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N

Nils Blüthgen

Charité - Universitätsmedizin Berlin

52H指数
231论文数
1.5W被引数
收录论文 93
发表时间
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Perturb-seq reveals TCF7 as a transcriptional link between MAPK- and Wnt-driven gene expressionPerturb-seq揭示TCF7是介导MAPK-和Wnt-驱动的基因表达之间的转录连接
errNucleic Acids Research
IF13.1
err2026-07-29
err0
errOAAI
errGhanem El Kassem; Anja Sieber; Bertram Klinger; Florian Uhlitz; David Steinbrecht; Mirjam van Bentum; Shawez Khan; Jasmine Hillmer; Jennifer von Schlichting; Reinhold Schäfer; Nils Blüthgen; Michael Boettcher
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Early neutrophil infiltration promotes TRIMELVax-induced antitumor immunity by linking local inflammation to tumor control早期中性粒细胞浸润通过连接局部炎症与肿瘤控制促进TRIMELVax诱导的抗肿瘤免疫
errOncoImmunology
IF6.3
err2026-06-25
err0
errOAAI
errAmarilis Pérez-Baños; María Alejandra Gleisner; Andrés Tittarelli; Daniela Tapia; María Elisa Cuevas; Antonia Mardonez; Fabián Tempio; Rosario Astaburuaga-García; Iván Flores; Cristian Pereda; Álvaro Lladser; Fermín E. González; Sebastián Valenzuela; Micaela Ricca; María Inés Becker; Nils Blüthgen; Adnane Achour; Flavio Salazar-Onfray
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Elimination of CDX2 restricts intestinal hybrid differentiation signatures in stem cell-derived hepatocyte-like cells消除CDX2限制了干细胞来源的肝样细胞中的肠道杂交分化特征
errStem Cell Research & Therapy
IF7.3
err2025-10-09
err0
errOAAI
errPatrick Nell; Antonia Thomitzek; David Feuerborn; Andreas Scholtz-Illigens; Sarah M. Seidel; Katharina Derksen; Lara Maria Chilinski; Kathrin Kattler-Lackes; Nils Blüthgen; Markus Morkel; Jörn Walter; Karolina Edlund; Jörg Rahnenführer; Jan G. Hengstler
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Rewired type I IFN signaling is linked to age-dependent differences in COVID-19重编程的I型IFN信号与年龄依赖性的COVID-19差异相关
errCell Reports Medicine
IF10.6
err2025-08-19
err0
errOAAI
errLev Petrov; Sophia Brumhard; Sebastian Wisniewski; Philipp Georg; David Hillus; Anna Hiller; Rosario Astaburuaga-García; Nils Blüthgen; Emanuel Wyler; Katrin Vogt; Hannah-Philine Dey; Saskia von Stillfried; Christina Iwert; Roman D. Bülow; Bruno Märkl; Lukas Maas; Christine Langner; Tim Meyer; Jennifer Loske; Roland Eils; Irina Lehmann; Benjamin Ondruschka; Markus Ralser; Jakob Trimpert; Peter Boor; Sammy Bedoui; Christian Meisel; Marcus A. Mall; Victor M. Corman; Leif Erik Sander; Jobst Röhmel; Birgit Sawitzki
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Reporter-based screening identifies RAS-RAF mutations as drivers of resistance to active-state RAS inhibitors in colorectal cancer报告基因筛选鉴定出RAS-RAF突变是结肠癌中对活化状态RAS抑制剂产生耐药性的驱动因素。
errScience Signaling
IF6.6
err2025-07-22
err0
PREAI
errOleksandra Aust; Moritz R. T. Thiel; Eric Blanc; Mareen Lüthen; Viola Hollek; Rosario Astaburuaga-García; Bertram Klinger; Francisca Böhning; Alexandra Trinks; Dieter Beule; Björn Papke; David Horst; Nils Blüthgen; Christine Sers; Channing J. Der; Markus Morkel
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Spike-in enhanced phosphoproteomics uncovers synergistic signaling responses to MEK inhibition in colon cancer cellsSpike-in增强型磷酸化蛋白质组学揭示了结肠癌细胞中MEK抑制的协同信号反应
errNATURE COMMUNICATIONS
IF15.7
err2025-05-27
err0
errOAAI
errvan Bentum, Mirjam; Klinger, Bertram; Sieber, Anja; Naghiloo, Sheyda; Zauber, Henrik; Lehmann, Nadine; Haji, Mohamed; Niquet, Sylvia; Mertins, Philipp; Bluethgen, Nils; Selbach, Matthias
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Subcellular mRNA kinetic modeling reveals nuclear retention as rate-limiting
errMOLECULAR SYSTEMS BIOLOGY
IF7.7
err2024-11-15
err0
errOAAI
errSteinbrecht, David; Minia, Igor; Milek, Miha; Meisig, Johannes; Bluethgen, Nils; Landthaler, Markus
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High-confidence calling of normal epithelial cells allows identification of a novel stem-like cell state in the colorectal cancer microenvironment
errINTERNATIONAL JOURNAL OF CANCER
IF4.7
err2024-07-19
err2
errOAAI
errWei, Tzu-Ting; Blanc, Eric; Peidli, Stefan; Bischoff, Philip; Trinks, Alexandra; Horst, David; Sers, Christine; Bluethgen, Nils; Beule, Dieter; Morkel, Markus; Obermayer, Benedikt
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Network switches and their role in circadian clocks网络交换机及其在生物钟中的作用
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-05-01
err4
errOAAI
errdel Olmo, Marta; Legewie, Stefan; Brunner, Michael; Hoefer, Thomas; Kramer, Achim; Bluethgen, Nils; Herzel, Hanspeter
err分享
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scPerturb: harmonized single-cell perturbation datascPerturb: 协调的单细胞扰动数据
errNATURE METHODS
IF32.1
err2024-01-26
err15
errOAAI
errPeidli, Stefan; Green, Tessa D.; Shen, Ciyue; Gross, Torsten; Min, Joseph; Garda, Samuele; Yuan, Bo; Schumacher, Linus J.; Taylor-King, Jake P.; Marks, Debora S.; Luna, Augustin; Bluethgen, Nils; Sander, Chris
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Combination of tumor asphericity and an extracellular matrix-related prognostic gene signature in non-small cell lung cancer patients
errSCIENTIFIC REPORTS
IF3.9
err2023-11-27
err0
errOAAI
errZschaeck, Sebastian; Klinger, Bertram; van den Hoff, Joerg; Cegla, Paulina; Apostolova, Ivayla; Kreissl, Michael C.; Cholewinski, Witold; Kukuk, Emily; Strobel, Helen; Amthauer, Holger; Bluethgen, Nils; Zips, Daniel; Hofheinz, Frank
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Modeling unveils sex differences of signaling networks in mouse embryonic stem cells
errMOLECULAR SYSTEMS BIOLOGY
IF7.7
err2023-09-21
err1
errOAAI
errSultana, Zeba; Dorel, Mathurin; Klinger, Bertram; Sieber, Anja; Dunkel, Ilona; Bluethgen, Nils; Schulz, Edda G.
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err收藏
Oncogenic signaling is coupled to colorectal cancer cell differentiation state
errJOURNAL OF CELL BIOLOGY
IF6.4
err2023-04-05
err3
errOAAI
errSell, Thomas; Klotz, Christian; Fischer, Matthias M.; Astaburuaga-Garcia, Rosario; Krug, Susanne; Drost, Jarno; Clevers, Hans; Sers, Christine; Morkel, Markus; Bluethgen, Nils
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Modeling the effects of niche specific microenvironmental changes on patient-derived organoids
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errvon Schlichting, Jennifer; Peidli, Stefan; Morkel, Markus; Bluthgen, Nils; Simon, Leona
err分享
err收藏
Single-cell gene regulatory network prediction by explainable AI基于可解释AI的单细胞基因调控网络预测
errNUCLEIC ACIDS RESEARCH
IF13.1
err2023-01-11
err20
errOAAI
errKeyl, Philipp; Bischoff, Philip; Dernbach, Gabriel; Bockmayr, Michael; Fritz, Rebecca; Horst, David; Bluethgen, Nils; Montavon, Gregoire; Mueller, Klaus-Robert; Klauschen, Frederick
err分享
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Identification of an FXR-modulated liver-intestine hybrid state in iPSC-derived hepatocyte-like cells
errJOURNAL OF HEPATOLOGY
IF33
err2022-11-01
err7
errOAAI
errNell, Patrick; Kattler, Kathrin; Feuerborn, David; Hellwig, Birte; Rieck, Adrian; Salhab, Abdulrahman; Lepikhov, Konstantin; Gasparoni, Gilles; Thomitzek, Antonia; Belgasmi, Katharina; Bluethgen, Nils; Morkel, Markus; Kueppers-Munther, Barbara; Godoy, Patricio; Hay, David C.; Cadenas, Cristina; Marchan, Rosemarie; Vartak, Nachiket; Edlund, Karolina; Rahnenfuehrer, Joerg; Walter, Joern; Hengstler, Jan G.
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High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation
errCELLS
IF5.2
err2022-10-27
err5
errOAAI
errSeidel, Florian; Cherianidou, Anna; Kappenberg, Franziska; Marta, Miriam; Dreser, Nadine; Blum, Jonathan; Waldmann, Tanja; Bluthgen, Nils; Meisig, Johannes; Madjar, Katrin; Henry, Margit; Rotshteyn, Tamara; Scholtz-Illigens, Andreas; Marchan, Rosemarie; Edlund, Karolina; Leist, Marcel; Rahnenfuehrer, Joerg; Sachinidis, Agapios; Hengstler, Jan Georg
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Helicobacter pylori shows tropism to gastric differentiated pit cells dependent on urea chemotaxis
errNATURE COMMUNICATIONS
IF15.7
err2022-10-05
err21
errOAAI
errAguilar, Carmen; Pauzuolis, Mindaugas; Pompaiah, Malvika; Vafadarnejad, Ehsan; Arampatzi, Panagiota; Fischer, Mara; Narres, Dominik; Neyazi, Mastura; Kayisoglu, Ozge; Sell, Thomas; Bluethgen, Nils; Morkel, Markus; Wiegering, Armin; Germer, Christoph-Thomas; Kircher, Stefan; Rosenwald, Andreas; Saliba, Antoine-Emmanuel; Bartfeld, Sina
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Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cellsALK信号通路中的突变赋予对ALK抑制剂治疗的抗性，导致神经母细胞瘤细胞的附带脆弱性
errMOLECULAR CANCER
IF33.9
err2022-06-10
err26
errOAAI
errBerlak, Mareike; Tucker, Elizabeth; Dorel, Mathurin; Winkler, Annika; McGearey, Aleixandria; Rodriguez-Fos, Elias; da Costa, Barbara Martins; Barker, Karen; Fyle, Elicia; Calton, Elizabeth; Eising, Selma; Ober, Kim; Hughes, Deborah; Koutroumanidou, Eleni; Carter, Paul; Stankunaite, Reda; Proszek, Paula; Jain, Neha; Rosswog, Carolina; Dorado-Garcia, Heathcliff; Molenaar, Jan Jasper; Hubank, Mike; Barone, Giuseppe; Anderson, John; Lang, Peter; Deubzer, Hedwig Elisabeth; Kuenkele, Annette; Fischer, Matthias; Eggert, Angelika; Kloft, Charlotte; Henssen, Anton George; Boettcher, Michael; Hertwig, Falk; Bluthgen, Nils; Chesler, Louis; Schulte, Johannes Hubertus
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A 3D gene expression atlas of the floral meristem based on spatial reconstruction of single nucleus RNA sequencing data
errNATURE COMMUNICATIONS
IF15.7
err2022-05-20
err34
errOAAI
errNeumann, Manuel; Xu, Xiaocai; Smaczniak, Cezary; Schumacher, Julia; Yan, Wenhao; Bluethgen, Nils; Greb, Thomas; Joensson, Henrik; Traas, Jan; Kaufmann, Kerstin; Muino, Jose M.
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研究方向

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