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P

Pavlo Lutsik

german cancer research center
H指数:26
被引数:3,623

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Recurrent mechanisms of biallelic epigenetic inactivation reveal new putative tumour suppressor genes in prostate cancer

前列腺癌中双等位基因表观遗传失活的复发机制揭示了新的潜在肿瘤抑制基因

Nature Communications
IF15.7
2026-09-090
OAAI
Daria Kiriy; Francesco Favero; Clarissa Gerhäuser; Jessica Heilmann; Pavlo Lutsik; Francisco German Rodriguez Gonzalez; Alessio Locallo; Jakob Schmidt Jespersen; Andreas J. Gruber; Andre V. Olsen; Barbara Hernando; Kevin CL Cheng; Diogo Pellegrina; Geoff Macintyre; G. Steven Bova; Daniel S. Brewer; Robert G. Bristow; Mark N. Brook; Benedikt Brors; Adam Butler; Géraldine Cancel-Tassin; Niall M. Corcoran; Olivier Cussenot; Ros A. Eeles; Abraham Gihawi; Etsehiwot G. Girma; Vincent J. Gnanapragasam; Anis Hamid; Vanessa M. Hayes; Housheng Hansen He; Christopher M. Hovens; Eddie L. Imada; G. Maria Jakobsdottir; Chol-Hee Jung; Francesca Khani; Zsofia Kote-Jarai; Philippe P. Lamy; Gregory Leeman; Massimo Loda; Luigi Marchionni; Ramyar Molania; Anthony T. Papenfuss; Bernard Pope; Lucio R. Queiroz; Tobias Rausch; Brian Robinson; Atef Sahli; Karina D. Sørensen; Sebastian Uhrig; David C. Wedge; Yaobo Xu; Takafumi N. Yamaguchi; Claudio Zanettini; Colin S. Cooper; Thorsten Schlomm; Jüri Reimand; Joachim Weischenfeldt
Integrated signatures define mutational processes in prostate cancer

整合特征定义前列腺癌中的突变过程

Nature
IF48.5
2026-09-090
OAAI
Andreas J. Gruber; André V. Olsen; Barbara Hernando; Kevin C. L. Cheng; Clarissa Gerhäuser; Marina Torres; Francesco Favero; Daria Kiriy; Ángel Fernández-Sanromán; Juan Maria Roldan-Romero; Lucy Barton; Diogo Pellegrina; G. Steven Bova; Daniel S. Brewer; Mark N. Brook; Benedikt Brors; Adam Butler; Géraldine Cancel-Tassin; Niall M. Corcoran; Olivier Cussenot; Abraham Gihawi; Etsehiwot G. Girma; Vincent J. Gnanapragasam; Anis A. Hamid; Vanessa M. Hayes; Housheng Hansen He; Christopher M. Hovens; Eddie L. Imada; G. Maria Jakobsdottir; Chol-Hee Jung; Francesca Khani; Zsofia Kote-Jarai; Philippe Lamy; Gregory Leeman; Massimo Loda; Pavlo Lutsik; Luigi Marchionni; Ramyar Molania; Anthony T. Papenfuss; Bernard Pope; Lucio R. Queiroz; Tobias Rausch; Brian Robinson; Atef Sahli; Karina D. Sørensen; Takafumi N. Yamaguchi; Sebastian Uhrig; Yaobo Xu; Claudio Zanettini; Ronald Simon; Guido Sauter; Ros A. Eeles; Colin S. Cooper; Robert G. Bristow; David C. Wedge; Thorsten Schlomm; Geoff Macintyre; Jüri Reimand; Joachim Weischenfeldt
Correction: GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer

更正：GLYATL1与腔型乳腺癌中的代谢和表观遗传变化以及内分泌耐药性相关

Clinical Epigenetics
IF4.4
2026-07-100
OAAI
Janina Müller; Emre Sofyali; Luisa Schwarzmüller; Yael Aylon; Eviatar Weizman; Lisa Schlicker; Katherine Kelly; Simone Borgoni; Simin Oz; Cole Stocker; Sara Burmester; Angelika Wörner; Sabine Karolus; Birgitta E. Michels; Daniela Heiss; Rainer Will; Veronica Rodrigues de Melo Costa; Pavlo Lutsik; Dieter Weichenhan; Ilse Hofmann; Nishanth Belugali Nataraj; Yosef Yarden; Luca Magnani; Christoph Plass; Almut Schulze; Cindy Körner; Moshe Oren; Stefan Wiemann
Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard

Pipeline Olympics：针对DNA甲基化测序数据，基于实验金标准的可延续性计算工作流基准测试

NUCLEIC ACIDS RESEARCH
IF13.1
2025-10-280
OAAI
Lin, Yu-Yu; Breuer, Kersten; Weichenhan, Dieter; Lafrenz, Pascal; Sarnataro, Antonella; Wilk, Agata; Chepeleva, Maryna; Mucke, Oliver; Schonung, Maximilian; Petermann, Franziska; Kensche, Philip Reiner; Weiser, Lena; Thommen, Frank; Giacomelli, Gideon; Nordstroem, Karl; Gonzalez-Avalos, Edahi; Merkel, Angelika; Kretzmer, Helene; Fischer, Jonas; Kramer, Stephen; Iskar, Murat; Wolf, Stephan; Buchhalter, Ivo; Esteller, Manel; Lawerenz, Christian; Twardziok, Sven; Zapatka, Marc; Hovestadt, Volker; Schlesner, Matthias; Schulz, Marcel H.; Hoffmann, Steve; Gerhauser, Clarissa; Walter, Jorn; Hartmann, Mark; Lipka, Daniel B.; Assenov, Yassen; Bock, Christoph; Plass, Christoph; Toth, Reka; Lutsik, Pavlo
DNA demethylation-mediated downregulation of MNX1 in acute myeloid leukemia

DNA去甲基化介导的MNX1在急性髓系白血病中的下调

Leukemia
IF13.4
2025-07-140
OAAI
Simge Kelekçi; Katherine Kelly; Ashish Goyal; Nick Wehrwein; Anna Riedel; Dieter Weichenhan; Michael Scherer; Birgitta E. Michels; Cindy Körner; Irene Orzella; Mariam Hakobyan; Marion Bähr; Elena Everatt; James Dunford; Daniel B. Lipka; Pavlo Lutsik; Udo Oppermann; Christoph Plass
Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13)

增强子-启动子相互作用的改变导致t(7;12)(q36;p13) 小儿急性髓系白血病MNX1表达

BLOOD ADVANCES
IF7.1
2024-09-271
OAAI
Weichenhan, Dieter; Riedel, Anna; Sollier, Etienne; Toprak, Umut H.; Hey, Joschka; Breuer, Kersten; Wierzbinska, Justyna A.; Touzart, Aurore; Lutsik, Pavlo; Baehr, Marion; Ostlund, Anders; Nilsson, Tina; Jacobsson, Susanna; Edler, Marcel; Waraky, Ahmed; Behrens, Yvonne Lisa; Goehring, Gudrun; Schlegelberger, Brigitte; Steinek, Clemens; Harz, Hartmann; Leonhardt, Heinrich; Dolnik, Anna; Reinhardt, Dirk; Bullinger, Lars; Palmqvist, Lars; Lipka, Daniel B.; Plass, Christoph
ARID1A regulates DNA repair through chromatin organization and its deficiency triggers DNA damage-mediated anti-tumor immune response
NUCLEIC ACIDS RESEARCH
IF13.1
2024-04-085
OAAI
Bakr, Ali; Della Corte, Giuditta; Veselinov, Olivera; Kelekci, Simge; Chen, Mei-Ju May; Lin, Yu-Yu; Sigismondo, Gianluca; Iacovone, Marika; Cross, Alice; Syed, Rabail; Jeong, Yunhee; Sollier, Etienne; Liu, Chun-Shan; Lutsik, Pavlo; Krijgsveld, Jeroen; Weichenhan, Dieter; Plass, Christoph; Popanda, Odilia; Schmezer, Peter
Clinical impact of the genomic landscape and leukemogenic trajectories in non-intensively treated elderly acute myeloid leukemia patients (vol 37, pg 2187, 2023)
LEUKEMIA
IF13.4
2023-10-030
OAAI
Jahn, Ekaterina; Saadati, Maral; Fenaux, Pierre; Gobbi, Marco; Roboz, Gail J.; Bullinger, Lars; Lutsik, Pavlo; Riedel, Anna; Plass, Christoph; Jahn, Nikolaus; Walter, Claudia; Holzmann, Karlheinz; Hao, Yong; Naim, Sue; Schreck, Nicholas; Krzykalla, Julia; Benner, Axel; Keer, Harold N.; Azab, Mohammad; Dohner, Konstanze; Dohner, Hartmut
Clinical impact of the genomic landscape and leukemogenic trajectories in non-intensively treated elderly acute myeloid leukemia patients

非强化治疗的老年急性髓系白血病患者基因组景观和白血病发生轨迹的临床影响

LEUKEMIA
IF13.4
2023-08-1712
OAAI
Jahn, Ekaterina; Saadati, Maral; Fenaux, Pierre; Gobbi, Marco; Roboz, Gail J.; Bullinger, Lars; Lutsik, Pavlo; Riedel, Anna; Plass, Christoph; Jahn, Nikolaus; Walter, Claudia; Holzmann, Karlheinz; Hao, Yong; Naim, Sue; Schreck, Nicholas; Krzykalla, Julia; Benner, Axel; Keer, Harold N.; Azab, Mohammad; Doehner, Konstanze; Doehner, Hartmut
The GAPDH redox switch safeguards reductive capacity and enables survival of stressed tumour cells

GAPDH氧化还原开关保护还原能力并使应激肿瘤细胞存活

NATURE METABOLISM
IF20.8
2023-04-0638
OA
Talwar, Deepti; Miller, Colin G. G.; Grossmann, Justus; Szyrwiel, Lukasz; Schwecke, Torsten; Demichev, Vadim; Mikecin Drazic, Ana-Matea; Mayakonda, Anand; Lutsik, Pavlo; Veith, Carmen; Milsom, Michael D. D.; Mueller-Decker, Karin; Muelleder, Michael; Ralser, Markus; Dick, Tobias P. P.
Genetic and methylation profiles distinguish benign, malignant and spitzoid melanocytic tumors

遗传和甲基化特征区分良性，恶性和类黑素细胞肿瘤

INTERNATIONAL JOURNAL OF CANCER
IF4.7
2022-07-115
OA
Zaremba, Anne; Jansen, Philipp; Murali, Rajmohan; Mayakonda, Anand; Riedel, Anna; Philip, Manuel; Rose, Christian; Schaller, Joerg; Mueller, Hansgeorg; Kutzner, Heinz; Moller, Inga; Stadtler, Nadine; Kretz, Julia; Sucker, Antje; Bankfalvi, Agnes; Livingstone, Elisabeth; Zimmer, Lisa; Horn, Susanne; Paschen, Annette; Plass, Christoph; Schadendorf, Dirk; Hadaschik, Eva; Lutsik, Pavlo; Griewank, Klaus

研究方向

暂未获取到该数据
C
Christoph Plass
H 指数:108论文数:892被引数:5.8万
D
Dieter Weichenhan
H 指数:62论文数:335被引数:2.3万
J
Jörn Walter
H 指数:78论文数:313被引数:3.4万
R
Réka Tóth
H 指数:31论文数:153被引数:2,648
J
Joschka Hey
H 指数:15论文数:64被引数:541
D
Daniel B. Lipka
H 指数:39论文数:228被引数:5,970
K
Kersten Breuer
H 指数:8论文数:29被引数:250
A
Anna Riedel
H 指数:4论文数:19被引数:57
C
Christoph Bock
H 指数:107论文数:503被引数:4.4万
T
Thomas Lengauer
H 指数:84论文数:706被引数:4.2万