Ilia G. Denisov - Publications, H-index & Citations

Ilia G. Denisov

university of illinois

43H指数

118论文数

9.3K被引数

收录论文 46

发表时间

Lipid Dependence of CYP3A4 Activity in Nanodiscs

Biology

IF3.5

2026-01-19

OAAI

Ilia G. Denisov; Yelena V. Grinkova; Stephen G. Sligar

Mechanistic and spectroscopic characterization of human CYP17A1 in Nanodiscs 机制与光谱学表征纳米盘中的人类CYP17A1

Journal of Inorganic Biochemistry

IF3.2

2026-01-07

OAAI

Ilia G. Denisov; Yilin Liu; Piotr J. Mak; Stephen G. Sligar

Optical annealing of peroxo-ferric intermediates in CYP17A1 and product formation.

JOURNAL OF INORGANIC BIOCHEMISTRY

IF3.2

2024-11-01

PREAI

Denisov, Ilia G.; Grinkova, Yelena V.; Sligar, Stephen G.

Nanodiscs for the study of membrane proteins

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2024-08-01

PREAI

Denisov, Ilia G.; Sligar, Stephen G.

More about properties of Morse oscillator

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

IF4.6

2021-12-01

PREAI

Denisov, G. S.; Denisov, I. G.

Substrate-Specific Allosteric Effects on the Enhancement of CYP17A1 Lyase Efficiency by Cytochrome b5

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2021-03-03

OAAI

Liu, Yilin; Denisov, Ilia G.; Sligar, Stephen G.; Kincaid, James R.

Biotransformation of the Mycotoxin Enniatin B1 by CYP P450 3A4 and Potential for Drug-Drug Interactions

METABOLITES

IF3.7

2019-07-27

OAAI

Ivanova, Lada; Denisov, Ilia G.; Grinkova, Yelena, V; Sligar, Stephen G.; Faeste, Christiane K.

Cytochrome b5 enhances androgen synthesis by rapidly reducing the CYP17A1 oxy-complex in the lyase step

FEBS LETTERS

IF3

2018-06-21

OAAI

Duggal, Ruchia; Denisov, Ilia G.; Sligar, Stephen G.

Human Cytochrome CYP17A1: The Structural Basis for Compromised Lyase Activity with 17-Hydroxyprogesterone

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2018-05-15

OAAI

Mak, Piotr J.; Duggal, Ruchia; Denisov, Ilia G.; Gregory, Michael C.; Sligar, Stephen G.; Kincaid, James R.

Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria

CELL CHEMICAL BIOLOGY

IF7.2

2017-10-01

OAAI

Guo, Zhijun; Sevrioukova, Irina F.; Denisov, Ilia G.; Zhang, Xia; Chiu, Ting-Lan; Thomas, Dafydd G.; Hanse, Eric A.; Cuellar, Rebecca A. D.; Grinkova, Yelena V.; Langenfeld, Vanessa Wankhede; Swedien, Daniel S.; Stamschror, Justin D.; Alvarez, Juan; Luna, Fernando; Galvan, Adela; Bae, Young Kyung; Wulfkuhle, Julia D.; Gallagher, Rosa I.; Petricoin, Emanuel F.; Norris, Beverly; Flory, Craig M.; Schumacher, Robert J.; O'Sullivan, M. Gerard; Cao, Qing; Chu, Haitao; Lipscomb, John D.; Atkins, William M.; Gupta, Kalpna; Kelekar, Ameeta; Blair, Ian A.; Capdevila, Jorge H.; Falck, John R.; Sligar, Stephen G.; Poulos, Thomas L.; Georg, Gunda I.; Ambrose, Elizabeth; Potter, David A.

Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria (vol 24, pg 1259, 2017)

CELL CHEMICAL BIOLOGY

IF7.2

2017-10-01

OAAI

Hexyl-benzyl-biguanide (HBB) potently and selectively inhibits CYP3A4 epoxygenase activity and inhibits EET stabilization of mitochondrial respiration in ER+HER2-breast cancer cells, inducing glycolysis and pyruvate biosynthesis

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Guo, Zhijun; Sevrioukova, Irina; Hanse, Eric; Zhang, Xia; Denisov, Ilia; Chiu, Ting-Lan; Cuellar, Rebecca; Torres, Christian; Wulfkuhle, Julia; Petricoin, Emanuel; Cao, Qing; Chu, Haitao; Norris, Beverly; Schumacher, Robert; Kelekar, Ameeta; Blair, Ian; Capdevila, Jorge; Falck, John; Poulos, Thomas; Sligar, Steven; Georg, Gunda; Amin, Elizabeth; Potter, David A.

Nanodiscs for structural and functional studies of membrane proteins

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2016-06-07

423

OAAI

Denisov, Ilia G.; Sligar, Stephen G.

The use of isomeric testosterone dimers to explore allosteric effects in substrate binding to cytochrome P450 CYP3A4

JOURNAL OF INORGANIC BIOCHEMISTRY

IF3.2

2016-05-01

OAAI

Denisov, Ilia G.; Mak, Piotr J.; Grinkova, Yelena V.; Bastien, Dominic; Berube, Gervais; Sligar, Stephen G.; Kincaid, James R.

Unveiling the crucial intermediates in androgen production

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-12-14

OAAI

Mak, Piotr J.; Gregory, Michael C.; Denisov, Ilia G.; Sligar, Stephen G.; Kincaid, James R.

METALLOPROTEINS The long and the short of it

NATURE CHEMISTRY

IF20.2

2015-08-20

PREAI

Denisov, Ilia G.; Sligar, Stephen G.

CYP3A4 epoxygenase activity mediates ER plus mammary tumor growth and angiogenesis, in part, through EET biosynthesis and is inhibited by biguanides

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Guo, Zhijun; Sevrioukova, Irina F.; Hanse, Eric; Denisov, Ilia; Zhang, Xia; Chiu, Ting-Lan; Swedien, Daniel; Stamschror, Justin; Alvarez, Juan; Ortiz, William Marerro; Morgan, Monique; Maher, Michael; Chavez, Kathryn J.; Thomas, Dafydd; Bae, Young Kyung; Henriksen, Jonathan; Norris, Beverly; Schumacher, Robert J.; Wang, Henry; Bliss, Robin; Chu, Haitao; Cuellar, Rebecca; Poulos, Thomas L.; Sligar, Stephen G.; Atkins, William; Schmechel, Stephen; Capdevila, Jorge; Falck, John; Blair, Ian; Jones, Jeffrey P.; Georg, Gunda; Gupta, Kalpna; Kelekar, Ameeta; Amin, Elizabeth; Potter, David A.

Breast cancer inhibition by a novel and potent biguanide, N1-hexyl-N5-benzyl-biguanide

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Guo, Zhijun; Chavez, Kathryn J.; Alvarez, Juan; Zhang, Xia; Norris, Beverly; Maher, Michael; Morgan, Monique; Schumacher, Robert J.; Cuellar, Rebecca; Sevrioukova, Irina F.; Poulos, Thomas L.; Denisov, Ilia; Sligar, Stephen G.; Gupta, Kalpna; Blair, Ian A.; Capdevila, Jorge; Kelekar, Ameeta; Amin, Elizabeth; Georg, Gunda; Potter, David A.

Kinetic Solvent Isotope Effect in Human P450 CYP17A1-Mediated Androgen Formation: Evidence for a Reactive Peroxoanion Intermediate

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2013-10-29

OAAI

Gregory, Michael C.; Denisov, Ilia G.; Grinkova, Yelena V.; Khatri, Yogan; Sligar, Stephen G.

A novel type of allosteric regulation: Functional cooperativity in monomeric proteins

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

IF3

2012-03-01

OAAI

Denisov, Ilia G.; Sligar, Stephen G.

研究方向