logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
M

Marcel P. Trefny

university of basel
H指数:17
被引数:4,602

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Cytotoxic CD39+ tumor-associated NK cells respond to NKG2A blockade in lung cancer

肺癌中细胞毒性CD39<sup>+</sup>肿瘤相关NK细胞对NKG2A阻断的反应

Science Immunology
IF16.3
2026-06-050
PRE
Clara Serger; Lucas Rebuffet; Michael T. Sandholzer; Wiebke Rackwitz; Irene Fusi; Petra Herzig; Annalea Brüggemann; Carina A. Pawlow; Evgeny Chichelnitskiy; Daniel Hajnal; Nicole Oelgarth; Sarp Uzun; Christoph Schultheiß; Andreas Zingg; Sofia Tundo; Thuy T. Luu; Aljaz Hojski; Didier Lardinois; Lavinia Neubert; Mascha Binder; Kirsten Mertz; Marcel P. Trefny; Nicole Kirchhammer; Marina Natoli; Matthias S. Matter; Heinz Läubli; Christine Falk; Karin Schaeuble; Eric Vivier; Andrea Romagnani; Alfred Zippelius
Ablation of prostaglandin E2 signalling through dual receptor knockout in CAR T cells enhances therapeutic efficacy in solid tumours

通过CAR T细胞中的双重受体敲除消除前列腺素E2信号传导可增强实体瘤的治疗效果

Nature Biomedical Engineering
IF26.6
2026-02-110
OAAI
Janina Dörr; Lisa Gregor; Sebastian B. Lacher; Arman Oner; Yi Sun; Ignazio Piseddu; Luisa Fertig; Sebastijan Spajic; Stefanie Lesch; Stefanos Michaelides; Matthias Seifert; Adrian Gottschlich; Natasha Samson; Lina Majed; Daria Briukhovetska; Donjetë Simnica; Viktoria Hartmann; Kathrin Gabriel; Sonia Cohen; Genevieve M. Boland; David Andreu-Sanz; Emanuele Carlini; Sophia Stock; Anne Holtermann; Philipp Jie Müller; Thaddäus Strzalkowski; Marcel P. Trefny; Stefan Endres; Russell W. Jenkins; Jan P. Böttcher; Sebastian Kobold
Dissection of single-cell landscapes for the development of chimeric antigen receptor T cells in Hodgkin lymphoma

解析霍奇金淋巴瘤中嵌合抗原受体T细胞发展的单细胞景观

BLOOD
IF23.1
2025-04-031
PRE
Gottschlich, Adrian; Gruenmeier, Ruth; Hoffmann, Gordon Victor; Nandi, Sayantan; Kavaka, Vladyslav; Mueller, Philipp Jie; Jobst, Jakob; Oner, Arman; Kaiser, Rainer; Gaertig, Jan; Piseddu, Ignazio; Frenz-Wiessner, Stephanie; Fairley, Savannah D.; Schulz, Heiko; Igl, Veronika; Janert, Thomas Alexander; Di Fina, Lea; Mulkers, Maite; Thomas, Moritz; Briukhovetska, Daria; Simnica, Donjete; Carlini, Emanuele; Tsiverioti, Christina Angeliki; Trefny, Marcel P.; Lorenzini, Theo; Maerkl, Florian; Mesquita, Pedro; Brabenec, Ruben; Strzalkowski, Thaddaeus; Stock, Sophia; Michaelides, Stefanos; Hellmuth, Johannes; Thelen, Martin; Reinke, Sarah; Klapper, Wolfram; Gelebart, Pascal Francois; Nicolai, Leo; Marr, Carsten; Beltran, Eduardo; Megens, Remco T. A.; Klein, Christoph; Baran-Marszak, Fanny; Rosenwald, Andreas; von Bergwelt-Baildon, Michael; Broeckelmann, Paul J.; Endres, Stefan; Kobold, Sebastian
Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses

肿瘤来源的前列腺素E2程序cDC1功能障碍损害肿瘤内组织的抗癌T细胞反应

IMMUNITY
IF26.3
2023-06-0162
OA
Bayerl, Felix; Meiser, Philippa; Donakonda, Sainitin; Hirschberger, Anna; Lacher, Sebastian B.; Pedde, Anna-Marie; Hermann, Chris D.; Elewaut, Anais; Knolle, Moritz; Ramsauer, Lukas; Rudolph, Thomas J.; Grassmann, Simon; Oellinger, Rupert; Kirchhammer, Nicole; Trefny, Marcel; Anton, Martina; Wohlleber, Dirk; Hoechst, Bastian; Zaremba, Anne; Krueger, Achim; Rad, Roland; Obenauf, Anna C.; Schadendorf, Dirk; Zippelius, Alfred; Buchholz, Veit R.; Schraml, Barbara U.; Boettcher, Jan P.
N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer
CELL REPORTS MEDICINE
IF10.6
2023-04-014
OAAI
der Maur, Priska Auf; Trefny, Marcel P.; Baumann, Zora; Vulin, Milica; Correia, Ana Luisa; Diepenbruck, Maren; Kramer, Nicolas; Volkmann, Katrin; Preca, Bogdan-Tiberius; Ramos, Pedro; Leroy, Cedric; Eichlisberger, Tobias; Buczak, Katarzyna; Zilli, Federica; Okamoto, Ryoko; Rad, Roland; Jensen, Michael Rugaard; Fritsch, Christine; Zippelius, Alfred; Stadler, Michael B.; Bentires-Alj, Mohamed
Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy
NATURE COMMUNICATIONS
IF15.7
2023-02-0229
OAAI
Trefny, Marcel P.; Kirchhammer, Nicole; Auf der Maur, Priska; Natoli, Marina; Schmid, Dominic; Germann, Markus; Rodriguez, Laura Fernandez; Herzig, Petra; Lotscher, Jonas; Akrami, Maryam; Stinchcombe, Jane C.; Stanczak, Michal A.; Zingg, Andreas; Buchi, Melanie; Roux, Julien; Marone, Romina; Don, Leyla; Lardinois, Didier; Wiese, Mark; Jeker, Lukas T.; Bentires-Alj, Mohamed; Rossy, Jeremie; Thommen, Daniela S.; Griffiths, Gillian M.; Laubli, Heinz; Hess, Christoph; Zippelius, Alfred
Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-11-0290
OA
Stanczak, Michal A.; Mantuano, Natalia Rodrigues; Kirchhammer, Nicole; Sanin, David E.; Jacob, Francis; Coelho, Ricardo; Everest-Dass, Arun V.; Wang, Jinyu; Trefny, Marcel P.; Monaco, Gianni; Barenwaldt, Anne; Gray, Melissa A.; Petrone, Adam; Kashyap, Abhishek S.; Glatz, Katharina; Kasenda, Benjamin; Normington, Karl; Broderick, James; Peng, Li; Pearce, Oliver M. T.; Pearce, Erika L.; Bertozzi, Carolyn R.; Zippelius, Alfred; Laubli, Heinz
Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12 (vol 49, 1148.e1, 2018)

成功的Anti-PD-1癌症免疫疗法需要涉及细胞因子ifn-γ 和IL-12的T细胞-树突状细胞串扰 (vol 49，1148.e1，2018)

IMMUNITY
IF26.3
2022-09-0112
OAAI
Garris, Christopher S.; Arlauckas, Sean P.; Kohler, Rainer H.; Trefny, Marcel P.; Garren, Seth; Piot, Cecile; Engblom, Camilla; Pfirschke, Christina; Siwicki, Marie; Gungabeesoon, Jeremy; Freeman, Gordon J.; Warren, Sarah E.; Ong, SuFey; Browning, Erica; Twitty, Christopher G.; Pierce, Robert H.; Le, Mai H.; Algazi, Alain P.; Daud, Adil I.; Pai, Sara I.; Zippelius, Alfred; Weissleder, Ralph; Pittet, Mikael J.
NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunity
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-07-1334
OA
Kirchhammer, Nicole; Trefny, Marcel P.; Natoli, Marina; Bruecher, Dominik; Smith, Sheena N.; Werner, Franziska; Koch, Victoria; Schreiner, David; Bartoszek, Ewelina; Buchi, Melanie; Schmid, Markus; Breu, Daniel; Hartmann, K. Patricia; Zaytseva, Polina; Thommen, Daniela S.; Laeubli, Heinz; Boettcher, Jan P.; Stanczak, Michal A.; Kashyap, Abhishek S.; Plueckthun, Andreas; Zippelius, Alfred
Hepatic stellate cells suppress NK cell-sustained breast cancer dormancy

肝星状细胞抑制NK细胞持续的乳腺癌休眠

Nature
IF48.5
2021-06-020
PREAI
Ana Luísa Correia; Joao C. Guimaraes; Priska Auf der Maur; Duvini De Silva; Marcel P. Trefny; Ryoko Okamoto; Sandro Bruno; Alexander Schmidt; Kirsten Mertz; Katrin Volkmann; Luigi Terracciano; Alfred Zippelius; Marcus Vetter; Christian Kurzeder; Walter Paul Weber; Mohamed Bentires-Alj
CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors

CD36-mediated代谢适应支持调节性T细胞在肿瘤中的存活和功能

NATURE IMMUNOLOGY
IF27.6
2020-02-17418
OAAI
Wang, Haiping; Franco, Fabien; Tsui, Yao-Chen; Xie, Xin; Trefny, Marcel P.; Zappasodi, Roberta; Mohmood, Syed Raza; Fernandez-Garcia, Juan; Tsai, Chin-Hsien; Schulze, Isabell; Picard, Florence; Meylan, Etienne; Silverstein, Roy; Goldberg, Ira; Fendt, Sarah-Maria; Wolchok, Jedd D.; Merghoub, Taha; Jandus, Camilla; Zippelius, Alfred; Ho, Ping-Chih
GEF-H1 Signaling upon Microtubule Destabilization Is Required for Dendritic Cell Activation and Specific Anti-tumor Responses
CELL REPORTS
IF6.9
2019-09-0148
OAAI
Kashyap, Abhishek S.; Fernandez-Rodriguez, Laura; Zhao, Yun; Monaco, Gianni; Trefny, Marcel P.; Yoshida, Naohiro; Martin, Kea; Sharma, Ashwani; Olieric, Natacha; Shah, Pankaj; Stanczak, Michal; Kirchhammer, Nicole; Park, Sung-Moo; Wieckowski, Sebastien; Laubli, Heinz; Zagani, Rachid; Kasenda, Benjamin; Steinmetz, Michel O.; Reinecker, Hans-Christian; Zippelius, Alfred
Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12

成功的Anti-PD-1癌症免疫疗法需要涉及细胞因子ifn-γ 和IL-12的T细胞-树突状细胞串扰

IMMUNITY
IF26.3
2018-12-01720
OAAI
Garris, Christopher S.; Arlauckas, Sean P.; Kohler, Rainer H.; Trefny, Marcel P.; Garren, Seth; Piot, Cecile; Engblom, Camilla; Pfirschke, Christina; Siwicki, Marie; Gungabeesoon, Jeremy; Freeman, Gordon J.; Warren, Sarah E.; Ong, Sufey; Browning, Erica; Twitty, Christopher G.; Pierce, Robert H.; Le, Mai H.; Algazi, Alain P.; Daud, Adil I.; Pai, Sara I.; Zippelius, Alfred; Weissleder, Ralph; Pittet, Mikael J.
Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2018-09-24217
OA
Stanczak, Michal A.; Siddiqui, Shoib S.; Trefny, Marcel P.; Thommen, Daniela S.; Boligan, Kayluz Frias; von Gunten, Stephan; Tzankov, Alexandar; Tietze, Lothar; Lardinois, Didier; Heinzelmann-Schwarz, Viola; von Bergwelt-Baildon, Michael; Zhang, Wu; Lenz, Heinz-Josef; Han, Younghun; Amos, Christopher I.; Syedbasha, Mohammedyaseen; Egli, Adrian; Stenner, Frank; Speiser, Daniel E.; Varki, Ajit; Zippelius, Alfred; Laubli, Heinz

研究方向

暂未获取到该数据
A
Alfred Zippelius
H 指数:74论文数:553被引数:2.6万
H
Heinz Läubli
H 指数:49论文数:228被引数:8,561
N
Nicole Kirchhammer
H 指数:13论文数:34被引数:1,297
M
Michal A. Stanczak
H 指数:26论文数:65被引数:2,945
P
Priska Auf der Maur
H 指数:8论文数:14被引数:753
D
Daniela S. Thommen
H 指数:25论文数:206被引数:7,929
S
Sebastian Kobold
H 指数:50论文数:340被引数:1.0万
M
Mohamed Bentires‐Alj
H 指数:48论文数:168被引数:1.0万
K
Kirsten D. Mertz
H 指数:48论文数:281被引数:1.0万
D
Didier Lardinois
H 指数:49论文数:285被引数:1.1万