Tohru Itoh - Publications, H-index & Citations

Tohru Itoh

University of Tokyo

39H指数

111论文数

5.4K被引数

收录论文 43

发表时间

Development of a high throughput system to screen compounds that revert the activated hepatic stellate cells to a quiescent-like state

SCIENTIFIC REPORTS

IF3.9

2024-04-12

OAAI

Nakano, Yasuhiro; Saijou, Eiko; Itoh, Tohru; Tanaka, Minoru; Miyajima, Atsushi; Kido, Taketomo

Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis

INFLAMMATION AND REGENERATION

IF6.6

2023-10-09

OAAI

Takeda, Nobutaka; Tsuchiya, Atsunori; Mito, Masaki; Natsui, Kazuki; Natusi, Yui; Koseki, Yohei; Tomiyoshi, Kei; Yamazaki, Fusako; Yoshida, Yuki; Abe, Hiroyuki; Sano, Masayuki; Kido, Taketomo; Yoshioka, Yusuke; Kikuta, Junichi; Itoh, Tohru; Nishimura, Ken; Ishii, Masaru; Ochiya, Takahiro; Miyajima, Atsushi; Terai, Shuji

Definition of the role of tyrosine residues of the common β subunit regulating multiple signaling pathways of granulocyte-macrophage colony-stimulating factor receptor

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Itoh, T; Liu, R; Yokota, T; Arai, K; Watanabe, S

Nrf2 Enhances Cholangiocyte Expansion in Pten-Deficient Livers

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Taguchi, Keiko; Hirano, Ikuo; Itoh, Tohru; Tanaka, Minoru; Miyajima, Atsushi; Suzuki, Akira; Motohashi, Hozumi; Yamamoto, Masayuki

Two distinct Notch signals, Delta-like 4/Notch1 and Jagged-1/Notch2, antagonistically regulate chemical hepatocarcinogenesis in mice

COMMUNICATIONS BIOLOGY

IF5.1

2022-01-21

OAAI

Nakano, Yasuhiro; Nakao, Sachie; Sueoka, Minako; Kasahara, Daigo; Tanno, Yuri; Sumiyoshi, Hideaki; Itoh, Tohru; Miyajima, Atsushi; Hozumi, Katsuto; Inagaki, Yutaka

On the Mechanisms of Biliary Flux

HEPATOLOGY

IF15.8

2021-12-01

OAAI

Vartak, Nachiket; Drasdo, Dirk; Geisler, Fabian; Itoh, Tohru; P.J.Oude Elferink, Ronald; van de Graaf, Stan F. J.; Chiang, John; Keitel, Verena; Trauner, Michael; Jansen, Peter; Hengstler, Jan G.

The truth lies somewhere in the middle: the cells responsible for liver tissue maintenance finally identified

CELL REGENERATION

IF4.7

2021-08-04

OAAI

Itoh, Tohru

Generation of functional liver organoids on combining hepatocytes and cholangiocytes with hepatobiliary connections ex vivo 体外结合肝细胞和胆管细胞与肝胆连接的功能性肝类器官的产生

NATURE COMMUNICATIONS

IF15.7

2021-06-07

OAAI

Tanimizu, Naoki; Ichinohe, Norihisa; Sasaki, Yasushi; Itoh, Tohru; Sudo, Ryo; Yamaguchi, Tomoko; Katsuda, Takeshi; Ninomiya, Takafumi; Tokino, Takashi; Ochiya, Takahiro; Miyajima, Atsushi; Mitaka, Toshihiro

Small extracellular vesicles derived from interferon-γ pre-conditioned mesenchymal stromal cells effectively treat liver fibrosis

NPJ REGENERATIVE MEDICINE

IF6.5

2021-03-30

OAAI

Takeuchi, Suguru; Tsuchiya, Atsunori; Iwasawa, Takahiro; Nojiri, Shunsuke; Watanabe, Takayuki; Ogawa, Masahiro; Yoshida, Tomoaki; Fujiki, Katsunori; Koui, Yuta; Kido, Taketomo; Yoshioka, Yusuke; Fujita, Mayu; Kikuta, Junichi; Itoh, Tohru; Takamura, Masaaki; Shirahige, Katsuhiko; Ishii, Masaru; Ochiya, Takahiro; Miyajima, Atsushi; Terai, Shuji

Multidimensional imaging of liver injury repair in mice reveals fundamental role of the ductular reaction

COMMUNICATIONS BIOLOGY

IF5.1

2020-06-05

OAAI

Kamimoto, Kenji; Nakano, Yasuhiro; Kaneko, Kota; Miyajima, Atsushi; Itoh, Tohru

Filling a gYap in Hepato-Biliary Tissue Integration in Liver Homeostasis and Regeneration

CELL STEM CELL

IF20.4

2019-07-01

OAAI

Itoh, Tohru; Miyajima, Atsushi

Nrf2 Activation Ameliorates Hepatotoxicity Induced by a Heme Synthesis Inhibitor

TOXICOLOGICAL SCIENCES

IF4.1

2018-09-12

OAAI

Taguchi, Keiko; Masui, Saho; Itoh, Tohru; Miyajima, Atsushi; Yamamoto, Masayuki

The transcription factor Klf5 is essential for intrahepatic biliary epithelial tissue remodeling after cholestatic liver injury

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-04-01

OAAI

Okada, Hajime; Yamada, Minami; Kamimoto, Kenji; Kok, Cindy Yuet-Yin; Kaneko, Kota; Ema, Masatsugu; Miyajima, Atsushi; Itoh, Tohru

YAP determines the cell fate of injured mouse hepatocytes in vivo (vol 8, 16017, 2017)

NATURE COMMUNICATIONS

IF15.7

2017-08-07

OAAI

Miyamura, Norio; Hata, Shoji; Itoh, Tohru; Tanaka, Minoru; Nishio, Miki; Itoh, Michiko; Ogawa, Yoshihiro; Terai, Shuji; Sakaida, Isao; Suzuki, Akira; Miyajima, Atsushi; Nishina, Hiroshi

YAP determines the cell fate of injured mouse hepatocytes in vivo

NATURE COMMUNICATIONS

IF15.7

2017-07-06

OAAI

Miyamura, Norio; Hata, Shoji; Itoh, Tohru; Tanaka, Minoru; Nishio, Miki; Itoh, Michiko; Ogawa, Yoshihiro; Terai, Shuji; Sakaida, Isao; Suzuki, Akira; Miyajima, Atsushi; Nishina, Hiroshi

Portal Fibroblasts Marked by the Surface Antigen Thy1 Contribute to Fibrosis in Mouse Models of Cholestatic Liver Injury

HEPATOLOGY COMMUNICATIONS

IF4.6

2017-03-22

OAAI

Katsumata, Len William; Miyajima, Atsushi; Itoh, Tohru

Heterogeneity and stochastic growth regulation of biliary epithelial cells dictate dynamic epithelial tissue remodeling

ELIFE

IF0

2016-07-19

OAAI

Kamimoto, Kenji; Kaneko, Kota; Kok, Cindy Yuet-Yin; Okada, Hajime; Miyajima, Atsushi; Itoh, Tohru

Stem/progenitor cells in liver regeneration

HEPATOLOGY

IF15.8

2016-06-24

OAAI

Itoh, Tohru

Intrahepatic Bile Ducts Are Developed Through Formation of Homogeneous Continuous Luminal Network and Its Dynamic Rearrangement in Mice

HEPATOLOGY

IF15.8

2016-04-04

PREAI

Tanimizu, Naoki; Kaneko, Kota; Itoh, Tohru; Ichinohe, Norihisa; Ishii, Masayuki; Mizuguchi, Toru; Hirata, Koichi; Miyajima, Atsushi; Mitaka, Toshihiro

Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice YAP1/TAZ和tgf-β 信号失调介导Mob1a/1b缺陷小鼠肝癌发生

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-12-22

178

OAAI

Nishio, Miki; Sugimachi, Keishi; Goto, Hiroki; Wang, Jia; Morikawa, Takumi; Miyachi, Yosuke; Takano, Yusuke; Hikasa, Hiroki; Itoh, Tohru; Suzuki, Satoshi O.; Kurihara, Hiroki; Aishima, Shinichi; Leask, Andrew; Sasaki, Takehiko; Nakano, Toru; Nishina, Hiroshi; Nishikawa, Yuji; Sekido, Yoshitaka; Nakao, Kazuwa; Shin-ya, Kazuo; Mimori, Koshi; Suzuki, Akira

研究方向