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Synergistic antitumor effect of FRa TOP1i antibody drug conjugate, AZD5335, in combination with the PARP1 inhibitor, saruparib (AZD5305), in preclinical models of ovarian cancer Gymnopoulos, Marco; Tammali, Ravinder; De Almeida, Ana; Wang, Jixin; Myers, Claire; Albertella, Mark; Fraenkel, Paula G.; Sapra, Puja 分享 收藏
First disclosure of AZD5335, a TOP1i-ADC targeting low and high FRα-expressing ovarian cancer with superior preclinical activity vs FRα-MTI ADC Gymnopoulos, Marco; Thomas, Tima; Gasper, Diana; Anderton, Judith; Tammali, Ravinder; Rosfjord, Ed; Durham, Nick; Ward, Chris; Myers, Claire; Wang, Jixin; Zhong, Wenyan; Christ, Simon; Meinecke, Lina; Nekolla, Katharina 分享 收藏
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Preclinical evaluation of a novel B7-H4 targeted antibody-drug conjugate AZD8205 as a single agent and in combination with novel PARP inhibitor and checkpoint blockade Cazes, Alex; Kinneer, Krista; Omar, Bilal; Chesebrough, Jon; Anderton, Judith; Wang, Jixin; Staniszewska, Anna D.; Arbitman, Steven; Daita, Kalyani; Desai, Himanshi; Johnson, Yoshimi; Rothstein, Raymond; Gymnopoulos, Marco; Fabbri, Giulia; Cooper, Zachary A.; Albertella, Mark; Hammond, Scott A.; Cosulich, Sabina; Luheshi, Nadia; Sapra, Puja 分享 收藏
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Association of respiratory failure with inhibition of NaV1.6 in the phrenic nerve Klein, Rebecca M.; Layton, Mark E.; Regan, Hillary; Regan, Christopher P.; Li, Yuxing; Filzen, Tracey; Cato, Matt; Clements, Michelle K.; Wang, Jixin; Sanoja, Raul; Greshock, Thomas J.; Roecker, Anthony J.; Pero, Joseph E.; Kim, Ron; Burgey, Christopher; John, Christopher T.; Wang, Ying-Hong; Bhandari, Neetesh; Struyk, Arie; Kraus, Richard L.; Henze, Darrell A.; Houghton, Andrea K. 分享 收藏
Gut-derived lipopolysaccharide promotes alcoholic hepatosteatosis and subsequent hepatocellular carcinoma by stimulating neutrophil extracellular traps through toll-like receptor 4 肠源性脂多糖通过toll样受体4刺激中性粒细胞胞外诱捕网促进酒精性脂肪肝和随后的肝细胞癌 Liu, Yang; Zhang, Xin; Chen, Shuo; Wang, Jiazhong; Yu, Shuo; Li, Yiming; Xu, Meng; Aboubacar, Harouna; Li, Junhui; Shan, Tao; Wang, Jixin; Cao, Gang 分享 收藏
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Anti-PD-L1 and anti-CD73 combination therapy promotes T cell response to EGFR-mutated NSCLC Tu, Eric; McGlinchey, Kelly; Wang, Jixin; Martin, Philip; Ching, Steven L. K.; Floc'h, Nicolas; Kurasawa, James; Starrett, Jacqueline H.; Lazdun, Yelena; Wetzel, Leslie; Nuttall, Barrett; Ng, Felicia S. L.; Coffman, Karen T.; Smith, Paul D.; Politi, Katerina; Cooper, Zachary A.; Streicher, Katie 分享 收藏
Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Nav1.7 for the Treatment of Pain Adams, Gregory L.; Pall, Parul S.; Grauer, Steven M.; Zhou, Xiaoping; Ballard, Jeanine E.; Vavrek, Marissa; Kraus, Richard L.; Morissette, Pierre; Li, Nianyu; Colarusso, Stefania; Bianchi, Elisabetta; Palani, Anandan; Klein, Rebecca; John, Christopher T.; Wang, Deping; Tudor, Matthew; Nolting, Andrew F.; Biba, Mirlinda; Nowak, Timothy; Makarov, Alexey A.; Reibarkh, Mikhail; Buevich, Alexei, V; Zhong, Wendy; Regalado, Erik L.; Wang, Xiao; Gao, Qi; Shahripour, Aurash; Zhu, Yuping; de Simone, Daniele; Frattarelli, Tommaso; Pasquini, Nicolo' Maria; Magotti, Paola; Iaccarino, Roberto; Li, Yuxing; Solly, Kelli; Lee, Keun-Joong; Wang, Weixun; Chen, Feifei; Zeng, Haoyu; Wang, Jixin; Regan, Hilary; Amin, Rupesh P.; Regan, Christopher P.; Burgey, Christopher S.; Henze, Darrell A.; Sun, Chengzao; Tellers, David M. 分享 收藏
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