Jianhua Gan - Publications, H-index & Citations

Jianhua Gan

fudan university

39H指数

252论文数

6.9K被引数

收录论文 92

发表时间

A complement C5-targeted GalNAc-conjugated siRNA with sustained efficacy in a non-human primate model of IgA nephropathy 靶向补体C5的GalNAc偶联siRNA在非人灵长类IgA肾病模型中具有持续疗效

Molecular Therapy

IF12

2026-08-13

OAAI

Xueyan Zhang; Xue Zhang; Qiuyu Yang; Bin Kang; Mo Dan; Chunlei Li; Yan Chen; Jianhua Gan; Xiaoye Su

H3K4me1 directs H3K36me2 and H3K36me3 deposition in land plants H3K4me1指导陆地植物中的H3K36me2和H3K36me3沉积

Nature Communications

IF15.7

2026-02-16

OAAI

Jiabing Wu; Jiachen Wang; Kangxi Du; Yingping Li; Wenhao Xie; Chenxi He; Qidan Xing; Xiang Li; Xiaoyu Zhu; Zhen Wu; Xiaolong Wu; Linghao Zhang; Wen-Hui Shen; Fei Lan; Jianhua Gan; Bing Liu; Aiwu Dong

Targeting transthyretin by one Cas9 variant with superfidelity and broad compatibility

SCIENCE ADVANCES

IF12.5

2026-01-02

PREAI

Qi, Sixian; Wei, Lifan; Ding, Zhan; Zhong, Feiya; Yang, Sicong; Wu, Leibin; Yang, Xuan; Kang, Bin; Dan, Mo; Gan, Jianhua; Li, Chunlei; Su, Xiaoye

Author Correction: Cryo-EM structure of a natural RNA nanocage 作者更正: 天然RNA纳米卡的cryo-em结构

Nature

IF48.5

2025-12-19

PREAI

Xiaobin Ling; Dmitrij Golovenko; Jianhua Gan; Jinbiao Ma; Andrei A. Korostelev; Wenwen Fang

Crystal structures and snapshots along Tpt1-catalyzed phosphate transfer from nucleic acid to NAD+Tpt1催化的核酸到NAD+磷酸转移过程中的晶体结构和快照

Nature Communications

IF15.7

2025-12-04

OAAI

Chulei Cao; Jie Yang; Weizhen Zhang; Jiaqin Chen; Yanqing Gao; Yuqi Yao; Yixi Zhang; Huili Li; Linxi Li; Zhaorong Luo; Chenxi Wang; Guangli Tang; Ruixue Cui; Hehua Liu; Qiyao Wang; Zhen Huang; Jinbiao Ma; Jianhua Gan

Assembly and inhibition of transferable TMexCD1-TOprJ1 efflux pump 转移性TMexCD1-TOprJ1外排泵的组装与抑制

Nature Communications

IF15.7

2025-11-14

OAAI

Yu Shi; Mengyuan Li; Tao Cui; Jianhua Gan; Haomin Huang; Zhi Su; Runshi Yang; Xing Zhang; Huimin Zhang; Yu Feng; Youjun Feng

Catalytic-state structure of Candidatus Hydrogenedentes Cas12b revealed by cryo-EM studies 通过冷冻电镜研究揭示的Candidatus Hydrogenedentes Cas12b的催化态结构

NUCLEIC ACIDS RESEARCH

IF13.1

2025-07-08

OAAI

Li, Ye; Li, Jian; Pei, Xiaotong; Wei, Jingjing; Gan, Jianhua; Lin, Jinzhong

Development of Orally Bioavailable FTO Inhibitors with Potent Antileukemia Efficacy 开发具有强效抗白血病活性的口服生物利用度FTO抑制剂

Journal of Medicinal Chemistry

IF6.8

2025-06-28

PREAI

Teng Yang; Ze Dong; Rong Du; Yiqing Wang; Lu Liu; Yangyang Xue; Xi Zhang; Yonggang Liao; Jianhua Gan; Xiaoxuan Yu; Yue Huang; Cai-Guang Yang

Megavirus baoshanense Mb0671 modulates host translation and increases viral fitness Megavirus baoshanense Mb0671调节宿主翻译并增加病毒适应性

FRONTIERS IN MICROBIOLOGY

IF4.5

2025-04-28

OAAI

Bian, Wenya; Yang, Jie; Xia, Yucheng; Li, Yun; Cheng, Yanjin; Wu, Yuchen; Gan, Jianhua; Zhong, Jiang

Structure-Based Development of a Covalent Inhibitor Targeting Streptococcus Pyogenes over Staphylococcus Aureus Sortase A

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2025-03-01

PREAI

Zhou, Hailing; Yuan, Ziqi; Guan, Xiang-Na; Yue, Chuan; Wu, Wei; Lan, Lefu; Gan, Jianhua; Zhang, Tao; Yang, Cai-Guang

A bacterial methyltransferase that initiates biotin synthesis, an attractive anti-ESKAPE druggable pathway 一种启动生物素合成的细菌甲基转移酶，一种有吸引力的抗ESKAPE药物途径

SCIENCE ADVANCES

IF12.5

2024-12-20

OAAI

Su, Zhi; Zhang, Weizhen; Shi, Yu; Cui, Tao; Xu, Yongchang; Yang, Runshi; Huang, Man; Zhou, Chun; Zhang, Huimin; Lu, Ting; Qu, Jiuxin; He, Zheng-Guo; Gan, Jianhua; Feng, Youjun

Cofactor binding triggers rapid conformational remodelling of the active site of a methyltransferase ribozyme

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-11-01

PREAI

Jiang, Hengyi; Liu, Getong; Gao, Yanqing; Gan, Jianhua; Chen, Dongrong; Murchie, Alastair I. H.

Structural insights into the biosynthetic mechanism of Nα-GlyT and 5-NmdU hypermodifications of DNA

NUCLEIC ACIDS RESEARCH

IF13.1

2024-09-12

OAAI

Wen, Yan; Guo, Wenting; Meng, Chunyan; Yang, Jie; Xu, Sha; Chen, Haitao; Gan, Jianhua; Wu, Baixing

Structures of African swine fever virus topoisomerase complex and their implications

NATURE COMMUNICATIONS

IF15.7

2024-08-01

OAAI

Yang, Jie; Shao, Zhiwei; Zhao, Xin; Zhang, Weizhen; Zhang, Yixi; Li, Linxi; Gao, Yanqing; Shao, Qiyuan; Cao, Chulei; Li, Huili; Cui, Ruixue; Liu, Hehua; Gan, Jianhua

Structural and functional insights into the helicase protein E5 of Mpox virus

CELL DISCOVERY

IF12.5

2024-06-25

OAAI

Zhang, Weizhen; Liu, Yusong; Yang, Mengquan; Yang, Jie; Shao, Zhiwei; Gao, Yanqing; Jiang, Xinran; Cui, Ruixue; Zhang, Yixi; Zhao, Xin; Shao, Qiyuan; Cao, Chulei; Li, Huili; Li, Linxi; Liu, Hehua; Gao, Haishan; Gan, Jianhua

Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma

NATURE COMMUNICATIONS

IF15.7

2023-11-03

OAAI

Zhou, Lin-Lin; Zhang, Tao; Xue, Yun; Yue, Chuan; Pan, Yihui; Wang, Pengyu; Yang, Teng; Li, Meixia; Zhou, Hu; Ding, Kan; Gan, Jianhua; Ji, Hongbin; Yang, Cai-Guang

Shade-induced RTFL/DVL peptides negatively regulate the shade response by directly interacting with BSKs in Arabidopsis

NATURE COMMUNICATIONS

IF15.7

2023-10-28

OAAI

Huang, Sha; Ma, Yu; Xu, Yitian; Lu, Pengfei; Yang, Jie; Xie, Yu; Gan, Jianhua; Li, Lin

Assessment of the structure-activity relationship and antileukemic activity of diacylpyramide compounds as human ClpP agonists 评估作为人ClpP激动剂的二酰基吡酰胺化合物的构效关系和抗白血病活性

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2023-10-01

PREAI

Zhang, Ranran; Wang, Pengyu; Wei, Bingyan; Chen, Liang; Song, Xiaomin; Pan, Yihui; Li, Jiahui; Gan, Jianhua; Zhang, Tao; Yang, Cai-Guang

Molecular basis and engineering of miniature Cas12f with C-rich PAM specificity

NATURE CHEMICAL BIOLOGY

IF13.7

2023-09-11

PREAI

Su, Mengjiao; Li, Fan; Wang, Yujue; Gao, Yan; Lan, Weiqi; Shao, Zhiwei; Zhu, Chen; Tang, Na; Gan, Jianhua; Wu, Zhaowei; Ji, Quanjiang

Structural and functional studies of PCNA from African swine fever virus

JOURNAL OF VIROLOGY

IF3.8

2023-08-31

OAAI

Shao, Zhiwei; Yang, Jie; Gao, Yanqing; Zhang, Yixi; Zhao, Xin; Shao, Qiyuan; Zhang, Weizhen; Cao, Chulei; Liu, Hehua; Gan, Jianhua

研究方向