Hidetoshi Tokuyama - Publications, H-index & Citations

Hidetoshi Tokuyama

Tohoku University

52H指数

331论文数

9.0K被引数

收录论文 87

发表时间

Identification of a novel small-molecule compound that suppresses depolarization-induced CYP11B2 expression and aldosterone production in KCNJ5 mutant adrenocortical cells 鉴定一种新型小分子化合物，该化合物可抑制KCNJ5突变肾上腺皮质细胞中除极化诱导的CYP11B2表达和醛固酮产生

Biochemical and Biophysical Research Communications

IF2.2

2026-09-12

OAAI

Yuri Otsubo; Hiroki Shimada; Keita Hoshi; Ryo Ito; Thanh Phuong Nguyen; Hiroyuki Yamakoshi; Kosuke Ohsawa; Hirofumi Ueda; Hidetoshi Tokuyama; Yoshiro Saito; Yoshiharu Iwabuchi; Takayuki Doi; Yasuhiro Nakamura; Akira Sugawara; Atsushi Yokoyama

Synthesis of Mirabegron via Late-Stage Cu-Catalyzed Aromatic Amidation 通过晚期Cu催化的芳基酰胺化合成Mirabegron

CHEMICAL & PHARMACEUTICAL BULLETIN

IF1.3

2026-05-01

PREAI

Teraji, Honoka; Kanai, Shuga; Ojima, Ken-ichi; Kosuge, Shuto; Ueda, Hirofumi; Tokuyama, Hidetoshi

Divergent Total Synthesis of Denudatine Alkaloids Cochlearenine, Macrocentrine, Dictizine, 15-Veratroyl-17-Acetyl-19-Oxodictizine, and the Proposed Structure of Acochlearine 不同路线的全合成：Denudatine生物碱Cochlearenine、Macrocentrine、Dictizine、15-Veratroyl-17-Acetyl-19-Oxodictizine以及Acochlearine的提议结构

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2025-12-01

OAAI

Kawano, Shun; Miyamoto, Naoya; Fujioka, Kosuke; Toya, Hiroki; Sakata, Juri; Tokuyama, Hidetoshi

Aerobic Oxidative Dethioacetalization Catalyzed by an Iron Phthalocyanine Complex 由铁酞菁配合物催化的有氧氧化硫缩醛分解反应

ADVANCED SYNTHESIS & CATALYSIS

IF4

2025-11-01

OAAI

Ueda, Hirofumi; Sato, Ryo; Machii, Hayato; Kobayashi, Nagao; Tokuyama, Hidetoshi

Concise Total Synthesis of (±)-Makaluvamine F and Its Derivatives (±)-Makaluvamine F及其衍生物的简洁全合成

CHEMICAL & PHARMACEUTICAL BULLETIN

IF1.3

2025-10-01

OAAI

Shimomura, Masashi; Kanno, Yusuke; Kitao, Shunta; Horie, Manaka; Ide, Kohta; Sakata, Juri; Tokuyama, Hidetoshi

Synthesis of 2-Phosphorus-Substituted Indoles via Ring Expansion of Benzocyclobutenone Oxime Sulfonates 通过苯并环丁酮肟磺酸盐环扩大合成2-膦取代的吲哚类化合物

Organic Letters

IF5

2025-05-29

OAAI

Yusuke Kanno; Yumi Yamashita; Akira Sugiyama; Tatsuhiko Kodama; Juri Sakata; Hidetoshi Tokuyama

Semisynthetic Studies Establish a Role for Conjugate Halide Exchange in the Formation of Chlorinated Pyrroloiminoquinones and Related Alkaloids

JOURNAL OF NATURAL PRODUCTS

IF3.6

2024-09-30

PREAI

Sala, Samuele; Shimomura, Masashi; Tham, Louisa; Sakata, Juri; Sobolev, Alexandre N.; Moggach, Stephen A.; Fromont, Jane; Gomez, Oliver; Piggott, Matthew J.; Tokuyama, Hidetoshi; Stewart, Scott G.; Flematti, Gavin R.

Unified Divergent Total Synthesis of Discorhabdin B, H, K, and Aleutianamine via the Late-Stage Oxidative N,S-Acetal Formation

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-08-09

PREAI

Shimomura, Masashi; Ide, Kohta; Sakata, Juri; Tokuyama, Hidetoshi

Concise Total Synthesis of (+)-Pleiocarpamine and Convergent Total Syntheses of (+)-Voacalgine A and (+)-Bipleiophylline via an Aerobic Oxidative Coupling

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-07-24

PREAI

Okada, Kosuke; Ojima, Ken-ichi; Ueda, Hirofumi; Tokuyama, Hidetoshi

Synthetic Studies on Cimiciduphytine

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

IF3.8

2023-05-02

PREAI

Ojima, Ken-ichi; Ueda, Hirofumi; Tokuyama, Hidetoshi; Iyag, M.

Efficient and Scalable Asymmetric Total Synthesis of (-)-Emetine with Pharmaceutical Grade Quality; First Multigram Scale Synthesis

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2023-01-24

PREAI

Yamada, Masatoshi; Azuma, Kazuki; Takizawa, Iori; Ejima, Yuki; Yamano, Mitsuhisa; Satoh, Kimio; Doi, Takayuki; Ueda, Hirofumi; Tokuyama, Hidetoshi

A Concise Enantioselective Total Synthesis of (-)-Deoxoapodine (-)-脱氧阿普定的简明对映选择性全合成

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2020-10-15

PREAI

Yoshida, Kei; Okada, Kosuke; Ueda, Hirofumi; Tokuyama, Hidetoshi

Aerobic Dehydrogenation ofN-Heterocycles with Grubbs Catalyst: Its Application to Assisted-Tandem Catalysis to ConstructN-Containing Fused Heteroarenes

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2020-10-06

PREAI

Kawauchi, Daichi; Noda, Kenta; Komatsu, Yoshiyuki; Yoshida, Kei; Ueda, Hirofumi; Tokuyama, Hidetoshi

Nitrile Synthesis by Aerobic Oxidation of Primary Amines and in situ Generated Imines from Aldehydes and Ammonium Salt with Grubbs Catalyst 用Grubbs催化剂通过醛和铵盐有氧氧化伯胺和原位生成的亚胺合成腈

ADVANCED SYNTHESIS & CATALYSIS

IF4

2020-07-31

PREAI

Utsumi, Tatsuki; Noda, Kenta; Kawauchi, Daichi; Ueda, Hirofumi; Tokuyama, Hidetoshi

Divergent Total Syntheses of Isobatzellines A/B and Batzelline A

ORGANIC LETTERS

IF5

2020-07-05

PREAI

Yamashita, Yumi; Poignant, Louna; Sakata, Juri; Tokuyama, Hidetoshi

Total Synthesis of (-)-Lepadiformine A via Radical Translocation-Cyclization Reaction

ORGANIC LETTERS

IF5

2020-03-17

PREAI

Shimomura, Masashi; Sato, Manabu; Azuma, Hiroki; Sakata, Juri; Tokuyama, Hidetoshi

Identification of Emetine as a Therapeutic Agent for Pulmonary Arterial Hypertension Novel Effects of an Old Drug

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2019-11-01

OAAI

Siddique, Mohammad Abdul Hai; Satoh, Kimio; Kurosawa, Ryo; Kikuchi, Nobuhiro; Elias-Al-Mamun, Md.; Omura, Junichi; Satoh, Taijyu; Nogi, Masamichi; Sunamura, Shinichiro; Miyata, Satoshi; Ueda, Hirofumi; Tokuyama, Hidetoshi; Shimokawa, Hiroaki

Fluorescent Labeling Method Re-Evaluates the Intriguing Thermoresponsive Behavior of Poly(acrylamide-co-acrylonitrile)s with Upper Critical Solution Temperatures

MACROMOLECULES

IF5.2

2019-10-03

PREAI

Otsuka, Chie; Wakahara, Yuko; Okabe, Kohki; Sakata, Juri; Okuyama, Masaki; Hayashi, Akinobu; Tokuyama, Hidetoshi; Uchiyama, Seiichi

Total Synthesis of (+)-CC-1065 Utilizing Ring Expansion Reaction of Benzocyclobutenone Oxime Sulfonate

ORGANIC LETTERS

IF5

2019-06-12

PREAI

Imaizumi, Taku; Yamashita, Yumi; Nakazawa, Yuki; Okano, Kentaro; Sakata, Juri; Tokuyama, Hidetoshi