Mdm2 is required for inhibition of Cdk2 activity by p21, thereby contributing to p53-dependent cell cycle arrest

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Giono, Luciana E.; Manfredi, James J.

In vivo RNA-seq and ChIP-seq analyses show an obligatory role for the C terminus of p53 in conferring tissue-specific radiation sensitivity

CELL REPORTS

IF6.9

2023-03-01

OAAI

Resnick-Silverman, Lois; Zhou, Royce; Campbell, Moray J.; Leibling, Ian; Parsons, Ramon; Manfredi, James J.

Mutant p53-mediated CSF1/CSF1R signaling promotes tumor invasion and lung metastasis in esophageal squamous cell carcinoma

CANCER RESEARCH

IF16.6

2023-01-15

PREAI

Efe, Gizem; Tang, Qiaosi; Cunningham, Katherine M.; Sugiura, Kensuke; Dunbar, Karen; Regunath, Kausik; Suzuki, Kensuke; Klein-Szanto, Andres J.; Resnick-Silverman, Lois; Manfredi, James J.; Prives, Carol L.; Rustgi, Anil K.

The TP53 Database: transition from the International Agency for Research on Cancer to the US National Cancer Institute

CELL DEATH AND DIFFERENTIATION

IF15.4

2022-03-29

OAAI

de Andrade, Kelvin Cesar; Lee, Elaine E.; Tookmanian, Elise M.; Kesserwan, Chimene A.; Manfredi, James J.; Hatton, Jessica N.; Loukissas, Jennifer K.; Zavadil, Jiri; Zhou, Lei; Olivier, Magali; Frone, Megan N.; Shahzada, Owais; Longabaugh, William J. R.; Kratz, Christian P.; Malkin, David; Hainaut, Pierre; Savage, Sharon A.

p53 Frameshift Mutations Couple Loss-of-Function with Unique Neomorphic Activities

MOLECULAR CANCER RESEARCH

IF4.7

2021-05-27

OAAI

Tong, David R.; Zhou, Wen; Katz, Chen; Regunath, Kausik; Venkatesh, Divya; Ihuegbu, Chinyere; Manfredi, James J.; Laptenko, Oleg; Prives, Carol

Mdm2 and MdmX: Partners in p53 Destruction Mdm2和MdmX: p53破坏的伙伴

CANCER RESEARCH

IF16.6

2021-04-01

OAAI

Manfredi, James J.

Robust p53 Stabilization Is Dispensable for Its Activation and Tumor Suppressor Function

CANCER RESEARCH

IF16.6

2021-02-15

OAAI

Kon, Ning; Churchill, Michael; Li, Huan; Mukherjee, Siddhartha; Manfredi, James J.; Gu, Wei

Distinct mechanisms control genome recognition by p53 at its target genes linked to different cell fates 不同的机制控制p53在其与不同细胞命运相关的靶基因上的基因组识别

NATURE COMMUNICATIONS

IF15.7

2021-01-20

OAAI

Farkas, Marina; Hashimoto, Hideharu; Bi, Yingtao; Davuluri, Ramana V.; Resnick-Silverman, Lois; Manfredi, James J.; Debler, Erik W.; McMahon, Steven B.

p53 defies convention again: a p53 mutant that has lost tumor suppression but still can kill

EMBO JOURNAL

IF8.3

2019-09-25

OAAI

Manfredi, James J.

Inactivation of Wild-Type p53 by Asparagine Endopeptidase in Glioblastoma: An Opportunity to Target the Undruggable

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE

IF7.2

2019-08-10

OAAI

Manfredi, James J.