未登录 Constitutive ALKS-independent C-jun N-terminal kinase activation contributes to endothelin-1 overexpression in pulmonary fibrosis: Evidence of an autocrine endothelin loop operating through the endothelin A and B receptors Xu Shi-Wen; Rodriguez-Pascual, Fernando; Lamas, Santiago; Holmes, Alan; Howat, Sarah; Pearson, Jeremy D.; Dashwood, Michael R.; du Bois, Roland M.; Denton, Christopher P.; Black, Carol M.; Abraham, David J.; Leask, Andrew 分享 收藏
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CCN2 is necessary for adhesive responses to transforming growth factor-β1 in embryonic fibroblasts Shi-Wen, X; Stanton, LA; Kennedy, L; Pala, D; Chen, YL; Howat, SL; Renzoni, EA; Carter, DE; Bou-Gharios, G; Stratton, RJ; Pearson, JD; Beier, F; Lyons, KM; Black, CM; Abraham, DJ; Leask, A 分享 收藏
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Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts Xu, SW; Chen, YL; Denton, CP; Eastwood, M; Renzoni, EA; Bou-Gharios, G; Pearson, JD; Dashwood, M; du Bois, RM; Black, CM; Leask, A; Abraham, DJ 分享 收藏
Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK Xu, SW; Howat, SL; Renzoni, EA; Holmes, A; Pearson, JD; Dashwood, MR; Bou-Gharios, G; Denton, CP; du Bois, RM; Black, CM; Leask, A; Abraham, DJ 分享 收藏