Jiyong Hong

Duke University

H指数:37

被引数:4,476

个人简介

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A cholinergic hub in the nucleus accumbens gates opioid-reward learning

伏隔核中的胆碱能中枢调控阿片类药物介导的奖赏学习

Nature

IF48.5

2026-08-050

PRE

A general one-step protocol to generate impermeable fluorescent HaloTag substrates for in situ live cell application and super-resolution imaging

一种通用的一步法方案，用于生成适用于原位活细胞应用和超分辨率成像的不透性荧光HaloTag底物

Nature Communications

IF15.7

2026-01-120

OAAI

From Obscurity to Opportunity: LpxH Emerges as a Promising Antibiotic Target in the Battle against Gram-Negative Pathogens

从无名到机遇：LpxH 在对抗革兰氏阴性病原体的战斗中脱颖而出，成为有前途的抗生素靶点

ACS Infectious Diseases

IF3.8

2025-10-270

PRE

Asymmetric Total Synthesis of Daucane-Type Sesquiterpenoids (+)-Ferutinin and (+)-Kuhistanicaol G

不对称全合成达卡内型倍半萜(+)-Ferutinin和(+)-Kuhistanicaol G

ORGANIC LETTERS

IF5

2025-09-010

PRE

Asymmetric Total Synthesis of 4; 9; 10-Trihydroxyguaia-11(13)en-12; 6-olide and Discovery of Its Anticancer Activity against Atypical Teratoid Rhabdoid Tumor

不对称全合成4；9；10-三羟基桉叶-11(13)烯-12；6-内酯及其对不典型畸胎样横纹肌样瘤抗癌活性的发现

ACS Central Science

IF10.4

2025-06-030

Design and Evaluation of Pyridinyl Sulfonyl Piperazine LpxH Inhibitors with Potent Antibiotic Activity Against Enterobacterales

JACS AU

IF8.7

2024-11-110

OAAI

Understanding and targeting fatty acid CoA ligase ACSL4 in human prostate cancer

CANCER RESEARCH

IF16.6

2024-03-220

PRE

Enhanced fungal specificity and in vivo therapeutic efficacy of a C-22-modified FK520 analog against C. neoformans

MBIO

IF4.7

2023-10-312

OAAI

Psymberin, a marine-derived natural product, induces cancer cell growth arrest and protein translation inhibition (vol 9, 999004, 2022)

FRONTIERS IN MEDICINE

IF3

2023-05-311

OAAI

Development of LpxH Inhibitors Chelating the Active Site Dimanganese Metal Cluster of LpxH

CHEMMEDCHEM

IF3.4

2023-04-177

PRE

Manassantin A inhibits tumour growth under hypoxia through the activation of chaperone-mediated autophagy by modulating Hsp90 activity

BRITISH JOURNAL OF CANCER

IF6.8

2023-02-097

Roles of trans-lesion synthesis (TLS) DNA polymerases in tumorigenesis and cancer therapy

NAR CANCER

IF3.2

2023-02-0635

OAAI

Psymberin, a marine-derived natural product, induces cancer cell growth arrest and protein translation inhibition

FRONTIERS IN MEDICINE

IF3

2022-12-205

OAAI

Methotrexate recognition by the human reduced folate carrier SLC19A1

Nature

IF48.5

2022-09-070

PRE

Structure-Guided Synthesis of FK506 and FK520 Analogs with Increased Selectivity Exhibit In Vivo Therapeutic Efficacy against Cryptococcus

MBIO

IF4.7

2022-06-2813

OAAI

Novel Sulfonyl Piperzine Antibiotics Targeting the Lipid A Biosynthetic Enzyme LpxH in Gram-negative Bacteria

FASEB JOURNAL

IF4.2

2021-05-140

PRE

Synthesis and evaluation of cyclopentane-based muraymycin analogs targeting MraY

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-04-016

OAAI

Structure- and Ligand-Dynamics-Based Design of Novel Antibiotics Targeting Lipid A Enzymes LpxC and LpxH in Gram-Negative Bacteria

ACCOUNTS OF CHEMICAL RESEARCH

IF17.7

2021-03-1526

REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks

REV1抑制剂JH-RE-06通过触发衰老标志增强肿瘤细胞对化疗的反应

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-11-0934

OAAI

Evaluation of Manassantin A Tetrahydrofuran Core Region Analogues and Cooperative Therapeutic Effects with EGFR Inhibition

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-06-246

PREAI

Jiyong Hong

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