未登录 分享 收藏
. Integrative spatiotemporal proteomic and metabolomic characterization of immune infiltration following intracranial injection of oncolytic immunotherapy in glioblastoma patients 胶质瘤患者颅内注射溶瘤免疫疗法后免疫浸润的整合时空蛋白质组学和代谢组学表征 Gantchev, Jennifer; Baquer, Gerard; Zheng, Peter; D'souza, Alicia; Ling, Alexander; Regan, Michael; Teamlab, G. B. M.; Deshpande, Atul; White, Forest; Yu, Kenny; Chiocca, E. Antonio; Couturier, Charles; Agar, Nathalie 分享 收藏
BIWT: a bioinformatics walkthrough for embedding spatial multiomics in agent-based models for virtual cells Bergman, Daniel R.; Johnson, Jeanette A. I.; Naji, Marwa; Booth, Max; da Rocha, Heber Lima; Deshpande, Atul; Sidiropoulos, Dimitrios N.; Lopez-Vidal, Tamara; Heiland, Randy; Kagohara, Luciane T.; Anders, Robert A.; Zheng, Lei; Jaffee, Elizabeth M.; Stein-O'brien, Genevieve; Macklin, Paul; Fertig, Elana J. 分享 收藏
CD137 agonism enhances anti-PD1 induced activation of expanded CD8+ T cell clones in a neoadjuvant pancreatic cancer clinical trial CD137激动作用增强了新辅助性胰腺癌临床试验中抗PD-1诱导的扩增CD8+ T细胞克隆的激活。 Montagne, Janelle M.; Mitchell, Jacob T.; Tandurella, Joseph A.; Christenson, Eric S.; Danilova, Ludmila, V; Deshpande, Atul; Loth, Melanie; Sidiropoulos, Dimitrios N.; Davis-Marcisak, Emily; Bergman, Daniel R.; Zhu, Qingfeng; Wang, Hao; Kagohara, Luciane T.; Engle, Logan L.; Green, Benjamin F.; Favorov, Alexander, V; Ho, Won Jin; Lim, Su Jin; Zhang, Rui; Li, Pan; Gai, Jessica; Mo, Guanglan; Mitchell, Sarah; Wang, Rulin; Vaghasia, Ajay; Hou, Wenpin; Xu, Yao; Zimmerman, Jacquelyn W.; Elisseeff, Jennifer H.; Yegnasubramanian, Srinivasan; Anders, Robert A.; Jaffee, Elizabeth M.; Zheng, Lei; Fertig, Elana J. 分享 收藏
分享 收藏
Spatial transcriptomics reveals heterogeneity of epithelial and stromal compartments in healthy and tumor pancreas Elhossiny, Ahmed M.; Okoye, Jude; Williams, Imade; Zhang, Yaqing; Watkoske, Hannah; Deshpande, Atul; Fertig, Elana; Rao, Arvind; Carpenter, Eileen S.; Frankel, Timothy L.; di Magliano, Marina Pasca 分享 收藏
Computational methods and biomarker discovery strategies for spatial proteomics: a review in immuno-oncology 空间蛋白质组学的计算方法和生物标志物发现策略: 免疫肿瘤学综述 Mi, Haoyang; Sivagnanam, Shamilene; Ho, Won Jin; Zhang, Shuming; Bergman, Daniel; Deshpande, Atul; Baras, Alexander S.; Jaffee, Elizabeth M.; Coussens, Lisa M.; Fertig, Elana J.; Popel, Aleksander S. 分享 收藏
Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells Grasset, Eloise M.; Deshpande, Atul; Lee, Jae W.; Cho, Yeonju; Shin, Sarah M.; Coyne, Erin M.; Hernandez, Alexei; Yuan, Xuan; Zhang, Zhehao; Cimino-Mathews, Ashley; Ewald, Andrew J.; Ho, Won Jin 分享 收藏
PanIN and CAF transitions in pancreatic carcinogenesis revealed with spatial data integration Bell, Alexander T. F.; Mitchell, Jacob T.; Kiemen, Ashley L.; Lyman, Melissa; Fujikura, Kohei; Lee, Jae W.; Coyne, Erin; Shin, Sarah M.; Nagaraj, Sushma; Deshpande, Atul; Wu, Pei-Hsun; Sidiropoulos, Dimitrios N.; Erbe, Rossin; Stern, Jacob; Chan, Rena; Williams, Stephen; Chell, James M.; Ciotti, Lauren; Zimmerman, Jacquelyn W.; Wirtz, Denis; Ho, Won Jin; Zaidi, Neeha; Thompson, Elizabeth; Jaffee, Elizabeth M.; Wood, Laura D.; Fertig, Elana J.; Kagohara, Luciane T. 分享 收藏
Integration of Clinical Trial Spatial Multiomics Analysis and Virtual Clinical Trials Enables Immunotherapy Response Prediction and Biomarker Discovery Zhang, Shuming; Deshpande, Atul; Verma, Babita K.; Wang, Hanwen; Mi, Haoyang; Yuan, Long; Ho, Won Jin; Jaffee, Elizabeth M.; Zhu, Qingfeng; Anders, Robert A.; Yarchoan, Mark; Kagohara, Luciane T.; Fertig, Elana J.; Popel, Aleksander S. 分享 收藏
Machine learning integrating spatial omics uncovers humoral immunity patterns in intratumoral tertiary lymphoid structures in pancreatic cancer pathologic responders Sidiropoulos, Dimitrios N.; Shin, Sarah M.; Girgis, Alexander; Shu, Daniel H.; Montagne, Janelle; Deshpande, Atul; Johnson, Jeanette A.; Dequiedt, Lucie; Jacobs, Victoria; Ogurtsova, Aleksandra; Mo, Guanglan; Yuan, Xuan; Stein-O'Brien, Genevieve; Yarchoan, Mark; Zhu, Qingfeng; Kiemen, Ashley; Jaffee, Elizabeth M.; Zheng, Lei; Ho, Won Jin; Anders, Robert; Fertig, Elana J.; Kagohara, Luciane T. 分享 收藏
Integrating spatial multi-omics data with spatial quantitative pharmacology (spQSP) model to simulate human neoadjuvant immunotherapy clinical trial of hepatocellular carcinoma Zhang, Shuming; Deshpande, Atul; Verma, Babita K.; Wang, Hanwen; Mi, Haoyang; Yuan, Long; Ho, Won Jin; Jaffee, Elizabeth M.; Zhu, Qingfeng; Anders, Robert A.; Yarchoan, Mark; Kagohara, Luciane T.; Fertig, Elana J.; Popel, Aleksander S. 分享 收藏
A differential ligand- receptor network inference method to identify alterations in communication between myeloid cells and CD8 T cells in response to PancVAX neo-epitope peptide vaccine, anti-CTLA-4 and anti-PD-1 antibodies in a murine model of pancreatic ductal adenocarcinoma Mitchell, Jacob T.; Deshpande, Atul; Huff, Amanda L.; Cherry, Chris; Nagaraj, Sushma; Krishnan, Kavita; Lvovs, Dmitrijs; Elisseeff, Jennifer H.; Jaffee, Elizabeth M.; Zaidi, Neeha; Fertig, Elana J. 分享 收藏
Spatial proteomics and transcriptomics reveal early immune cell organization in human pancreatic intraepithelial neoplasia Lyman, Melissa R.; Mitchell, Jacob T.; Kagohara, Luciane T.; Huff, Amanda L.; Haldar, Daniel; Shin, Sarah; Guinn, Samantha; Barrett, Benjamin; Longway, Gabriella; Hernandez, Alexei; Coyne, Erin; Yuan, Xuan; Andaloori, Lalitya; Lai, Jiaying; Liu, YunZhou; Karchin, Rachel; Gupta, Anuj; Kiemen, Ashley; Forjaz, Andre; Wirtz, Denis; Wu, Pei-Hsun; Deshpande, Atul; Armstrong, Todd; Azad, Nilofer S.; Thompson, Elizabeth; Anders, Robert; Ho, Won Jin; Jaffee, Elizabeth; Fertig, Elana; Zaidi, Neeha 分享 收藏
Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence Zhang, Shuming; Yuan, Long; Danilova, Ludmila; Mo, Guanglan; Zhu, Qingfeng; Deshpande, Atul; Bell, Alexander T. F.; Elisseeff, Jennifer; Popel, Aleksander S.; Anders, Robert A.; Jaffee, Elizabeth M.; Yarchoan, Mark; Fertig, Elana J.; Kagohara, Luciane T. 分享 收藏
Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces (vol 14, pg 285, 2023) Deshpande, Atul; Loth, Melanie; Sidiropoulos, Dimitrios N.; Zhang, Shuming; Yuan, Long; Bell, Alexander T. F.; Zhu, Qingfeng; Ho, Won Jin; Santa-Maria, Cesar; Gilkes, Daniele M.; Williams, Stephen R.; Uytingco, Cedric R.; Chew, Jennifer; Hartnett, Andrej; Bent, Zachary W.; V. Favorov, Alexander; Popel, Aleksander S.; Yarchoan, Mark; Kiemen, Ashley; Wu, Pei-Hsun; Fujikura, Kohei; Wirtz, Denis; Wood, Laura D.; Zheng, Lei; Jaffee, Elizabeth M.; Anders, Robert A.; Danilova, Ludmila; Stein-O'Brien, Genevieve; Kagohara, Luciane T.; Fertig, Elana J. 分享 收藏
Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces Deshpande, Atul; Loth, Melanie; Sidiropoulos, Dimitrios N.; Zhang, Shuming; Yuan, Long; Bell, Alexander T. F.; Zhu, Qingfeng; Ho, Won Jin; Santa-Maria, Cesar; Gilkes, Daniele M.; Williams, Stephen R.; Uytingco, Cedric R.; Chew, Jennifer; Hartnett, Andrej; Bent, Zachary W.; Favorov, Alexander V.; Popel, Aleksander S.; Yarchoan, Mark; Kiemen, Ashley; Wu, Pei-Hsun; Fujikura, Kohei; Wirtz, Denis; Wood, Laura D.; Zheng, Lei; Jaffee, Elizabeth M.; Anders, Robert A.; Danilova, Ludmila; Stein-O'Brien, Genevieve; Kagohara, Luciane T.; Fertig, Elana J. 分享 收藏
分享 收藏
分享 收藏
.png){kind=icon}
.png){kind=icon}
.png)
CANCER RESEARCH.png)
.png){kind=icon}
分享.png){kind=icon}
收藏