Toshimichi Shinohara - Publications, H-index & Citations

Toshimichi Shinohara

University of Colorado System

51H指数

258论文数

6.9K被引数

收录论文 33

发表时间

PROGRESS IN RETINAL AND EYE RESEARCH

IF14.7

2017-09-01

116

OAAI

Periyasamy, Palsamy; Shinohara, Toshimichi

Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2014-07-01

OAAI

Palsamy, Periyasamy; Bidasee, Keshore R.; Ayaki, Masahiko; Augusteyn, Robert C.; Chan, Jefferson Y.; Shinohara, Toshimichi

Valproic acid suppresses Nrf2/Keap1 dependent antioxidant protection through induction of endoplasmic reticulum stress and Keap1 promoter DNA demethylation in human lens epithelial cells

EXPERIMENTAL EYE RESEARCH

IF2.7

2014-04-01

OAAI

Palsamy, Periyasamy; Bidasee, Keshore R.; Shinohara, Toshimichi

Spatial and temporal dynamics of two alternatively spliced regulatory factors, lens epithelium-derived growth factor (ledgf/p75) and p52, in the nucleus

CELL AND TISSUE RESEARCH

IF2.9

2014-01-30

PREAI

Nishizawa, Y; Usukura, J; Singh, DP; Chylack, LT; Shinohara, T

Biosynthesis, Characterization, and Efficacy in Retinal Degenerative Diseases of Lens Epithelium-derived Growth Factor Fragment (LEDGF1-326), a Novel Therapeutic Protein

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-06-01

OAAI

Baid, Rinku; Upadhyay, Arun K.; Shinohara, Toshimichi; Kompella, Uday B.

Low glucose under hypoxic conditions induces unfolded protein response and produces reactive oxygen species in lens epithelial cells

CELL DEATH & DISEASE

IF9.6

2012-04-19

OAAI

Elanchezhian, R.; Palsamy, P.; Madson, C. J.; Mulhern, M. L.; Lynch, D. W.; Troia, A. M.; Usukura, J.; Shinohara, T.

Deficiency of Prdx6 in lens epithelial cells induces ER stress response-mediated impaired homeostasis and apoptosis 晶状体上皮细胞中Prdx6的缺乏导致ER应激反应介导的稳态和凋亡受损

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2011-10-01

OAAI

Fatma, Nigar; Singh, Prerna; Chhunchha, Bhavana; Kubo, Eri; Shinohara, T.; Bhargavan, Biju; Singh, Dhirendra P.

Cholesterol-derived bile acids enhance the chaperone activity of α-crystallins

CELL STRESS & CHAPERONES

IF3.2

2011-09-01

OAAI

Song, Shuhua; Liang, Jack J. N.; Mulhern, Michael L.; Madson, Christian J.; Shinohara, Toshimichi

Detection of cytotoxic anti-LEDGF autoantibodies in atopic dermatitis

AUTOIMMUNITY

IF3.1

2009-07-07

PREAI

Ayaki, M; Ohoguro, N; Azuma, N; Majima, Y; Yata, K; Ibaraki, N; Singh, DP; Ko, V; Shinohara, T

Antibodies to a microbial peptide sharing sequence homology with βA3-crystallin damage lens epithelial cells in vitro and in vivo

AUTOIMMUNITY

IF3.1

2009-07-07

PREAI

Singh, DP; Sueno, T; Kikuchi, T; Guru, SC; Yu, S; Horwitz, J; Chylack, LT; Shinohara, T

LEDGF/DFS70, a major autoantigen of atopic dermatitis, is a component of keratohyalin granules

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2007-01-01

OAAI

Sugiura, Kazumitsu; Muro, Yoshinao; Nishizawa, Yuji; Okamoto, Miyako; Shinohara, Toshimichi; Tomita, Yasushi; Usukura, Jiro

Role of the unfolded protein response (UPR) in cataract formation

EXPERIMENTAL EYE RESEARCH

IF2.7

2006-09-01

PREAI

Ikesugi, Kengo; Yamamoto, Ryoko; Mulhern, Michael L.; Shinohara, Toshimichi

The unfolded protein response in lens epithelial cells from galactosemic rat lenses

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2006-09-01

128

PREAI

Mulhern, Michael L.; Madson, Christian J.; Danford, Andrew; Ikesugi, Kengo; Kador, Peter F.; Shinohara, Toshimichi

Transfer of LEDGF to the Mouse Retina Via Systemic AAV Vector Administration

MOLECULAR THERAPY

IF12

2006-01-01

OAAI

Glushakova, Lyudmyla G.; Gorbatuyk, Marina; Lu, Yuanging; Song, Sihong; Zheng, Min; Shinohara, Toshimichi; Hauswirth, William W.

LEDGF regulation of alcohol and aldehyde dehydrogenases in lens epithelial cells: stimulation of retinoic acid production and protection from ethanol toxicity

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2004-08-01

PREAI

Fatma, N; Kubo, E; Chylack, LT; Shinohara, T; Akagi, Y; Singh, DP

LEDGF activation of PKC γ and gap junction disassembly in lens epithelial cells

EXPERIMENTAL EYE RESEARCH

IF2.7

2003-05-01

PREAI

Nguyen, TA; Boyle, DL; Wagner, LM; Shinohara, T; Takemoto, DJ

Lens epithelium-derived growth factor relieves transforming growth factor-β1-induced transcription repression of heat shock proteins in human lens epithelial cells

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2003-05-01

OAAI

Sharma, P; Fatma, N; Kubo, E; Shinohara, T; Chylack, LT; Singh, DP

Transcriptional regulation of the antioxidant protein 2 gene, a thiol-specific antioxidant, by lens epithelium-derived growth factor to protect cells from oxidative stress

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2001-12-01

140

OAAI

Fatma, N; Singh, DP; Shinohara, T; Chylack, LT

Humoral immune response directed against LEDGF in patients with VKH

IMMUNOLOGY LETTERS

IF2.8

2001-10-01

PREAI

Yamada, K; Senju, S; Shinohara, T; Nakatsura, T; Murata, Y; Ishihara, M; Nakamura, S; Ohno, S; Negi, A; Nishimura, Y

Preferential induction of RET/PTC1 rearrangement by X-ray irradiation X射线照射优先诱导RET/PTC1重排

ONCOGENE

IF7.3

2000-01-21

PREAI

Mizuno, T; Iwamoto, KS; Kyoizumi, S; Nagamura, H; Shinohara, T; Koyama, K; Seyama, T; Hamatani, K

研究方向