F. Jeffrey Dilworth - Publications, H-index & Citations

F. Jeffrey Dilworth

Ottawa Hospital Research Institute

48H指数

112论文数

7.1K被引数

收录论文 58

发表时间

TRF2 couples muscle stem cell identity to regenerative repair TRF2将肌肉干细胞特性与再生修复相偶联

Science Advances

IF12.5

2026-07-31

OAAI

Ji-Hyung Lee; Kiran Kumar Nakka; Ryan P. Calhoun; Sarah Hachmer; Adity Gupta; Eric Arreza; Lynn A. Megeney; Patrick Seale; Roger A. Greenberg; F. Jeffrey Dilworth; Foteini Mourkioti

Assessing the role of KMT2D in muscle regeneration to understand hypotonia symptoms associated with Kabuki Syndrome 评估KMT2D在肌肉再生中的作用，以理解Kabuki综合征相关的肌张力减退症状

CLINICAL CHEMISTRY

IF6.3

2025-10-01

OAAI

Hachmer, Sarah; Dilworth, F.

Epigenetic erosion of H4K20me1 induced by inflammation drives aged stem cell ferroptosis 炎症诱导的H4K20me1表观遗传侵蚀驱动衰老干细胞的铁死亡

Nature Aging

IF19.4

2025-06-30

OAAI

Roméo S. Blanc; Nidhi Shah; Sarah Hachmer; Noah A. S. Salama; Fanju W. Meng; Alireza Mousaei; Gayatri Puri; Jeonghye Hannah Hwang; Elizabeth E. Wacker; Benjamin A. Yang; Carlos A. Aguilar; Joe V. Chakkalakal; John O. Onukwufor; Patrick J. Murphy; Laura M. Calvi; F. Jeffrey Dilworth; Robert T. Dirksen

Capsular stem cell function and tissue composition are associated with symptoms and radiographic severity in people with knee osteoarthritis 囊干细胞功能和组织组成与膝骨关节炎患者的症状和影像学严重程度相关

THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE

IF4.1

2025-01-01

OAAI

Campbell, T. Mark; Feibel, Robert; Dilworth, Jeffrey; Laneuville, Odette; Trudel, Guy

SMCHD1 activates the expression of genes required for the expansion of human myoblasts

NUCLEIC ACIDS RESEARCH

IF13.1

2024-07-12

OAAI

Wong, Matthew Man-Kin; Hachmer, Sarah; Gardner, Ed; Runfola, Valeria; Arezza, Eric; Megeney, Lynn A.; Emerson Jr, Charles P.; Gabellini, Davide; Dilworth, F. Jeffrey

Statin-mediated reduction in mitochondrial cholesterol primes an anti-inflammatory response in macrophages by upregulating Jmjd3 他汀类药物通过降低线粒体胆固醇水平，进而上调Jmjd3表达，从而在巨噬细胞中启动抗炎反应。

ELIFE

IF0

2024-04-11

OAAI

Salloum, Zeina; Dauner, Kristin; Li, Yun-feng; Verma, Neha; Valdivieso-Gonzalez, David; Almendro-Vedia, Victor; Zhang, John D.; Nakka, Kiran; Chen, Mei Xi; Mcdonald, Jeffrey; Corley, Chase D.; Sorisky, Alexander; Song, Bao-Liang; Lopez-Montero, Ivan; Luo, Jie; Dilworth, Jeffrey F.; Zha, Xiaohui

Progeria-based vascular model identifies networks associated with cardiovascular aging and disease

AGING CELL

IF7.1

2024-04-04

OAAI

Ngubo, Mzwanele; Chen, Zhaoyi; McDonald, Darin; Karimpour, Rana; Shrestha, Amit; Yockell-Lelievre, Julien; Laurent, Aurelie; Besong, Ojong Tabi Ojong; Tsai, Eve C.; Dilworth, F. Jeffrey; Hendzel, Michael J.; Stanford, William L.

The novel transcription factor e(y)2 interacts with TAFII40 and potentiates transcription activation on chromatin templates

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Georgieva, S; Nabirochkina, E; Dilworth, FJ; Eickhoff, H; Becker, P; Tora, L; Georgiev, P; Soldatov, A

Chromatin Reorganization during Myoblast Differentiation Involves the Caspase-Dependent Removal of SATB2

CELLS

IF5.2

2022-03-11

OAAI

Bell, Ryan A., V; Al-Khalaf, Mohammad H.; Brunette, Steve; Alsowaida, Dalal; Chu, Alphonse; Bandukwala, Hina; Dechant, Georg; Apostolova, Galina; Dilworth, F. Jeffrey; Megeney, Lynn A.

A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes 快速肌球蛋白超级增强剂通过与肌球蛋白基因的竞争性相互作用来决定肌纤维表型

NATURE COMMUNICATIONS

IF15.7

2022-02-24

OAAI

Dos Santos, Matthieu; Backer, Stephanie; Aurade, Frederic; Wong, Matthew Man-Kin; Wurmser, Maud; Pierre, Remi; Langa, Francina; Do Cruzeiro, Marcio; Schmitt, Alain; Concordet, Jean-Paul; Sotiropoulos, Athanassia; Jeffrey Dilworth, F.; Noordermeer, Daan; Relaix, Frederic; Sakakibara, Iori; Maire, Pascal

The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation

NUCLEIC ACIDS RESEARCH

IF13.1

2021-07-21

OAAI

Sharma, Tapan; Robinson, Daniel C. L.; Witwicka, Hanna; Dilworth, F. Jeffrey; Imbalzano, Anthony N.

HIRA stabilizes skeletal muscle lineage identity

NATURE COMMUNICATIONS

IF15.7

2021-06-08

OAAI

Esteves de Lima, Joana; Bou Akar, Reem; Machado, Leo; Li, Yuefeng; Drayton-Libotte, Bernadette; Dilworth, F. Jeffrey; Relaix, Frederic

Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation

DEVELOPMENTAL CELL

IF8.7

2021-04-01

OAAI

Robinson, Daniel C. L.; Ritso, Morten; Nelson, Geoffrey M.; Mokhtari, Zeinab; Nakka, Kiran; Bandukwala, Hina; Goldman, Seth R.; Park, Peter J.; Mounier, Remi; Chazaud, Benedicte; Brand, Marjorie; Rudnicki, Michael A.; Adelman, Karen; Dilworth, F. Jeffrey

Derivation and Characterization of Immortalized Human Muscle Satellite Cell Clones from Muscular Dystrophy Patients and Healthy Individuals

CELLS

IF5.2

2020-07-26

OAAI

Massenet, Jimmy; Gitiaux, Cyril; Magnan, Melanie; Cuvellier, Sylvain; Hubas, Arnaud; Nusbaum, Patrick; Dilworth, F. Jeffrey; Desguerre, Isabelle; Chazaud, Benedicte

Intron Retained, Transcript Detained: Intron Retention as a Hallmark of the Quiescent Satellite Cell State

DEVELOPMENTAL CELL

IF8.7

2020-06-01

OAAI

Nakka, Kiran; Kovac, Radmila; Wong, Matthew Man-Kin; Dilworth, F. Jeffrey

Dysregulated expression of monoacylglycerol lipase is a marker for anti-diabetic drug metformin-targeted therapy to correct impaired neurogenesis and spatial memory in Alzheimer's disease

THERANOSTICS

IF13.3

2020-01-01

OAAI

Syal, Charvi; Kosaraju, Jayasankar; Hamilton, Laura; Aumont, Anne; Chu, Alphonse; Sarma, Sailendra Nath; Thomas, Jacob; Seegobin, Matthew; Dilworth, F. Jeffrey; He, Ling; Wondisford, Fredric E.; Zimmermann, Robert; Parent, Martin; Fernandes, Karl; Wang, Jing

The exosome-mediated autocrine and paracrine actions of plasma gelsolin in ovarian cancer chemoresistance

ONCOGENE

IF7.3

2019-11-07

104

OAAI

Asare-Werehene, Meshach; Nakka, Kiran; Reunov, Arkadiy; Chiu, Chen-Tzu; Lee, Wei-Ting; Abedini, Mohammad R.; Wang, Pei-Wen; Shieh, Dar-Bin; Dilworth, F. Jeffrey; Carmona, Euridice; Le, Tien; Mes-Masson, Anne-Marie; Burger, Dylan; Tsang, Benjamin K.

A chemical toolbox for the study of bromodomains and epigenetic signaling

NATURE COMMUNICATIONS

IF15.7

2019-04-23

OAAI

Wu, Qin; Heidenreich, David; Zhou, Stanley; Ackloo, Suzanne; Kraemer, Andreas; Nakka, Kiran; Lima-Fernandes, Evelyne; Deblois, Genevieve; Duan, Shili; Vellanki, Ravi N.; Li, Fengling; Vedadi, Masoud; Dilworth, Jeffrey; Lupien, Mathieu; Brennan, Paul E.; Arrowsmith, Cheryl H.; Mueller, Susanne; Fedorov, Oleg; Filippakopoulos, Panagis; Knapp, Stefan

Polycomb/Trithorax Antagonism: Cellular Memory in Stem Cell Fate and Function

CELL STEM CELL

IF20.4

2019-04-01

OAAI

Brand, Marjorie; Nakka, Kiran; Zhu, Jiayu; Dilworth, F. Jeffrey

Targeting the MTF2-MDM2 Axis Sensitizes Refractory Acute Myeloid Leukemia to Chemotherapy 靶向MTF2-MDM2轴使难治性急性髓系白血病对化疗敏感

CANCER DISCOVERY

IF33.3

2018-11-01

OAAI

Maganti, Harinad B.; Jrade, Hani; Cafariello, Christopher; Rothberg, Janet L. Manias; Porter, Christopher J.; Yockell-Lelievre, Julien; Battaion, Hannah L.; Khan, Safwat T.; Howard, Joel P.; Li, Yuefeng; Grzybowski, Adrian T.; Sabri, Elham; Ruthenburg, Alexander J.; Dilworth, F. Jeffrey; Perkins, Theodore J.; Sabloff, Mitchell; Ito, Caryn Y.; Stanford, William L.

研究方向