未登录 Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function Carter, Edward P.; Yoneten, Kubra K.; Gavara, Nuria; Tyler, Eleanor J.; Gauthier, Valentine; Murray, Elizabeth R.; ten Dijke, Peter; Cameron, Angus J.; Pearce, Oliver; Grose, Richard P. 分享 收藏
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Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion Tomas Bort, Elena; Joseph, Megan D.; Wang, Qiaoying; Carter, Edward P.; Roth, Nicolas J.; Gibson, Jessica; Samadi, Ariana; Kocher, Hemant M.; Simoncelli, Sabrina; McCormick, Peter J.; Grose, Richard P. 分享 收藏
TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression Gibson, Shayin V.; Tomas Bort, Elena; Rodriguez-Fernandez, Lucia; Allen, Michael D.; Gomm, Jennifer J.; Goulding, Iain; Keller, Ulrich Auf Dem; Agnoletto, Andrea; Brisken, Cathrin; Peck, Barrie; Cameron, Angus J.; Marshall, John F.; Jones, J. Louise; Carter, Edward P.; Grose, Richard P. 分享 收藏
Low HER2 expression in normal breast epithelium enables dedifferentiation and malignant transformation via chromatin opening Hayat, Ateequllah; Carter, Edward P.; King, Hamish W.; Ors, Aysegul; Doe, Aaron; Teijeiro, Saul A.; Charrot, Sarah; Godinho, Susana; Cutillas, Pedro; Mohammed, Hisham; Grose, Richard P.; Ficz, Gabriella 分享 收藏
Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1 (Nov, 10.1038/s41388-02202513-5, 2022) Coetzee, Abigail S.; Carter, Edward P.; Rodriguez-Fernandez, Lucia; Heward, James; Wang, Qiaoying; Karim, Saadia A.; Boughetane, Lina; Milton, Christopher; Uyulur, Firat; Morton, Jennifer P.; Kocher, Hemant M.; Grose, Richard P. 分享 收藏
A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase Kuki, Naoki; Walmsley, David L.; Kanai, Kazuo; Takechi, Sho; Yoshida, Masao; Murakami, Ryo; Takano, Kohei; Tominaga, Yuichi; Takahashi, Mizuki; Ito, Shuichiro; Nakao, Naoki; Angove, Hayley; Baker, Lisa M.; Carter, Edward; Dokurno, Pawel; Le Strat, Loic; Macias, Alba T.; Molyneaux, Carrie-Anne; Murray, James B.; Surgenor, Allan E.; Hamada, Tomoaki; Hubbard, Roderick E. 分享 收藏
Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1 Coetzee, Abigail S.; Carter, Edward P.; Rodriguez-Fernandez, Lucia; Heward, James; Wang, Qiaoying; Karim, Saadia A.; Boughetane, Lina; Milton, Christopher; Uyulur, Firat; Morton, Jennifer P.; Kocher, Hemant M.; Grose, Richard P. 分享 收藏
Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion Murray, Elizabeth R.; Menezes, Shinelle; Henry, Jack C.; Williams, Josie L.; Alba-Castellon, Lorena; Baskaran, Priththivika; Quetier, Ivan; Desai, Ami; Marshall, Jacqueline J. T.; Rosewell, Ian; Tatari, Marianthi; Rajeeve, Vinothini; Khan, Faraz; Wang, Jun; Kotantaki, Panoraia; Tyler, Eleanor J.; Singh, Namrata; Reader, Claire S.; Carter, Edward P.; Hodivala-Dilke, Kairbaan; Grose, Richard P.; Kocher, Hemant M.; Gavara, Nuria; Pearce, Oliver; Cutillas, Pedro; Marshall, John F.; Cameron, Angus J. M. 分享 收藏
Elucidating the role of the kinase activity of endothelial cell focal adhesion kinase in angiocrine signalling and tumour growth Newport, Emma; Pedrosa, Ana Rita; Lees, Delphine; Dukinfield, Matthew; Carter, Edward; Gomez-Escudero, Jesus; Casado, Pedro; Rajeeve, Vinothini; Reynolds, Louise E.; Cutillas, Pedro R.; Duffy, Stephen W.; Delgado, Beatriz De Luxan; Hodivala-Dilke, Kairbaan 分享 收藏
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Centrosome amplification mediates small extracellular vesicle secretion via lysosome disruption Adams, Sophie D.; Csere, Judit; D'angelo, Gisela; Carter, Edward P.; Romao, Maryse; Arnandis, Teresa; Dodel, Martin; Kocher, Hemant M.; Grose, Richard; Raposo, Gracca; Mardakheh, Faraz; Godinho, Susana A. 分享 收藏
Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway Wilcz-Villega, Ewa; Carter, Edward; Ironside, Alastair; Xu, Ruoyan; Mataloni, Isabella; Holdsworth, Julie; Jones, William; Bejar, Rocio Moreno; Uhlik, Lukas; Bentham, Robert B.; Godinho, Susana A.; Dalli, Jesmond; Grose, Richard; Szabadkai, Gyorgy; Jones, Louise; Hodivala-Dilke, Kairbaan; Bianchi, Katiuscia 分享 收藏
Tumor Angiogenesis Is Differentially Regulated by Phosphorylation of Endothelial Cell Focal Adhesion Kinase Tyrosines-397 and-861 Pedrosa, Ana-Rita; Bodrug, Natalia; Gomez-Escudero, Jesus; Carter, Edward P.; Reynolds, Louise E.; Georgiou, Paraskivi Natalia; Fernandez, Isabelle; Lees, Delphine M.; Kostourou, Vassiliki; Alexopoulou, Annika N.; Batista, Silvia; Tavora, Bernardo; Serrels, Bryan; Parsons, Maddy; Iskratsch, Thomas; Hodivala-Dilke, Kairbaan M. 分享 收藏
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PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer Fearon, Abbie E.; Carter, Edward P.; Clayton, Natasha S.; Wilkes, Edmund H.; Baker, Ann-Marie; Kapitonova, Ekaterina; Bakhouche, Bakhouche A.; Tanner, Yasmine; Wang, Jun; Gadaleta, Emanuela; Chelala, Claude; Moore, Kate M.; Marshall, John F.; Chupin, Juliette; Schmid, Peter; Jones, J. Louise; Lockley, Michelle; Cutillas, Pedro R.; Grose, Richard P. 分享 收藏
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MEDI1873, a potent, stabilized hexameric agonist of human GITR with regulatory T-cell targeting potential Tigue, Natalie J.; Bamber, Lisa; Andrews, John; Ireland, Samantha; Hair, James; Carter, Edward; Sridharan, Sudharsan; Jovanovic, Jelena; Rees, D. Gareth; Springall, Jeremy S.; Solier, Emilie; Li, Yi-Ming; Chodorge, Matthieu; Perez-Martinez, David; Higazi, Daniel R.; Oberst, Michael; Kennedy, Maureen; Black, Chelsea M.; Yan, Li; Schwickart, Martin; Maguire, Shaun; Cann, Jennifer A.; de Haan, Lolke; Young, Lesley L.; Vaughan, Tristan; Wilkinson, Robert W.; Stewart, Ross 分享 收藏
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