Adrian B. McDermott - Publications, H-index & Citations

Adrian B. McDermott

UMass Chan Medical School

77H指数

299论文数

2.6W被引数

收录论文 157

发表时间

VRC01 with antiretroviral initiation in infants is well tolerated; and higher concentrations associate with greater HIV-1 DNA declines 婴儿期抗逆转录病毒启动的VRC01耐受性良好；较高浓度与更大的HIV-1 DNA下降相关

Science Translational Medicine

IF14.6

2026-05-06

PREAI

Alka Khaitan; Jane C. Lindsey; Edmund V. Capparelli; Camlin Tierney; Anne Coletti; Charlotte Perlowski; Dwight E. Yin; Mary Elizabeth (Betsy) Smith; Hans M. L. Spiegel; Sai Majji; Jack Moye; Lucio Gama; Richard A. Koup; Bob C. Lin; Adrian B. McDermott; Lynette Purdue; Chelsea Krotje; Paul A. Harding; Mark F. Cotton; Diane Costello; Christos J. Petropoulos; Jacqueline D. Reeves; Macpherson Mallewa; Rachel Chihana; Portia Kamthunzi; Tapiwa G. Mbengeranwa; Gaerolwe Masheto; Maria Letícia Santos Cruz; Jose Henrique Pilotto; Ponego L. Ponatshego; Deborah Persaud; Elizabeth J. McFarland;

Prospective SARS-CoV-2 additional vaccination in immunosuppressanttreated individuals with autoimmune diseases in a randomized controlled trial 在随机对照试验中，免疫抑制治疗的自身免疫性疾病患者中SARS-CoV-2加强疫苗接种的前瞻性研究

JCI Insight

IF6.1

2026-01-09

OAAI

Mackay, Meggan; Wagner, Catriona A.; Pinckney, Ashley; Cohen, Jeffrey A.; Wallace, Zachary S.; Khosroshahi, Arezou; Sparks, Jeffrey A.; Lord, Sandra; Saxena, Amit; Caricchio, Roberto; Kim, Alfred H. J.; Kamen, Diane L.; Koumpouras, Fotios; Askanase, Anca D.; Smith, Kenneth; Guthridge, Joel M.; Pardo, Gabriel; Mao-Draayer, Yang; Macwana, Susan; McCarthy, Sean; Sherman, Matthew A.; Hamrah, Sanaz Daneshfar; Veri, Maria; Walker, Sarah; York, Kate; Tedeschi, Sara K.; Wang, Jennifer; Dziubla, Gabrielle; Castro, Mike; Carroll, Robin; Narpala, Sandeep; Lin, Bob C.; Serebryannyy, Leonid; McDermott, Adrian B.; Barry, William T.; Goldmuntz, Ellen; McNamara, James; Payne, Aimee S.; Bar-Or, Amit; Khanna, Dinesh; James, Judith A.

Immune correlates analysis of antibody responses against SARS-CoV-2 variants in the ENSEMBLE vaccine efficacy trial SARS-CoV-2变异株抗体反应的免疫相关性分析：ENSEMBLE疫苗有效性试验

iScience

IF4.1

2025-09-29

OAAI

Alex Luedtke; Youyi Fong; Lars van der Laan; Fei Heng; Ying Huang; Yiwen Lu; Chenchen Yu; Lindsay N. Carpp; Sanne Roels; Mathieu Le Gars; Griet A. Van Roey; Daniel J. Stieh; Ilse Van Dromme; Avi Kenny; Marco Carone; Ollivier Hyrien; Victor Ayala; Lakshmi Jayashankar; Flora Castellino; Obrimpong Amoa-Awua; Manjula Basappa; Britta Flach; Bob C. Lin; Christopher Moore; Mursal Naisan; Muhammed Naqvi; Sandeep Narpala; Sarah O’Connell; Allen Mueller; Leo Serebryannyy; Mike Castro; Jennifer Wang; Gabrielle Dziubla; April K. Randhawa; Michele P. Andrasik; Jenny Hendriks; Carla Truyers; Frank Struyf; Hanneke Schuitemaker; Macaya Douoguih; James G. Kublin; Lawrence Corey; Kathleen M. Neuzil; Linda-Gail Bekker; Nigel Garrett; Sandra W. Cardoso; Patrice DelaFontaine; Craig A. Magaret; Johan Vingerhoets; Martin Casapia; Marcelo H. Losso; Susan J. Little; Aditya Gaur; Edith Swann; Christos J. Petropoulos; Adrian B. McDermott; Jerald Sadoff; Glenda E. Gray; Beatriz Grinsztejn; Paul A. Goepfert; Dean Follmann; Pavitra Roychoudhury; Alexander L. Greninger; Richard A. Koup; Ruben O. Donis; Peter B. Gilbert

The N terminus of H3-influenza hemagglutinin as a site-of-vulnerability to neutralizing antibody H3型流感血凝素N端作为中和抗体的易感位点

Structure

IF4.3

2025-08-14

OAAI

Reda Rawi; Nicholas C. Morano; Crystal Sao-Fong Cheung; Haijuan Du; Jason Gorman; Madhu Prabhakaran; Jordan E. Becker; Tatsiana Bylund; Sam Charaf; Xuejun Chen; Myungjin Lee; Darcy R. Harris; Adam S. Olia; Li Ou; Lingshu Wang; Shuishu Wang; Baoshan Zhang; Masaru Kanekiyo; Adrian B. McDermott; Tongqing Zhou; Lawrence Shapiro; Peter D. Kwong

Structural convergence and water-mediated substrate mimicry enable broad neuraminidase inhibition by human antibodies 结构趋同和水介导的底物模拟使人类抗体能够广泛抑制神经氨酸酶

Nature Communications

IF15.7

2025-08-01

OAAI

Julia Lederhofer; Andrew J. Borst; Lam Nguyen; Rebecca A. Gillespie; Connor J. Williams; Emma L. Walker; Julie E. Raab; Christina Yap; Daniel Ellis; Adrian Creanga; Hyon-Xhi Tan; Thi H. T. Do; Michelle Ravichandran; Adrian B. McDermott; Valerie Le Sage; Sarah F. Andrews; Barney S. Graham; Adam K. Wheatley; Douglas S. Reed; Neil P. King; Masaru Kanekiyo

Precise targeting of HIV broadly neutralizing antibody precursors in humans 精确靶向人类HIV广谱中和抗体前体

Science

IF45.8

2025-05-15

PREAI

Tom G. Caniels; Madhu Prabhakaran; Gabriel Ozorowski; Kellie J. MacPhee; Weiwei Wu; Karlijn van der Straten; Sashank Agrawal; Ronald Derking; Emma I. M. M. Reiss; Katrina Millard; Martina Turroja; Aimee Desrosiers; Jeffrey Bethony; Elissa Malkin; Marinus H. Liesdek; Annelou van der Veen; Michelle Klouwens; Jonne L. Snitselaar; Joey H. Bouhuijs; Rhianna Bronson; Jalen Jean-Baptiste; Suprabhath Gajjala; Zahra Rikhtegaran Tehrani; Alison Benner; Mukundhan Ramaswami; Michael O. Duff; Yung-Wen Liu; Alicia H. Sato; Ju Yeong Kim; Isabel J. L. Baken; Catarina Mendes Silva; Tom P. L. Bijl; Jacqueline van Rijswijk; Judith A. Burger; Albert Cupo; Anila Yasmeen; Swastik Phulera; Wen-Hsin Lee; Kipchoge N. Randall; Shiyu Zhang; Martin M. Corcoran; Isabel Regadas; Alex C. Sullivan; David M. Brown; Jennifer A. Bohl; Kelli M. Greene; Hongmei Gao; Nicole L. Yates; Sheetal Sawant; Jan M. Prins; Neeltje A. Kootstra; Stephen M. Kaminsky; Burc Barin; Farhad Rahaman; Margaret Meller; Vince Philiponis; Dagna S. Laufer; Angela Lombardo; Lindsey Mwoga; Solmaz Shotorbani; Drienna Holman; Richard A. Koup; Per Johan Klasse; Gunilla B. Karlsson Hedestam; Georgia D. Tomaras; Marit J. van Gils; David C. Montefiori; Adrian B. McDermott; Ollivier Hyrien; John P. Moore; Ian A. Wilson; Andrew B. Ward; David J. Diemert; Godelieve J. de Bree; Sarah F. Andrews; Marina Caskey; Rogier W. Sanders

Vaccination with mRNA-encoded nanoparticles drives early maturation of HIV bnAb precursors in humans mRNA编码的纳米颗粒疫苗接种可驱动人类HIV广谱中和抗体前体早期成熟

Science

IF45.8

2025-05-15

PREAI

Jordan R. Willis; Madhu Prabhakaran; Michelle Muthui; Ansuya Naidoo; Troy Sincomb; Weiwei Wu; Christopher A. Cottrell; Elise Landais; Allan C. deCamp; Nahid R. Keshavarzi; Oleksandr Kalyuzhniy; Jeong Hyun Lee; Linda M. Murungi; Wilfrida A. Ogonda; Nicole L. Yates; Martin M. Corcoran; Swastik Phulera; Joel Musando; Amanda Tsai; Gabrielle Lemire; Yiakon Sein; Michael Muteti; Praveen Alamuri; Jennifer A. Bohl; Drienna Holman; Sunny Himansu; Brett Leav; Caroline Reuter; Li-An Lin; Baoyu Ding; Chunla He; Walter L. Straus; Kellie J. MacPhee; Isabel Regadas; Diana V. Nyabundi; Ruth Chirchir; Omu Anzala; John N. Kimotho; Caleb Kibet; Kelli Greene; Hongmei Gao; Erica Beatman; Kiara Benson; Dominick Laddy; David M. Brown; Rhianna Bronson; Jalen Jean-Baptiste; Suprabhath Gajjala; Zahra Rikhtegaran-Tehrani; Alison Benner; Mukundhan Ramaswami; Danny Lu; Nushin Alavi; Sonya Amirzehni; Michael Kubitz; Ryan Tingle; Erik Georgeson; Nicole Phelps; Yumiko Adachi; Alessia Liguori; Claudia Flynn; Katherine McKenney; Xiaoya Zhou; D. Collins Owuor; Sharon A. Owuor; Soo-Young Kim; Michael Duff; Ju Yeong Kim; Grace Gibson; Sabyasachi Baboo; Jolene Diedrich; Torben Schiffner; Marisa Shields; Mabela Matsoso; Jennifer Santos; Kristen Syvertsen; Allison Kennedy; Melissa Schroeter; Johan Vekemans; John R. Yates; James C. Paulson; Ollivier Hyrien; Adrian B. McDermott; Pholo Maenetje; Julien Nyombayire; Etienne Karita; Rosine Ingabire; Vinodh Edward; Vincent Muturi-Kioi; Janine Maenza; Adrienne E. Shapiro; M. Juliana McElrath; Srilatha Edupuganti; Barbara S. Taylor; David Diemert; Gabriel Ozorowski; Richard A. Koup; David Montefiori; Andrew B. Ward; Gunilla B. Karlsson Hedestam; Georgia Tomaras; Devin J. Hunt; Daniel Muema; Devin Sok; Dagna S. Laufer; Sarah F. Andrews; Eunice W. Nduati; William R. Schief

Virologic effects of broadly neutralizing antibodies VRC01LS and VRC07-523LS on chronic HIV-1 infection

JCI INSIGHT

IF6.1

2025-02-24

OAAI

Happe, Myra; Lynch, Rebecca M.; Fichtenbaum, Carl J.; Heath, Sonya L.; Koletar, Susan L.; Landovitz, Raphael J.; Presti, Rachel M.; Santana-Bagur, Jorge L.; Tressler, Randall L.; Holman, LaSonji A.; Novik, Laura; Roa, Jhoanna C.; Rothwell, Ro Shauna; Strom, Larisa; Wang, Jing; Hu, Zonghui; Conan-Cibotti, Michelle; Bhatnagar, Anjali M.; Dwyer, Bridget; Ko, Sung Hee; Belinky, Frida; Namboodiri, Aryan M.; Pandey, Janardan P.; Carroll, Robin; Basappa, Manjula; Serebryannyy, Leonid; Narpala, Sandeep R.; Lin, Bob C.; Mcdermott, Adrian B.; Boritz, Eli A.; Capparelli, Edmund V.; Coates, Emily E.; Koup, Richard A.; Ledgerwood, Julie E.; Mascola, John R.; Chen, Grace L.; Tebas, Pablo

Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350 通过Epstein-Barr病毒gp350介导补体受体结合及病毒中和的结构基础

IMMUNITY

IF26.3

2025-02-01

OAAI

Joyce, M. Gordon; Bu, Wei; Chen, Wei-Hung; Gillespie, Rebecca A.; Andrews, Sarah F.; Wheatley, Adam K.; Tsybovsky, Yaroslav; Jensen, Jaime L.; Stephens, Tyler; Prabhakaran, Madhu; Fisher, Brian E.; Narpala, Sandeep R.; Bagchi, Meghna; Mcdermott, Adrian B.; Nabel, Gary J.; Kwong, Peter D.; Mascola, John R.; Cohen, Jeffrey I.; Kanekiyo, Adrian Masaru

Early influenza virus exposure shapes the B cell response to influenza vaccination in individuals 50 years later 早期流感病毒暴露塑造了50年后个体对流感疫苗接种的B细胞反应

IMMUNITY

IF26.3

2025-02-01

PREAI

Spangler, Abby; Shimberg, Geoffrey D.; Mantus, Grace E.; Malek, Rory; Cominsky, Lauren Y.; Tsybovsky, Yaroslav; Li, Ning; Gillespie, Rebecca A.; Ravichandran, Michelle; Creanga, Adrian; Raab, Julie E.; Gajjala, Suprabhath R.; Mendoza, Floreliz; V. Houser, Katherine; Dropulic, Lesia; Mcdermott, Adrian B.; Kanekiyo, Masaru; Andrews, Sarah F.

Enhanced and sustained biodistribution of HIV-1 neutralizing antibody VRC01LS in human genital and rectal mucosa

NATURE COMMUNICATIONS

IF15.7

2024-11-28

OAAI

Lemos, Maria P.; Astronomo, Rena D.; Huang, Yunda; Narpala, Sandeep; Prabhakaran, Madhu; Mann, Philipp; Paez, Carmen A.; Lu, Yiwen; Mize, Gregory J.; Glantz, Hayley; Westerberg, Katharine; Colegrove, Hunter; Smythe, Kimberly S.; Lin, Minggang; Pierce, Robert H.; Hutter, Julia; Frank, Ian; Mascola, John R.; Mcdermott, Adrian B.; Bekker, Linda-Gail; Mcelrath, M. Juliana

Phase 1 dose-escalation trial evaluating a group 2 influenza hemagglutinin stabilized stem nanoparticle vaccine

NPJ VACCINES

IF6.5

2024-09-17

OAAI

Casazza, Joseph P.; Hofstetter, Amelia R.; Costner, Pamela J. M.; Holman, LaSonji A.; Hendel, Cynthia S.; Widge, Alicia T.; Wu, Richard L.; Whalen, William R.; Cunningham, Jennifer; Arthur, Anita; Wang, Xiaolin; Ola, Abidemi; Saunders, Jamie; Mendoza, Floreliz; Novik, Laura; Burgos Florez, Maria C.; Ortega-Villa, Ana M.; Apte, Preeti J.; Strom, Larisa; Wang, Lu; Imam, Marjaan; Basappa, Manjula; Naisan, Mursal; Castro, Mike; Trost, Jessica F.; Narpala, Sandeep R.; Vanderven, Hillary A.; Yamshchikov, Galina V.; Berkowitz, Nina M.; Gordon, Ingelise J.; Plummer, Sarah H.; Wycuff, Diane L.; Vazquez, Sandra; Gillespie, Rebecca A.; Creanga, Adrian; Adams, William C.; Carlton, Kevin; Gall, Jason G.; Mcdermott, Adrian B.; Serebryannyy, Leonid A.; Houser, Katherine V.; Koup, Richard A.; Graham, Barney S.; Ledgerwood, Julie E.; Mascola, John R.; Pierson, Theodore C.; Andrews, Sarah F.; Kanekiyo, Masaru; Dropulic, Lesia K.

Safety and antiviral effect of a triple combination of HIV-1 broadly neutralizing antibodies: a phase 1/2a trial

NATURE MEDICINE

IF50

2024-09-12

OAAI

Julg, Boris; Walker-Sperling, Victoria E. K.; Wagh, Kshitij; Aid, Malika; Stephenson, Kathryn E.; Zash, Rebecca; Liu, Jinyan; Nkolola, Joseph P.; Hoyt, Amelia; Castro, Mike; Serebryannyy, Leonid; Yanosick, Katherine; Speidel, Tessa; Borducchi, Erica N.; Murzda, Tetyana; Maxfield, Lori; Arduino, Roberto; Mcdermott, Adrian B.; Gama, Lucio; Giorgi, Elena E.; Koup, Richard A.; Seaman, Michael S.; Rolle, Charlotte-Paige; Dejesus, Edwin; Li, Wenjun; Korber, Bette; Barouch, Dan H.

Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site 种系靶向HIV疫苗可诱导CD4结合位点的中和抗体

SCIENCE IMMUNOLOGY

IF16.3

2024-08-30

PREAI

Caniels, Tom G.; Medina-Ramirez, Max; Zhang, Shiyu; Kratochvil, Sven; Xian, Yuejiao; Koo, Ja-Hyun; Derking, Ronald; Samsel, Jakob; van Schooten, Jelle; Pecetta, Simone; Lamperti, Edward; Yuan, Meng; Carrasco, Maria Rios; del Moral Sanchez, Ivan; Allen, Joel D.; Bouhuijs, Joey H.; Yasmeen, Anila; Ketas, Thomas J.; Snitselaar, Jonne L.; Bijl, Tom P. L.; Martin, Isabel Cuella; Torres, Jonathan L.; Cupo, Albert; Shirreff, Lisa; Rogers, Kenneth; Mason, Rosemarie D.; Roederer, Mario; Greene, Kelli M.; Gao, Hongmei; Silva, Catarina Mendes; Baken, Isabel J. L.; Tian, Ming; Alt, Frederick W.; Pulendran, Bali; Seaman, Michael S.; Crispin, Max; van Gils, Marit J.; Montefiori, David C.; McDermott, Adrian B.; Villinger, Francois J.; Koup, Richard A.; Moore, John P.; Klasse, Per Johan; Ozorowski, Gabriel; Batista, Facundo D.; Wilson, Ian A.; Ward, Andrew B.; Sanders, Rogier W.

Anti-idiotype isolation of a broad and potent influenza A virus-neutralizing human antibody

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-05-30

OAAI

Olia, Adam S.; Prabhakaran, Madhu; Harris, Darcy R.; Cheung, Crystal Sao-Fong; Gillespie, Rebecca A.; Gorman, Jason; Hoover, Abigayle; Morano, Nicholas C.; Ourahmane, Amine; Srikanth, Abhinaya; Wang, Shuishu; Wu, Weiwei; Zhou, Tongqing; Andrews, Sarah F.; Kanekiyo, Masaru; Shapiro, Lawrence; Mcdermott, Adrian B.; Kwong, Peter D.

Subcutaneous Administration of a Monoclonal Antibody to Prevent Malaria

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2024-05-02

OAAI

Kayentao, Kassoum; Ongoiba, Aissata; Preston, Anne C.; Healy, Sara A.; Hu, Zonghui; Skinner, Jeff; Doumbo, Safiatou; Wang, Jing; Cisse, Hamidou; Doumtabe, Didier; Traore, Abdrahamane; Traore, Hamadi; Djiguiba, Adama; Li, Shanping; Peterson, Mary E.; Telscher, Shinyi; Idris, Azza H.; Adams, William C.; McDermott, Adrian B.; Narpala, Sandeep; Lin, Bob C.; Serebryannyy, Leonid; Hickman, Somia P.; McDougal, Andrew J.; Vazquez, Sandra; Reiber, Matthew; Stein, Judy A.; Gall, Jason G.; Carlton, Kevin; Schwabl, Philipp; Traore, Siriman; Keita, Mamadou; Zeguime, Amatigue; Ouattara, Adama; Doucoure, M'Bouye; Dolo, Amagana; Murphy, Sean C.; Neafsey, Daniel E.; Portugal, Silvia; Djimde, Abdoulaye; Traore, Boubacar; Seder, Robert A.; Crompton, Peter D.

Immune memory shapes human polyclonal antibody responses to H2N2 vaccination 免疫记忆塑造人多克隆抗体对H2N2疫苗接种的反应

CELL REPORTS

IF6.9

2024-05-01

OAAI

Yang, Yuhe R.; Han, Julianna; Perrett, Hailee R.; Richey, Sara T.; Rodriguez, Alesandra J.; Jackson, Abigail M.; Gillespie, Rebecca A.; O'Connell, Sarah; Raab, Julie E.; Cominsky, Lauren Y.; Chopde, Ankita; Kanekiyo, Masaru; Houser, Katherine V.; Chen, Grace L.; McDermott, Adrian B.; Andrews, Sarah F.; Ward, Andrew B.

Impact of LS Mutation on Pharmacokinetics of Preventive HIV Broadly Neutralizing Monoclonal Antibodies: A Cross-Protocol Analysis of 16 Clinical Trials in People without HIV

PHARMACEUTICS

IF5.5

2024-04-27

OAAI

Mayer, Bryan T.; Zhang, Lily; Decamp, Allan C.; Yu, Chenchen; Sato, Alicia; Angier, Heather; Seaton, Kelly E.; Yates, Nicole; Ledgerwood, Julie E.; Mayer, Kenneth; Caskey, Marina; Nussenzweig, Michel; Stephenson, Kathryn; Julg, Boris; Barouch, Dan H.; Sobieszczyk, Magdalena E.; Edupuganti, Srilatha; Kelley, Colleen F.; Mcelrath, M. Juliana; Gelderblom, Huub C.; Pensiero, Michael; McDermott, Adrian; Gama, Lucio; Koup, Richard A.; Gilbert, Peter B.; Cohen, Myron S.; Corey, Lawrence; Hyrien, Ollivier; Tomaras, Georgia D.; Huang, Yunda

C1q enables influenza hemagglutinin stem binding antibodies to block viral attachment and broadens the antibody escape repertoire

SCIENCE IMMUNOLOGY

IF16.3

2024-03-22

PREAI

Kosik, Ivan; Santos, Jefferson Da Silva; Angel, Mathew; Hu, Zhe; Holly, Jaroslav; Gibbs, James S.; Gill, Tanner; Kosikova, Martina; Li, Tiansheng; Bakhache, William; Dolan, Patrick T.; Xie, Hang; Andrews, Sarah F.; Gillespie, Rebecca A.; Kanekiyo, Masaru; Mcdermott, Adrian B.; Pierson, Theodore C.; Yewdell, Jonathan W.

Human immunoglobulin gene allelic variation impacts germline-targeting vaccine priming

NPJ VACCINES

IF6.5

2024-03-11

OAAI

Decamp, Allan C.; Corcoran, Martin M.; Fulp, William J.; Willis, Jordan R.; Cottrell, Christopher A.; Bader, Daniel L. V.; Kalyuzhniy, Oleksandr; Leggat, David J.; Cohen, Kristen W.; Hyrien, Ollivier; Menis, Sergey; Finak, Greg; Ballweber-Fleming, Lamar; Srikanth, Abhinaya; Plyler, Jason R.; Rahaman, Farhad; Lombardo, Angela; Philiponis, Vincent; Whaley, Rachael E.; Seese, Aaron; Brand, Joshua; Ruppel, Alexis M.; Hoyland, Wesley; Mahoney, Celia R.; Cagigi, Alberto; Taylor, Alison; Brown, David M.; Ambrozak, David R.; Sincomb, Troy; Mullen, Tina-Marie; Maenza, Janine; Kolokythas, Orpheus; Khati, Nadia; Bethony, Jeffrey; Roederer, Mario; Diemert, David; Koup, Richard A.; Laufer, Dagna S.; McElrath, Juliana M.; McDermott, Adrian B.; Hedestam, Gunilla B. Karlsson; Schief, William R.

研究方向