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D

Dirk Jochmans

KU Leuven

44H指数
180论文数
8.1K被引数
收录论文 79
发表时间
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Design and anti-rhinovirus activity of novel derivatives based on the pleconaril core基于普乐沙福核心的新型衍生物的设计及其抗鼻病毒活性
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-07-01
err0
PREAI
errEgorova, Anna; Riabova, Olga; Kazakova, Elena; De Jonghe, Steven; Jochmans, Dirk; Neyts, Johan; Schmidtke, Michaela; Cogoni, Marta; Palmas, Vanessa; Khrenova, Maria; Sanna, Giuseppina; Makarov, Vadim
err分享
err收藏
Dual prodrugs of N4-hydroxycytidine with ProTide and ester modifications as anti-SARS-CoV-2 agentsN4-羟基胞苷的双前药，含ProTide和酯基修饰，作为抗SARS-CoV-2的药物
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-07-01
err0
PREAI
errLi, Ye; Zhang, Wenbo; Gao, Ni; Zhang, Chaoran; De Jonghe, Steven; Jochmans, Dirk; Neyts, Johan; Kang, Dongwei; Liu, Xinyong
err分享
err收藏
2-Phenylquinolines Exhibit Anti-Severe Acute Respiratory Syndrome Coronavirus-2 Activity Through the Nonstructural Protein 13 Helicase Inhibition2-苯基喹啉通过非结构蛋白13解旋酶抑制表现出抗严重急性呼吸综合征冠状病毒2活性
errChemMedChem
IF3.4
err2026-04-10
err0
errOAAI
errGiada Cernicchi; Maria Giulia Nizi; Roberta Emmolo; Leentje Persoons; Manon Laporte; Dirk Jochmans; Isabella Romeo; Giacomo Pepe; Ciro Milite; Pietro Campiglia; Jacopo Spezzini; Alma Martelli; Simone Brogi; Francesca Esposito; Tommaso Felicetti; Serena Massari; Giuseppe Manfroni; Stefano Sabatini; Gianluca Sbardella; Stefano Alcaro; Johan Neyts; Angela Corona; Enzo Tramontano; Steven De Jonghe; Oriana Tabarrini
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Thiazolyl 4-Carboxylate Ketone as a New Warhead for a Highly Potent SARS-CoV-2 Main Protease Inhibitor噻唑基4-羧酸酯酮作为高效SARS-CoV-2主蛋白酶抑制剂的新型战争头
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-11-29
err0
PREAI
errMaria A. Theodoropoulou; Haifa El Kilani; Christiana Mantzourani; Dirk Jochmans; Johan Neyts; Kaixuan Zhang; Judith Röske; Maroula G. Kokotou; Rolf Hilgenfeld; George Kokotos
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New 1,2,3-triazole-α-aminophosphonate acyclic nucleosides scaffold: Design, synthesis, docking studies and biological evaluation as potential S. aureus agents新型1,2,3-三唑-α-氨基磷酸盐无环核苷骨架：设计、合成、对接研究和作为潜在金黄色葡萄球菌（S. aureus）药物的生物评价
errJournal of Molecular Structure
IF4.7
err2025-10-27
err0
PREAI
errSaida Lachhab; Soukaina Elmoussaoui; Meriem Rafya; Az-eddine El Mansouri; Mohamed Maatallah; Ahmad Mehdi; Johan Neyts; Dirk Jochmans; Steven De Jonghe; Fatiha Benkhalti; Yogesh S. Sanghvi; Mustapha Ait Ali; Hassan B. Lazrek
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New spirooxindole-benzothiazole hybrids incorporating a trifluoromethyl moiety as antiviral agents: Design, synthesis, crystal structure analysis, and in silico studies新型含三氟甲基基团的螺恶唑烷酮-苯并噻唑杂化物作为抗病毒剂：设计、合成、晶体结构分析和计算机模拟研究
errJournal of Molecular Structure
IF4.7
err2025-09-20
err0
PREAI
errAsu Busra Temizer Keser; Görkem Güngör; Suzanne Kaptein; Dirk Jochmans; Mehmet Özbil; Filiz Betül Kaynak; Johan Neyts; Nilgün Karalı
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Antiviral activities of phenylalanine derivatives carrying carboxylic acid bioisosteres against chikungunya and parainfluenza virus type 3携带羧酸生物电子等排体的苯丙氨酸衍生物对基孔肯雅病毒和副流感病毒3型的抗病毒活性
errBioorganic & Medicinal Chemistry
IF3
err2025-08-11
err0
PREAI
errMerve Camcı Eren; Görkem Güngör; Steven De Jonghe; Dirk Jochmans; Mehmet Özbil; Johan Neyts; Suzanne Kaptein; Halil Şenol; Aytekin Köse; Mikail Hakan Gezginci; Nilgün Karalı
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Discovery and Preclinical Profile of ALG-097558; a Pan-Coronavirus 3CLpro InhibitorALG-097558的发现与临床前研究；一种广谱冠状病毒3CL蛋白酶抑制剂
errJournal of Medicinal Chemistry
IF6.8
err2025-06-30
err0
PREAI
errDorothée Bardiot; David C. McGowan; Kusum Gupta; Jerome Deval; Sandra Chang; Andreas Jekle; Cheng Liu; Sarah Stevens; Vladimir Serebryany; Marcel J. Tauchert; Klaus Maskos; Antitsa D. Stoycheva; Suping Ren; Ruchika Jaisinghani; Marine O. Faucher; Tse-I Lin; Sandro Boland; Patrick Chaltin; Arnaud Marchand; Jurgen Wuyts; Steven De Jonghe; Dirk Jochmans; Sreenivasa Anugu; Vamshi Baloju; Kiran Deta; Michael Welch; Pieter Leyssen; Johan Neyts; Manon Laporte; Rana Abdelnabi; Haiyang Hu; Peng Zhang; Kha Le; Sushmita Chanda; David B. Smith; Pierre Raboisson; Leonid Beigelman; Julian A. Symons; Lawrence Blatt; Koen Vandyck
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The Combination of GS-441524 (Remdesivir) and Ribavirin Results in a Potent Antiviral Effect Against Human Parainfluenza Virus 3 Infection in Human Airway Epithelial Cell Cultures and in a Mouse Infection Model
errVIRUSES-BASEL
IF3.5
err2025-01-26
err0
errOAAI
errLin, Yuxia; Weynand, Birgit; Zhang, Xin; Laporte, Manon; Jochmans, Dirk; Neyts, Johan
err分享
err收藏
Structure-Based Optimization of Pyridone α-Ketoamides as Inhibitors of the SARS-CoV-2 Main Protease基于结构的吡啶酮α-酮酰胺类作为SARS-CoV-2主蛋白酶抑制剂的优化
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-01-16
err1
errOAAI
errAkula, Ravi Kumar; El Kilani, Haifa; Metzen, Alina; Roeske, Judith; Zhang, Kaixuan; Goehl, Matthias; Arisetti, Nanaji; Marsh, Graham P.; Maple, Hannah J.; Cooper, Mark S.; Karadogan, Burhan; Jochmans, Dirk; Neyts, Johan; Rox, Katharina; Hilgenfeld, Rolf
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Protecting Group Control of Hydroxyketone-Hemiketal Tautomeric Equilibrium Enables the Stereoselective Synthesis of a 1′-Azido C-Nucleoside
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2024-11-19
err0
PREAI
errPanda, Subhankar; Orimoloye, Moyosore O.; Poudel, Tej Narayan; De Jonghe, Steven; Jochmans, Dirk; Neyts, Johan; Aldrich, Courtney C.
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A robust mouse model of HPIV-3 infection and efficacy of GS-441524 against virus-induced lung pathology
errNATURE COMMUNICATIONS
IF15.7
err2024-09-05
err0
errOAAI
errLin, Yuxia; Khan, Mona; Weynand, Birgit; Laporte, Manon; Coenjaerts, Frank; Babusis, Darius; Bilello, John P.; Mombaerts, Peter; Jochmans, Dirk; Neyts, Johan
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New Schiff bases and their vanadium complexes: Synthesis, characterization, and biological assessment for antibacterial and antiviral action
errAPPLIED ORGANOMETALLIC CHEMISTRY
IF0
err2024-05-24
err3
PREAI
errKhaldoune, Khadija; Hasnaoui, Ali; Rafya, Meryem; Es-sakhi, Meriem; Benkhalti, Fatiha; Hdoufane, Ismail; Mague, Joel T.; Neyts, Johan; Jochmans, Dirk; Cherqaoui, Driss; el Firdoussi, Larbi; Fdil, Naima; Lazrek, Hassan Bihi; Ait Ali, Mustapha
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Proof of stability of an RSV Controlled Human Infection Model challenge agent
errVIROLOGY JOURNAL
IF3.8
err2024-05-15
err1
errOAAI
errVerstraelen, Sandra; Roymans, Dirk; Jacobs, An; Hollanders, Karen; Remy, Sylvie; Jochmans, Dirk; Klein, Jelle; Grauwet, Tini
err分享
err收藏
Design, synthesis, and molecular modeling studies of novel 2-quinolone-1,2,3-triazole-α-aminophosphonates hybrids as dual antiviral and antibacterial agents
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-03-01
err13
PREAI
errEl Gadali, Khadija; Rafya, Meriem; El Mansouri, Az-eddine; Maatallah, Mohamed; Vanderlee, Arie; Mehdi, Ahmad; Neyts, Johan; Jochmans, Dirk; De Jonghe, Steven; Benkhalti, Fatiha; Sanghvi, Yogesh S.; Taourirte, Moha; Lazrek, Hassan B.
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err收藏
Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warranted
errEBIOMEDICINE
IF10.8
err2024-02-01
err2
errOAAI
errAcar, Delphine Diana; Witkowski, Wojciech; Wejda, Magdalena; Wei, Ruifang; Desmet, Tim; Schepens, Bert; De Cae, Sieglinde; Sedeyn, Koen; Eeckhaut, Hannah; Fijalkowska, Daria; Roose, Kenny; Vanmarcke, Sandrine; Poupon, Anne; Jochmans, Dirk; Zhang, Xin; Abdelnabi, Rana; Foo, Caroline S.; Weynand, Birgit; Reiter, Dirk; Callewaert, Nico; Remaut, Han; Neyts, Johan; Saelens, Xavier; Gerlo, Sarah; Vandekerckhove, Linos
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A Robust Phenotypic High-Throughput Antiviral Assay for the Discovery of Rabies Virus Inhibitors
errVIRUSES-BASEL
IF3.5
err2023-11-23
err0
errOAAI
errWang, Xinyu; Chiu, Winston; Klaassen, Hugo; Marchand, Arnaud; Chaltin, Patrick; Neyts, Johan; Jochmans, Dirk
err分享
err收藏
Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters
errJOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
IF3.6
err2023-11-23
err3
errOAAI
errBox, Helen J.; Sharp, Joanne; Pennington, Shaun H.; Kijak, Edyta; Tatham, Lee; Caygill, Claire H.; Lopeman, Rose C.; Jeffreys, Laura N.; Herriott, Joanne; Neary, Megan; Valentijn, Anthony; Pertinez, Henry; Curley, Paul; Arshad, Usman; Rajoli, Rajith K. R.; Jochmans, Dirk; Vangeel, Laura; Neyts, Johan; Chatelain, Eric; Escudie, Fanny; Scandale, Ivan; Rannard, Steve; Stewart, James P.; Biagini, Giancarlo A.; Owen, Andrew
err分享
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Intranasal administration of convalescent plasma protects against SARS-CoV-2 infection in hamsters
errEBIOMEDICINE
IF10.8
err2023-06-01
err4
errOAAI
errWouters, Elise; Verbrugghe, Caro; Abdelnabi, Rana; Devloo, Rosalie; De Clippel, Dorien; Jochmans, Dirk; De Bleser, Dominique; Weynand, Birgit; Compernolle, Veerle; Neyts, Johan; Feys, Hendrik B.
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Urtica dioica Agglutinin Prevents Rabies Virus Infection in a Muscle Explant Model荨麻凝集素在肌肉外植体模型中预防狂犬病病毒感染
errPHARMACEUTICS
IF5.5
err2023-04-28
err4
errOAAI
errWang, Xinyu; Terrie, Lisanne; Wu, Guanghui; Van Damme, Els J. M.; Thorrez, Lieven; Fooks, Anthony R.; Banyard, Ashley C.; Jochmans, Dirk; Neyts, Johan
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