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W

Wilton B. Williams

Duke University School of Medicine
H指数:26
被引数:2,352

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Humans and rhesus macaques share maturation pathways of HIV-1 envelope-reactive V3-glycan bnAb lineages

人类和恒河猴共享HIV-1包膜反应性V3-糖基bnAb谱系的成熟途径

Science Translational Medicine
IF14.6
2026-07-080
PRE
Matthew Clark; Hui Li; Mitchell Martin; Tyler D. Evangelous; Sophie M.-C. Gobeil; Madison Berry; Kshitij Wagh; Elena E. Giorgi; Michael P. Hogarty; Chengyan Zhao; Shuyi Wang; Lorie Marchitto; Wenge Ding; Younghoon Park; Juliette Rando; John Carey; Andrew J. Connell; Ashwin N. Skelly; Yue Chen; Seth Rohr; Samantha Balgobin; Chuancang Jiang; Sravani Venkatayogi; Katayoun Mansouri; Robert J. Edwards; Jared Lindenberger; Bhavna Hora; Nicole Doria-Rose; John Mascola; Marit J. van Gils; Rogier W. Sanders; Bette Korber; Beatrice Hahn; Kevin O. Saunders; Priyamvada Acharya; Kevin Wiehe; Barton F. Haynes; George M. Shaw; Wilton B. Williams
Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development

Env-antibody共进化识别B细胞初始为HIV V2顶点广谱中和抗体发展的主要瓶颈

Science Immunology
IF16.3
2026-02-130
PRE
Rumi Habib; Ryan S. Roark; Hui Li; Andrew Jesse Connell; Michael P. Hogarty; Kshitij Wagh; Shuyi Wang; Lorie Marchitto; Ashwin N. Skelly; John W. Carey; Kirsten J. Sowers; Kasirajan Ayyanathan; Samantha J. Plante; Frederic Bibollet-Ruche; Younghoon Park; Colby J. Agostino; Ajay Singh; Christian L. Martella; Emily Lewis; Juliette M. Rando; Neha Chohan; Jinery Lora; Wenge Ding; Mary S. Campion; Chengyan Zhao; Weimin Liu; Yingying Li; Xuduo Li; Bo Liang; Rohan Roy Chowdhury; Khaled Amereh; Elizabeth Van Itallie; Zizhang Sheng; Amrit R. Ghosh; Katharine J. Bar; Wilton B. Williams; Kevin Wiehe; Kevin O. Saunders; Robert J. Edwards; Derek W. Cain; Mark G. Lewis; Facundo D. Batista; Dennis R. Burton; Raiees Andrabi; Daniel W. Kulp; Barton F. Haynes; Bette Korber; Lawrence Shapiro; Peter D. Kwong; Beatrice H. Hahn; George M. Shaw
Mechanisms of early-life immunity associated with induction of heterologous HIV-1 neutralizing antibodies
JOURNAL OF IMMUNOLOGY
IF3.4
2025-11-010
PRE
Holmes, Sommer; Li, Hui; Shen, Shaunna; Martin, Mitchell; Tuck, Ryan; Chen, Yue; Giorgi, Elena; Kirshner, Helene; Berry, Madison; Van Italie, Elizabeth; Venkatayogi, Sravani; Beem, Josh; Edwards, Robert; Mansouri, Katayoun; Denayer, Nicole; Demarco, Todd; Denny, Thomas; Kuykendall, Cindy; Gurley, Thaddeus; Moody, Anthony; Wang, Yunfei; Evangelous, Tyler; Clinton, John; Hora, Bhavna; Wagh, Kshitij; Seaman, Michael; Saunders, Kevin; Solomotis, Nicholas; Misamore, Johnathan; Lewis, Mark; Wiehe, Kevin; Montefiori, David; Shaw, George; Williams, Wilton
Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans

疫苗诱导异源HIV-1中和抗体B细胞谱系在人类中

Cell
IF42.5
2025-11-010
OAAI
Wilton B. Williams; S. Munir Alam; Gilad Ofek; Nathaniel Erdmann; David C. Montefiori; Michael S. Seaman; Kshitij Wagh; Bette Korber; Robert J. Edwards; Katayoun Mansouri; Amanda Eaton; Derek W. Cain; Mitchell Martin; JongIn Hwang; Aria Arus-Altuz; Xiaozhi Lu; Fangping Cai; Nolan Jamieson; Robert Parks; Maggie Barr; Andrew Foulger; Kara Anasti; Parth Patel; Salam Sammour; Ruth J. Parsons; Xiao Huang; Jared Lindenberger; Susan Fetics; Katarzyna Janowska; Aurelie Niyongabo; Benjamin M. Janus; Anagh Astavans; Christopher B. Fox; Ipsita Mohanty; Tyler Evangelous; Yue Chen; Madison Berry; Helene Kirshner; Elizabeth Van Itallie; Kevin O. Saunders; Kevin Wiehe; Kristen W. Cohen; M. Juliana McElrath; Lawrence Corey; Priyamvada Acharya; Stephen R. Walsh; Lindsey R. Baden; Barton F. Haynes
Acquisition of quaternary trimer interaction as a key step in the lineage maturation of a broad and potent HIV-1 neutralizing antibody

四聚体三聚体相互作用的形成作为广谱强效HIV-1中和抗体谱系成熟过程中的关键步骤

Structure
IF4.3
2025-05-230
PRE
Qingbo Liu; Ruth J. Parsons; Kevin Wiehe; Robert J. Edwards; Kevin O. Saunders; Peng Zhang; Huiyi Miao; Kedamawit Tilahun; Julia Jones; Yue Chen; Bhavna Hora; Wilton B. Williams; David Easterhoff; Xiao Huang; Katarzyna Janowska; Katayoun Mansouri; Barton F. Haynes; Priyamvada Acharya; Paolo Lusso
Neonatal immunity associated with heterologous HIV-1 neutralizing antibody induction in SHIV-infected Rhesus Macaques
NATURE COMMUNICATIONS
IF15.7
2024-11-270
OAAI
Holmes, Sommer; Li, Hui; Shen, Xiaoying; Martin, Mitchell; Tuck, Ryan; Chen, Yue; Giorgi, Elena E.; Kirshner, Helene Fradin; Berry, Madison; Van Italie, Elizabeth; Venkatayogi, Sravani; Beem, Joshua S. Martin; Edwards, Robert J.; Mansouri, Katayoun; Singh, Ajay; Kuykendall, Cindy; Gurley, Thaddeus; Moody, M. Anthony; Denayer, Nicole; Demarco, Todd; Denny, Thomas N.; Wang, Yunfei; Evangelous, Tyler D.; Clinton, John T.; Hora, Bhavna; Wagh, Kshitij; Seaman, Michael S.; Saunders, Kevin O.; Solomotis, Nicholas; Misamore, Johnathan; Lewis, Mark G.; Wiehe, Kevin; Montefiori, David C.; Shaw, George M.; Williams, Wilton B.
Immunization with germ line-targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques
SCIENCE IMMUNOLOGY
IF16.3
2024-08-301
PRE
Nelson, Ashley N.; Shen, Xiaoying; Vekatayogi, Sravani; Zhang, Shiyu; Ozorowski, Gabriel; Dennis, Maria; Sewall, Leigh M.; Milligan, Emma; Davis, Dominique; Cross, Kaitlyn A.; Chen, Yue; van Schooten, Jelle; Eudailey, Joshua; Isaac, John; Memon, Saad; Weinbaum, Carolyn; Gao, Hongmei; Stanfield-Oakley, Sherry; Byrd, Alliyah; Chutkan, Suni; Berendam, Stella; Cronin, Kenneth; Yasmeen, Anila; Alam, Munir; Labranche, Celia C.; Rogers, Kenneth; Shirreff, Lisa; Cupo, Albert; Derking, Ronald; Villinger, Francois; Klasse, Per Johan; Ferrari, Guido; Williams, Wilton B.; Hudgens, Michael G.; Ward, Andrew B.; Montefiori, David C.; Van Rompay, Koen K. A.; Wiehe, Kevin; Moore, John P.; Sanders, Rogier W.; De Paris, Kristina; Permar, Sallie R.
SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition
MOLECULAR CELL
IF16.6
2024-07-010
OAAI
Zhang, Qianyi E.; Lindenberger, Jared; Parsons, Ruth J.; Thakur, Bhishem; Parks, Rob; Park, Chan Soo; Huang, Xiao; Sammour, Salam; Janowska, Katarzyna; Spence, Taylor N.; Edwards, Robert J.; Martin, Mitchell; Williams, Wilton B.; Gobeil, Sophie; Montefiori, David C.; Korber, Bette; Saunders, Kevin O.; Haynes, Barton F.; Henderson, Rory; Acharya, Priyamvada
Host immunity associated with spontaneous suppression of viremia in therapy-naIve young rhesus macaques following neonatal SHIV infection
JOURNAL OF VIROLOGY
IF3.8
2023-11-302
OAAI
Evangelous, Tyler D.; Berry, Madison; Venkatayogi, Sravani; LeMaster, Cas; Geanes, Eric S.; De Naeyer, Nicole; DeMarco, Todd; Shen, Xiaoying; Li, Hui; Hora, Bhavna; Solomonis, Nicholas; Misamore, Johnathan; Lewis, Mark G.; Denny, Thomas N.; Montefiori, David; Shaw, George M.; Wiehe, Kevin; Bradley, Todd; Williams, Wilton B.
Neonatal SHIV infection in rhesus macaques elicited heterologous HIV-1-neutralizing antibodies
CELL REPORTS
IF6.9
2023-03-014
OAAI
Hora, Bhavna; Li, Hui; Shen, Xiaoying; Martin, Mitchell; Chen, Yue; Berry, Madison; Evangelous, Tyler; Macintyre, Andrew N.; Arus-Altuz, Aria; Wang, Shuyi; Singh, Ajay; Zhao, Chengyan; De Naeyer, Nicole; DeMarco, Todd; Kuykendall, Cindy; Gurley, Thaddeus; Saunders, Kevin O.; Denny, Thomas; Moody, M. Anthony; Misamore, John; Lewis, Mark G.; Wiehe, Kevin; Cain, Derek W.; Montefiori, David C.; Shaw, George M.; Williams, Wilton B.
Stabilized HIV-1 envelope immunization induces neutralizing antibodies to the CD4bs and protects macaques against mucosal infection
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-09-0718
OA
Saunders, Kevin O.; Edwards, Robert J.; Tilahun, Kedamawit; Manne, Kartik; Lu, Xiaozhi; Cain, Derek W.; Wiehe, Kevin; Williams, Wilton B.; Mansouri, Katayoun; Hernandez, Giovanna E.; Sutherland, Laura; Scearce, Richard; Parks, Robert; Barr, Maggie; DeMarco, Todd; Eater, Chloe M.; Eaton, Amanda; Morton, Georgeanna; Mildenberg, Benjamin; Wang, Yunfei; Rountree, R. Wes; Tomai, Mark A.; Fox, Christopher B.; Moody, M. Anthony; Alam, S. Munir; Santra, Sampa; Lewis, Mark G.; Denny, Thomas N.; Shaw, George M.; Montefiori, David C.; Acharya, Priyamvada; Haynes, Barton F.
Cryo-EM structures of SARS-CoV-2 Omicron BA.2 spike
CELL REPORTS
IF6.9
2022-06-0164
OAAI
Stalls, Victoria; Lindenberger, Jared; Gobeil, Sophie M. -C.; Henderson, Rory; Parks, Rob; Barr, Maggie; Deyton, Margaret; Martin, Mitchell; Janowska, Katarzyna; Huang, Xiao; May, Aaron; Speakman, Micah; Beaudoin, Esther; Kraft, Bryan; Lu, Xiaozhi; Edwards, Robert J.; Eaton, Amanda; Montefiori, David C.; Williams, Wilton B.; Saunders, Kevin O.; Wiehe, Kevin; Haynes, Barton F.; Acharya, Priyamvada
Structural diversity of the SARS-CoV-2 Omicron spike
MOLECULAR CELL
IF16.6
2022-06-01124
OAAI
Gobeil, Sophie M-C; Henderson, Rory; Stalls, Victoria; Janowska, Katarzyna; Huang, Xiao; May, Aaron; Speakman, Micah; Beaudoin, Esther; Manne, Kartik; Li, Dapeng; Parks, Rob; Barr, Maggie; Deyton, Margaret; Martin, Mitchell; Mansouri, Katayoun; Edwards, Robert J.; Eaton, Amanda; Montefiori, David C.; Sempowski, Gregory D.; Saunders, Kevin O.; Wiehe, Kevin; Williams, Wilton; Korber, Bette; Haynes, Barton F.; Acharya, Priyamvada
mRNA-encoded HIV-1 Env trimer ferritin nanoparticles induce monoclonal antibodies that neutralize heterologous HIV-1 isolates in mice
CELL REPORTS
IF6.9
2022-03-0136
OAAI
Mu, Zekun; Wiehe, Kevin; Saunders, Kevin O.; Henderson, Rory; Cain, Derek W.; Parks, Robert; Martik, Diana; Mansouri, Katayoun; Edwards, Robert J.; Newman, Amanda; Lu, Xiaozhi; Shi-Mao Xia; Eaton, Amanda; Bonsignori, Mattia; Montefiori, David; Han, Qifeng; Venkatayogi, Sravani; Evangelous, Tyler; Wang, Yunfei; Rountree, Wes; Korber, Bette; Wagh, Kshitij; Tam, Ying; Barbosa, Christopher; Alam, S. Munir; Williams, Wilton B.; Tian, Ming; Alt, Frederick W.; Pardi, Norbert; Weissman, Drew; Haynes, Barton F.
Cold sensitivity of the SARS-CoV-2 spike ectodomain
NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2021-01-0552
OAAI
Edwards, Robert J.; Mansouri, Katayoun; Stalls, Victoria; Manne, Kartik; Watts, Brian; Parks, Rob; Janowska, Katarzyna; Gobeil, Sophie M. C.; Kopp, Megan; Li, Dapeng; Lu, Xiaozhi; Mu, Zekun; Deyton, Margaret; Oguin, Thomas H.; Sprenz, Jordan; Williams, Wilton; Saunders, Kevin; Montefiori, David; Sempowski, Gregory D.; Henderson, Rory; Alam, Munir; Haynes, Barton F.; Acharya, Priyamvada
Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge
CELL REPORTS
IF6.9
2020-05-0142
OAAI
Felber, Barbara K.; Lu, Zhongyan; Hu, Xintao; Valentin, Antonio; Rosati, Margherita; Remmel, Christopher A. L.; Weiner, Joshua A.; Carpenter, Margaret C.; Faircloth, Katelyn; Stanfield-Oakley, Sherry; Williams, Wilton B.; Shen, Xiaoying; Tomaras, Georgia D.; LaBranche, Celia C.; Montefiori, David; Trinh, Hung, V; Rao, Mangala; Alam, Munir S.; Vandergrift, Nathan A.; Saunders, Kevin O.; Wang, Yunfei; Rountree, Wes; Das, Jishnu; Alter, Galit; Reed, Steven G.; Aye, Pyone P.; Schiro, Faith; Pahar, Bapi; Dufour, Jason P.; Veazey, Ronald S.; Marx, Preston A.; Venzon, David J.; Shaw, George M.; Ferrari, Guido; Ackerman, Margaret E.; Haynes, Barton F.; Pavlakis, George N.
Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization
CELL REPORTS
IF6.9
2020-02-0119
OAAI
Han, Qifeng; Bradley, Todd; Williams, Wilton B.; Cain, Derek W.; Montefiori, David C.; Saunders, Kevin O.; Parks, Robert J.; Edwards, Regina W.; Ferrari, Guido; Mueller, Olaf; Shen, Xiaoying; Wiehe, Kevin J.; Reed, Steven; Fox, Christopher B.; Rountree, Wes; Vandergrift, Nathan A.; Wang, Yunfei; Sutherland, Laura L.; Santra, Sampa; Moody, M. Anthony; Permar, Sallie R.; Tomaras, Georgia D.; Lewis, Mark G.; Van Rompay, Koen K. A.; Haynes, Barton F.
Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies (vol 15, e1008026, 2019)
PLOS PATHOGENS
IF4.9
2019-12-020
OAAI
LaBranche, Celia C.; Henderson, Rory; Hsu, Allen; Behrens, Shay; Chen, Xuejun; Zhou, Tongqing; Wiehe, Kevin; Saunders, Kevin O.; Alam, S. Munir; Bonsignori, Mattia; Borgnia, Mario J.; Sattentau, Quentin J.; Eaton, Amanda; Greene, Kelli; Gao, Hongmei; Liao, Hua-Xin; Williams, Wilton B.; Peacock, James; Tang, Haili; Perez, Lautaro G.; Edwards, Robert J.; Kepler, Thomas B.; Korber, Bette T.; Kwong, Peter D.; Mascola, John R.; Acharya, Priyamvada; Haynes, Barton F.; Montefiori, David C.

研究方向

暂未获取到该数据
K
Kevin O. Saunders
H 指数:50论文数:210被引数:9,686
D
David C. Montefiori
H 指数:142论文数:1,161被引数:8.6万
K
Kevin Wiehe
H 指数:44论文数:166被引数:9,721
B
Barton F. Haynes
H 指数:144论文数:834被引数:7.7万
R
Robert J. Edwards
H 指数:51论文数:224被引数:8,417
P
Priyamvada Acharya
H 指数:49论文数:222被引数:1.0万
G
George M. Shaw
H 指数:121论文数:399被引数:5.5万
B
Bette Korber
H 指数:131论文数:519被引数:5.9万
K
Katayoun Mansouri
H 指数:28论文数:78被引数:4,142
S
S. Munir Alam
H 指数:73论文数:233被引数:1.9万