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S

Sini Heinonen

university of helsinki
H指数:28
被引数:2,999

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Decreased degree of adipocyte differentiation in visceral adipose tissue contributes to metabolic dysfunction-associated steatotic liver disease

内脏脂肪组织中脂肪细胞分化程度的降低有助于代谢功能障碍相关的脂肪变性肝病

Nature Communications
IF15.7
2026-06-030
OAAI
Kyla Z. Gelev; Seung Hyuk T. Lee; Marcus Alvarez; Rosellina M. Mancina; Federica Tavaglione; Oveis Jamialahmadi; Umberto Vespasiani-Gentilucci; Asha Kar; Zitian Wang; Dorota Kaminska; Minna U. Kaikkonen; Ville Männistö; Sini Heinonen; Tuure Saarinen; Anne Juuti; Kirsi H. Pietiläinen; Jussi Pihlajamäki; Stefano Romeo; Päivi Pajukanta
Adipose single cell epigenome and transcriptome localize genetic risk for cardiometabolic disease and accelerated aging

脂肪组织单细胞表观基因组与转录组定位心血管代谢疾病及加速衰老的遗传风险

Nature Communications
IF15.7
2026-04-200
OAAI
Seung Hyuk T. Lee; Asha Kar; Kyla Z. Gelev; Zeyuan Johnson Chen; Sankha Subhra Das; Sini Heinonen; Tuure Saarinen; Maija Vaittinen; Dorota Kaminska; Hilkka Peltoniemi; Chongyuan Luo; Anne Juuti; Ville Männistö; Jussi Pihlajamäki; Minna U. Kaikkonen; Kirsi H. Pietiläinen; Brunilda Balliu; Päivi Pajukanta
The effect of obesity and aging on NAD+/Sirtuin metabolism transcription and DNA methylation in subcutaneous adipose tissue of monozygotic twin pairs discordant for BMI

肥胖和衰老对体重指数不一致的单卵双胞胎皮下脂肪组织中NAD+/Sirtuin代谢转录和DNA甲基化的影响

International Journal of Obesity
IF3.8
2026-01-050
OAAI
Helena A. K. Lapatto; Birgitta W. van der Kolk; Maheswary Muniandy; Sini Heinonen; Aino Heikkinen; Marcus Alvarez; Seung Hyuk T. Lee; Riikka Jokinen; Jesper Lundbom; Juho Kuula; Antti Hakkarainen; Per-Henrik Groop; Jaakko Kaprio; Taru Tukiainen; Miina Ollikainen; Päivi Pajukanta; Eija Pirinen; Kirsi H. Pietiläinen
Effects of Whole-Body Cryotherapy Combined With Conventional Obesity Management Versus Obesity Management Alone: A Clinical Trial

全身冷冻疗法结合常规肥胖管理与单独肥胖管理的效果：一项临床 trial

Obesity
IF4.7
2025-09-030
OAAI
Jari E. Karppinen; Laura Suojanen; Sini Heinonen; Sanna Kaye; Birgitta W. van der Kolk; James W. White; Janne Orava; Seung Hyuk T. Lee; Eugené Dillon; Maheswary Muniandy; Aila Rissanen; Carel W. le Roux; Neil Docherty; Päivi Pajukanta; Kirsi A. Virtanen; Kirsi H. Pietiläinen
Single-cell DNA methylome and 3D genome atlas of human subcutaneous adipose tissue

单细胞DNA甲基组和人类皮下脂肪组织3D基因组图谱

Nature Genetics
IF0
2025-08-200
OAAI
Zeyuan Johnson Chen; Sankha Subhra Das; Asha Kar; Seung Hyuk T. Lee; Kevin D. Abuhanna; Marcus Alvarez; Mihir G. Sukhatme; Zitian Wang; Kyla Z. Gelev; Matthew G. Heffel; Yi Zhang; Oren Avram; Elior Rahmani; Sriram Sankararaman; Markku Laakso; Sini Heinonen; Hilkka Peltoniemi; Eran Halperin; Kirsi H. Pietiläinen; Chongyuan Luo; Päivi Pajukanta
An abdominal obesity missense variant in the adipocyte thermogenesis gene TBX15 is implicated in adaptation to cold in Finns
AMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
2024-11-010
OAAI
Deal, Milena; Kar, Asha; Lee, Seung Hyuk T.; Alvarez, Marcus; Rajkumar, Sandhya; Arasu, Uma Thanigai; Kaminska, Dorota; Mannisto, Ville; Heinonen, Sini; van der Kolk, Birgitta W.; Sailakivi, Ulla; Saarinen, Tuure; Juuti, Anne; Pihlajamaki, Jussi; Kaikkonen, Minna U.; Laakso, Markku; Pietilainen, Kirsi H.; Pajukanta, Paivi
Single nucleus RNA-sequencing integrated into risk variant
EBIOMEDICINE
IF10.8
2024-08-013
PRE
Lee, Seung Hyuk T.; Garske, Kristina M.; Arasu, Uma Thanigai; Kar, Asha; Miao, Zong; Alvarez, Marcus; Koka, Amogha; Darci-Maher, Nicholas; Benhammou, Jihane N.; Pan, David Z.; Ord, Tiit; Kaminska, Dorota; Mannisto, Ville; Heinonen, Sini; Wabitsch, Martin; Laakso, Markku; Agopian, Vatche G.; Pisegna, Joseph R.; Pietilainen, Kirsi H.; Pihlajamaki, Jussi; Kaikkonen, Minna U.; Pajukanta, Paeivi
Cell-Type Composition Affects Adipose Gene Expression Associations With Cardiometabolic Traits
DIABETES
IF7.5
2023-08-304
OAAI
Brotman, Sarah M.; Oravilahti, Anniina; Rosen, Jonathan D.; Alvarez, Marcus; Heinonen, Sini; van der Kolk, Birgitta W.; Silva, Lilian Fernandes; Perrin, Hannah J.; Vadlamudi, Swarooparani; Pylant, Cortney; Deochand, Sonia; Basta, Patricia V.; Valone, Jordan M.; Narain, Morgan N.; Stringham, Heather M.; Boehnke, Michael; Kuusisto, Johanna; Love, Michael I.; Pietilainen, Kirsi H.; Pajukanta, Paivi; Laakso, Markku; Mohlke, Karen L.
Impaired Adipocyte SLC7A10 Promotes Lipid Storage in Association With Insulin Resistance and Altered BCAA Metabolism
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
IF5.1
2023-03-145
OA
Jersin, Regine A.; Tallapragada, Divya Sri Priyanka; Skartveit, Linn; Bjune, Mona S.; Muniandy, Maheswary; Lee-Odegard, Sindre; Heinonen, Sini; Alvarez, Marcus; Birkeland, Kare Inge; Drevon, Christian Andre; Pajukanta, Paeivi; McCann, Adrian; Pietilainen, Kirsi H.; Claussnitzer, Melina; Mellgren, Gunnar; Dankel, Simon N.
Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study

烟酰胺核苷改善肌肉线粒体生物合成、卫星细胞分化和肠道微生物群的双生子研究

SCIENCE ADVANCES
IF12.5
2023-01-1348
OAAI
Lapatto, Helena A. K.; Kuusela, Minna; Heikkinen, Aino; Muniandy, Maheswary; van der Kolk, Birgitta W.; Gopalakrishnan, Swetha; Pollanen, Noora; Sandvik, Martin; Schmidt, Mark S.; Heinonen, Sini; Saari, Sina; Kuula, Juho; Hakkarainen, Antti; Tampio, Janne; Saarinen, Tuure; Taskinen, Marja-Riitta; Lundbom, Nina; Groop, Per-Henrik; Tiirola, Marja; Katajisto, Pekka; Lehtonen, Marko; Brenner, Charles; Kaprio, Jaakko; Pekkala, Satu; Ollikainen, Miina; Pietilainen, Kirsi H.; Pirinen, Eija
The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites (vol 3, pg 1633, 2021)
NATURE METABOLISM
IF20.8
2022-02-110
OA
Bean, Camilla; Audano, Matteo; Varanita, Tatiana; Favaretto, Francesca; Medaglia, Marta; Gerdol, Marco; Pernas, Lena; Stasi, Fabio; Giacomello, Marta; Herkenne, Stephanie; Muniandy, Maheswary; Heinonen, Sini; Cazaly, Emma; Ollikainen, Miina; Milan, Gabriella; Pallavicini, Alberto; Pietilainen, Kirsi H.; Vettor, Roberto; Mitro, Nico; Scorrano, Luca
Computational modelling of self-reported dietary carbohydrate intake on glucose concentrations in patients undergoing Roux-en-Y gastric bypass versus one-anastomosis gastric bypass

接受roux-en-y胃旁路术与单吻合术胃旁路术的患者自我报告的饮食碳水化合物摄入量对葡萄糖浓度的计算模型

ANNALS OF MEDICINE
IF4.3
2021-10-298
OAAI
Ashrafi, Reza A.; Ahola, Aila J.; Rosengard-Barlund, Milla; Saarinen, Tuure; Heinonen, Sini; Juuti, Anne; Marttinen, Pekka; Pietilainen, Kirsi H.
Molecular pathways behind acquired obesity: Adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI
CELL REPORTS MEDICINE
IF10.6
2021-04-0141
OAAI
van der Kolk, Birgitta W.; Saari, Sina; Lovric, Alen; Arif, Muhammad; Alvarez, Marcus; Ko, Arthur; Miao, Zong; Sahebekhtiari, Navid; Muniandy, Maheswary; Heinonen, Sini; Oghabian, Ali; Jokinen, Riikka; Jukarainen, Sakari; Hakkarainen, Antti; Lundbom, Jesper; Kuula, Juho; Groop, Per-Henrik; Tukiainen, Taru; Lundbom, Nina; Rissanen, Aila; Kaprio, Jaakko; Williams, Evan G.; Zamboni, Nicola; Mardinoglu, Adil; Pajukanta, Paivi; Pietilainen, Kirsi H.

研究方向

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K
Kirsi H. Pietiläinen
H 指数:77论文数:439被引数:2.7万
M
Maheswary Muniandy
H 指数:14论文数:33被引数:1,298
P
Päivi Pajukanta
H 指数:55论文数:254被引数:1.4万
T
Tuure Saarinen
H 指数:10论文数:33被引数:723
J
Jaakko Kaprio
H 指数:187论文数:2,392被引数:19.4万
N
Nina Lundbom
H 指数:54论文数:194被引数:9,724
M
Marcus Alvarez
H 指数:23论文数:84被引数:5,555
A
Antti Hakkarainen
H 指数:51论文数:248被引数:8,518
A
Aila Rissanen
H 指数:75论文数:307被引数:2.6万
S
Seung Hyuk Lee
H 指数:9论文数:56被引数:392