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Songbo Xie

laboratory of molecular ophthalmology

29H指数
83论文数
2.1K被引数
收录论文 45
发表时间
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Tetrahedral DNA nano-PROTACs enable enhanced ocular penetration and efficient nucleolin degradation for choroidal neovascularization therapy四面体DNA纳米PROTACs增强了眼渗透性和有效的核仁素降解，可用于脉络膜新生血管治疗
errSignal Transduction and Targeted Therapy
IF52.7
err2026-06-30
err0
errOAAI
errJiayi Song; Xu Wei; Kai He; Ruixin Ge; Mengxuan Li; Tinghui Bai; Han Han; Caiyun You; Mengyu Liao; Wei Pan; Miao Chen; Rubens Belfort Jr.; Rodrigo Antonio Brant Fernandes; Songbo Xie; Hua Yan
err分享
err收藏
DNA Nanoflower LYTACs Enable Efficient VEGF Degradation and Verteporfin Loading for Combined Therapy of Wet Age-Related Macular DegenerationDNA纳米花LYTACs可有效降解VEGF并加载Verteporfin，用于湿性年龄相关性黄斑变性的联合治疗
errAdvanced Science
IF14.1
err2026-01-28
err0
errOAAI
errMengxuan Li; Yan Yue; Sijin Wu; Xinyu He; Jiayi Song; Shuwen Ma; Haokun Zhang; Chenyu Xu; Song Chen; Yanming Huang; Songbo Xie; Hua Yan
err分享
err收藏
Author Correction: Identification of a non-inhibitory aptameric ligand to CRL2ZYG11B E3 ligase for targeted protein degradation作者更正：鉴定一种非抑制性适配体配体，靶向CRL2ZYG11B E3连接酶以实现蛋白质降解
errNature Communications
IF15.7
err2025-12-19
err0
errOAAI
errZhihao Yang; Miao Chen; Ruixin Ge; Ping Zhou; Wei Pan; Jiayi Song; Shuwen Ma; Song Chen; Chenyu Xu; Mengyu Zhou; Wenyi Mi; Hua Ni; He Chen; Xue Yao; Xifeng Dong; Yan Chen; Jun Zhou; Chenghao Xuan; Cheng Dong; Hua Yan; Songbo Xie
err分享
err收藏
Targeting both wild-type EGFR and its drug-resistant mutants with erlotinib-aptamer conjugates使用erlotinib-aptamer偶联物靶向野生型EGFR及其耐药突变体
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-06-14
err0
PREAI
errYan Li; Jian Song; Ruixin Ge; Xiangrui Luo; Ping Zhou; Hanyue Lei; Rouhan Qian; Fan Zhang; Wei Pan; Miao Chen; Jingrui Li; Xifeng Dong; Tianliang Li; Sijin Wu; Jun Zhou; Songbo Xie
err分享
err收藏
Utilizing aptamers in targeted protein degradation strategies for disease therapy利用适配体在靶向蛋白质降解策略中的疾病治疗应用
errJOURNAL OF PATHOLOGY
IF5.2
err2025-04-10
err0
PREAI
errLi, Lin; Xie, Songbo; Zhou, Jun
err分享
err收藏
Targeting neurodegenerative disease-associated protein aggregation with proximity-inducing modalities靶向神经退行性疾病相关蛋白聚集的邻近诱导方法
errACTA PHARMACOLOGICA SINICA
IF8.4
err2025-04-07
err0
PREAI
errGe, RX; Chen, M; Li, QC; Liu, M; Zhou, J; Xie, SB
err分享
err收藏
Promising Proteolysis-Targeting Chimera for Mutant p53-R175H
errACS OMEGA
IF4.3
err2024-11-01
err0
errOAAI
errZhuang, Xinzhe; Guo, Yidan; Sun, Xiaozi; Chen, Jie; Xie, Songbo; Yang, Fengtang; Li, Jingrui
err分享
err收藏
CYLD/HDAC6 signaling regulates the interplay between epithelial-mesenchymal transition and ciliary homeostasis during pulmonary fibrosisCYLD/HDAC6信号调节肺纤维化中上皮-间质转化与纤毛稳态的相互作用
errCELL DEATH & DISEASE
IF9.6
err2024-08-09
err0
errOAAI
errNi, Hua; Chen, Miao; Dong, Dan; Zhou, Yunqiang; Cao, Yu; Ge, Ruixin; Luo, Xiangrui; Wang, Yutao; Dong, Xifeng; Zhou, Jun; Li, Dengwen; Xie, Songbo; Liu, Min
err分享
err收藏
Targeted degradation of membrane and extracellular proteins with LYTACsLYTACs对膜和胞外蛋白的靶向降解
errACTA PHARMACOLOGICA SINICA
IF8.4
err2024-08-05
err1
PREAI
errLi, Yu-yang; Yang, Yang; Zhang, Ren-shuai; Ge, Rui-xin; Xie, Song-bo
err分享
err收藏
An engineered DNA aptamer-based PROTAC for precise therapy of p53-R175H hotspot mutant-driven cancer基于工程DNA适体的PROTAC用于p53-R175H热点突变驱动的癌症的精确治疗
errSCIENCE BULLETIN
IF21.1
err2024-07-01
err6
errOAAI
errKong, Lingping; Meng, Fanlu; Zhou, Ping; Ge, Ruixin; Geng, Xiaoshan; Yang, Zhihao; Li, Guo; Zhang, Linlin; Wang, Jing; Ma, Jinfeng; Dong, Cheng; Zhou, Jun; Wu, Sijin; Zhong, Diansheng; Xie, Songbo
err分享
err收藏
KIF11 UFMylation Maintains Photoreceptor Cilium Integrity and Retinal Homeostasis
errADVANCED SCIENCE
IF14.1
err2024-04-26
err4
errOAAI
errRan, Jie; Guo, Guizhi; Zhang, Sai; Zhang, Yufei; Zhang, Liang; Li, Dengwen; Wu, Shian; Cong, Yusheng; Wang, Xiaohong; Xie, Songbo; Zhao, Huijie; Liu, Hongbin; Ou, Guangshuo; Zhu, Xueliang; Zhou, Jun; Liu, Min
err分享
err收藏
A Modified Tridecapeptide Probe for Imaging Cell Junction
errMOLECULES
IF4.6
err2024-02-25
err0
errOAAI
errLi, Jingrui; Wu, Yuhan; Liu, Chunyu; Zhang, Shu; Su, Xin; Xie, Songbo; Yang, Fengtang
err分享
err收藏
Targeted degradation of VEGF with bispecific aptamer-based LYTACs ameliorates pathological retinal angiogenesis基于双特异性适体的LYTACs靶向降解VEGF可改善病理性视网膜血管生成
errTHERANOSTICS
IF13.3
err2024-01-01
err0
errOAAI
errZhou, Ping; Zhang, Sai; Li, Lin; Zhang, Renshuai; Guo, Guizhi; Zhang, Yufei; Wang, Runa; Liu, Miaoyuan; Wang, Zhiyi; Zhao, Huijie; Yang, Guiwen; Xie, Songbo; Ran, Jie
err分享
err收藏
Peptide-based PROTACs: Current Challenges and Future Perspectives基于肽的protac: 当前的挑战和未来的前景
errCURRENT MEDICINAL CHEMISTRY
IF3.5
err2024-01-01
err13
PREAI
errWang, Huidan; Chen, Miao; Zhang, Xiaoyuan; Xie, Songbo; Qin, Jie; Li, Jingrui
err分享
err收藏
Targeted protein degradation in drug development: Recent advances and future challenges
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-12-01
err14
PREAI
errSong, Jian; Hu, Mingzheng; Zhou, Jun; Xie, Songbo; Li, Tianliang; Li, Yan
err分享
err收藏
Leveraging aptamers for targeted protein degradation利用适体进行靶向蛋白质降解
errTRENDS IN PHARMACOLOGICAL SCIENCES
IF19.9
err2023-11-01
err15
PREAI
errYang, Zhihao; Pang, Qiuxiang; Zhou, Jun; Xuan, Chenghao; Xie, Songbo
err分享
err收藏
HDAC6 deacetylates IDH1 to promote the homeostasis of hematopoietic stem and progenitor cells
errEMBO REPORTS
IF6.2
err2023-08-29
err5
errOAAI
errYang, Jia; Liu, Yang; Yin, Hanxiao; Xie, Songbo; Zhang, Linlin; Dong, Xifeng; Ni, Hua; Bu, Weiwen; Ma, Hongbo; Liu, Peng; Zhu, Haiyan; Guo, Rongxia; Sun, Lei; Wu, Yue; Qin, Juan; Sun, Baofa; Li, Dengwen; Luo, Hongbo R.; Liu, Min; Xuan, Chenghao; Zhou, Jun
err分享
err收藏
Selective degradation of the p53-R175H oncogenic hotspot mutant by an RNA aptamer-based PROTAC
errCLINICAL AND TRANSLATIONAL MEDICINE
IF6.8
err2023-01-29
err13
errOAAI
errKong, Lingping; Meng, Fanlu; Wu, Sijin; Zhou, Ping; Ge, Ruixin; Liu, Min; Zhang, Linlin; Zhou, Jun; Zhong, Diansheng; Xie, Songbo
err分享
err收藏
Inducible Degradation of Oncogenic Nucleolin Using an Aptamer-Based PROTAC使用基于适体的PROTAC诱导致癌核仁素的降解
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-01-06
err30
PREAI
errChen, Miao; Zhou, Ping; Kong, Yun; Li, Jingrui; Li, Yan; Zhang, Yao; Ran, Jie; Zhou, Jun; Chen, Yan; Xie, Songbo
err分享
err收藏
CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart
errCELL REPORTS
IF6.9
err2022-12-01
err13
errOAAI
errXie, Wei; Gao, Siqi; Yang, Yunfan; Li, Hongjie; Zhou, Junyan; Chen, Mingzhen; Yang, Song; Zhang, Yijun; Zhang, Liang; Meng, Xiaoqian; Xie, Songbo; Liu, Min; Li, Dengwen; Chen, Yan; Zhou, Jun
err分享
err收藏

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