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VISTA checkpoint inhibition by pH-selective antibody SNS-101 with optimized safety and pharmacokinetic profiles enhances PD-1 response Thisted, Thomas; Smith, F. Donelson; Mukherjee, Arnab; Kleschenko, Yuliya; Feng, Feng; Jiang, Zhi-Gang; Eitas, Timothy; Malhotra, Kanam; Biesova, Zuzana; Onumajuru, Adejumoke; Finley, Faith; Cifuentes, Anokhi; Zhang, Guolin; Martin, Gaelle H.; Takeuchi, Yoshiko; Thiam, Kader; Schreiber, Robert D.; van der Horst, Edward H. 分享 收藏
Conditionally active CD28xVISTA bispecific antibodies induce myeloid-driven tumor-specific T-cell co-stimulation for improved cancer immunotherapy Thisted, Thomas; Jiang, Zhi-Gang; Biesova, Zuzana; Onumajuru, Adejumoke; Kleschenko, Yuliya; Malhotra, Kanam; Saxena, Vikas; Mukherjee, Arnab; Smith, F. Donelson; van der Horst, Edward H. 分享 收藏
Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma Lauer, Sophia M.; Omar, Mitchell H.; Golkowski, Martin G.; Kenerson, Heidi L.; Lee, Kyung-Soon; Pascual, Bryan C.; Lim, Huat C.; Forbush, Katherine; Smith, F. Donelson; Gordan, John D.; Ong, Shao-En; Yeung, Raymond S.; Scott, John D. 分享 收藏
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Mislocalization of protein kinase A drives pathology in Cushing?s syndrome 蛋白激酶A的错误定位驱动了库欣综合征的病理 Omar, Mitchell H.; Byrne, Dominic P.; Jones, Kiana N.; Lakey, Tyler M.; Collins, Kerrie B.; Lee, Kyung-Soon; Daly, Leonard A.; Forbush, Katherine A.; Lau, Ho-Tak; Golkowski, Martin; McKnight, G. Stanley; Breault, David T.; Lefrancois-Martinez, Anne-Marie; Martinez, Antoine; Eyers, Claire E.; Baird, Geoffrey S.; Ong, Shao-En; Smith, F. Donelson; Eyers, Patrick A.; Scott, John D. 分享 收藏
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A-kinase-anchoring protein 1 (dAKAP1)-based signaling complexes coordinate local protein synthesis at the mitochondrial surface 基于A激酶锚定蛋白1 (dAKAP1) 的信号复合物协调线粒体表面的局部蛋白质合成 Gabrovsek, Laura; Collins, Kerrie B.; Aggarwal, Stacey; Saunders, Lauren M.; Lau, Ho-Tak; Suh, Danny; Sancak, Yasemin; Trapnell, Cole; Ong, Shao-En; Smith, F. Donelson; Scott, John D. 分享 收藏
Subcellular Drug Targeting Illuminates Local Action of Polo-like kinase 1 and Aurora A During Mitosis Bucko, Paula; Lombard, Chloe; Rathbun, Lindsay; Bhat, Akansha; Garcia, Irvin; Wordeman, Linda; Smith, F.; Maly, Dustin; Hehnly, Heidi; Scott, John 分享 收藏
Hotspots of Aberrant Enhancer Activity in Fibrolamellar Carcinoma Reveal Candidate Oncogenic Pathways and Therapeutic Vulnerabilities Dinh, Timothy A.; Sritharan, Ramja; Smith, F. Donelson; Francisco, Adam B.; Ma, Rosanna K.; Bunaciu, Rodica P.; Kanke, Matt; Danko, Charles G.; Massa, Andrew P.; Scott, John D.; Sethupathy, Praveen 分享 收藏
Subcelluar drug targeting illuminates local kinase action Bucko, Paula J.; Lombard, Chloe K.; Rathbun, Lindsay; Garcia, Irvin; Bhat, Akansha; Wordeman, Linda; Smith, F. Donelson; Maly, Dustin J.; Hehnly, Heidi; Scott, John D. 分享 收藏
An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma Turnham, Rigney E.; Smith, F. Donelson; Kenerson, Heidi L.; Omar, Mitchell H.; Golkowski, Martin; Garcia, Irvin; Bauer, Renay; Lau, Ho-Tak; Sullivan, Kevin M.; Langeberg, Lorene K.; Ong, Shao-En; Riehle, Kimberly J.; Yeung, Raymond S.; Scott, John D. 分享 收藏
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Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins Smith, F. Donelson; Omar, Mitchell H.; Nygren, Patrick J.; Soughayer, Joseph; Hoshi, Naoto; Lau, Ho-Tak; Snyder, Calvin G.; Branon, Tess C.; Ghosh, Debapriya; Langeberg, Lorene K.; Ting, Alice Y.; Santana, Luis F.; Ong, Shao-En; Navedo, Manuel F.; Scott, John D. 分享 收藏
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PKA-Type I Selective Constrained Peptide Disruptors of AKAP Complexes Wang, Yuxiao; Ho, Tienhuei G.; Franz, Eugen; Hermann, Jennifer S.; Smith, F. Donelson; Hehnly, Heidi; Esseltine, Jessica L.; Hanold, Laura E.; Murph, Mandi M.; Bertinetti, Daniela; Scott, John D.; Herberg, Friedrich W.; Kennedy, Eileen J. 分享 收藏
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E2-Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis E2-Ub缀合物在发病过程中调节志贺氏菌效应OspG的激酶活性 Pruneda, Jonathan N.; Smith, F. Donelson; Daurie, Angela; Swaney, Danielle L.; Villen, Judit; Scott, John D.; Stadnyk, Andrew W.; Trong, Isolde Le; Stenkamp, Ronald E.; Klevit, Rachel E.; Rohde, John R.; Brzovic, Peter S. 分享 收藏