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C

Conor J. Kearney

olivia newton-john cancer research institute
H指数:27
被引数:3,355

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Death receptors regulate entry to therapy-induced senescence and orchestrate addiction to IAPs

死亡受体调控治疗性衰老的进入并协调对IAPs的依赖

Science Advances
IF12.5
2026-10-230
OAAI
Gokhan Gunay; Seren Hamsici; Vaishnavi Venugopalan; Aoife Costigan; Melanie Fritsch; Aislinn Gallagher Aldave; Anne Huber; Brianna Fernandez; Hande Efe-Cicek; Pavel Davidovich; Pavitha Parathan; Akash Srivaths; Natalie Hudson; Eleanor Noone; Jeffrey O’Callaghan; Lisa A. Mielke; Sarah L. Doyle; Sabrina L. Spencer; Matthew Campbell; Conor J. Kearney; Hamid Kashkar; Seamus J. Martin
A TAK1 cytokine toxicity checkpoint controls anti-cancer immunity

TAK1细胞因子毒性检查点控制抗肿瘤免疫

Cell Reports
IF6.9
2026-01-010
OAAI
Djajawi, Tirta M.; Huber, Anne; Rivera, Sarahi Mendoza; Srivaths, Akash; Salehi, Maede; Gunay, Gokhan; Gerak, Chloe; Neil, Liam; Ozaydin, Oliver; Voulgaris, Olivia; Al Halawani, Aleen; Gannon, Daire; Khoshdoozmasouleh, Nooshin; Jenkins, Laura J.; Chan, Kok Fei; Behren, Andreas; Ernst, Matthias; Mielke, Lisa A.; Lelliott, Emily J.; Dong, Hao; Feltham, Rebecca; Sutton, Vivien R.; Trapani, Joseph A.; Mariadason, John M.; Pal, Bhupinder; Martin, Seamus J.; Vervoort, Stephin J.; Kearney, Conor J.
PRMT1 acts as a suppressor of MHC-I and anti-tumor immunity
CELL REPORTS
IF6.9
2024-03-013
OA
Djajawi, Tirta M.; Pijpers, Lizzy; Srivaths, Akash; Chisanga, David; Chan, Kok Fei; Hogg, Simon J.; Neil, Liam; Rivera, Sarahi Mendoza; Bartonicek, Nenad; Ellis, Sarah L.; Sian, Terry C. C. Lim Kam; Faridi, Pouya; Liao, Yang; Pal, Bhupinder; Behren, Andreas; Shi, Wei; Vervoort, Stephin J.; Johnstone, Ricky W.; Kearney, Conor J.
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity (vol 42, 113014, 2023)
CELL REPORTS
IF6.9
2024-02-010
OA
House, Imran G.; Derrick, Emily B.; Sek, Kevin; Chen, Amanda X. Y.; Li, Jasmine; Lai, Junyun; Todd, Kirsten L.; Munoz, Isabelle; Michie, Jessica; Chan, Cheok Weng; Huang, Yu-Kuan; Chan, Jack D.; Petley, Emma V.; Tong, Junming; Nguyen, Datminh; Engel, Sven; Savas, Peter; Hogg, Simon J.; Vervoort, Stephin J.; Kearney, Conor J.; Burr, Marian L.; Lam, Enid Y. N.; Gilan, Omer; Bedoui, Sammy; Johnstone, Ricky W.; Dawson, Mark A.; Loi, Sherene; Darcy, Phillip K.; Beavis, Paul A.
Rationally designed chimeric PI3K-BET bromodomain inhibitors elicit curative responses in MYC-driven lymphoma

合理设计的嵌合PI3K-BET溴结构域抑制剂在MYC驱动的淋巴瘤中引起治疗反应

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-08-291
OAAI
Oh, Danielle H.; Ma, Xiao; Hogg, Simon J.; He, Jackson; Kearney, Conor; Brasacchio, Daniella; Susanto, Olivia; Maher, Belinda; Jennings, Ian G.; Newbold, Andrea; Fraser, Peter; Gruber, Emily; Kats, Lev M.; Gregory, Gareth P.; Johnstone, Ricky W.; Thompson, Philip E.; Shortt, Jake
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity

CRISPR-Cas9筛选确定了限制CXCL9表达和抗肿瘤免疫的IRF1-SOCS1-mediated负反馈回路

CELL REPORTS
IF6.9
2023-08-016
OA
House, Imran G.; Derrick, Emily B.; Sek, Kevin; Chen, Amanda X. Y.; Li, Jasmine; Lai, Junyun; Todd, Kirsten L.; Munoz, Isabelle; Michie, Jessica; Chan, Cheok Weng; Huang, Yu-Kuan; Chan, Jack D.; Petley, Emma, V; Tong, Junming; Nguyen, DatMinh; Engel, Sven; Savas, Peter; Hogg, Simon J.; Vervoort, Stephin J.; Kearney, Conor J.; Burr, Marian L.; Lam, Enid Y. N.; Gilan, Omer; Bedoui, Sammy; Johnstone, Ricky W.; Dawson, Mark A.; Loi, Sherene; Darcy, Phillip K.; Beavis, Paul A.
Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction
SCIENCE ADVANCES
IF12.5
2022-09-1634
OAAI
Fujihara, Kenji M.; Zhang, Bonnie Z.; Jackson, Thomas D.; Ogunkola, Moses O.; Nijagal, Brunda; Milne, Julia, V; Sallman, David A.; Ang, Ching-Seng; Nikolic, Iva; Kearney, Conor J.; Hogg, Simon J.; Cabalag, Carlos S.; Sutton, Vivien R.; Watt, Sally; Fujihara, Asuka T.; Trapani, Joseph A.; Simpson, Kaylene J.; Stojanovski, Diana; Leimkuhler, Silke; Haupt, Sue; Phillips, Wayne A.; Clemons, Nicholas J.
Distinct modulation of IFNγ-induced transcription by BET bromodomain and catalytic P300/CBP inhibition in breast cancer

乳腺癌中BET溴结构域和催化P300/CBP抑制对ifn γ 诱导的转录的不同调节

CLINICAL EPIGENETICS
IF4.4
2022-07-282
OAAI
Hogg, Simon J.; Motorna, Olga; Kearney, Conor J.; Derrick, Emily B.; House, Imran G.; Todorovski, Izabela; Kelly, Madison J.; Zethoven, Magnus; Bromberg, Kenneth D.; Lai, Albert; Beavis, Paul A.; Shortt, Jake; Johnstone, Ricky W.; Vervoort, Stephin J.
MAIT cells regulate NK cell-mediated tumor immunity

MAIT细胞调节NK细胞介导的肿瘤免疫

NATURE COMMUNICATIONS
IF15.7
2021-08-0648
OAAI
Petley, Emma, V; Koay, Hui-Fern; Henderson, Melissa A.; Sek, Kevin; Todd, Kirsten L.; Keam, Simon P.; Lai, Junyun; House, Imran G.; Li, Jasmine; Zethoven, Magnus; Chen, Amanda X. Y.; Oliver, Amanda J.; Michie, Jessica; Freeman, Andrew J.; Giuffrida, Lauren; Chan, Jack D.; Pizzolla, Angela; Mak, Jeffrey Y. W.; McCulloch, Timothy R.; Souza-Fonseca-Guimaraes, Fernando; Kearney, Conor J.; Millen, Rosemary; Ramsay, Robert G.; Huntington, Nicholas D.; McCluskey, James; Oliaro, Jane; Fairlie, David P.; Neeson, Paul J.; Godfrey, Dale, I; Beavis, Paul A.; Darcy, Phillip K.
CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell Memory

CDK4/6抑制通过诱导T细胞记忆促进抗肿瘤免疫

CANCER DISCOVERY
IF33.3
2021-05-1472
OA
Lelliott, Emily J.; Kong, Isabella Y.; Zethoven, Magnus; Ramsbottom, Kelly M.; Martelotto, Luciano G.; Meyran, Deborah; Zhu, Joe Jiang; Costacurta, Matteo; Kirby, Laura; Sandow, Jarrod J.; Lim, Lydia; Dominguez, Pilar M.; Todorovski, Izabela; Haynes, Nicole M.; Beavis, Paul A.; Neeson, Paul J.; Hawkins, Edwin D.; McArthur, Grant A.; Parish, Ian A.; Johnstone, Ricky W.; Oliaro, Jane; Sheppard, Karen E.; Kearney, Conor J.; Vervoort, Stephin J.
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
MOLECULAR CELL
IF16.6
2021-05-0176
OAAI
Hogg, Simon J.; Motorna, Olga; Cluse, Leonie A.; Johanson, Timothy M.; Coughlan, Hannah D.; Raviram, Ramya; Myers, Robert M.; Costacurta, Matteo; Todorovski, Izabela; Pijpers, Lizzy; Bjelosevic, Stefan; Williams, Tobias; Huskins, Shannon N.; Kearney, Conor J.; Devlin, Jennifer R.; Fan, Zheng; Jabbari, Jafar S.; Martin, Ben P.; Fareh, Mohamed; Kelly, Madison J.; Dupere-Richer, Daphne; Sandow, Jarrod J.; Feran, Breon; Knight, Deborah; Khong, Tiffany; Spencer, Andrew; Harrison, Simon J.; Gregory, Gareth; Wickramasinghe, Vihandha O.; Webb, Andrew, I; Taberlay, Phillippa C.; Bromberg, Kenneth D.; Lai, Albert; Papenfuss, Anthony T.; Smyth, Gordon K.; Allan, Rhys S.; Licht, Jonathan D.; Landau, Dan A.; Abdel-Wahab, Omar; Shortt, Jake; Vervoort, Stephin J.; Johnstone, Ricky W.

研究方向

暂未获取到该数据
S
Stephin J. Vervoort
H 指数:34论文数:152被引数:4,590
J
Jane Oliaro
H 指数:33论文数:121被引数:4,539
R
Ricky W. Johnstone
H 指数:96论文数:780被引数:3.8万
S
Séamus J. Martin
H 指数:90论文数:285被引数:5.8万
J
Jessica Michie
H 指数:10论文数:43被引数:931
K
Kelly M. Ramsbottom
H 指数:20论文数:93被引数:1,724
P
Paul A. Beavis
H 指数:45论文数:272被引数:1.3万
A
Andrew J. Freeman
H 指数:12论文数:38被引数:1,216
S
Simon J. Hogg
H 指数:25论文数:111被引数:3,552
P
Phillip K. Darcy
H 指数:77论文数:537被引数:2.2万