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K

Kevin A. Murray

University of California System

H指数:23

被引数:2,611

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Genetic and structural aspects of amyloid diseases

淀粉样变疾病的遗传和结构方面

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2025-10-010

PRE

Structure- based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-10-0612

OAAI

Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils

NATURE COMMUNICATIONS

IF15.7

2023-04-259

OAAI

Tayeb-Fligelman, Einav; Bowler, Jeannette T.; Tai, Christen E. E.; Sawaya, Michael R.; Jiang, Yi Xiao; Garcia, Gustavo; Griner, Sarah L.; Cheng, Xinyi; Salwinski, Lukasz; Lutter, Liisa; Seidler, Paul M.; Lu, Jiahui; Rosenberg, Gregory M.; Hou, Ke; Abskharon, Romany; Pan, Hope; Zee, Chih-Te; Boyer, David R.; Li, Yan; Anderson, Daniel H.; Murray, Kevin A.; Falcon, Genesis; Cascio, Duilio; Saelices, Lorena; Damoiseaux, Robert; Arumugaswami, Vaithilingaraja; Guo, Feng; Eisenberg, David S.

Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-02-0917

OAAI

Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro

NATURE COMMUNICATIONS

IF15.7

2022-09-1682

OAAI

De novo designed protein inhibitors of amyloid aggregation and seeding

从头设计的淀粉样蛋白聚集和接种的蛋白质抑制剂

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-08-1542

OA

Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2022-05-3015

OAAI

Bioinformatic identification of previously unrecognized amyloidogenic proteins

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-05-0113

OAAI

Extended β-Strands Contribute to Reversible Amyloid Formation

IF16

2022-02-0814

PRE

Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2021-09-0956

OA

Amyloid β-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation (vol 11, 86, 2019)

ALZHEIMERS RESEARCH & THERAPY

IF7.6

2021-04-192

OAAI

Inhibition of synucleinopathic seeding by rationally designed inhibitors

IF0

2020-01-0253

OA

RETRACTED: Different Amyloid-β Self-Assemblies Have Distinct Effects on Intracellular Tau Aggregation (Retracted article. See vol. 14, 2021)

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2019-11-0815

OAAI

Structure-based inhibitors halt prion-like seeding by Alzheimer's disease?and tauopathy?derived brain tissue samples

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-11-0160

OAAI

Amyloid β-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation

ALZHEIMERS RESEARCH & THERAPY

IF7.6

2019-10-1872

OAAI

Structure-based inhibitors of amyloid beta core suggest a common interface with tau

IF0

2019-10-1590

OA

SEIZURE PROPHYLAXIS IN GLIOMAS (SPRING): A PHASE III RANDOMISED CONTROLLED TRIAL COMPARING PROPHYLACTIC LEVETIRACETAM VERSUS NO PROPHYLACTIC ANTI-EPILEPTIC DRUG IN GLIOMA SURGERY

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

IF7.5

2019-02-147

PREAI

Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel

全长 α-突触核蛋白的cryo-em揭示了具有共同结构内核的原纤维多晶型物

NATURE COMMUNICATIONS

IF15.7

2018-09-06388

OAAI

Common fibrillar spines of amyloid-β and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-02-0158

OAAI

Structure-based inhibitors of tau aggregation

NATURE CHEMISTRY

IF20.2

2017-11-20255

OAAI