Stefan Gründer - Publications, H-index & Citations

Stefan Gründer

RWTH Aachen University

42H指数

168论文数

7.9K被引数

收录论文 63

发表时间

Thyroid hormones are positive allosteric modulators of acid-sensing ion channels ASIC1a and ASIC3 甲状腺激素是酸感应离子通道ASIC1a和ASIC3的正向别构调节剂

Neuropharmacology

IF4.6

2026-09-29

PREAI

Qin, Lu; Wiemuth, Dominik; Grunder, Stefan

The bile acid-sensive ion channel (BASIC) is expressed in pancreatic α-cells and involved in glucagon secretion 胆汁酸敏感离子通道（BASIC）在胰腺α细胞中表达并参与胰高血糖素分泌

Pflugers Archiv-European Journal of Physiology

IF2.9

2026-07-29

OAAI

Jingyu Yang; Stefan Gründer; Dominik Wiemuth

Functional Analysis of Ligand-Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling 刺胞动物中配体门控氯离子通道的功能分析为抑制性信号传导的演化提供了启示

Advanced Science

IF14.1

2026-05-01

OAAI

Abhilasha Ojha; Linda Kloss; Juan D. Montenegro; Simone Albani; Audrey Ortega-Ramírez; Mihaela Raycheva; Sylvia Joussen; Sabrina Kaul; Michèle Bachmann; Lisa Huf; Günther Schmalzing; Alison G. Cole; Ulrich Technau; Stefan Gründer

The secreted protein PCYOX1L controls the surface expression of acid-sensing ion channel 1a 分泌蛋白PCYOX1L调控酸敏感离子通道1a的表面表达

Science Advances

IF12.5

2025-07-25

OAAI

Sven Kuspiel; Maria Schilling; Felicitas Weiß; Alison Wiesehahn; Lea Strüver; Günther Schmalzing; Dominik Wiemuth; Stefan Gründer

A conserved peptide- binding pocket in HyNaC/ASIC ion channels

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-10-04

OAAI

Ortega-Ramirez, Audrey Magdalena; Albani, Simone; Bachmann, Michele; Schmidt, Axel; Pinoe, Manuela; Assmann, Marc; Augustinowski, Katrin; Rossetti, Giulia; Gruender, Stefan

Melatonin alters the excitability of mouse cerebellar granule neurons by inhibiting voltage-gated sodium, potassium, and calcium channels

JOURNAL OF PINEAL RESEARCH

IF6.3

2023-10-05

OAAI

Pissas, Karolos-Philippos; Schilling, Maria; Korkmaz, Ahmet; Tian, Yuemin; Gruender, Stefan

Physiologically relevant acid-sensing ion channel (ASIC) 2a/3 heteromers have a 1:2 stoichiometry

COMMUNICATIONS BIOLOGY

IF5.1

2023-07-08

OAAI

Fischer, Leon; Schmidt, Axel; Dopychai, Anke; Joussen, Sylvia; Joeres, Niko; Oslender-Bujotzek, Adrienne; Schmalzing, Guenther; Gruender, Stefan

Modulation of Acid-Sensing Ion Channels by Tannic Acid and Green Tea via a Membrane-Mediated Mechanism

ACS CHEMICAL NEUROSCIENCE

IF3.9

2023-06-28

PREAI

Hawashin, Ammar; Brakmann, Ilka C.; Tian, Yuemin; Gruender, Stefan; Ortega-Ramirez, Audrey M.

Functional analysis in a model sea anemone reveals phylogenetic complexity and a role in cnidocyte discharge of DEG/ENaC ion channels

COMMUNICATIONS BIOLOGY

IF5.1

2023-01-06

OAAI

Aguilar-Camacho, Jose Maria; Foreman, Katharina; Jaimes-Becerra, Adrian; Aharoni, Reuven; Gruender, Stefan; Moran, Yehu

Acidosis induces RIPK1-dependent death of glioblastoma stem cells via acid-sensing ion channel 1a

CELL DEATH & DISEASE

IF9.6

2022-08-12

OAAI

Clusmann, Jan; Franco, Klaus-Daniel Cortes; Suarez, David Alejandro Corredor; Katona, Istvan; Minguez, Maria Girbes; Boersch, Nina; Pissas, Karolos-Philippos; Vanek, Jakob; Tian, Yuemin; Gruender, Stefan

Personalized Medicine Approach in a DCM Patient with LMNA Mutation Reveals Dysregulation of mTOR Signaling

JOURNAL OF PERSONALIZED MEDICINE

IF3

2022-07-15

OAAI

Neupane, Balram; Pradhan, Kabita; Ortega-Ramirez, Audrey Magdalena; Aidery, Parwez; Kucikas, Vytautas; Marks, Matthias; van Zandvoort, Marc A. M. J.; Klingel, Karin; Witte, Klaus K.; Gruender, Stefan; Marx, Nikolaus; Gramlich, Michael

Dynorphin Neuropeptides Decrease Apparent Proton Affinity of ASIC1a by Occluding the Acidic Pocket

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-08-30

PREAI

Leisle, Lilia; Margreiter, Michael; Ortega-Ramirez, Audrey; Cleuvers, Elinor; Bachmann, Michele; Rossetti, Giulia; Gruender, Stefan

Large Acid-Evoked Currents, Mediated by ASIC1a, Accompany Differentiation in Human Dopaminergic Neurons

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2021-04-27

OAAI

Neuhof, Andreas; Tian, Yuemin; Reska, Anna; Falkenburger, Bjoern H.; Gruender, Stefan

Efficient expression of a cnidarian peptide-gated ion channel in mammalian cells

CHANNELS

IF3.2

2021-02-10

OAAI

Bachmann, Michele; Ortega-Ramirez, Audrey; Leisle, Lilia; Gruender, Stefan

Bile acids are potent inhibitors of rat P2X2receptors

PURINERGIC SIGNALLING

IF2.4

2019-05-17

OAAI

Schmidt, Axel; Joussen, Sylvia; Hausmann, Ralf; Gruender, Stefan; Wiemuth, Dominik

Screening of 109 neuropeptides on ASICs reveals no direct agonists and dynorphin A, YFMRFamide and endomorphin-1 as modulators

SCIENTIFIC REPORTS

IF3.9

2018-12-20

OAAI

Vyvers, Anna; Schmidt, Axel; Wiemuth, Dominik; Gruender, Stefan

The Conorfamide RPRFa Stabilizes the Open Conformation of Acid-Sensing Ion Channel 3 via the Nonproton Ligand-Sensing Domain

MOLECULAR PHARMACOLOGY

IF3

2018-10-01

OAAI

Reiners, Melissa; Margreiter, Michael A.; Oslender-Bujotzek, Adrienne; Rossetti, Giulia; Gruender, Stefan; Schmidt, Axel

Dual signaling of Wamide myoinhibitory peptides through a peptide-gated channel and a GPCR in Platynereis

FASEB JOURNAL

IF4.2

2018-04-24

OAAI

Schmidt, Axel; Bauknecht, Philipp; Williams, Elizabeth A.; Augustinowski, Katrin; Gruender, Stefan; Jekely, Gaspar

Modulation of DEG/ENaCs by Amphiphiles Suggests Sensitivity to Membrane Alterations

BIOPHYSICAL JOURNAL

IF3.1

2018-03-01

OAAI

Schmidt, Axel; Alsop, Rick J.; Rimal, Rahul; Lenzig, Pia; Joussen, Sylvia; Gervasi, Natalie N.; Khondker, Adree; Gruender, Stefan; Rheinstaedter, Maikel C.; Wiemuth, Dominik

The Mono-ADP-Ribosyltransferase ARTD10 Regulates KV1.1 through PKCD

BIOPHYSICAL JOURNAL

IF3.1

2018-02-01

OAAI

Tian, Yuemin; Verheugd, Patricia; Goswami, Priyanka; Goswami, Anand; Komnig, Daniel; Luescher, Bernhard; Gruender, Stefan

研究方向