Elizabeth M. Jaffee - Publications, H-index & Citations

Elizabeth M. Jaffee

johns hopkins university school of medicine

112H指数

1.4K论文数

5.6W被引数

收录论文 309

发表时间

Copanlisib in combination with nivolumab formicrosatellite stable colorectal cancer: a phase 1/2 trial 奥拉帕尼与尼沃鲁单抗联合治疗微卫星稳定型结直肠癌：一项1/2期临床试验

Nature Communications

IF15.7

2026-07-23

OAAI

Eric S. Christenson; Jeremiah A. Wala; Rose Parkinson; Natalie B. Collins; Christopher Jakubowski; Jia-Ren Lin; Kristin Qian; Jiayun Lu; Hao Wang; Won Jin Ho; Sabrina Chan; Ewa Kulikowicz; Rachel Klein; Yvette Cetasaan; Emma Johnson; Maureen Berg; Jeffrey A. Meyerhardt; Dung T. Le; Benjamin L. Schlechter; Ilene Browner; Lei Zheng; Harshabad Singh; Ross Donehower; Elizabeth M. Jaffee; Peter K. Sorger; Marios Giannakis; Nilofer Azad

Mutant KRAS peptide vaccine with dual checkpoint blockade in metastatic colorectal cancer: a phase I trial 携带KRAS突变肽疫苗及双重检查点封锁的转移性结直肠癌：一项I期临床试验

Nature Communications

IF15.7

2026-06-23

OAAI

Hejia Henry Wang; Amanda L. Huff; S. Daniel Haldar; Maureen Berg; Christopher Thoburn; Thatcher R. Heumann; Robert A. Anders; Benjamin Barrett; Katherine M. Bever; Michael J. Pishvaian; Valerie Lee; Dung T. Le; Eric S. Christenson; Marina Baretti; Mark Yarchoan; Daniel Laheru; Amy Thomas; Jennifer N. Durham; Julie M. Nauroth; Jiayun Lu; Hao Wang; Elizabeth M. Jaffee; Nilofer S. Azad; Neeha Zaidi

Publisher Correction: Mutant KRAS vaccine with dual checkpoint blockade in resected pancreatic cancer: a phase I trial Publisher Correction: 突变KRAS疫苗联合双重免疫检查点阻断在切除的胰腺癌中的I期临床试验

Nature Communications

IF15.7

2026-04-15

OAAI

Amanda L. Huff; S. Daniel Haldar; Alexander A. Girgis; Hejia Henry Wang; Ludmila Danilova; Thatcher Heumann; Maureen Berg; Yuxuan Wang; Lalitya Andaloori; Alexei Hernandez; Gabriella Longway; Benjamin Barrett; Zirui Zhu; Emily Davis-Marcisak; Christopher Thoburn; James Leatherman; Sarah Mitchell; Jae W. Lee; Daniel H. Shu; Maximillian F. Konig; Brian J. Mog; Janelle Montagne; Erin M. Coyne; Katherine Bever; Marina Baretti; Mark Yarchoan; Robert A. Anders; Luciane T. Kagohara; Daniel Laheru; Amy M. Thomas; Jennifer Durham; Julie M. Nauroth; Jiayun Lu; Hao Wang; Elana J. Fertig; Won Jin Ho; Nilofer S. Azad; Elizabeth M. Jaffee; Neeha Zaidi

The combination of a cancer vaccine, pembrolizumab, and stereotactic body radiation in patients with locally advanced pancreatic cancer: a single-arm, phase II study 联合使用癌症疫苗、pembrolizumab 和立体定向体部放射治疗局部晚期胰腺癌患者的疗效：一项单臂、II 期研究

Nature Communications

IF15.7

2026-03-18

OAAI

Valerie Lee; Apoorvaa S. Sachidanand; Christina Rodriguez; Junke Wang; Beth Onners; Hanfei Qi; Rose Parkinson; Thomas McPhaul; Jennifer Durham; Ding Ding; Amy Hacker-Prietz; Amol K. Narang; Dung T. Le; Ana De Jesus; Michael Pishvaian; Eric Christenson; Elizabeth D. Thompson; Robert A. Anders; Arsen Osipov; Matthew Weiss; William Burns; Richard Burkhart; Kelly Lafaro; Jin He; Christopher L. Wolfgang; Elizabeth Sugar; Joseph M. Herman; Elizabeth M. Jaffee; Hao Wang; Daniel A. Laheru; Lei Zheng

Mutant KRAS vaccine with dual checkpoint blockade in resected pancreatic cancer: a phase I trial 携带双检查点阻断的突变KRAS疫苗在切除的胰腺癌中的应用：一项I期临床试验

Nature Communications

IF15.7

2026-02-10

OAAI

Amanda L. Huff; S. Daniel Haldar; Alexander A. Gergis; Hejia Henry Wang; Ludmila Danilova; Thatcher Heumann; Maureen Berg; Yuxuan Wang; Lalitya Andaloori; Alexei Hernandez; Gabriella Longway; Benjamin Barrett; Zirui Zhu; Emily Davis-Marcisak; Christopher Thoburn; James Leatherman; Sarah Mitchell; Jae W. Lee; Daniel H. Shu; Maximillian F. Konig; Brian J. Mog; Janelle Montagne; Erin M. Coyne; Katherine Bever; Marina Baretti; Mark Yarchoan; Robert A. Anders; Luciane T. Kagohara; Daniel Laheru; Amy M. Thomas; Jennifer Durham; Julie M. Nauroth; Jiayun Lu; Hao Wang; Elana J. Fertig; Won Jin Ho; Nilofer S. Azad; Elizabeth M. Jaffee; Neeha Zaidi

An integrated single-cell and spatial transcriptomic atlas of thyroid cancer progression identifies prognostic fibroblast subpopulations 甲状腺癌进展的整合单细胞和空间转录组学图谱鉴定出具有预后价值的成纤维细胞亚群

JCI Insight

IF6.1

2026-01-09

PREAI

Loberg, Matthew A.; Xu, George J.; Chen, Sheau-Chiann; Chen, Hua-Chang; Wahoski, Claudia C.; Caroland, Kailey P.; Tigue, Megan L.; Hartmann, Heather A.; Gallant, Jean-Nicolas; Phifer, Courtney J.; Ocampo, Andres A.; Wang, Dayle K.; Fankhauser, Reilly G.; Karunakaran, Kirti A.; Wu, Chia-Chin; Tarabichi, Maxime; Shaddy, Sophia M.; Netterville, James L.; Rohde, Sarah L.; Solorzano, Carmen C.; Bischoff, Lindsay A.; Baregamian, Naira; Murphy, Barbara A.; Choe, Jennifer H.; Wang, Jennifer R.; Huang, Eric C.; Sheng, Quanhu; Kagohara, Luciane T.; Jaffee, Elizabeth M.; Belcher, Ryan H.; Lau, Ken S.; Ye, Fei; Lee, Ethan; Weiss, Vivian L.

Comparative assessment of physiochemical metrics for the clustering of adaptive immune receptor repertoires 适应性免疫受体库聚类中物理化学指标的对比评估

NUCLEIC ACIDS RESEARCH

IF13.1

2025-11-26

OAAI

Girgis, Alexander A.; Huff, Amanda L.; Davis-Marcisak, Emily; Palmer, Theron; Wang, Hanzhi; Kagohara, Luciane T.; Montagne, Janelle M.; Lvovs, Dmitrijs; Danilova, Ludmila; Favorov, Alexander, V; Schneck, Jonathan; Bingham III, Clifton O.; Darrah, Erika; Jaffee, Elizabeth M.; Zaidi, Neeha; Afsari, Bahman; Fertig, Elana J.

A therapeutic peptide vaccine for fibrolamellar hepatocellular carcinoma: a phase 1 trial 一种纤维层状肝细胞癌的治疗性多肽疫苗：一项1期临床试验

Nature Medicine

IF50

2025-11-24

OAAI

Marina Baretti; Allison M. Kirk; Brian H. Ladle; Zeal Kamdar; Kayla J. Bendinelli; Won Jin Ho; Samir Adhikari; Nicholas A. Clark; Balaji Sundararaman; Hao Wang; Heng-Chung Kung; Jeric Hernandez; Hanfei Qi; Sarah M. Shin; Alexei Hernandez; Mari Nakazawa; Stefan A. Schattgen; Jeremy Chase Crawford; Mark Furth; Robert A. Anders; Chris Thoburn; Neeha Zaidi; Amanda L. Huff; Julie Nauroth; Elizabeth Jaffee; Mikhail V. Pogorelyy; Paul G. Thomas; Mark Yarchoan

DNAJ-PKAc induces metabolic rewiring and enhanced glutamine flux in fibrolamellar HCC DNAJ-PKAc诱导纤维层状肝细胞癌的代谢重编程及谷氨酰胺通量增强

Journal of Hepatology

IF33

2025-11-06

PREAI

Zeal Kamdar; Ethan Neumann; Kathryn Howe; Donald Long; Waqar Arif; Daniel H. Shu; Aditya Mohan; Emma Kartalia; Jeric Hernandez; Solomon Levin; Kylie Belanger; Kayla Bendinelli; Tamara Y. Lopez-Vidal; James M. Leatherman; Kabeer Munjal; Cissy Zhang; Pratik Khare; Paul G. Thomas; Daniel J. Zabransky; Won Jin Ho; Robert D. Leone; Robert A. Anders; Anne Le; Praveen Sethupathy; Chi V. Dang; Elizabeth M. Jaffee; Mark Yarchoan

BIWT: a bioinformatics walkthrough for embedding spatial multiomics in agent-based models for virtual cells

BIOINFORMATICS

IF5.4

2025-11-01

OAAI

Bergman, Daniel R.; Johnson, Jeanette A. I.; Naji, Marwa; Booth, Max; da Rocha, Heber Lima; Deshpande, Atul; Sidiropoulos, Dimitrios N.; Lopez-Vidal, Tamara; Heiland, Randy; Kagohara, Luciane T.; Anders, Robert A.; Zheng, Lei; Jaffee, Elizabeth M.; Stein-O'brien, Genevieve; Macklin, Paul; Fertig, Elana J.

Antigen-presenting cancer-associated fibroblasts in pancreatic ductal adenocarcinoma differentially regulate Treg phenotype and function via CXCL9 and CCL22

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Maru, Saumya Y.; Mitchell, Jacob T.; Wetzel, Meredith; Gross, Nicole E.; Andaloori, Lalitya; Howe, Kathryn; Kartalia, Emma; Mo, Guanglan; Leatherman, James; Ho, Won Jin; Fertig, Elana Judith; Kagohara, Luciane; Pearce, Edward J.; Jaffee, Elizabeth M.

CIRCUSS, a spatial immune receptor computational analysis tool, enables the characterization of therapeutic resistance to cancer immunotherapies

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Green, Benjamin F.; Montagne, Janelle Marie; Bell, Mulan; Taube, Janis Maire; Jaffee, Elizabeth M.; Kagohara, Luciane T.; Fertig, Elana Judith; Sidiropoulos, Dimitrios N.

Immune Activation Signatures Associated with Fatigue in Cancer Patients Undergoing Immune Checkpoint Inhibitor Therapy 与接受免疫检查点抑制剂治疗的癌症患者疲劳相关的免疫激活特征

CANCER RESEARCH COMMUNICATIONS

IF0

2025-10-01

OAAI

Li, Howard L.; Charmsaz, Soren; Nakazawa, Mari; Alden, Stephanie L.; Brancati, Madelena; Leatherman, James M.; Griffin, Ervin; Tsai, Hua-Ling; Gross, Nicole E.; Thoburn, Christopher J.; Hernandez, Alexei; Coyne, Erin M.; Shin, Sarah M.; Lee, Royce P.; Lipson, Evan J.; Johnson III, Burles A.; Pabani, Aliyah; Ged, Yasser; Baretti, Marina; Brahmer, Julie R.; Hoffman-Censits, Jean; Seiwert, Tanguy Y.; Zabransky, Daniel J.; Durham, Jennifer N.; Jaffee, Elizabeth M.; Chandler, G. Scott; Adler, Brittany L.; Ho, Won Jin; Kao, Chester; Yarchoan, Mark

A phase 2 trial of CXCR4 antagonism and PD1 inhibition in metastatic pancreatic adenocarcinoma reveals recruitment of T cells but also immunosuppressive macrophages 一项关于CXCR4拮抗和PD1抑制在转移性胰腺腺癌中的Ⅱ期试验显示，招募了T细胞但也招募了免疫抑制性巨噬细胞。

OncoImmunology

IF6.3

2025-08-15

OAAI

Katherine M. Bever; Sarah M. Shin; Jennifer N. Durham; Hanfei Qi; Alexei Hernandez; Erin M. Coyne; Nicole E. Gross; Soren Charmsaz; Jayalaxmi Suresh Babu; Diana Carolina Vargas Carvajal; Rohan Verma; Yanyi Sun; Zhehao Zhang; Xuan Yuan; Courtney D. Cannon; Sarah N. Hughes; Sarah Mitchell; Madeline Figlewski; James M. Leatherman; Hao Wang; Robert A. Anders; Elizabeth M. Jaffee; Dung T. Le; Won Jin Ho

Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories 人类可解释的语法对多细胞系统生物学模型进行编码，以实现虚拟细胞实验室的民主化。

Cell

IF42.5

2025-07-26

OAAI

Jeanette A.I. Johnson; Daniel R. Bergman; Heber L. Rocha; David L. Zhou; Eric Cramer; Ian C. Mclean; Yoseph W. Dance; Max Booth; Zachary Nicholas; Tamara Lopez-Vidal; Atul Deshpande; Randy Heiland; Elmar Bucher; Fatemeh Shojaeian; Matthew Dunworth; André Forjaz; Michael Getz; Inês Godet; Furkan Kurtoglu; Melissa Lyman; John Metzcar; Jacob T. Mitchell; Andrew Raddatz; Jacobo Solorzano; Aneequa Sundus; Yafei Wang; David G. DeNardo; Andrew J. Ewald; Daniele M. Gilkes; Luciane T. Kagohara; Ashley L. Kiemen; Elizabeth D. Thompson; Denis Wirtz; Laura D. Wood; Pei-Hsun Wu; Neeha Zaidi; Lei Zheng; Jacquelyn W. Zimmerman; Jude M. Phillip; Elizabeth M. Jaffee; Joe W. Gray; Lisa M. Coussens; Young Hwan Chang; Laura M. Heiser; Genevieve L. Stein-O’Brien; Elana J. Fertig; Paul Macklin

Recent advances in therapeutic cancer vaccines 治疗性癌症疫苗的研究进展

Nature Reviews Cancer

IF66.8

2025-05-16

PREAI

Zaidi, Neeha; Jaffee, Elizabeth M.; Yarchoan, Mark

NATURE COMMUNICATIONS

IF15.7

2025-04-21

OAAI

Kao, Chester; Charmsaz, Soren; Tsai, Hua-Ling; Aziz, Khaled; Shu, Daniel H.; Munjal, Kabeer; Griffin, Ervin; Leatherman, James M.; Lipson, Evan J.; Ged, Yasser; Hoffman-Censits, Jeannie; Li, Howard L.; Hallab, Elsa; Brancati, Madelena; Nakazawa, Mari; Alden, Stephanie; Thoburn, Christopher; Gross, Nicole E.; Hernandez, Alexei G.; Coyne, Erin M.; Kartalia, Emma; Baretti, Marina; Jaffee, Elizabeth M.; Bansal, Sanjay; Tang, Laura; Chandler, G. Scott; Mohindra, Rajat; Ho, Won Jin; Yarchoan, Mark; Zabransky, Daniel J.

EphA2-targeted alpha-particle theranostics for PDAC treatment EphA2靶向α粒子诊疗一体化在PDAC治疗中的应用

THERANOSTICS

IF13.3

2025-03-18

OAAI

Sharma, Ajay Kumar; Gupta, Kuldeep; Mishra, Akhilesh; Lofland, Gabriela; Chen, Sophia Y.; Marsh, Ian; Fair, Peyton T.; Hobbs, Robert F.; Armstrong, Todd M.; Jaffee, Elizabeth M.; Gabrielson, Edward W.; Zheng, Lei; Nimmagadda, Sridhar

Phase 1 Study of Adjuvant Allogeneic Granulocyte-Macrophage Colony-Stimulating Factor-Transduced Pancreatic Tumor Cell Vaccine, Low-Dose Cyclophosphamide, and Stereotactic Body Radiation Therapy Followed by FOLFIRINOX in High-Risk Resected Pancreatic Ductal Adenocarcinoma

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

IF6.5

2025-03-01

PREAI

Hill, Colin S.; Parkinson, Rose; Jaffee, Elizabeth M.; Sugar, Elizabeth; Zheng, Lei; Onners, Beth; Weiss, Matthew J.; Wolfgang, Christopher L.; Cameron, John L.; Pawlik, Timothy M.; Rosati, Lauren; Le, Dung T.; Hacker-Prietz, Amy; Lutz, Eric R.; Schulick, Richard; Narang, Amol K.; Laheru, Daniel A.; Herman, Joseph M.

Stromal changes in the aged lung induce an emergence from melanoma dormancy (vol 606, pg 396, 2022)老年肺的间质变化诱导黑色素瘤休眠状态的终止（vol 606, pg 396, 2022）

NATURE

IF48.5

2025-01-31

PREAI

Fane, Mitchell E.; Chhabra, Yash; Alicea, Gretchen M.; Maranto, Devon A.; Douglass, Stephen M.; Webster, Marie R.; Rebecca, Vito W.; Marino, Gloria E.; Almeida, Filipe; Ecker, Brett L.; Zabransky, Daniel J.; Huser, Laura; Beer, Thomas; Tang, Hsin-Yao; Kossenkov, Andrew; Herlyn, Meenhard; Speicher, David W.; Xu, Wei; Xu, Xiaowei; Jaffee, Elizabeth M.; Aguirre-Ghiso, Julio A.; Weeraratna, Ashani T.

研究方向