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E

Elizabeth M. Jaffee

Johns Hopkins University
H指数:112
被引数:5.6万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Copanlisib in combination with nivolumab formicrosatellite stable colorectal cancer: a phase 1/2 trial

奥拉帕尼与尼沃鲁单抗联合治疗微卫星稳定型结直肠癌：一项1/2期临床试验

Nature Communications
IF15.7
2026-07-230
OA
Eric S. Christenson; Jeremiah A. Wala; Rose Parkinson; Natalie B. Collins; Christopher Jakubowski; Jia-Ren Lin; Kristin Qian; Jiayun Lu; Hao Wang; Won Jin Ho; Sabrina Chan; Ewa Kulikowicz; Rachel Klein; Yvette Cetasaan; Emma Johnson; Maureen Berg; Jeffrey A. Meyerhardt; Dung T. Le; Benjamin L. Schlechter; Ilene Browner; Lei Zheng; Harshabad Singh; Ross Donehower; Elizabeth M. Jaffee; Peter K. Sorger; Marios Giannakis; Nilofer Azad
Mutant KRAS peptide vaccine with dual checkpoint blockade in metastatic colorectal cancer: a phase I trial

携带KRAS突变肽疫苗及双重检查点封锁的转移性结直肠癌：一项I期临床试验

Nature Communications
IF15.7
2026-06-230
OAAI
Hejia Henry Wang; Amanda L. Huff; S. Daniel Haldar; Maureen Berg; Christopher Thoburn; Thatcher R. Heumann; Robert A. Anders; Benjamin Barrett; Katherine M. Bever; Michael J. Pishvaian; Valerie Lee; Dung T. Le; Eric S. Christenson; Marina Baretti; Mark Yarchoan; Daniel Laheru; Amy Thomas; Jennifer N. Durham; Julie M. Nauroth; Jiayun Lu; Hao Wang; Elizabeth M. Jaffee; Nilofer S. Azad; Neeha Zaidi
Publisher Correction: Mutant KRAS vaccine with dual checkpoint blockade in resected pancreatic cancer: a phase I trial

Publisher Correction: 突变KRAS疫苗联合双重免疫检查点阻断在切除的胰腺癌中的I期临床试验

Nature Communications
IF15.7
2026-04-150
OAAI
Amanda L. Huff; S. Daniel Haldar; Alexander A. Girgis; Hejia Henry Wang; Ludmila Danilova; Thatcher Heumann; Maureen Berg; Yuxuan Wang; Lalitya Andaloori; Alexei Hernandez; Gabriella Longway; Benjamin Barrett; Zirui Zhu; Emily Davis-Marcisak; Christopher Thoburn; James Leatherman; Sarah Mitchell; Jae W. Lee; Daniel H. Shu; Maximillian F. Konig; Brian J. Mog; Janelle Montagne; Erin M. Coyne; Katherine Bever; Marina Baretti; Mark Yarchoan; Robert A. Anders; Luciane T. Kagohara; Daniel Laheru; Amy M. Thomas; Jennifer Durham; Julie M. Nauroth; Jiayun Lu; Hao Wang; Elana J. Fertig; Won Jin Ho; Nilofer S. Azad; Elizabeth M. Jaffee; Neeha Zaidi
The combination of a cancer vaccine, pembrolizumab, and stereotactic body radiation in patients with locally advanced pancreatic cancer: a single-arm, phase II study

联合使用癌症疫苗、pembrolizumab 和立体定向体部放射治疗局部晚期胰腺癌患者的疗效：一项单臂、II 期研究

Nature Communications
IF15.7
2026-03-180
OAAI
Valerie Lee; Apoorvaa S. Sachidanand; Christina Rodriguez; Junke Wang; Beth Onners; Hanfei Qi; Rose Parkinson; Thomas McPhaul; Jennifer Durham; Ding Ding; Amy Hacker-Prietz; Amol K. Narang; Dung T. Le; Ana De Jesus; Michael Pishvaian; Eric Christenson; Elizabeth D. Thompson; Robert A. Anders; Arsen Osipov; Matthew Weiss; William Burns; Richard Burkhart; Kelly Lafaro; Jin He; Christopher L. Wolfgang; Elizabeth Sugar; Joseph M. Herman; Elizabeth M. Jaffee; Hao Wang; Daniel A. Laheru; Lei Zheng
Mutant KRAS vaccine with dual checkpoint blockade in resected pancreatic cancer: a phase I trial

携带双检查点阻断的突变KRAS疫苗在切除的胰腺癌中的应用：一项I期临床试验

Nature Communications
IF15.7
2026-02-100
OAAI
Amanda L. Huff; S. Daniel Haldar; Alexander A. Gergis; Hejia Henry Wang; Ludmila Danilova; Thatcher Heumann; Maureen Berg; Yuxuan Wang; Lalitya Andaloori; Alexei Hernandez; Gabriella Longway; Benjamin Barrett; Zirui Zhu; Emily Davis-Marcisak; Christopher Thoburn; James Leatherman; Sarah Mitchell; Jae W. Lee; Daniel H. Shu; Maximillian F. Konig; Brian J. Mog; Janelle Montagne; Erin M. Coyne; Katherine Bever; Marina Baretti; Mark Yarchoan; Robert A. Anders; Luciane T. Kagohara; Daniel Laheru; Amy M. Thomas; Jennifer Durham; Julie M. Nauroth; Jiayun Lu; Hao Wang; Elana J. Fertig; Won Jin Ho; Nilofer S. Azad; Elizabeth M. Jaffee; Neeha Zaidi
An integrated single-cell and spatial transcriptomic atlas of thyroid cancer progression identifies prognostic fibroblast subpopulations

甲状腺癌进展的整合单细胞和空间转录组学图谱鉴定出具有预后价值的成纤维细胞亚群

JCI Insight
IF6.1
2026-01-090
PRE
Loberg, Matthew A.; Xu, George J.; Chen, Sheau-Chiann; Chen, Hua-Chang; Wahoski, Claudia C.; Caroland, Kailey P.; Tigue, Megan L.; Hartmann, Heather A.; Gallant, Jean-Nicolas; Phifer, Courtney J.; Ocampo, Andres A.; Wang, Dayle K.; Fankhauser, Reilly G.; Karunakaran, Kirti A.; Wu, Chia-Chin; Tarabichi, Maxime; Shaddy, Sophia M.; Netterville, James L.; Rohde, Sarah L.; Solorzano, Carmen C.; Bischoff, Lindsay A.; Baregamian, Naira; Murphy, Barbara A.; Choe, Jennifer H.; Wang, Jennifer R.; Huang, Eric C.; Sheng, Quanhu; Kagohara, Luciane T.; Jaffee, Elizabeth M.; Belcher, Ryan H.; Lau, Ken S.; Ye, Fei; Lee, Ethan; Weiss, Vivian L.
Synthetic long peptide and DNA personalized cancer vaccines induce robust neoantigen-specific T cell responses in pancreatic cancer

合成长肽和DNA个性化癌症疫苗在胰腺癌中诱导强烈的neoantigen特异性T细胞反应

Science Advances
IF12.5
2026-01-010
OA
Felicia Zhang Perkins; Xiuli Zhang; Yik Y. L. Yu; Yilin Yang; Darren Cullinan; Kartik Singhal; Carlos Parra-López; Christopher A. Miller; Binghan Yan; Julia W. Angkeow; Jinglun Li; Nancy B. Myers; Tammi L. Vickery; John M. Herndon; Rashmi Mishra; Stephanie Myles; Dominic Sanford; Elizabeth M. Jaffee; Daniel A. Laheru; Andrea Wang‐Gillam; Marianna B. Ruzinova; Ian S. Hagemann; Sherri R. Davies; Timothy P. Fleming; Shelby L. Namen; Carl J. DeSelm; Lijin Li; Roheena Z. Panni; Feng Gao; Kian‐Huat Lim; Obi L. Griffith; Malachi Griffith; Robert D. Schreiber; Simon Peter Goedegebuure; William G. Hawkins; William E. Gillanders
Comparative assessment of physiochemical metrics for the clustering of adaptive immune receptor repertoires

适应性免疫受体库聚类中物理化学指标的对比评估

NUCLEIC ACIDS RESEARCH
IF13.1
2025-11-260
OAAI
Girgis, Alexander A.; Huff, Amanda L.; Davis-Marcisak, Emily; Palmer, Theron; Wang, Hanzhi; Kagohara, Luciane T.; Montagne, Janelle M.; Lvovs, Dmitrijs; Danilova, Ludmila; Favorov, Alexander, V; Schneck, Jonathan; Bingham III, Clifton O.; Darrah, Erika; Jaffee, Elizabeth M.; Zaidi, Neeha; Afsari, Bahman; Fertig, Elana J.
A therapeutic peptide vaccine for fibrolamellar hepatocellular carcinoma: a phase 1 trial

一种纤维层状肝细胞癌的治疗性多肽疫苗：一项1期临床试验

Nature Medicine
IF50
2025-11-240
OAAI
Marina Baretti; Allison M. Kirk; Brian H. Ladle; Zeal Kamdar; Kayla J. Bendinelli; Won Jin Ho; Samir Adhikari; Nicholas A. Clark; Balaji Sundararaman; Hao Wang; Heng-Chung Kung; Jeric Hernandez; Hanfei Qi; Sarah M. Shin; Alexei Hernandez; Mari Nakazawa; Stefan A. Schattgen; Jeremy Chase Crawford; Mark Furth; Robert A. Anders; Chris Thoburn; Neeha Zaidi; Amanda L. Huff; Julie Nauroth; Elizabeth Jaffee; Mikhail V. Pogorelyy; Paul G. Thomas; Mark Yarchoan
DNAJ-PKAc induces metabolic rewiring and enhanced glutamine flux in fibrolamellar HCC

DNAJ-PKAc诱导纤维层状肝细胞癌的代谢重编程及谷氨酰胺通量增强

Journal of Hepatology
IF33
2025-11-060
PRE
Zeal Kamdar; Ethan Neumann; Kathryn Howe; Donald Long; Waqar Arif; Daniel H. Shu; Aditya Mohan; Emma Kartalia; Jeric Hernandez; Solomon Levin; Kylie Belanger; Kayla Bendinelli; Tamara Y. Lopez-Vidal; James M. Leatherman; Kabeer Munjal; Cissy Zhang; Pratik Khare; Paul G. Thomas; Daniel J. Zabransky; Won Jin Ho; Robert D. Leone; Robert A. Anders; Anne Le; Praveen Sethupathy; Chi V. Dang; Elizabeth M. Jaffee; Mark Yarchoan
Immune Activation Signatures Associated with Fatigue in Cancer Patients Undergoing Immune Checkpoint Inhibitor Therapy

与接受免疫检查点抑制剂治疗的癌症患者疲劳相关的免疫激活特征

CANCER RESEARCH COMMUNICATIONS
IF0
2025-10-010
OAAI
Li, Howard L.; Charmsaz, Soren; Nakazawa, Mari; Alden, Stephanie L.; Brancati, Madelena; Leatherman, James M.; Griffin, Ervin; Tsai, Hua-Ling; Gross, Nicole E.; Thoburn, Christopher J.; Hernandez, Alexei; Coyne, Erin M.; Shin, Sarah M.; Lee, Royce P.; Lipson, Evan J.; Johnson III, Burles A.; Pabani, Aliyah; Ged, Yasser; Baretti, Marina; Brahmer, Julie R.; Hoffman-Censits, Jean; Seiwert, Tanguy Y.; Zabransky, Daniel J.; Durham, Jennifer N.; Jaffee, Elizabeth M.; Chandler, G. Scott; Adler, Brittany L.; Ho, Won Jin; Kao, Chester; Yarchoan, Mark
A phase 2 trial of CXCR4 antagonism and PD1 inhibition in metastatic pancreatic adenocarcinoma reveals recruitment of T cells but also immunosuppressive macrophages

一项关于CXCR4拮抗和PD1抑制在转移性胰腺腺癌中的Ⅱ期试验显示，招募了T细胞但也招募了免疫抑制性巨噬细胞。

OncoImmunology
IF6.3
2025-08-150
OAAI
Katherine M. Bever; Sarah M. Shin; Jennifer N. Durham; Hanfei Qi; Alexei Hernandez; Erin M. Coyne; Nicole E. Gross; Soren Charmsaz; Jayalaxmi Suresh Babu; Diana Carolina Vargas Carvajal; Rohan Verma; Yanyi Sun; Zhehao Zhang; Xuan Yuan; Courtney D. Cannon; Sarah N. Hughes; Sarah Mitchell; Madeline Figlewski; James M. Leatherman; Hao Wang; Robert A. Anders; Elizabeth M. Jaffee; Dung T. Le; Won Jin Ho
Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories

人类可解释的语法对多细胞系统生物学模型进行编码，以实现虚拟细胞实验室的民主化。

Cell
IF42.5
2025-07-260
OAAI
Jeanette A.I. Johnson; Daniel R. Bergman; Heber L. Rocha; David L. Zhou; Eric Cramer; Ian C. Mclean; Yoseph W. Dance; Max Booth; Zachary Nicholas; Tamara Lopez-Vidal; Atul Deshpande; Randy Heiland; Elmar Bucher; Fatemeh Shojaeian; Matthew Dunworth; André Forjaz; Michael Getz; Inês Godet; Furkan Kurtoglu; Melissa Lyman; John Metzcar; Jacob T. Mitchell; Andrew Raddatz; Jacobo Solorzano; Aneequa Sundus; Yafei Wang; David G. DeNardo; Andrew J. Ewald; Daniele M. Gilkes; Luciane T. Kagohara; Ashley L. Kiemen; Elizabeth D. Thompson; Denis Wirtz; Laura D. Wood; Pei-Hsun Wu; Neeha Zaidi; Lei Zheng; Jacquelyn W. Zimmerman; Jude M. Phillip; Elizabeth M. Jaffee; Joe W. Gray; Lisa M. Coussens; Young Hwan Chang; Laura M. Heiser; Genevieve L. Stein-O’Brien; Elana J. Fertig; Paul Macklin
Age-related divergence of circulating immune responses in patients with solid tumors treated with immune checkpoint inhibitors

实体瘤患者接受免疫检查点抑制剂治疗后，年龄相关的循环免疫反应差异

NATURE COMMUNICATIONS
IF15.7
2025-04-210
OA
Kao, Chester; Charmsaz, Soren; Tsai, Hua-Ling; Aziz, Khaled; Shu, Daniel H.; Munjal, Kabeer; Griffin, Ervin; Leatherman, James M.; Lipson, Evan J.; Ged, Yasser; Hoffman-Censits, Jeannie; Li, Howard L.; Hallab, Elsa; Brancati, Madelena; Nakazawa, Mari; Alden, Stephanie; Thoburn, Christopher; Gross, Nicole E.; Hernandez, Alexei G.; Coyne, Erin M.; Kartalia, Emma; Baretti, Marina; Jaffee, Elizabeth M.; Bansal, Sanjay; Tang, Laura; Chandler, G. Scott; Mohindra, Rajat; Ho, Won Jin; Yarchoan, Mark; Zabransky, Daniel J.
EphA2-targeted alpha-particle theranostics for PDAC treatment

EphA2靶向α粒子诊疗一体化在PDAC治疗中的应用

THERANOSTICS
IF13.3
2025-03-180
OA
Sharma, Ajay Kumar; Gupta, Kuldeep; Mishra, Akhilesh; Lofland, Gabriela; Chen, Sophia Y.; Marsh, Ian; Fair, Peyton T.; Hobbs, Robert F.; Armstrong, Todd M.; Jaffee, Elizabeth M.; Gabrielson, Edward W.; Zheng, Lei; Nimmagadda, Sridhar
Phase 1 Study of Adjuvant Allogeneic Granulocyte-Macrophage Colony-Stimulating Factor-Transduced Pancreatic Tumor Cell Vaccine, Low-Dose Cyclophosphamide, and Stereotactic Body Radiation Therapy Followed by FOLFIRINOX in High-Risk Resected Pancreatic Ductal Adenocarcinoma
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
IF6.5
2025-03-011
PRE
Hill, Colin S.; Parkinson, Rose; Jaffee, Elizabeth M.; Sugar, Elizabeth; Zheng, Lei; Onners, Beth; Weiss, Matthew J.; Wolfgang, Christopher L.; Cameron, John L.; Pawlik, Timothy M.; Rosati, Lauren; Le, Dung T.; Hacker-Prietz, Amy; Lutz, Eric R.; Schulick, Richard; Narang, Amol K.; Laheru, Daniel A.; Herman, Joseph M.

研究方向

暂未获取到该数据
E
Elana J. Fertig
H 指数:54论文数:917被引数:1.1万
W
Won Jin Ho
H 指数:29论文数:367被引数:4,384
T
Todd D. Armstrong
H 指数:33论文数:338被引数:6,429
M
Mark Yarchoan
H 指数:51论文数:480被引数:1.7万
L
Lei Zheng
H 指数:69论文数:816被引数:1.9万
L
Luciane T. Kagohara
H 指数:23论文数:410被引数:2,249
N
Neeha Zaidi
H 指数:27论文数:127被引数:3,532
D
Daniel A. Laheru
H 指数:77论文数:636被引数:3.6万
D
Dung T. Le
H 指数:66论文数:513被引数:4.8万
J
James M. Leatherman
H 指数:20论文数:222被引数:1,822