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Design and Mechanistic Analysis of a Potent Bivalent Inhibitor of Transthyretin Amyloid Fibrillogenesis 设计和机制分析：一种强效的双价转甲状腺素蛋白淀粉样纤维形成抑制剂 Mangione, P. Patrizia; Verona, Guglielmo; Cantarutti, Cristina; Nocerino, Paola; Mimmi, Maria Chiara; Swain, Christopher J.; Canetti, Diana; Giorgetti, Sofia; Uings, Iain; Gillmore, Julian D.; Taylor, Graham W.; Pepys, Mark B.; Bellotti, Vittorio; Corazza, Alessandra 分享 收藏
Oxidative conversion of transthyretin in formalin-fixed clinical amyloid samples results in the formation of the His90Asp and His90Asn variants Raheja, Simran; Verona, Guglielmo; Florent, Paolo; Rendell, Nigel B.; Nocerino, Paola; Ellemerich, Stephan; Fernandes, Raizel; Botcher, Nicola; Rowczenio, Dorota; Gilbertson, Janet A.; Simons, J. Paul; Gillmore, Julian D.; Bellotti, Vittorio; Taylor, Graham W.; Canetti, Diana 分享 收藏
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Amyloid Formation by Globular Proteins: The Need to Narrow the Gap Between in Vitro and in Vivo Mechanisms Faravelli, Giulia; Mondani, Valentina; Mangione, P. Patrizia; Raimondi, Sara; Marchese, Loredana; Lavatelli, Francesca; Stoppini, Monica; Corazza, Alessandra; Canetti, Diana; Verona, Guglielmo; Obici, Laura; Taylor, Graham W.; Gillmore, Julian D.; Giorgetti, Sofia; Bellotti, Vittorio 分享 收藏
Plasmin activity promotes amyloid deposition in a transgenic model of human transthyretin amyloidosis Slamova, Ivana; Adib, Rozita; Ellmerich, Stephan; Golos, Michal R.; Gilbertson, Janet A.; Botcher, Nicola; Canetti, Diana; Taylor, Graham W.; Rendell, Nigel; Tennent, Glenys A.; Verona, Guglielmo; Porcari, Riccardo; Mangione, P. Patrizia; Gillmore, Julian D.; Pepys, Mark B.; Bellotti, Vittorio; Hawkins, Philip N.; Al-Shawi, Raya; Simons, J. Paul 分享 收藏
Dementia in the older population is associated with neocortex content of serum amyloid P component Ellmerich, Stephan; Taylor, Graham W.; Richardson, Connor D.; Minett, Thais; Schmidt, Amand Floriaan; Brayne, Carol; Matthews, Fiona E.; Ince, Paul G.; Wharton, Stephen B.; Pepys, Mark B. 分享 收藏
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Clinical ApoA-IV amyloid is associated with fibrillogenic signal sequence Canetti, Diana; Nocerino, Paola; Rendell, Nigel B.; Botcher, Nicola; Gilbertson, Janet A.; Blanco, Angel; Rowczenio, Dorota; Morelli, Alessandra; Mangione, P. Patrizia; Corazza, Alessandra; Verona, Guglielmo; Giorgetti, Sofia; Marchese, Loredana; Westermark, Per; Hawkins, Philip N.; Gillmore, Julian D.; Bellotti, Vittorio; Taylor, Graham W. 分享 收藏
Clinical Amyloid Typing by Proteomics: Performance Evaluation and Data Sharing between Two Centres Canetti, Diana; Brambilla, Francesca; Rendell, Nigel B.; Nocerino, Paola; Gilbertson, Janet A.; Di Silvestre, Dario; Bergamaschi, Andrea; Lavatelli, Francesca; Merlini, Giampaolo; Gillmore, Julian D.; Bellotti, Vittorio; Mauri, Pierluigi; Taylor, Graham W. 分享 收藏
Comparative study of the stabilities of syntheticin vitroand naturalex vivotransthyretin amyloid fibrils Raimondi, Sara; Mangione, P. Patrizia; Verona, Guglielmo; Canetti, Diana; Nocerino, Paola; Marchese, Loredana; Piccarducci, Rebecca; Mondani, Valentina; Faravelli, Giulia; Taylor, Graham W.; Gillmore, Julian D.; Corazza, Alessandra; Pepys, Mark B.; Giorgetti, Sofia; Bellotti, Vittorio 分享 收藏
Lysozyme amyloid: evidence for the W64R variant by proteomics in the absence of the wild type protein Moura, Alexandra; Nocerino, Paola; Gilbertson, Janet A.; Rendell, Nigel B.; Mangione, P. Patrizia; Verona, Guglielmo; Rowczenio, Dorota; Gillmore, Julian D.; Taylor, Graham W.; Bellotti, Vittorio; Canetti, Diana 分享 收藏
Binding of Monovalent and Bivalent Ligands by Transthyretin Causes Different Short-and Long-Distance Conformational Changes Corazza, Alessandra; Verona, Guglielmo; Waudby, Christopher A.; Mangione, Patrizia; Bingham, Ryan; Uings, Iain; Canetti, Diana; Nocerino, Paola; Taylor, Graham W.; Pepys, Mark B.; Christodoulou, John; Bellotti, Vittorio 分享 收藏
Proteomic Analysis for the Diagnosis of Fibrinogen Aα-chain Amyloidosis Taylor, Graham W.; Gilbertson, Janet A.; Sayed, Rabya; Blanco, Angel; Rendell, Nigel B.; Rowczenio, Dorota; Rezk, Tamer; Mangione, P. Patrizia; Canetti, Diana; Bass, Paul; Hawkins, Philip N.; Gillmore, Julian D. 分享 收藏
The complementary role of histology and proteomics for diagnosis and typing of systemic amyloidosis Rezk, Tamer; Gilbertson, Janet A.; Mangione, P. Patrizia; Rowczenio, Dorota; Rendell, Nigel B.; Canetti, Diana; Lachmann, Helen J.; Wechalekar, Ashutosh D.; Bass, Paul; Hawkins, Philip N.; Bellotti, Vittorio; Taylor, Graham W.; Gillmore, Julian D. 分享 收藏
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Plasminogen activation triggers transthyretin amyloidogenesis in vitro Mangione, P. Patrizia; Verona, Guglielmo; Corazza, Alessandra; Marcoux, Julien; Canetti, Diana; Giorgetti, Sofia; Raimondi, Sara; Stoppini, Monica; Esposito, Marilena; Relini, Annalisa; Canale, Claudio; Valli, Maurizia; Marchese, Loredana; Faravelli, Giulia; Obici, Laura; Hawkins, Philip N.; Taylor, Graham W.; Gillmore, Julian D.; Pepys, Mark B.; Bellotti, Vittorio 分享 收藏
Misidentification of transthyretin and immunoglobulin variants by proteomics due to methyl lysine formation in formalin-fixed paraffin-embedded amyloid tissue Canetti, Diana; Rendell, Nigel Brian; Di Vagno, Lucia; Gilbertson, Janet A.; Rowczenio, Dorota; Rezk, Tamar; Gillmore, Julian D.; Hawkins, Phillip N.; Verona, Guglielmo; Mangione, Palma Patrizia; Giorgetti, Sofia; Mauri, Pierluigi; Motta, Sara; De Palma, Antonella; Bellotti, Vittorio; Taylor, Graham W. 分享 收藏
Renal Amyloidosis Associated With 5 Novel Variants in the Fibrinogen A Alpha Chain Protein Rowczenio, Dorota; Stensland, Maria; de Souza, Gustavo A.; Strom, Erik H.; Gilbertson, Janet A.; Taylor, Graham; Rendell, Nigel; Minogue, Shane; Efebera, Yvonne A.; Lachmann, Helen J.; Wechalekar, Ashutosh D.; Hawkins, Philip N.; Heimdal, Ketil R.; Selvig, Kristian; Laegreid, Inger K.; Demoulin, Nathalie; Aydin, Selda; Gillmore, Julian D.; Wien, Tale N. 分享 收藏
A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo Raimondi, Sara; Porcari, Riccardo; Mangione, P. Patrizia; Verona, Guglielmo; Marcoux, Julien; Giorgetti, Sofia; Taylor, Graham W.; Ellmerich, Stephan; Ballico, Maurizio; Zanini, Stefano; Pardon, Els; Al-Shawi, Raya; Simons, J. Paul; Corazza, Alessandra; Fogolari, Federico; Leri, Manuela; Stefani, Massimo; Bucciantini, Monica; Gillmore, Julian D.; Hawkins, Philip N.; Valli, Maurizia; Stoppini, Monica; Robinson, Carol V.; Steyaert, Jan; Esposito, Gennaro; Bellotti, Vittorio 分享 收藏
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