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A

Andreas Plückthun

university of zurich

112H指数
724论文数
4.2W被引数
收录论文 233
发表时间
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Docking of virtual libraries identifies small-molecule agonists of neurotensin receptors with analgesic activity虚拟库的对接鉴定出具有镇痛活性的神经tensin受体小分子激动剂
errNature Communications
IF15.7
err2026-07-22
err0
errOAAI
errNicolas Panel; Duy Duc Vo; Harald Hübner; Mattia Deluigi; Szymon Pach; Félix Bélair; Dorothee Weikert; Christoph Klenk; Mark Hilge; Niharika Shiva; Isabelle Brochu; Jean-Michel Longpré; Frida Bällgren; Aljona Saleh; Huabin Hu; Jon Kapla; Stefanie Kampen; Israel Cabeza de Vaca; Jan Kihlberg; Nina Wettschureck; Philippe Sarret; Andreas Plückthun; Peter Gmeiner; Jens Carlsson
err分享
err收藏
Transcriptional transactivation turns human iPSC-derived macrophages into an adenovirus-producing cell state转录激活将人iPSC来源的巨噬细胞转变为腺病毒产生细胞状态
errJournal of Virology
IF3.8
err2026-06-23
err0
PREAI
errSuomalainen, Maarit; Haenseler, Walther; Kolibius, Jonas; Pluckthun, Andreas; Hearing, Patrick; Greber, Urs F.
err分享
err收藏
Cryo-EM structures of higher order Gephyrin oligomers reveal principles of inhibitory postsynaptic scaffold organization冷冻电镜揭示高阶Gephyrin寡聚物的结构及抑制性突触后支架组织的原理
errNature Communications
IF15.7
err2026-04-16
err0
errOAAI
errDiego Ortiz-López; Tamsanqa T. Hove; Christiane Huhn; Serena Camuso; Pia M. van gen Hassend; Bodo Sander; Benjamin F. N. Campbell; Shiva K. Tyagarajan; Andreas Plückthun; Christian G. Specht; Hans M. Maric; Bettina Böttcher; Hermann Schindelin
err分享
err收藏
Pre-assembly of biomolecular condensate seeds drives RSV replication生物分子缩合物种子的预组装驱动RSV复制
errNature
IF48.5
err2026-01-28
err0
errOAAI
errDhanushika Ratnayake; Marie Galloux; Sanne Boersma; Marko Noerenberg; Christina Sizun; Carlos Sacristan; Julien Sourimant; Anke J. Lakerveld; Anne T. Gelderloos; Leonie Apperloo; Yana Demyanenko; Matthijs J. D. Baars; Rupa Banerjee; Birgit Dreier; Sven Furler; Natalie I. Mazur; Louis J. Bont; Shabaz Mohammed; Andreas Plückthun; Jean-François Éléouët; Geert J. P. L. Kops; Alfredo Castello; Puck B. van Kasteren; Marie-Anne Rameix-Welti; Marvin E. Tanenbaum
err分享
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Quantitative Degradation Rate Assessment of bioPROTACs Based on Peptide Degrons, E3 Domains, Adapters and Conjugated Small Molecules
errACS CHEMICAL BIOLOGY
IF3.8
err2026-01-01
err0
PREAI
errVukovic, David; Winkelvoss, Dorothea; Udovcic, Anto; Riermeier, Luca; Jaime-Figueroa, Saul; Crews, Craig M.; Pluckthun, Andreas
err分享
err收藏
Genome-replicating HC-AdV – a novel high-capacity adenoviral vector class featuring enhanced in situ payload expression基因组复制型HC-AdV——一种具有增强原位载荷表达的新型高容量腺病毒载体类别
errMolecular Therapy Methods & Clinical Development
IF4.7
err2025-09-01
err0
errOAAI
errJonas Kolibius; Fabian Weiss; Patrick C. Freitag; Andreas Plückthun
err分享
err收藏
Structural analysis of HER2-trastuzumab complex reveals receptor conformational adaptationHER2-曲妥珠单抗复合物的结构分析揭示了受体构象适应性
errScience Advances
IF12.5
err2025-07-25
err0
errOAAI
errSantiago Vacca; Marcos Gragera; Alejandro Buschiazzo; David Herreros; James M. Krieger; Santiago Bonn-Garcia; Roberto Melero; Carlos OS. Sorzano; Jose M. Carazo; Ohad Medalia; Andreas Plückthun
err分享
err收藏
A nucleotide-independent, pan-RAS-targeted DARPin elicits anti-tumor activity in a multimodal manner一种不依赖核苷酸、泛RAS靶向的DARPin以多模式方式诱导抗肿瘤活性
errMolecular Oncology
IF4.5
err2025-06-15
err0
errOAAI
errJonas N. Kapp; Wouter P. R. Verdurmen; Jonas V. Schaefer; Kari Kopra; Gabriela Nagy-Davidescu; Elodie Richard; Marie-Julie Nokin; Patrick Ernst; Rastislav Tamaskovic; Martin Schwill; Ralph Degen; Claudia Scholl; David Santamaria; Andreas Plückthun
err分享
err收藏
Activated blood-derived human primary T cells support replication of HAdV C5 and virus transmission to polarized human primary epithelial cells活化的外周血来源的人原代T细胞支持HAdV C5的复制及向极化的人原代上皮细胞的病毒传播
errJOURNAL OF VIROLOGY
IF3.8
err2025-05-20
err0
errOAAI
errSequeira, Daniela Policarpo; Suomalainen, Maarit; Freitag, Patrick C.; Pluckthun, Andreas; Fischer, Lucy; Hemmi, Silvio; Munz, Christian; Volle, Romain
err分享
err收藏
DARPins as a novel tool to detect and degrade p73
errCELL DEATH & DISEASE
IF9.6
err2024-12-18
err0
errOAAI
errMuenick, Philipp; Zielinski, Jasmin; Strubel, Alexander; Gutfreund, Niklas; Dreier, Birgit; Schaefer, Jonas V.; Schaefer, Birgit; Gebel, Jakob; Osterburg, Christian; Chaikuad, Apirat; Knapp, Stefan; Plueckthun, Andreas; Doetsch, Volker
err分享
err收藏
Protein degradation kinetics measured by microinjection and live-cell fluorescence microscopy
errSCIENTIFIC REPORTS
IF3.9
err2024-11-07
err0
errOAAI
errVukovic, David; Winkelvoss, Dorothea; Kapp, Jonas N.; Hanny, Anna-Carina; Burgisser, Heloise; Riermeier, Luca; Udovcic, Anto; Tiefenboeck, Peter; Pluckthun, Andreas
err分享
err收藏
Experimental variables determine the outcome of RAS-RAS interactions实验变量决定了RAS-RAS相互作用的结果
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-11-01
err0
PREAI
errZhou, Zhiwei; Nguyen, Tra Ly; Li, Xingxiao; Poujol, Christel; Berlinska, Ewa; Michelina, Sandra Vietti; Kapp, Jonas N.; Plueckthun, Andreas; Winslow, Monte M.; Ambrogio, Chiara; Shan, Yibing; Santamaria, David; Westover, Kenneth D.
err分享
err收藏
Beyond KRAS(G12C): Biochemical and Computational Characterization of Sotorasib and Adagrasib Binding Specificity and the Critical Role of H95 and Y96超越KRAS(G12C): Sotorasib和Adagrasib结合特异性的生化和计算表征以及H95和Y96的关键作用
errACS CHEMICAL BIOLOGY
IF3.8
err2024-09-16
err1
PREAI
errMahran, Randa; Kapp, Jonas N.; Valtonen, Salla; Champagne, Allison; Ning, Jinying; Gillette, William; Stephen, Andrew G.; Hao, Feng; Pluckthun, Andreas; Harma, Harri; Pantsar, Tatu; Kopra, Kari
err分享
err收藏
A designed ankyrin-repeat protein that targets Parkinson's disease-associated LRRK2一种针对帕金森病相关LRRK2的锚蛋白重复蛋白
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-07-01
err0
errOAAI
errDederer, Verena; Murillo, Marta Sanz; Karasmanis, Eva P.; Hatch, Kathryn S.; Chatterjee, Deep; Preuss, Franziska; Azeez, Kamal R. Abdul; Nguyen, Landon Vu; Galicia, Christian; Dreier, Birgit; Plueckthun, Andreas; Versees, Wim; Mathea, Sebastian; Leschziner, Andres E.; Reck-Peterson, Samara L.; Knapp, Stefan
err分享
err收藏
Modular binder technology by NGS- aided, high- resolution selection in yeast of designed armadillo modules
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-06-25
err0
errOAAI
errStark, Yvonne; Menard, Faye; Jeliazkov, Jeliazko R.; Ernst, Patrick; Chembath, Anupama; Ashraf, Mohammed; Hine, Anna V.; Pluckthun, Andreas
err分享
err收藏
Broadening the Utility of Farnesyltransferase-Catalyzed Protein Labeling Using Norbornene-Tetrazine Click Chemistry
errBIOCONJUGATE CHEMISTRY
IF3.9
err2024-04-24
err1
PREAI
errAuger, Shelby A.; Venkatachalapathy, Sneha; Suazo, Kiall Francis G.; Wang, Yiao; Sarkis, Alexander W.; Bernhagen, Kaitlyn; Justyna, Katarzyna; Schaefer, Jonas V.; Wollack, James W.; Plu''ckthun, Andreas; Li, Ling; Distefano, Mark D.
err分享
err收藏
Designed Ankyrin Repeat Proteins as Actin Labels of Distinct Cytoskeletal Structures in Living Cells设计的锚蛋白重复蛋白作为活细胞中不同细胞骨架结构的肌动蛋白标记
errACS NANO
IF16
err2024-03-15
err4
errOAAI
errIvanova, Julia R.; Benk, Amelie S.; Schaefer, Jonas V.; Dreier, Birgit; Hermann, Leon O.; Pluckthun, Andreas; Missirlis, Dimitris; Spatz, Joachim P.
err分享
err收藏
Identification of a Novel Subtype-Selective α1B-Adrenoceptor Antagonist
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2024-01-18
err0
errOAAI
errAbdul-Ridha, Alaa; de Zhang, Lazarus A.; Betrie, Ashenafi Haileyesus; Deluigi, Mattia; Vaid, Tasneem M.; Whitehead, Alice; Zhang, Yifan; Davis, Ben; Harris, Richard; Simmonite, Heather; Hubbard, Roderick E.; Gooley, Paul R.; Plu''ckthun, Andreas; Bathgate, Ross A. D.; Chalmers, David K.; Scott, Daniel J.
err分享
err收藏
A DARPin promotes faster onset of botulinum neurotoxin A1 action
errNATURE COMMUNICATIONS
IF15.7
err2023-12-18
err0
errOAAI
errLeka, Oneda; Wu, Yufan; Zanetti, Giulia; Furler, Sven; Reinberg, Thomas; Marinho, Joana; Schaefer, Jonas V.; Pluckthun, Andreas; Li, Xiaodan; Pirazzini, Marco; Kammerer, Richard A.
err分享
err收藏
Unexpected dynamics in femtomolar complexes of binding proteins with peptides
errNATURE COMMUNICATIONS
IF15.7
err2023-11-28
err1
errOAAI
errCucuzza, Stefano; Sitnik, Malgorzata; Jurt, Simon; Michel, Erich; Dai, Wenzhao; Muntener, Thomas; Ernst, Patrick; Haussinger, Daniel; Pluckthun, Andreas; Zerbe, Oliver
err分享
err收藏

研究方向

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合作学者
合作期刊
D
Dennis R. Burton
H 指数: 172 · 论文数: 800
A
Albert J. R. Heck
H 指数: 132 · 论文数: 1.2K
R
Rolf M. Zinkernagel
H 指数: 127 · 论文数: 620
P
Peter D. Kwong
H 指数: 122 · 论文数: 734
O
Olli Kallioniemi
H 指数: 122 · 论文数: 954
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