Pei‐Chi Wei - Publications, H-index & Citations

Pei‐Chi Wei

german cancer research center

19H指数

36论文数

1.7K被引数

收录论文 24

发表时间

Recurrent DNA break clusters drive replication-stress-induced copy number variants and genome diversification DNA断裂簇的复发驱动复制应激诱导的拷贝数变异和基因组多样化

Nature Communications

IF15.7

2026-04-20

OAAI

Lorenzo Corazzi; Alex Ing; Eva Benito; Marco Raffaele Cosenza; Patrick Hasenfeld; Thomas Weber; Anna J. M. Marx; Vivien S. Ionasz; Nathan Trausch; Sarah Benedetto; Giulia Di Muzio; Boyu Ding; Jana Berlanda; Marco Giaisi; Nina Claudino; Thomas Höfer; Jan O. Korbel; Pei-Chi Wei

Breaking the script: transcriptional addiction as a driver of genome instability in cancer 打破脚本：转录依赖性作为癌症中基因组不稳定性的驱动因素

Trends in Genetics

IF16.3

2025-11-20

PREAI

Osama Hidmi; Pei-Chi Wei; Rami I. Aqeilan

Linear interaction between replication and transcription shapes DNA break dynamics at recurrent DNA break Clusters

NATURE COMMUNICATIONS

IF15.7

2024-04-27

OAAI

Corazzi, Lorenzo; Ionasz, Vivien S.; Andrejev, Sergej; Wang, Li-Chin; Vouzas, Athanasios; Giaisi, Marco; Di Muzio, Giulia; Ding, Boyu; Marx, Anna J. M.; Henkenjohann, Jonas; Allers, Michael M.; Gilbert, David M.; Wei, Pei-Chi

Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model

NEURO-ONCOLOGY

IF13.4

2021-05-28

OAAI

Simovic, Milena; Bolkestein, Michiel; Moustafa, Mahmoud; Wong, John K. L.; Koerber, Verena; Benedetto, Sarah; Khalid, Umar; Schreiber, Hannah Sophia; Jugold, Manfred; Korshunov, Andrey; Huebschmann, Daniel; Mack, Norman; Brons, Stephan; Wei, Pei-Chi; Breckwoldt, Michael O.; Heiland, Sabine; Bendszus, Martin; Debus, Jurgen; Hoefer, Thomas; Zapatka, Marc; Kool, Marcel; Pfister, Stefan M.; Abdollahi, Amir; Ernst, Aurelie

Redox sensor NPGPx restrains ZAP70 activity and modulates T cell homeostasi

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2021-03-01

OAAI

Su, Fang-Yi; Huang, Shih-Chia; Wei, Pei-Chi; Hsu, Pang-Hung; Li, Ju-Pi; Su, Li-Wen; Hsieh, Yung-Lin; Hu, Chun-Mei; Hsu, Jye-Lin; Yang, Cheng-Yuan; Chung, Chen-Yen; Shew, Jin-Yuh; Lan, Joung-Liang; Sytwu, Huey-Kang; Lee, Eva Y-Hp; Lee, Wen-Hwa

Induction of recurrent break cluster genes in neural progenitor cells differentiated from embryonic stem cells in culture 从培养的胚胎干细胞分化的神经祖细胞中诱导复发性断裂簇基因

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-04-24

OAAI

Tena, Aseda; Zhang, Yuxiang; Kyritsis, Nia; Devorak, Anne; Zurita, Jeffrey; Wei, Pei-Chi; Alt, Frederick W.

Increased Neural Progenitor Proliferation in a hiPSC Model of Autism Induces Replication Stress-Associated Genome Instability 自闭症hiPSC模型中神经祖细胞增殖增加诱导复制应激相关的基因组不稳定性

CELL STEM CELL

IF20.4

2020-02-01

OAAI

Wang, Meiyan; Wei, Pei-Chi; Lim, Christina K.; Gallina, Iryna S.; Marshall, Sara; Marchetto, Maria C.; Alt, Frederick W.; Gage, Fred H.

Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Ratnaparkhe, Manasi; Wong, John K.; Wei, Pei-Chi; Hlevnjak, Mario; Kolb, Thorsten; Simovic, Milena; Haag, Daniel; Paul, Yashna; Devens, Frauke; Northcott, Paul; Jones, David T.; Kool, Marcel; Jauch, Anna; Pastorczak, Agata; Mlynarski, Wojciech; Korshunov, Andrey; Kumar, Rajiv; Downing, Susanna M.; Pfister, Stefan M.; Zapatka, Marc; McKinnon, Peter J.; Alt, Frederick W.; Lichter, Peter; Ernst, Aurelie

Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors

NATURE COMMUNICATIONS

IF15.7

2018-11-12

OAAI

Ratnaparkhe, Manasi; Wong, John K. L.; Wei, Pei-Chi; Hlevnjak, Mario; Kolb, Thorsten; Simovic, Milena; Haag, Daniel; Paul, Yashna; Devens, Frauke; Northcott, Paul; Jones, David T. W.; Kool, Marcel; Jauch, Anna; Pastorczak, Agata; Mlynarski, Wojciech; Korshunov, Andrey; Kumar, Rajiv; Downing, Susanna M.; Pfister, Stefan M.; Zapatka, Marc; McKinnon, Peter J.; Alt, Frederick W.; Lichter, Peter; Ernst, Aurelie

Kinase-dependent structural role of DNA-PKcs during immunoglobulin class switch recombination

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-08-02

OAAI

Crowe, Jennifer L.; Shao, Zhengping; Wang, Xiaobin S.; Wei, Pei-Chi; Jiang, Wenxia; Lee, Brian J.; Estes, Verna M.; Alt, Frederick W.; Zha, Shan

Inactivation of factors of DNA double-strand break repair by homologous recombination or non-homologous end-joining leads to frequent catastrophic genomic events in murine and human tumors

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Ratnaparkhe, Manasi; Wong, John; Wei, Pei-Chi; Hlevnjak, Mario; Northcott, Paul; Jones, David T.; Kool, Marcel; Jauch, Anna; Pastorczak, Agata; Korshunov, Andrey; Kumar, Rajiv; Downing, Susanna M.; Pfister, Stefan M.; Zapatka, Marc; McKinnon, Peter J.; Alt, Frederick W.; Lichter, Peter; Ernst, Aurelie

Three classes of recurrent DNA break clusters in brain progenitors identified by 3D proximity-based break joining assay

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-02-05

OAAI

Wei, Pei-Chi; Lee, Cheng-Sheng; Du, Zhou; Schwer, Bjoern; Zhang, Yuxiang; Kao, Jennifer; Zurita, Jeffrey; Alt, Frederick W.

DNA double-strand break response factors influence end-joining features of IgH class switch and general translocation junctions

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-01-08

OAAI

Panchaksharia, Rohit A.; Zhang, Xuefei; Kumar, Vipul; Du, Zhou; Wei, Pei-Chi; Kao, Jennifer; Dong, Junchao; Alt, Frederick W.

TGF-β1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up-regulation of IL-17RB

EMBO MOLECULAR MEDICINE

IF8.3

2017-10-09

OAAI

Huang, Shih-Chia; Wei, Pei-Chi; Hwang-Verslues, Wendy W.; Kuo, Wen-Hung; Jeng, Yung-Ming; Hu, Chun-Mei; Shew, Jin-Yuh; Huang, Chiun-Sheng; Chang, King-Jen; Lee, Eva Y-H P.; Lee, Wen-Hwa

Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells 转录相关过程导致神经干/祖细胞中的DNA双链断裂和易位

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-02-12

OAAI

Schwer, Bjoern; Wei, Pei-Chi; Chang, Amelia N.; Kao, Jennifer; Du, Zhou; Meyers, Robin M.; Alt, Frederick W.

Targeting IL-17B-IL-17RB signaling with an anti-IL-17RB antibody blocks pancreatic cancer metastasis by silencing multiple chemokines

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2015-03-02

138

OAAI

Wu, Heng-Hsiung; Hwang-Verslues, Wendy W.; Lee, Wen-Hsin; Huang, Chun-Kai; Wei, Pei-Chi; Chen, Chia-Lin; Shew, Jin-Yuh; Lee, Eva Y. -H. P.; Jeng, Yung-Ming; Tien, Yu-Wen; Ma, Che; Lee, Wen-Hwa

Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human

EMBO MOLECULAR MEDICINE

IF8.3

2013-07-04

OAAI

Chang, Yi-Cheng; Yu, Yu-Hsiang; Shew, Jin-Yuh; Lee, Wei-Jei; Hwang, Juey-Jen; Chen, Yen-Hui; Chen, Yet-Ran; Wei, Pei-Chi; Chuang, Lee-Ming; Lee, Wen-Hwa

A cis-element with mixed G-quadruplex structure of NPGPx promoter is essential for nucleolin-mediated transactivation on non-targeting siRNA stress

NUCLEIC ACIDS RESEARCH

IF13.1

2012-12-14

OAAI

Wei, Pei-Chi; Wang, Zi-Fu; Lo, Wen-Ting; Su, Mei-I; Shew, Jin-Yuh; Chang, Ta-Chau; Lee, Wen-Hwa

Loss of the Oxidative Stress Sensor NPGPx Compromises GRP78 Chaperone Activity and Induces Systemic Disease

MOLECULAR CELL

IF16.6

2012-12-01

128

OAAI

Wei, Pei-Chi; Hsieh, Yi-Hsuan; Su, Mei-I.; Jiang, Xianzhi; Hsu, Pang-Hung; Lo, Wen-Ting; Weng, Jui-Yun; Jeng, Yung-Ming; Wang, Ju-Ming; Chen, Phang-Iang; Chang, Yi-Cheng; Lee, Kuo-Fen; Tsai, Ming-Daw; Shew, Jin-Yuh; Lee, Wen-Hwa

Non-targeting siRNA induces NPGPx expression to cooperate with exoribonuclease XRN2 for releasing the stress

CANCER RESEARCH

IF16.6

2012-04-01

PREAI

Wei, Pei-Chi

研究方向