Xiongyi Huang

California Institute of Technology

H指数:27

被引数:5,051

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Sequence Display generates large-scale sequence–activity datasets for reprogramming SlugCas9 toward difficult-to-access PAMs

序列展示技术为重编程SlugCas9以靶向难以接近的PAMs生成了大规模序列-活性数据集

Nature Communications

IF15.7

2026-10-300

OAAI

Sequence Display enables large-scale sequence–activity datasets for rapid protein evolution

序列显示功能支持大规模序列-活性数据集，以实现蛋白质的快速进化。

Nature Biotechnology

IF41.7

2026-04-080

PRE

Engineering non-haem enzymes for nickel-catalysed C(sp2)‒S coupling via ligand-to-metal charge transfer photocatalysis

通过配体-金属电荷转移光催化用于镍催化的C(sp2) s偶联的工程非血红素酶

Nature Synthesis

IF20

2026-02-270

PRE

Biocatalytic Synthesis of N-Protected α-Amino Acids through 1; 3-Nitrogen Migration by Nonheme Iron Enzymes

非血红素铁酶通过1,3-氮迁移催化合成N-保护α-氨基酸

Journal of the American Chemical Society

IF15.6

2025-11-200

PRE

Enantioconvergent benzylic C(sp3)‒N coupling with a copper-substituted nonheme enzyme

手性汇聚的苄基C(sp³)‒N偶联反应与铜取代的非血红素酶

Science

IF45.8

2025-08-140

Biocatalytic Olefin Difunctionalization for Synthesis of Chiral 2-Azidoamines Using Nonheme Iron Enzymes

非血红素铁酶催化的烯烃双官能团化反应，用于合成手性2-叠氮基胺

Angewandte Chemie International Edition

IF0

2025-08-100

PRE

Directed Evolution of Copper-Substituted Nonheme Enzymes for Enantioselective Alkene Oxytrifluoromethylation

铜取代非血红素酶的定向进化用于烯烃对映选择性氧三氟甲基化

Journal of the American Chemical Society

IF15.6

2025-08-050

PRE

Unlocking Lewis acid catalysis in non-haem enzymes for an abiotic ene reaction

解锁非血红素酶中的路易斯酸催化，用于非生物烯反应

Nature Catalysis

IF44.6

2025-07-040

PRE

Merging photoredox with metalloenzymatic catalysis for enantioselective decarboxylative C(sp3)‒N3 and C(sp3)‒SCN bond formation

将光氧化还原与金属酶催化相结合，用于立体选择性脱羧C(sp³)‒N3和C(sp³)‒SCN键的形成

Nature Catalysis

IF44.6

2024-12-200

PRE

Biocatalytic Generation of Trifluoromethyl Radicals by Nonheme Iron Enzymes for Enantioselective Alkene Difunctionalization

非血红素铁酶生物催化生成三氟甲基自由基，用于对映选择性烯烃双官能化

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-12-050

PRE

Engineering non-haem iron enzymes for enantioselective C(sp3)-F bond formation via radical fluorine transfer (Mar, 10.1038/s44160-024-00507-7, 2024)

NATURE SYNTHESIS

IF20

2024-04-261

Engineering non-haem iron enzymes for enantioselective C(sp3)-F bond formation via radical fluorine transfer

工程非血红素铁酶通过自由基氟转移形成对映选择性C(sp3)-F键

NATURE SYNTHESIS

IF20

2024-03-2811

PRE

Precious metal clusters as fundamental agents in bioimaging usability

FRONTIERS IN CHEMISTRY

IF4.2

2023-11-092

OAAI

Protoglobin-Catalyzed Formation of cis-Trifluoromethyl-Substituted Cyclopropanes by Carbene Transfer

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2022-12-1935

PRE

Directed evolution of nonheme iron enzymes to access abiological radical-relay C(sp 3 )−H azidation

非血红素铁酶的定向进化以获取非生物自由基继电器C(sp <sup>3</sup> ) -- 酸化

Science

IF45.8

2022-01-010

High Throughput Screening with SAMDI Mass Spectrometry for Directed Evolution

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2020-11-1122

OAAI

Enantiodivergent α-Amino C-H Fluoroalkylation Catalyzed by Engineered Cytochrome P450s

工程细胞色素P450s催化的对映异构 α-氨基c-h氟烷基化

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2019-06-0798

OAAI

Selective C-H bond functionalization with engineered heme proteins: new tools to generate complexity

CURRENT OPINION IN CHEMICAL BIOLOGY

IF6.1

2019-04-01109

OAAI

A Biocatalytic Platform for Synthesis of Chiral α-Trifluoromethylated Organoborons

用于合成手性 α-三氟甲基化有机硼的生物催化平台

ACS CENTRAL SCIENCE

IF10.4

2019-02-0181

OAAI

Site-selective 18F fluorination of unactivated C-H bonds mediated by a manganese porphyrin

CHEMICAL SCIENCE

IF7.4

2018-01-0171

OAAI

Xiongyi Huang

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