Linda M. McAllister‐Lucas

university of pittsburgh

26H指数

145论文数

3.1K被引数

收录论文 42

发表时间

MALT1 protease inhibition restrains glioblastoma progression by reversing tumor-associated macrophage-dependent immunosuppression in mice MALT1蛋白酶抑制通过逆转肿瘤相关巨噬细胞依赖的免疫抑制抑制胶质母细胞瘤进展（在小鼠中）

Nature Communications

IF15.7

2026-08-10

OAAI

Juliana Hofstätter Azambuja; Saigopalakrishna S. Yerneni; Lisa M. Maurer; Hannah E. Crentsil; Gabriela N. Debom; Linda Klei; Mei Smyers; Chaim T. Sneiderman; Kristina E. Schwab; Rajesh Acharya; Aivi T. Nguyen; Josie L. Emery; John W. Little; Jeffrey A. Meridew; Yijen Lin Wu; Prasanna Ekambaram; Dong Hu; Pete J. Gough; John Bertin; Ari Melnick; Gary Kohanbash; Riyue Bao; Peter C. Lucas; Linda M. McAllister-Lucas

p95HER2, a truncated form of the HER2 oncoprotein, drives an immunosuppressive program in HER2+ breast cancer that limits trastuzumab deruxtecan efficacy p95HER2，HER2癌蛋白的一种截断形式，在HER2+乳腺癌中驱动一种免疫抑制程序，限制了T-DXd（trastuzumab deruxtecan）的疗效。

Nature Cancer

IF28.5

2025-06-27

PREAI

Dong Hu; Xiaoshuang Lyu; Zheqi Li; Prasanna Ekambaram; Anushka Dongre; Tanner Freeman; Marion Joy; Jennifer M. Atkinson; Daniel D. Brown; Zongyou Cai; Neil M. Carleton; Hannah E. Crentsil; John Little; Felicia Kemp; Linda R. Klei; Maria Beecher; Jeff Sperinde; Weidong Huang; Heikki Joensuu; Ashok Srinivasan; Katherine L. Pogue-Geile; Ying Wang; Huichen Feng; Lisa D. Eli; Alshad S. Lalani; Jian Zou; George C. Tseng; Tullia C. Bruno; Adrian V. Lee; Steffi Oesterreich; Norman Wolmark; Carmen J. Allegra; Samuel A. Jacobs; Linda M. McAllister-Lucas; Peter C. Lucas

CARD9 BLOCKADE OFFERS A NEW OPPORTUNITY TO REPROGRAM TUMOR-ASSOCIATED MACROPHAGES IN GLIOBLASTOMA

NEURO-ONCOLOGY

IF13.4

2024-11-11

PREAI

Hofstatter Azambuja, Juliana; Yerneni, Saigopalakrishna; Maurer, Lisa; Crentsil, Hannah; Debom, Gabriela; Klei, Linda; Smyers, Mei; Sneiderman, Chaim; Schwab, Kristina; Acharya, Rajesh; Wu, Yijen Lin; Ekambaram, Prasanna; Hu, Dong; Gough, Pete; Foley, Kevin; Bertin, John; Melnick, Ari; Kohanbash, Gary; Bao, Riyue; Lucas, Peter; McAllister-Lucas, Linda

ENGINEERING MRNA THERAPIES FOR BRAIN TUMORS

NEURO-ONCOLOGY

IF13.4

2024-11-11

PREAI

Yerneni, Saigopalakrishna; Azambuja, Juliana Hofstatter; Strelkova-Petersen, Daria; Gallagher, Brendan; Kim, Julie Shin; Chaudhary, Namit; Zhao, Yongxin; Lucas, Peter; McAllister-Lucas, Linda; Pardi, Norbert; Weissman, Drew; Whitehead, Kathryn

MALT1 IN H3K27-ALTERED DIFFUSE MIDLINE GLIOMA

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Butterfield, Hannah E.; Azambuja, Juliana Hofstatter; Maurer, Lisa; Hu, Dong; Cruz, Andrea F.; Halbert, Matthew E.; Gatesman, Taylor A.; Little, John; Agnihotri, Sameer; Lucas, Peter C.; McAllister-Lucas, Linda M.

MALT1 as a regulator of tumor progression in H3K27-altered diffuse midline glioma

CANCER RESEARCH

IF16.6

2024-03-04

PREAI

Butterfield, Hannah; Azambuja, Juliana Hofstatter; Maurer, Lisa; Yerneni, Saigopalakrishna S.; Cruz, Andrea; Halbert, Matthew; Gatesman, Taylor; Agnihotri, Sameer; Lucas, Peter C.; McAllister-Lucas, Linda M.

Dual benefit of MALT1 blockade in glioblastoma

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Azambuja, Juliana Hofstatter; Yerneni, Saigopalakrishna S.; Debom, Gabriela N.; Maurer, Lisa M.; Butterfield, Hannah E.; Klei, Linda R.; Kohanbash, Gary; Lucas, Peter C.; McAllister-Lucas, Linda M.

MALT1 is activated by doxorubicin and mediates therapy resistance in triple-negative breast cancer

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Beecher, Maria; Hu, Dong; Klei, Linda; Little, Jack; McAllister-Lucas, Linda M.; Lucas, Peter C.

Enabling mRNA medicine for brain tumors

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Yerneni, Saigopalakrishna S.; Azambuja, Juliana H.; Lucas, Peter C.; McAllister-Lucas, Linda; Whitehead, Kathryn A.

The american pediatric society and society for pediatric research joint statement against racism and social injustice (Aug, 2021, 10.1038/s41390-020-01107-9)

PEDIATRIC RESEARCH

IF3.1

2021-08-13

OAAI

Abman, Steven H.; Armstrong, Sarah; Baker, Susan; Bogue, Clifford W.; Carlo, Waldemar; Chalak, Lina; Daniels, Stephen R.; Davis, Stephanie; Debaun, Michael R.; Fike, Candice; Frazer, Lauren; Gibson, Keisha; Gill, Michelle; Glass, Hannah; Gordon, Catherine M.; Goyal, Monika; Hirschhorn, Joel; Holtz, Lori; Hunstad, David A.; Leonard, Mary B.; Maitre, Nathalie; Markham, Larry; McAllister-Lucas, Linda; Orange, Jordan; Shah, Prachi; Simon, Tamara; Steinhorn, Robin H.; Tarini, Beth; Walker-Harding, Leslie R.

Canonical and Non-Canonical Roles of GRK2 in Lymphocytes

CELLS

IF5.2

2021-02-03

OAAI

Cheng, Jing; Lucas, Peter C.; McAllister-Lucas, Linda M.

The american pediatric society and society for pediatric research joint statement against racism and social injustice

PEDIATRIC RESEARCH

IF3.1

2020-09-03

OAAI

Abman, Steven H.; Armstrong, Sarah; Baker, Susan; Bogue, Clifford W.; Carlo, Waldemar; Chalak, Lina; Daniels, Stephen R.; Davis, Stephanie; Debaun, Michael R.; Fike, Candice; Frazer, Lauren; Gibson, Keisha; Gill, Michelle; Glass, Hannah; Gordon, Catherine M.; Goyal, Monika; Hirschhorn, Joel; Holtz, Lori; Hunstad, David; Leonard, Mary B.; Maitre, Nathalie; Markham, Larry; McAllister-Lucas, Linda; Orange, Jordan; Shah, Prachi; Simon, Tamar; Steinhorn, Robin H.; Tarini, Beth; Walker-Harding, Leslie R.

Critical protein-protein interactions within the CARMA1-BCL10-MALT1 complex: Take-home points for the cell biologist

CELLULAR IMMUNOLOGY

IF2.9

2020-09-01

PREAI

Cheng, Jing; Maurer, Lisa M.; Kang, Heejae; Lucas, Peter C.; McAllister-Lucas, Linda M.

Inhibition of BCL10-MALT1 interaction to treat diffuse large B-cell lymphoma

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Kang, Heejae; Hu, Dong; Murai, Marcelo; Mady, Ahmed; Chen, Bill; Nikolovska-Coleska, Zaneta; McAllister-Lucas, Linda M.; Lucas, Peter C.

MALT1 Protease Plays a Dual Role in the Allergic Response by Acting in Both Mast Cells and Endothelial Cells

JOURNAL OF IMMUNOLOGY

IF3.4

2020-05-01

OAAI

Alfano, Danielle N.; Klei, Linda R.; Klei, Hanna B.; Trotta, Matthew; Gough, Peter J.; Foley, Kevin P.; Bertin, John; Sumpter, Tina L.; Lucas, Peter C.; McAllister-Lucas, Linda M.

GRK2 suppresses lymphomagenesis by inhibiting the MALT1 proto-oncoprotein

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2020-01-21

OAAI

Cheng, Jing; Klei, Linda R.; Hubel, Nathaniel E.; Zhang, Ming; Schairer, Rebekka; Maurer, Lisa M.; Klei, Hanna B.; Kang, Heejae; Concel, Vincent J.; Delekta, Phillip C.; Dang, Eric, V; Mintz, Michelle A.; Baens, Mathijs; Cyster, Jason G.; Parameswaran, Narayanan; Thome, Margot; Lucas, Peter C.; McAllister-Lucas, Linda M.

MALT1 is a critical mediator of PAR1-driven NF-κB activation and metastasis in multiple tumor types

ONCOGENE

IF7.3

2019-08-16

PREAI

McAuley, J. Randall; Bailey, Kelly M.; Ekambaram, Prasanna; Klei, Linda R.; Kang, Heejae; Hu, Dong; Freeman, Tanner J.; Concel, Vincent J.; Hubel, Nathaniel E.; Lee, Jia-Ying (Lloyd); Klei, Hanna B.; Cheng, Jing; Sekar, Preethiya; Bridwell, Rachel E.; Covic, Lidija; Lucas, Peter C.; McAllister-Lucas, Linda M.

Ibrutinib significantly inhibited Bruton's tyrosine kinase (BTK) phosphorylation, in-vitro proliferation and enhanced overall survival in a preclinical Burkitt lymphoma (BL) model

ONCOIMMUNOLOGY

IF6.3

2018-10-11

OAAI

Chu, Yaya; Lee, Sanghoon; Shah, Tishi; Yin, Changhong; Barth, Matthew; Miles, Rodney R.; Ayello, Janet; Morris, Erin; Harrison, Lauren; Van de Ven, Carmella; Galardy, Paul; Goldman, Stanton C.; Lim, Megan S.; Hermiston, Michelle; McAllister-Lucas, Linda M.; Giulino-Roth, Lisa; Perkins, Sherrie L.; Cairo, Mitchell S.

CARMA3 Is a Critical Mediator of G Protein-Coupled Receptor and Receptor Tyrosine Kinase-Driven Solid Tumor Pathogenesis

FRONTIERS IN IMMUNOLOGY

IF5.9

2018-08-15

OAAI

McAuley, J. Randall; Freeman, Tanner J.; Ekambaram, Prasanna; Lucas, Peter C.; McAllister-Lucas, Linda M.

The CARMA3-Bcl10-MALT1 Signalosome Drives NFκB Activation and Promotes Aggressiveness in Angiotensin II Receptor-Positive Breast Cancer

CANCER RESEARCH

IF16.6

2018-02-28

OAAI

Ekambaram, Prasanna; Lee, Jia-Ying (Lloyd); Hubel, Nathaniel E.; Hu, Dong; Yerneni, Saigopalakrishna; Campbell, Phil G.; Pollock, Netanya; Klei, Linda R.; Concel, Vincent J.; Delekta, Phillip C.; Chinnaiyan, Arul M.; Tomlins, Scott A.; Rhodes, Daniel R.; Priedigkeit, Nolan; Lee, Adrian V.; Oesterreich, Steffi; McAllister-Lucas, Linda M.; Lucas, Peter C.

研究方向