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A

Andreas Krämer

Goethe University Frankfurt
H指数:26
被引数:2,480

个人简介

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工作经历

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荣誉奖项

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DHODH is the key target of the KDM4 inhibitor QC6352 in glioblastoma stem cells

DHODH是KDM4抑制剂QC6352在胶质母细胞瘤干细胞中的关键靶点

Nature Chemical Biology
IF13.7
2026-10-060
OA
Jayden R. Sterling; Jacinda R. Holtsmark; George L. Joun; Matthew S. Graus; Tian Y. Du; Mani Kuchibhotla; Terrance G. Johns; Antoine deWeck; Lipin Loo; G. Gregory Neely; Karen Tran; Chloe Shard; Guillermo A. Gomez; Ashwini Patil; Diana D. Shi; Julie-Aurore Losman; Angus J. Saxton; Jennifer R. Baker; Zhihe Lei; Matthew T. O. Holland; Paul E. Brennan; Mathias Francois; Andreas Kraemer; Susanne Mueller; Yuchen Feng; Paul Workman; Lenka Munoz
Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1

核碱基催化剂用于酶促激活8-oxoguanine DNA glycosylase 1

RSC Chem. Biol.
IF3.1
2025-10-290
OAAI
Emily C. Hank; Nicholas D'Arcy-Evans; Emma Rose Scaletti; Carlos Benítez-Buelga; Olov Wallner; Florian Ortis; Kaixin Zhou; Liuzhen Meng; Alicia del Prado; Patricia Calvo; Ingrid Almlöf; Elisee Wiita; Karen Nierlin; Sara Kosenina; Andreas Krämer; Alice Eddershaw; Mario Kehler; Maeve Long; AnnSofie Jemth; Holly Dawson; Josephine Stewart; Adam Dickey; Mikhael Elijah Astorga; Marek Varga; Evert Homan; Martin Scobie; Stefan Knapp; Leandro Sastre; Pål Stenmark; Miguel de Vega; Thomas Helleday; Maurice Michel
Un-LOK-ing a New Approach for Conformational Selective Targeting of STK10 (LOK)

解锁一种针对STK10（LOK）构象选择性靶向的新方法

ACS Medicinal Chemistry Letters
IF4
2025-10-130
OAAI
Martina Dettenhöfer; Laura Nadine Tandara; Jennifer Alisa Amrhein; Christian Georg Kurz; Martin Peter Schwalm; Theresa Elisabeth Mensing; Laurenz Maximilian Wahl; Andreas Krämer; Joshua Gerninghaus; Christopher Lenz; Lewis Elson; Benedict-Tilman Berger; Martin Schröder; Krishna Saxena; Susanne Müller; Stefan Knapp; Francesco Aleksy Greco; Thomas Hanke
Covalent Targeting Leads to the Development of a LIMK1 Isoform-Selective Inhibitor

共价靶向导致LIMK1亚型选择性抑制剂的研发

Journal of Medicinal Chemistry
IF6.8
2025-07-020
OA
Sebastian Mandel; Thomas Hanke; Niall Prendiville; María Baena-Nuevo; Lena Marie Berger; Frederic Farges; Martin Peter Schwalm; Benedict-Tilman Berger; Andreas Kraemer; Lewis Elson; Hayuningbudi Saraswati; Kamal R. Abdul Azeez; Verena Dederer; Sebastian Mathea; Ana Corrionero; Patricia Alfonso; Sabrina Keller; Matthias Gstaiger; Daniela S. Krause; Susanne Müller; Sandra Röhm; Stefan Knapp
Repurposing of the RIPK1-Selective Benzo[1,4]oxazepin-4-one Scaffold for the Development of a Type III LIMK1/2 Inhibitor
ACS CHEMICAL BIOLOGY
IF3.8
2025-04-010
OAAI
Mandel, Sebastian; Hanke, Thomas; Mathea, Sebastian; Chatterjee, Deep; Saraswati, Hayuningbudi; Berger, Benedict-Tilman; Schwalm, Martin Peter; Yamamoto, Satoshi; Tawada, Michiko; Takagi, Terufumi; Ahmed, Mahmood; Roehm, Sandra; Corrionero, Ana; Alfonso, Patricia; Baena, Maria; Elson, Lewis; Menge, Amelie; Kraemer, Andreas; Pereira, Raquel; Mueller, Susanne; Krause, Daniela S.; Knapp, Stefan
More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-a]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-07-032
OAAI
Ong, Han Wee; Yang, Xuan; Smith, Jeffery L.; Dickmander, Rebekah J.; Brown, Jason W.; Havener, Tammy M.; Taft-Benz, Sharon; Howell, Stefanie; Sanders, Marcia K.; Capener, Jacob L.; Counago, Rafael M.; Chang, Edcon; Kraemer, Andreas; Moorman, Nathaniel J.; Heise, Mark; Axtman, Alison D.; Drewry, David H.; Willson, Timothy M.

研究方向

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S
Stefan Knapp
H 指数:111论文数:1,351被引数:4.8万
S
Susanne Müller
H 指数:71论文数:447被引数:2.0万
T
Thomas Hanke
H 指数:52论文数:364被引数:8,068
B
Benedict‐Tilman Berger
H 指数:24论文数:80被引数:1,730
L
Lewis Elson
H 指数:8论文数:36被引数:126
A
Andreas C. Joerger
H 指数:41论文数:127被引数:8,231
L
Lena M. Berger
H 指数:11论文数:32被引数:410
M
Martin P. Schwalm
H 指数:13论文数:66被引数:623
K
Krishna Saxena
H 指数:38论文数:226被引数:4,269
C
Christopher Lenz
H 指数:6论文数:35被引数:96