Zihuan Yang

Department of Orthopedics

H指数:26

被引数:1,641

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Succinate exacerbates obesity-associated osteoarthritis: mitochondrial dysfunction mediated by SUCNR1 activation and succinylation modification

琥珀酸盐加剧肥胖相关性骨关节炎：由SUCNR1激活和琥珀酰化修饰介导的线粒体功能障碍

Cell Death Discovery

IF7

2026-08-220

Multi-scale Engineering of Biodegradable Zn-Mg Interbody Cages for Stronger, Faster Spinal Fusion

多尺度工程化可生物降解Zn-Mg椎间融合器用于更强、更快的脊柱融合

Biomaterials

IF12.9

2026-08-100

PRE

Osteoblast-derived CTGF contributes to detrimental bone-cartilage crosstalk via EGFR/ NF-κB signaling pathway in estrogen-deficiency-induced osteoarthritis

成骨细胞来源的CTGF通过EGFR/NF-κB信号通路参与雌激素缺乏性骨关节炎中骨-软骨有害的串扰

Journal of Advanced Research

IF13

2026-07-240

OAAI

Vertebral BMSC-EVs under estrogen deficiency drive senescence-related mitochondrial dysfunction in endplate chondrocytes via MRPL1 mRNA delivery

雌激素缺乏条件下，椎体BMSC-EVs通过MRPL1 mRNA的递送驱动终板软骨细胞的衰老相关线粒体功能障碍

Experimental and Molecular Medicine

IF12.9

2026-05-010

PRE

Targeting SIRT2 induces MLH1 deficiency and boosts antitumor immunity in preclinical colorectal cancer models

靶向SIRT2诱导MLH1缺乏并增强抗肿瘤免疫，在结直肠癌临床前模型中。

Science Translational Medicine

IF14.6

2025-07-160

PRE

Osteoclast-secreted galectin-3 promotes articular cartilage degeneration in OVX rats via LRP1/beta-catenin axis

破骨细胞分泌的galectin-3通过LRP1/beta-catenin轴促进OVX大鼠关节软骨退化。

Osteoarthritis and Cartilage

IF9

2025-07-010

PRE

CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer

NATURE COMMUNICATIONS

IF15.7

2024-06-293

OAAI

Tumor derived exosomal ENTPD2 impair CD8+ T cell function in colon cancer through ATP-adenosine metabolism reprogramming

肿瘤源性外泌体ENTPD2通过ATP-腺苷代谢重编程损害结肠癌CD8 T细胞功能

CELL COMMUNICATION AND SIGNALING

IF8.9

2024-05-166

OAAI

Discovery of Kinetin in inhibiting colorectal cancer progression via enhancing PSMB1-mediated RAB34 degradation

CANCER LETTERS

IF10.1

2024-03-012

OAAI

Aquaporin 9 is involved in CRC metastasis through DVL2-dependent Wnt/β-catenin signaling activation

GASTROENTEROLOGY REPORT

IF4.2

2023-06-224

OAAI

HTRA1 from OVX rat osteoclasts causes detrimental effects on endplate chondrocytes through NF-κB

来自OVX大鼠破骨细胞的HTRA1通过nf-κb对终板软骨细胞产生不利影响

HELIYON

IF3.6

2023-06-012

OAAI

High-throughput proteomics profiling-derived signature associated with chemotherapy response and survival for stage II/III colorectal cancer

NPJ PRECISION ONCOLOGY

IF8

2023-05-312

OAAI

Associations of Homocysteine, Folate, and Vitamin B12 with Osteoarthritis: A Mendelian Randomization Study

NUTRIENTS

IF5

2023-03-2816

OAAI

Distinct pathological changes of osteochondral units in early OVX-OA involving TGF-β signaling

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2022-12-156

OAAI

VAERHNN: Voting-averaged ensemble regression and hybrid neural network to investigate potent leads against colorectal cancer

KNOWLEDGE-BASED SYSTEMS

IF7.6

2022-12-0110

PRE

CTGF as a multifunctional molecule for cartilage and a potential drug for osteoarthritis

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2022-10-1718

OAAI

Inhibition of the PLK1-Coupled Cell Cycle Machinery Overcomes Resistance to Oxaliplatin in Colorectal Cancer

抑制PLK1-Coupled细胞周期机制可克服结直肠癌对奥沙利铂的耐药性

ADVANCED SCIENCE

IF14.1

2021-10-2843

Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer

NATURE COMMUNICATIONS

IF15.7

2021-07-2172

OAAI

Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis

CANCER CELL INTERNATIONAL

IF6

2021-05-3111

OAAI

Ubiquitin ligase TRIM65 promotes colorectal cancer metastasis by targeting ARHGAP35 for protein degradation

ONCOGENE

IF7.3

2019-07-2252

OAAI

Zihuan Yang

个人简介

教育背景

工作经历

荣誉奖项

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