Gary A. Piazza - Publications, H-index & Citations

Gary A. Piazza

Auburn University

52H指数

331论文数

8.5K被引数

收录论文 121

发表时间

Developing a Phosphodiesterase 10A Inhibitor as a Novel Therapeutic Agent for Triple-Negative Breast Cancer 开发一种磷酸二酯酶10A抑制剂作为三阴性乳腺癌的新型治疗剂

Cells

IF5.2

2026-08-06

OAAI

Mrityunjoy Biswas; Md Manirujjaman; Jovanny Zabaleta; Dorota Wyczechowska; Jone Garai; Qingzhao Yu; Luis Del Valle; Samarpan Majumder; Timothy Kayes; Xi Chen; Adam B. Keeton; Lucio Miele; Yulia Y. Maxuitenko; Nan Li; Gary A. Piazza; Fokhrul Hossain

Pan-RAS Inhibitors: Expanding Therapeutic Potential and Evading Resistance 泛-RAS抑制剂：拓展治疗潜力与规避耐药性

Cancers

IF4.4

2026-06-04

OAAI

Sindhu Ramesh; Junwei Wang; Chung-Hui Huang; Austin M. Moore; Khalda Fadlalla; Kristy L. Berry; Yulia Y. Maxuitenko; Xi Chen; Adam B. Keeton; Bassel El-Rayes; Donald J. Buchsbaum; Karim I. Budhwani; Gang Zhou; Amit K. Mitra; Gary A. Piazza

Targeting the NAD+–PARP1–XRCC1 axis in ALS 靶向NAD+–PARP1–XRCC1轴在肌萎缩侧索硬化症中的研究

Trends in Molecular Medicine

IF13.8

2026-05-04

PREAI

Md Ibrahim; Md Shahadat Hossain; Lezanne Ooi; Md Mahmudul Hasan; Shandra Ahsan; Aliasger K. Salem; Gary A. Piazza; Xiaodong Feng; Fakhrul Ahsan

Nerandomilast as the first PDE4B-selective therapy in idiopathic pulmonary fibrosis 奈兰司特作为特发性肺纤维化的第一种PDE4B-selective疗法

Trends in Pharmacological Sciences

IF19.9

2025-12-06

PREAI

Md Ibrahim; Gary A. Piazza; Fakhrul Ahsan

Exploring Dual Inhibitors Carbonic Anhydrases and Phosphodiesterase 5 as Potential Agents for Treatment Alzheimer’s Disease 探索碳酸酐酶和磷酸二酯酶5的双抑制剂作为治疗阿尔茨海默病的潜在药物

European Journal of Medicinal Chemistry

IF5.9

2025-11-28

PREAI

Alessia Costa; Gustavo Provensi; Costanza Titi; Manuela Leri; Monica Bucciantini; Marta Ferraroni; Adam B. Keeton; Austin M. Moore; Gary A. Piazza; Ashraf Hassan Abadi; Andrea Angeli; Claudiu T. Supuran

Preparation and Characterization of Novel Pan-RAS Inhibitor Loaded Ultraflexible Liposomes for the Topical Prevention or Treatment of Skin Melanoma 新型泛RAS抑制剂负载超柔性脂质体的制备与表征：用于皮肤黑色素瘤的局部预防或治疗

Pharmaceutical Research

IF4.3

2025-11-26

PREAI

Shivani A. Dave; Adam B. Keeton; Gary A. Piazza; Anthony J. Di Pasqua

Novel Disulfiram-Loaded Metal–Organic Nanoparticles Inhibit Tumor Growth and Induce Immunogenic Cell Death of Triple-Negative Breast Cancer Cells 新型二硫仑负载金属-有机纳米颗粒抑制三阴性乳腺癌细胞生长并诱导免疫原性细胞死亡

Pharmaceutics 2025, Vol. 17, Page 1448

IF5.5

2025-11-09

OAAI

Chung-Hui Huang; Xuejia Kang; Lang Zhou; Junwei Wang; Shuai Wu; Peizhen Sun; Qi Wang; Adam B. Keeton; Pengyu Chen; Gary A. Piazza

Targeting phosphodiesterase 10 unleashes antitumor immunity by inhibiting the RAS-MAPK signaling in cancer cells and myeloid-derived suppressor cells

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Gazi, Md Yeashin; Okoko, Ogacheko D.; Wang, Xin; Ye, Yan; Fadlalla, Khalda; Chen, Xi; Keeton, Adam; Maxuitenko, Yulia; Shi, Huidong; Piazza, Gary; Zhou, Gang

Evaluation of a Novel Pan-RAS Inhibitor in 3D Bioprinted Tumor Models 评估一种新型泛RAS抑制剂的3D生物打印肿瘤模型

Cancers 2025, Vol. 17, Page 2958

IF0

2025-09-10

OAAI

Daniela D. De Nobrega; Logan C. Eiler; Parmanand Ahirwar; Sonika Nallapu; Urvi P. Rawal; Chelsea L. Crawford; Donald J. Buchsbaum; Adam B. Keeton; Yulia Y. Maxuitenko; Xi Chen; Gary A. Piazza; Allan Tsung; Karim I. Budhwani

ADT-1004: a first-in-class, oral pan-RAS inhibitor with robust antitumor activity in preclinical models of pancreatic ductal adenocarcinoma ADT-1004: 在胰腺导管腺癌的临床前模型中具有强大抗肿瘤活性的一流口服pan-ras抑制剂

MOLECULAR CANCER

IF33.9

2025-03-13

OAAI

Bandi, Dhana Sekhar Reddy; Nagaraju, Ganji Purnachandra; Sarvesh, Sujith; Carstens, Julienne L.; Foote, Jeremy B.; Graff, Emily C.; Fang, Yu-Hua D.; Keeton, Adam B.; Chen, Xi; Valiyaveettil, Jacob; Berry, Kristy L.; Bae, Sejong; Akce, Mehmet; Gorman, Greg; Yoon, Karina J.; Manne, Upender; Boyd, Michael R.; Buchsbaum, Donald J.; Azmi, Asfar S.; Maxuitenko, Yulia Y.; Piazza, Gary A.

A novel PDE10 inhibitor targets cancer cells and MDSC to reverse the immunosuppressive tumor microenvironment: antitumor activity in multiple tumor types

EUROPEAN JOURNAL OF CANCER

IF7.1

2024-10-01

PREAI

Piazza, G.

A novel pan-RAS inhibitor (ADT-1004) with superior efficacy over mutation-specific KRAS inhibitors in mouse models of pancreatic cancer

EUROPEAN JOURNAL OF CANCER

IF7.1

2024-10-01

PREAI

Bandi, D. S. R.; Nagaraju, G. P.; Foote, J. B.; Keeton, A.; Chen, X.; Berry, K. L.; Maxuitenko, Y. Y.; Manne, U.; Buchsbaum, D. J.; Piazza, G. A.; El-Rayes, B. F.

Survival benefit and tumor regression with a dual RAS/β-catenin inhibitor, ADT-030, in murine models of pancreatic and lung cancer

EUROPEAN JOURNAL OF CANCER

IF7.1

2024-10-01

PREAI

Bandi, D. S. R.; Nagaraju, G. P.; Foote, J. B.; Keeton, A.; Chen, X.; Berry, K. L.; Maxuitenko, Y. Y.; Manne, U.; Buchsbaum, D. J.; Piazza, G. A.; El-Rayes, B. F.

A novel pan-RAS/ β-catenin inhibitor, ADT-030, produces tumor regression in PDX models of pancreatic cancer

CANCER RESEARCH

IF16.6

2024-09-15

PREAI

Bandi, Dhana Sekhar Reddy; Nagaraju, Ganji P.; Foote, Jeremy B.; Keeton, Adam B.; Chen, Xi; Berry, Kristy L.; Maxuitenko, Yulia Y.; Manne, Upender; Buchsbaum, Donald J.; Piazza, Gary A.; El-Rayes, Bassel F.

Efficacy advantages of a novel pan-RAS inhibitor, ADT-1004, over mutant- specific KRAS inhibitors for suppressing pancreatic tumor growth in murine models

CANCER RESEARCH

IF16.6

2024-09-15

PREAI

Assessment of KRASG12C inhibitors for colorectal cancer 结直肠癌KRASG12C抑制剂的评估

FRONTIERS IN ONCOLOGY

IF3.3

2024-06-24

OAAI

Piazza, Gary A.; Chandrasekaran, Preethi; Maxuitenko, Yulia Y.; Budhwani, Karim I.

ADT-1004: A promising pan-RAS inhibitor for targeting KRAS mutations in pancreatic ductal adenocarcinoma

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Bandi, Dhana Sekhar Reddy; Ganji, Purnachandra Nagaraju; Sarvesh, Sujith; Maxuitenko, Yulia; Foote, Jeremy B.; Keeton, Adam B.; Chen, Xi; Buchsbaum, Donald; Piazza, Gary; El-Rayes, Bassel

Novel Pan-RAS inhibitor ADT-007: A unique mechanism of antitumor selectivity in pancreatic and colorectal carcinoma models

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Wang, Junwei; Keeton, Adam B.; Ramesh, Sindhu; Johnson, Peyton; Maxuitenko, Yulia Y.; Foote, Jeremy B.; Huang, Chung-Hui; Berry, Kristy L.; Fadlalla, Khalda; Reddy, Bandi D.; Nagaraju, Ganji P.; Nurmemmedov, Elmar; Babic, Ivan; Gaponenko, Vadim; Chen, Xi; El-Rayes, Bassel F.; Buchsbaum, Donald J.; Piazza, Gary A.

ADT-030 is a novel dual-acting RAS/β-catenin inhibitor that potentiates antitumor immunity

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Gazi, Md Yeashin; Okoko, Ogacheko; Wang, Xin; Brandle, Caitlin; Chen, Xi; Fadlalla, Khalda; Keeton, Adam; Maxuitenko, Yulia; Hedrick, Catherine; Shi, Huidong; Piazza, Gary; Zhou, Gang

Efficacy and tolerability of a novel pan-RAS inhibitor with a unique mechanism of selectivity in mouse models of pancreatic cancer

MOLECULAR CANCER THERAPEUTICS

IF5.5

2023-12-01

PREAI

Keeton, Adam B.; Maxuitenko, Yulia Y.; Foote, Jeremy B.; Huang, Chung -Hui; Berry, Kristy L.; Fadlalla, Khalda; Nagaraju, Ganji P.; Reddy, Bandi D. S.; Chen, Xi; El-Rayes, Bassel F.; Buchsbaum, Donald J.; Piazza, Gary A.

研究方向