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Directed Evolution of AAV9 for Efficient Gene Expression in Cardiomyocytes In Vitro and In Vivo AAV9的定向进化以实现体外和体内心肌细胞的高效基因表达 Huettermann, Leonard; Schroeder, Lena C.; Shetty, Prithviraj M. V.; Jonker, Timo; Hille, Susanne S.; Remes, Anca Kliesow; Matzen, Andrea; Boender, Arie R.; Grimm, Dirk; Frank, Derk; Boink, Gerard J. J.; Eschenhagen, Thomas; Schade, Dennis; Mueller, Oliver J. 分享 收藏
Addressing the Intracellular Vestibule of the Plasmodial Lactate Transporter PfFNT by p-Substituted Inhibitors Amplifies In Vitro Activity Nerlich, Cornelius; Tiedjens, Finn; Hertel, Robin; Henke, Bjoern; Haeuer, Susan; Panitzsch, Lea S.; Hansen, Kerrin; Franck, Ole; Mete, Antonio; Leroy, Didier; Schade, Dennis; Peifer, Christian; Hannus, Stefan; Becker, Frank; Wittlin, Sergio; Spielmann, Tobias; Beitz, Eric 分享 收藏
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The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation Flegel, Jana; Shaaban, Saad; Jia, Zhi Jun; Schulte, Britta; Lian, Yilong; Krzyzanowski, Adrian; Metz, Malte; Schneidewind, Tabea; Wesseler, Fabian; Flegel, Anke; Reich, Alisa; Brause, Alexandra; Xue, Gang; Zhang, Minghao; Doetsch, Lara; Stender, Isabelle D.; Hoffmann, Jan-Erik; Scheel, Rebecca; Janning, Petra; Rastinejad, Fraydoon; Schade, Dennis; Strohmann, Carsten; Antonchick, Andrey P.; Sievers, Sonja; Moura-Alves, Pedro; Ziegler, Slava; Waldmann, Herbert 分享 收藏
Phenotypic Discovery of Triazolo[1,5-c]quinazolines as a First-In- Class Bone Morphogenetic Protein Amplifier Chemotype Wesseler, Fabian; Lohmann, Stefan; Riege, Daniel; Halver, Jonas; Roth, Aileen; Pichlo, Christian; Weber, Sabrina; Takamiya, Masanari; Mueller, Eva; Ketzel, Jana; Flegel, Jana; Gihring, Adrian; Rastegar, Sepand; Bertrand, Jessica; Baumann, Ulrich; Knippschild, Uwe; Peifer, Christian; Sievers, Sonja; Waldmann, Herbert; Schade, Dennis 分享 收藏
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Probing Embryonic Development Enables the Discovery of Unique Small-Molecule Bone Morphogenetic Protein Potentiators Wesseler, Fabian; Riege, Daniel; Puthanveedu, Mahesh; Halver, Jonas; Mueller, Eva; Bertrand, Jessica; Antonchick, Andrey P.; Sievers, Sonja; Waldmann, Herbert; Schade, Dennis 分享 收藏
High-Throughput Screening Platform in Postnatal Heart Cells and Chemical Probe Toolbox to Assess Cardiomyocyte Proliferation Garcia, Carmen Carrillo; Becker, Cora; Forster, Michael; Lohmann, Stefan; Freitag, Patricia; Laufer, Stefan; Sievers, Sonja; Fleischmann, Bernd K.; Hesse, Michael; Schade, Dennis 分享 收藏
Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness Cheng, Jiongjia; Tsuda, Masanao; Okolotowicz, Karl; Dwyer, Mary; Bushway, Paul J.; Colas, Alexandre R.; Lancman, Joseph J.; Schade, Dennis; Perea-Gil, Isaac; Bruyneel, Arne A. N.; Lee, Jaechol; Vadgama, Nirmal; Quach, Justine; McKeithan, Wesley L.; Biechele, Travis L.; Wu, Joseph C.; Moon, Randall T.; Dong, P. Duc Si; Karakikes, Ioannis; Cashman, John R.; Mercola, Mark 分享 收藏
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A protein tertiary structure mimetic modulator of the Hippo signalling pathway Adihou, Helene; Gopalakrishnan, Ranganath; Foerster, Tim; Gueret, Stephanie M.; Gasper, Raphael; Geschwindner, Stefan; Garcia, Carmen Carrillo; Karatas, Hacer; Pobbati, Ajaybabu, V; Vazquez-Chantada, Mercedes; Davey, Paul; Wassvik, Carola M.; Pang, Jeremy Kah Sheng; Soh, Boon Seng; Hong, Wanjin; Chiarparin, Elisabetta; Schade, Dennis; Plowright, Alleyn T.; Valeur, Eric; Lemurell, Malin; Grossmann, Tom N.; Waldmann, Herbert 分享 收藏
Discovery of N-(4-Aminobutyl)-N′-(2-methoxyethyl)guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dirnethylarginine Dinnethylaminohydrolase-1 (hDDAH-1) Lunk, Ina; Litty, Felix-Alexander; Hennig, Sven; Vetter, Ingrid R.; Kotthaus, Juerke; Altmann, Karin S.; Ott, Gudrun; Havemeyer, Antje; Garcia, Carmen Carrillo; Clement, Bernd; Schade, Dennis 分享 收藏
Differentiation of cardiomyocytes and generation of human engineered heart tissue (vol 12, pg 1177, 2017) Breckwoldt, Kaja; Breniere-Letuffe, David; Mannhardt, Ingra; Schulze, Thomas; Ulmer, Barbel; Werner, Tessa; Benzin, Anika; Klampe, Birgit; Reinsch, Marina C.; Laufer, Sandra; Shibamiya, Aya; Prondzynski, Maksymilian; Mearini, Giulia; Schade, Dennis; Fuchs, Sigrid; Neuber, Christiane; Kramer, Elisabeth; Saleem, Umber; Schulze, Mirja L.; Rodriguez, Marita L.; Eschenhagen, Thomas; Hansen, Arne 分享 收藏
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Toward Second-Generation Cardiomyogenic and Anti-cardiofibrotic 1,4-Dihydropyridine-Class TGFβ Inhibitors Laengle, Daniel; Werner, Tessa R.; Wesseler, Fabian; Reckzeh, Elena; Schaumann, Niklas; Drowley, Lauren; Polla, Magnus; Plowright, Alleyn T.; Hirt, Marc N.; Eschenhagen, Thomas; Schade, Dennis 分享 收藏
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Combined Proteomic and In Silico Target Identification Reveal a Role for 5-Lipoxygenase in Developmental Signaling Pathways 结合蛋白质组学和计算机目标鉴定揭示了5-脂氧合酶在发育信号通路中的作用 Brand, Silke; Roy, Sayantani; Schroeder, Peter; Rathmer, Bernd; Roos, Jessica; Kapoor, Shobhna; Patil, Sumersing; Pommerenke, Claudia; Maier, Thorsten; Janning, Petra; Eberth, Sonja; Steinhilber, Dieter; Schade, Dennis; Schneider, Gisbert; Kumar, Kamal; Ziegler, Slava; Waldmann, Herbert 分享 收藏
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