Brendan D. Manning - Publications, H-index & Citations

Brendan D. Manning

harvard t.h. chan school of public health

71H指数

223论文数

4.2W被引数

收录论文 86

发表时间

Dietary protein governs the role of insulin signaling in the postprandial regulation of hepatic mTORC1 饮食蛋白质调控胰岛素信号在餐后肝mTORC1调节中的作用

Nature Communications

IF15.7

2026-08-31

OAAI

Krystle C. Kalafut; Yann Cormerais; Madi Y. Cissé; Samuel C. Lapp; Karen E. Inouye; Gökhan S. Hotamışlıgil; Brendan D. Manning

LIFe of the sugar-free party in cancer metabolism 癌症代谢中无糖聚会的LIFe

trends in endocrinology & metabolism

IF0

2026-04-09

PREAI

Khaled Tighanimine; Brendan D. Manning

Growth factor-independent mTORC1 signaling promotes primary cilia length via suppression of autophagy 生长因子非依赖性mTORC1信号通过抑制自噬促进主纤毛长度。

iScience

IF4.1

2025-11-25

OAAI

Jong Shin; Khaled Tighanimine; Yann Cormerais; Dean M. Rosenthal; Pratima Niroula; Samuel C. Lapp; Krystle C. Kalafut; Madi Y. Cisse; Sandra Schrötter; Brendan D. Manning

Extracellular vesicle and particle-based blood test for ovarian cancer screening of average risk population: a promising nested case control study using preclinical samples 基于细胞外囊泡和颗粒的血液检测用于卵巢癌筛查（针对平均风险人群）：一项使用预临床样本的嵌套病例对照研究，具有前景。

Gynecologic Oncology

IF3.7

2025-10-23

OAAI

Brendan Manning; Sanchari Banerjee; Troy B. Hawkins; Emily S. Winn-Deen; Laura T. Bortolin; Brittany Grimes; Timothy Santos-Heiman; Delaney M. Byrne; MacKenzie S. King; Daniel P. Salem; Michael Smith; Anthony D. Couvillon; Sophia Apostolidou; Aleksandra Gentry-Maharaj; Steven J. Skates; Christine D. Berg; David F. Ransohoff; Toumy Guettouche; Dawn R. Mattoon; Usha Menon

Evolution of growth factor signaling to the TSC complex to regulate mTORC1 生长因子信号向TSC复合物的演化以调节mTORC1

Science Signaling

IF6.6

2025-07-08

PREAI

Kun Wang; Sophie E. Lockwood; Brendan D. Manning

AKT-mediated phosphorylation of TSC2 controls stimulus- and tissue-specific mTORC1 signaling and organ growth AKT介导的TSC2磷酸化调控刺激特异性和组织特异性的mTORC1信号通路及器官生长

Developmental Cell

IF8.7

2025-06-05

PREAI

Yann Cormerais; Samuel C. Lapp; Krystle C. Kalafut; Madi Y. Cissé; Jong Shin; Benjamin Stefadu; Jean Personnaz; Sandra Schrötter; Jessica Freed; Angelica D’Amore; Emma R. Martin; Catherine L. Salussolia; Mustafa Sahin; Suchithra Menon; Vanessa Byles; Brendan D. Manning

Growth Signaling Networks Orchestrate Cancer Metabolic Networks

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE

IF10.1

2024-03-04

PREAI

Manning, Brendan D.; Dibble, Christian C.

S6K1 Regulates GSK3 under Conditions of mTOR-Dependent Feedback Inhibition of Akt (vol 24, pg 185, 2006)

MOLECULAR CELL

IF16.6

2023-09-01

OAAI

Zhang, Hui H.; Lipovsky, Alex I.; Dibble, Christian C.; Sahin, Mustafa; Manning, Brendan D.

The TSC1-TSC2 complex is required for proper activation of mTOR complex 2

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

478

OAAI

Huang, Jingxiang; Dibble, Christian C.; Matsuzaki, Mika; Manning, Brendan D.

Characterization of Rictor Phosphorylation Sites Reveals Direct Regulation of mTOR Complex 2 by S6K1

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

422

OAAI

Dibble, Christian C.; Asara, John M.; Manning, Brendan D.

NF2/Merlin Is a Novel Negative Regulator of mTOR Complex 1, and Activation of mTORC1 Is Associated with Meningioma and Schwannoma Growth NF2/Merlin是mTOR复合物1的新型负调节因子，mTORC1的激活与脑膜瘤和神经鞘瘤的生长有关

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

258

OAAI

James, Marianne F.; Han, Sangyeul; Polizzano, Carolyn; Plotkin, Scott R.; Manning, Brendan D.; Stemmer-Rachamimov, Anat O.; Gusella, James F.; Ramesh, Vijaya

Sterol Regulatory Element Binding Protein Regulates the Expression and Metabolic Functions of Wild-Type and Oncogenic IDH1

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-17

OAAI

Ricoult, Stephane J. H.; Dibble, Christian C.; Asara, John M.; Manning, Brendan D.

mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid species

NATURE METABOLISM

IF20.8

2022-12-19

OAAI

Hosios, Aaron M.; Wilkinson, Meghan E.; McNamara, Molly C.; Kalafut, Krystle C.; Torrence, Margaret E.; Asara, John M.; Manning, Brendan D.

DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting DEPDC5-dependent mTORC1信号传导机制对于急性禁食的抗癫痫发作作用至关重要

CELL REPORTS

IF6.9

2022-08-01

OAAI

Yuskaitis, Christopher J.; Modasia, Jinita B.; Schrotter, Sandra; Rossitto, Leigh-Ana; Groff, Karenna J.; Morici, Christopher; Mithal, Divakar S.; Chakrabarty, Ram P.; Chandel, Navdeep S.; Manning, Brendan D.; Sahin, Mustafa

Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway

NATURE COMMUNICATIONS

IF15.7

2022-05-16

OAAI

Soflaee, Mona Hoseini; Kesavan, Rushendhiran; Sahu, Umakant; Tasdogan, Alpaslan; Villa, Elodie; Djabari, Zied; Cai, Feng; Tran, Diem H.; Vu, Hieu S.; Ali, Eunus S.; Rion, Halie; O'Hara, Brendan P.; Kelekar, Sherwin; Hallett, James Hughes; Martin, Misty; Mathews, Thomas P.; Gao, Peng; Asara, John M.; Manning, Brendan D.; Ben-Sahra, Issam; Hoxhaj, Gerta

The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth

CELL REPORTS

IF6.9

2022-05-01

OAAI

Schrotter, Sandra; Yuskaitis, Christopher J.; MacArthur, Michael R.; Mitchell, Sarah J.; Hosios, Aaron M.; Osipovich, Maria; Torrence, Margaret E.; Mitchell, James R.; Hoxhaj, Gerta; Sahin, Mustafa; Manning, Brendan D.

Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb (vol 13, pg 1259, 2003)

CURRENT BIOLOGY

IF7.5

2022-02-01

PREAI

Tee, Andrew R.; Manning, Brendan D.; Roux, Philippe P.; Cantley, Lewis C.; Blenis, John

Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin 肝mTORC1信号激活ATF4作为其对喂养和胰岛素代谢反应的一部分

MOLECULAR METABOLISM

IF6.6

2021-11-01

OAAI

Byles, Vanessa; Cormerais, Yann; Kalafut, Krystle; Barrera, Victor; Hallett, James E. Hughes; Sui, Shannan Ho; Asara, John M.; Adams, Christopher M.; Hoxhaj, Gerta; Ben-Sahra, Issam; Manning, Brendan D.

Cancer Signaling Drives Cancer Metabolism: AKT and the Warburg Effect 癌症信号驱动癌症代谢: AKT和Warburg效应

CANCER RESEARCH

IF16.6

2021-10-01

OAAI

Hosios, Aaron M.; Manning, Brendan D.

James R. Mitchell (1971-2020)

CELL METABOLISM

IF30.9

2021-03-01

OAAI

Ristow, Michael; Lee, Chih-Hao; De Bock, Katrien; Gladyshev, Vadim N.; Hotamisligil, Gokhan S.; Manning, Brendan D.

研究方向