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M

Michael C. Sanguinetti

University of Utah School of Medicine

H指数:74

被引数:2.8万

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hERG1 channels and potential therapeutics for long QT syndrome

hERG1通道和长QT综合征的潜在治疗药物

JOURNAL OF PHYSIOLOGY-LONDON

IF4.4

2026-08-170

OAAI

A new twist to increase ion flow

NATURE CHEMICAL BIOLOGY

IF13.7

2024-01-240

PRE

Binding of RPR260243 at the intracellular side of the hERG1 channel pore domain slows closure of the helix bundle crossing gate

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2023-02-232

OAAI

Heritable arrhythmias associated with abnormal function of cardiac potassium channels

CARDIOVASCULAR RESEARCH

IF13.3

2020-05-1927

OAAI

Toward a Structural View of hERG Activation by the Small-Molecule Activator ICA-105574

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2019-12-2613

PREAI

Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as Models for Cardiac Channelopathies: A Primer for Non-Electrophysiologists

CIRCULATION RESEARCH

IF16.2

2018-07-0676

OAAI

Molecular Basis of Altered hERG1 Channel Gating Induced by Ginsenoside Rg3

MOLECULAR PHARMACOLOGY

IF3

2017-10-015

OAAI

Ginsenoside Rg3, a Gating Modifier of EAG Family K+ Channels

MOLECULAR PHARMACOLOGY

IF3

2016-10-017

OAAI

RETRACTION: Concerted all-or-none subunit interactions mediate slow deactivation of human ether-a-go-go-related gene K+ channels. (vol 289, pg 23428, 2014) (Retraction of Vol 289, Pg 23428, 2014)

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-10-010

OAAI

Ginsenoside Rg3 Activates Human EAG Family of K+ Channels via Allosteric Modification of Gating

BIOPHYSICAL JOURNAL

IF3.1

2016-02-011

OAAI

C-Linker Accounts for Differential Sensitivity of ERG1 and ERG2 K+ Channels to RPR260243-Induced Slow Deactivation

MOLECULAR PHARMACOLOGY

IF3

2015-07-014

OAAI

The Link between Inactivation and High-Affinity Block of hERG1 Channels

MOLECULAR PHARMACOLOGY

IF3

2015-06-0123

OAAI

Identification of the Intracellular Na+ Sensor in Slo2.1 Potassium Channels

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-06-0119

OAAI

Concatenated hERG1 Tetramers Reveal Stoichiometry of Altered Channel Gating by RPR-260243

MOLECULAR PHARMACOLOGY

IF3

2015-03-0111

OAAI

Stoichiometry of a hERG1 Agonist on Channel Gating

BIOPHYSICAL JOURNAL

IF3.1

2015-01-010

OAAI

Mechanisms of Activation of Slo2.1 Channels by Intracellular Na+

BIOPHYSICAL JOURNAL

IF3.1

2015-01-010

OAAI

RETRACTED: Concerted All-or-none Subunit Interactions Mediate Slow Deactivation of Human ether-a-go-go-related Gene K+ Channels (Retracted article. See vol. 291, pg. 21423, 2016)

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2014-08-0111

OAAI

HERG1 channel agonists and cardiac arrhythmia

CURRENT OPINION IN PHARMACOLOGY

IF4.2

2014-04-0159

OAAI

Stoichiometry of altered hERG1 channel gating by small molecule activators

JOURNAL OF GENERAL PHYSIOLOGY

IF2.9

2014-03-1723

OAAI

N-Terminal Regulation of hERG1 K+ Channel Deactivation

BIOPHYSICAL JOURNAL

IF3.1

2014-01-010

OAAI