Kok‐Lung Chan - Publications, H-index & Citations

Kok‐Lung Chan

genome damage and stability centre

31H指数

73论文数

5.3K被引数

收录论文 24

发表时间

Centromere protection requires strict mitotic inactivation of the Bloom syndrome helicase complex 着丝点保护需要严格的Bloom综合征解旋酶复合物的有丝分裂失活。

Nature Communications

IF15.7

2025-08-22

OAAI

María Fernández-Casañas; Eleftheria Karanika; Umit Aliyaskarova; Tomisin Olukoga; Alex D. Herbert; Antony W. Oliver; Matthew Day; Adrijana Crncec; Kok-Lung Chan

FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics

CELL REPORTS

IF6.9

2023-07-01

OAAI

Stok, Colin; Tsaridou, Stavroula; van den Tempel, Nathalie; Everts, Marieke; Wierenga, Elles; Bakker, Femke J.; Kok, Yannick; Alves, Ines Teles; Jae, Lucas T.; Raas, Maximilian W. D.; in't Veld, Pim J. Huis; de Boer, H. Rudolf; Bhattacharya, Arkajyoti; Karanika, Eleftheria; Warner, Harry; Chen, Mengting; van de Kooij, Bert; Dessapt, Julien; ter Morsche, Lars; Perepelkina, Polina; Fradet-Turcotte, Amelie; Guryev, Victor; Tromer, Eelco C.; Chan, Kok-Lung; Fehrmann, Rudolf S. N.; van Vugt, Marcel A. T. M.

DNA replication is highly resilient and persistent under the challenge of mild replication stress

CELL REPORTS

IF6.9

2022-04-01

OAAI

Mocanu, Camelia; Karanika, Eleftheria; Fernandez-Casanas, Maria; Herbert, Alex; Olukoga, Tomisin; Ozgurses, Mete Emir; Chan, Kok-Lung

PLK1 facilitates chromosome biorientation by suppressing centromere disintegration driven by BLM-mediated unwinding and spindle pulling

NATURE COMMUNICATIONS

IF15.7

2019-06-28

OAAI

Jones, Owen Addis; Tiwari, Ankana; Olukoga, Tomisin; Herbert, Alex; Chan, Kok-Lung

53BP1 can limit sister-chromatid rupture and rearrangements driven by a distinct ultrafine DNA bridging-breakage process

NATURE COMMUNICATIONS

IF15.7

2018-02-14

OAAI

Tiwari, Ankana; Jones, Owen Addis; Chan, Kok-Lung

Well-Characterised Time-Gated Detector Photon Flux Resolves the Ultrastructure of DNA-Damage Nuclear Bodies with G-STED Nanoscopy

BIOPHYSICAL JOURNAL

IF3.1

2017-02-01

OAAI

Chan, Kok-Lung; Gonzalez, Esther Garcia; Padilla-Parra, Sergi; de la Serna, Jorge Bernardino

Releasing Activity Disengages Cohesin's Smc3/Scc1 Interface in a Process Blocked by Acetylation 释放活性在被乙酰化阻断的过程中使Cohesin的Smc3/Scc1界面脱离

MOLECULAR CELL

IF16.6

2016-02-01

OAAI

Beckouet, Frederic; Srinivasan, Madhusudhan; Roig, Maurici Brunet; Chan, Kok-Lung; Scheinost, Johanna C.; Batty, Paul; Hu, Bin; Petela, Naomi; Gligoris, Thomas; Smith, Alexandra C.; Strmecki, Lana; Rowland, Benjamin D.; Nasmyth, Kim

Biological chromodynamics: a general method for measuring protein occupancy across the genome by calibrating ChIP-seq

NUCLEIC ACIDS RESEARCH

IF13.1

2015-06-30

110

OAAI

Hu, Bin; Petela, Naomi; Kurze, Alexander; Chan, Kok-Lung; Chapard, Christophe; Nasmyth, Kim

On the origins of ultra-fine anaphase bridges

CELL CYCLE

IF3.4

2014-10-28

OAAI

Chan, Kok Lung; Hickson, Ian D.

Structure and function of cohesin's Scc3/SA regulatory subunit cohesin的Scc3/SA调节亚基的结构与功能

FEBS LETTERS

IF3

2014-08-27

OAAI

Roig, Maurici B.; Loewe, Jan; Chan, Kok-Lung; Beckouet, Frederic; Metson, Jean; Nasmyth, Kim

GOLIMUMAB VERSUS PAMIDRONATE FOR THE TREATMENT OF AXIAL SPONDYLOARTHROPATHY (SPA): A 48-WEEK RANDOMIZED CONTROLLED TRIAL

ANNALS OF THE RHEUMATIC DISEASES

IF20.6

2014-06-01

PREAI

Mok, C. C.; Li, A.; Chan, K. L.; Ho, L. Y.

Pds5 promotes and protects cohesin acetylation Pds5促进和保护cohesin乙酰化

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-07-22

102

OAAI

Chan, Kok-Lung; Gligoris, Thomas; Upcher, William; Kato, Yuki; Shirahige, Katsuhiko; Nasmyth, Kim; Beckouet, Frederic

MUS81 promotes common fragile site expression

NATURE CELL BIOLOGY

IF19.1

2013-06-30

226

PREAI

Ying, Songmin; Minocherhomji, Sheroy; Chan, Kok Lung; Palmai-Pallag, Timea; Chu, Wai Kit; Wass, Theresa; Mankouri, Hocine W.; Liu, Ying; Hickson, Ian D.

New insights into the formation and resolution of ultra-fine anaphase bridges

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

IF6

2011-10-01

PREAI

Chan, Kok Lung; Hickson, Ian D.

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

NATURE CELL BIOLOGY

IF19.1

2011-02-13

584

PREAI

Lukas, Claudia; Savic, Velibor; Bekker-Jensen, Simon; Doil, Carsten; Neumann, Beate; Pedersen, Ronni Solvhoj; Grofte, Merete; Chan, Kok Lung; Hickson, Ian David; Bartek, Jiri; Lukas, Jiri

ATP Hydrolysis Is Required for Relocating Cohesin from Sites Occupied by Its Scc2/4 Loading Complex 从其Scc2/4负载复合物占据的位点重新定位凝聚素需要ATP水解

CURRENT BIOLOGY

IF7.5

2011-01-01

172

OAAI

Hu, Bin; Itoh, Takehiko; Mishra, Ajay; Katoh, Yuki; Chan, Kok-Lung; Upcher, William; Godlee, Camilla; Roig, Maurici B.; Shirahige, Katsuhiko; Nasmyth, Kim

Proteomics of Hepatocellular Carcinoma: Serum Vimentin As a Surrogate Marker for Small Tumors (≤2 cm)

JOURNAL OF PROTEOME RESEARCH

IF3.6

2010-02-02

PREAI

Sun, Stella; Poon, Ronnie T. P.; Lee, Nikki P.; Yeung, Chun; Chan, K. L.; Ng, Irene O. L.; Day, Philip J. R.; Luk, John M.

Replication stress induces sister-chromatid bridging at fragile site loci in mitosis

NATURE CELL BIOLOGY

IF19.1

2009-05-24

558

PREAI