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S

Shuo Tian

chinese people's liberation army general hospital
H指数:26
被引数:2,490

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Human iPSCs Derived MSCs-Secreted Exosomes Modulate Senescent Nucleus Pulposus Cells Induced Macrophage Polarization via Metabolic Reprogramming to Mitigate Intervertebral Disc Degeneration

人源诱导多能干细胞来源的间充质干细胞分泌的外泌体通过代谢重编程调节诱导的巨噬细胞极化，以缓解椎间盘退变

Advanced Science
IF14.1
2025-07-060
OA
Qian Xiang; Jiawen Zhan; Shuo Tian; Yongzhao Zhao; Zhenquan Wu; Jialiang Lin; Longting Chen; Longjie Wang; Shuai Jiang; Zhuoran Sun; Weishi Li
Exosomes derived from MSCs exposed to hypoxic and inflammatory environments slow intervertebral disc degeneration by alleviating the senescence of nucleus pulposus cells through epigenetic modifications

来源于暴露于缺氧和炎症环境中的MSCs的细胞外囊泡，通过表观遗传修饰缓解髓核细胞的衰老，从而延缓椎间盘退变。

BIOACTIVE MATERIALS
IF20.3
2025-07-010
PRE
Zhao, Yongzhao; Chen, Longting; Jiang, Shuai; Wu, Zhenquan; Xiang, Qian; Lin, Jialiang; Tian, Shuo; Sun, Zhuoran; Sun, Chuiguo; Li, Weishi
The microglial state transition as a novel mechanism by which fresh Baihe Dihuang decoction prevents depression by regulating SIRT1/ HMGB1 signaling

小胶质细胞状态转换作为一种新颖机制，通过调节SIRT1/HMGB1信号通路，使新鲜百合地黄汤能够预防抑郁症。

PHYTOMEDICINE
IF8.3
2025-06-010
PRE
Cao, Li-Hua; Wang, Zhen-Zhen; Zhao, Hui; Tian, Shuo; He, Hong-Juan; Miao, Jin-Xin; Huang, Sheng-nan; Wang, Xiao-Yu; Song, Ya-Gang; Kang, Le; Wang, Hao-Yang; Wang, Can; Bai, Ming; Gao, Song

研究方向

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杜
杜冠华
H 指数:80论文数:1,144被引数:2.9万
I
Ienglam Lei
H 指数:17论文数:59被引数:1,047
M
Mingsan Miao
H 指数:21论文数:139被引数:1,253
Y
Yagang Song
H 指数:9论文数:61被引数:406
王
王忠
H 指数:36论文数:86被引数:5,045
X
X. Peter
H 指数:110论文数:315被引数:4.6万
X
Xiangxiang Wu
H 指数:15论文数:107被引数:882
W
Weishi Li
H 指数:39论文数:392被引数:6,604
Y
Yongzhao Zhao
H 指数:17论文数:49被引数:933
J
Jialiang Lin
H 指数:28论文数:127被引数:2,333