未登录Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists (vol 15, 489, 2024)设计规则：具有体内活性的 stapled peptides 及其在 Mdm2/X 抗体中的应用（卷 15，489，2024）
Chandramohan, Arun; Josien, Hubert; Yuen, Tsz Ying; Duggal, Ruchia; Spiegelberg, Diana; Yan, Lin; Juang, Yu-Chi Angela; Ge, Lan; Aronica, Pietro G.; Kaan, Hung Yi Kristal; Lim, Yee Hwee; Peier, Andrea; Sherborne, Brad; Hochman, Jerome; Lin, Songnian; Biswas, Kaustav; Nestor, Marika; Verma, Chandra S.; Lane, David P.; Sawyer, Tomi K.; Garbaccio, Robert; Henry, Brian; Kannan, Srinivasaraghavan; Brown, Christopher J.; Johannes, Charles W.; Partridge, Anthony W. .png)
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收藏Molecular Mechanism of P53 Peptide Permeation through Lipid Membranes from Solid-State NMR Spectroscopy and Molecular Dynamics SimulationsLi, Mingyue; Li, Jianguo; Lu, Xingyu; Schroder, Ryan; Chandramohan, Arun; Wuelfing, W. Peter; Templeton, Allen C.; Xu, Wei; Gindy, Marian; Kesisoglou, Filippos; Ling, Jing; Sawyer, Tomi; Verma, Chandra S.; Partridge, Anthony W.; Su, Yongchao 分享 收藏 Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug developmentWirjanata, Grennady; Lin, Jianqing; Dziekan, Jerzy Michal; El Sahili, Abbas; Chung, Zara; Tjia, Seth; Zulkifli, Nur Elyza Binte; Boentoro, Josephine; Tham, Roy; Jia, Lai Si; Go, Ka Diam; Yu, Han; Partridge, Anthony; Olsen, David; Prabhu, Nayana; Sobota, Radoslaw M.; Nordlund, Par; Lescar, Julien; Bozdech, Zbynek 分享 收藏 mRNAid, an open-source platform for therapeutic mRNA design and optimization strategiesVostrosablin, Nikita; Lim, Shuhui; Gopal, Pooja; Brazdilova, Kveta; Parajuli, Sushmita; Wei, Xiaona; Gromek, Anna; Prihoda, David; Spale, Martin; Muzdalo, Anja; Greig, Jamie; Yeo, Constance; Wardyn, Joanna; Mejzlik, Petr; Henry, Brian; Partridge, Anthony W.; Bitton, Danny A. 分享 收藏 Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonistsChandramohan, Arun; Josien, Hubert; Yuen, Tsz Ying; Duggal, Ruchia; Spiegelberg, Diana; Yan, Lin; Juang, Yu-Chi Angela; Ge, Lan; Aronica, Pietro G.; Kaan, Hung Yi Kristal; Lim, Yee Hwee; Peier, Andrea; Sherborne, Brad; Hochman, Jerome; Lin, Songnian; Biswas, Kaustav; Nestor, Marika; Verma, Chandra S.; Lane, David P.; Sawyer, Tomi K.; Garbaccio, Robert; Henry, Brian; Kannan, Srinivasaraghavan; Brown, Christopher J.; Johannes, Charles W.; Partridge, Anthony W. 分享 收藏 A high-throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell-based assays一种高通量微流体机械加工平台，可在基于细胞的测定中实现环肽的细胞内递送Kasper, Stephen H.; Otten, Stephanie; Squadroni, Brian; Orr-Terry, Cionna; Kuang, Yi; Mussallem, Lily; Ge, Lan; Yan, Lin; Kannan, Srinivasaraghavan; Verma, Chandra S.; Brown, Christopher J.; Johannes, Charles W.; Lane, David P.; Chandramohan, Arun; Partridge, Anthony W.; Roberts, Lee R.; Josien, Hubert; Therien, Alex G.; Hett, Erik C.; Howell, Bonnie J.; Peier, Andrea; Ai, Xi; Cassaday, Jason 分享 收藏 Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell deathChang, Shih Chieh; Gopal, Pooja; Lim, Shuhui; Wei, Xiaona; Chandramohan, Arun; Mangadu, Ruban; Smith, Jeffrey; Ng, Simon; Gindy, Marian; Phan, Uyen; Henry, Brian; Partridge, Anthony William 分享 收藏 STUB1 is an intracellular checkpoint for interferon gamma sensingNg, Simon; Lim, Shuhui; Sim, Adrian Chong Nyi; Mangadu, Ruban; Lau, Ally; Zhang, Chunsheng; Martinez, Sarah Bollinger; Chandramohan, Arun; Lim, U-Ming; Ho, Samantha Shu Wen; Chang, Shih Chieh; Gopal, Pooja; Hong, Lewis Z.; Schwaid, Adam; Fernandis, Aaron Zefrin; Loboda, Andrey; Li, Cai; Phan, Uyen; Henry, Brian; Partridge, Anthony W. 分享 收藏 Discovery and Structure-Based Design of Macrocyclic Peptides Targeting STUB1Ng, Simon; Brueckner, Alexander C.; Bahmanjah, Soheila; Deng, Qiaolin; Johnston, Jennifer M.; Ge, Lan; Duggal, Ruchia; Habulihaz, Bahanu; Barlock, Benjamin; Ha, Sookhee; Sadruddin, Ahmad; Yeo, Constance; Strickland, Corey; Peier, Andrea; Henry, Brian; Sherer, Edward C.; Partridge, Anthony W. 分享 收藏 Accelerated Identification of Cell Active KRAS Inhibitory Macrocyclic Peptides using Mixture Libraries and Automated Ligand Identification System (ALIS) TechnologyGarrigou, Michael; Sauvagnat, Berengere; Duggal, Ruchia; Boo, Nicole; Gopal, Pooja; Johnston, Jennifer M.; Partridge, Anthony; Sawyer, Tomi; Biswas, Kaustav; Boyer, Nicolas 分享 收藏 分享 收藏 分享 收藏 Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides (Mar, 10.1007/s11095-021-03005-z, 2021)Desai, Tanvi J.; Habulihaz, Bahanu; Cannon, Joseph R.; Chandramohan, Arun; Kaan, Hung Yi Kristal; Sadruddin, Ahmad; Yuen, Tsz Ying; Johannes, Charles; Thean, Dawn; Brown, Chris J.; Lane, David P.; Partridge, Anthony W.; Evers, Raymond; Sawyer, Tomi K.; Hochman, Jerome 分享 收藏 Liposome Click Membrane Permeability Assay for Identifying Permeable PeptidesDesai, Tanvi J.; Habulihaz, Bahanu; Cannon, Joseph R.; Chandramohan, Arun; Kaan, Hung Yi Kristal; Sadruddin, Ahmad; Yuen, Tsz Ying; Johannes, Charles; Thean, Dawn; Brown, Chris J.; Lane, David P.; Partridge, Anthony W.; Evers, Raymond; Sawyer, Tomi K.; Hochman, Jerome 分享 收藏 NanoClick: A High Throughput, Target-Agnostic Peptide Cell Permeability AssayPeier, Andrea; Ge, Lan; Boyer, Nicolas; Frost, John; Duggal, Ruchia; Biswas, Kaustav; Edmondson, Scott; Hermes, Jeffrey D.; Yan, Lin; Zimprich, Chad; Sadruddin, Ahmad; Kaan, Hung Yi Kristal; Chandramohan, Arun; Brown, Christopher J.; Thean, Dawn; Lee, Xue Er; Yuen, Tsz Ying; Ferrer-Gago, Fernando J.; Johannes, Charles W.; Lane, David P.; Sherborne, Brad; Corona, Cesear; Robers, Matthew B.; Sawyer, Tomi K.; Partridge, Anthony W. 分享 收藏 Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signalingLim, Shuhui; Boyer, Nicolas; Boo, Nicole; Huang, Chunhui; Venkatachalam, Gireedhar; Juang, Yu-Chi Angela; Garrigou, Michael; Kaan, Kristal; Duggal, Ruchia; Peh, Khong Ming; Sadruddin, Ahmad; Gopal, Pooja; Yuen, Tsz Ying; Ng, Simon; Kannan, Srinivasaraghavan; Brown, Christopher J.; Verma, Chandra; Orth, Peter; Peier, Andrea; Ge, Lan; Yu, Xiang; Bhatt, Bhavana; Chen, Feifei; Wang, Erjia; Li, Nianyu Jason; Gonzales, Raymond J.; Stoeck, Alexander; Henry, Brian; Sawyer, Tomi K.; Lane, David; Johannes, Charles W.; Biswas, Kaustav; Partridge, Anthony W. 分享 收藏 Exquisitely Specific anti-KRAS Biodegraders Inform on the Cellular Prevalence of Nucleotide-Loaded StatesLim, Shuhui; Khoo, Regina; Juang, Yu-Chi; Gopal, Pooja; Zhang, Huibin; Yeo, Constance; Peh, Khong Ming; Teo, Jinkai; Ng, Simon; Henry, Brian; Partridge, Anthony W. 分享 收藏 De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive HitsNg, Simon; Juang, Yu-Chi; Chandramohan, Arun; Kaan, Hung Yi Kristal; Sadruddin, Ahmad; Yuen, Tsz Ying; Ferrer-Gago, Fernando J.; Lee, Xue'Er Cheryl; Liew, Xi; Johannes, Charles W.; Brown, Christopher J.; Kannan, Srinivasaraghavan; Aronica, Pietro G.; Berglund, Nils A.; Verma, Chandra S.; Liu, Lijuan; Stoeck, Alexander; Sawyer, Tomi K.; Partridge, Anthony W.; Lane, David P. 分享 收藏 bioPROTACs as versatile modulators of intracellular therapeutic targets including proliferating cell nuclear antigen (PCNA)Lim, Shuhui; Khoo, Regina; Peh, Khong Ming; Teo, Jinkai; Chang, Shih Chieh; Ng, Simon; Beilhartz, Greg L.; Melnyk, Roman A.; Johannes, Charles W.; Brown, Christopher J.; Lane, David P.; Henry, Brian; Partridge, Anthony W. 分享 收藏 Macrocyclization of an all-d linear α-helical peptide imparts cellular permeabilityKannan, Srinivasaraghavan; Aronica, Pietro G. A.; Ng, Simon; Lian, Dawn Thean Gek; Frosi, Yuri; Chee, Sharon; Jiang, Shimin; Yuen, Tsz Ying; Sadruddin, Ahmad; Kaan, Hung Yi Kristal; Chandramohan, Arun; Wong, Jin Huei; Tan, Yaw Sing; Chang, Zi Wei; Ferrer-Gago, Fernando J.; Arumugam, Prakash; Han, Yi; Chen, Shiying; Renia, Laurent; Brown, Christopher J.; Johannes, Charles W.; Henry, Brian; Lane, David P.; Sawyer, Tomi K.; Verma, Chandra S.; Partridge, Anthony W. 分享 收藏 
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