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M

M. Isabel Lucena

centro de investigacion en red en el area tematica de enfermedades hepaticas y digestivas

59H指数
378论文数
1.3W被引数
收录论文 171
发表时间
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Risk of drug-induced liver injury in multiple system atrophy patients treated with KM-819 is potentially associated with the HLA-DPB1*05:01:01:01 allele多系统萎缩患者使用KM-819治疗时发生药物性肝损伤的风险可能与HLA-DPB1*05:01:01:01等位基因相关
errPharmacogenomics Journal
IF2.9
err2026-09-28
err0
errOAAI
errJeong-Hoon Han; Raúl J. Andrade; Einar Stefán Björnsson; James Hendricks Lewis; M. Isabel Lucena; Suyoung Go; Simona Stankeviciute; Guruprasad P. Aithal; Kyuchan Kim; Chong Sik Lee; Carrolee Barlow; Eunhee Kim
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Beyond Hy's Law: Importance of Markedly Elevated Aminotransferases without Hyperbilirubinemia超越Hy's定律：显著升高的转氨酶无高胆红素血症的重要性
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2026-08-27
err0
PREAI
errNaga Chalasani; Ismael Alvarez-Alvarez; Paul H. Hayashi; Raj Vuppalanchi; Marwan Ghabril; Ronald Kamusiime; Huiman Barnhart; Hao Niu; M. Isabel Lucena; Raul J. Andrade; for the Drug Induced Liver Injury Network
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Clinical Trial Registration and Transparency in No 536/2014:Europe under Regulation (EU): Registry Ecosystems and a Five-Country Comparative Analysis, 2022-2026临床试验注册与透明度在No 536/2014号欧盟法规下的欧洲：注册生态系统和五个国家的比较分析，2022-2026
errMedicina Clinica
IF2.1
err2026-07-01
err0
PREAI
errMoreno-Gonzalez, Rocio; Garrido-Rodriguez, Vanesa; Cardenas-Quesada, Jose; Nogueiras-Alvarez, Rita; Lucena, M. Isabel; Sanabria-Cabrera, Judith
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HLA-B*44 Alleles and HLA-DQA1*03:01 as Genetic Risk Factors for Drug-Induced Liver Injury due to FluoroquinolonesHLA-B*44等位基因和HLA-DQA1*03:01作为氟喹诺酮类药物所致药物性肝损伤的遗传危险因素
errLiver International
IF5.2
err2026-05-15
err0
errOAAI
errPaola Nicoletti; M. Isabel Lucena; Raul J. Andrade; Samreen Zafer; Einar S. Bjornsson; Pär Hallberg; Dominique Larrey; Mariam Molokhia; Mia Wadelius; Guruprasad P. Aithal; Ann K. Daly
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Clinical course and prognostic risk factors of SARS-CoV-2 vaccine-related hepatitis: differentiating severe acute respiratory syndrome coronavirus 2 vaccine-associated liver injury from autoimmune hepatitisSARS-CoV-2疫苗接种相关肝炎的临床过程和预后危险因素：区分严重急性呼吸综合征冠状病毒2疫苗相关肝损伤与自身免疫性肝炎
errEUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
IF1.8
err2026-05-01
err0
PREAI
errMalino, Donald; Codoni, Greta; Kirchner, Theresa; Engel, Bastian; Villamil, Alejandra Maria; Efe, Cumali; Stattermayer, Albert Friedrich; Weltzsch, Jan Philipp; Sebode, Marcial; Bernsmeier, Christine; Lleo, Ana; Gevers, Tom J. G.; Kupcinskas, Limas; Castiella, Agustin; Pinazo, Jose; De Martin, Eleonora; Bobis, Ingrid; Sandahl, Thomas Damgaard; Pedica, Federica; Invernizzi, Federica; Del Poggio, Paolo; Bruns, Tony; Kolev, Mirjam; Semmo, Nasser; Bessone, Fernando; Giguet, Baptiste; Poggi, Guido; Ueno, Masayuki; Jang, Helena; Elpek, Gulsum Ozlem; Soylu, Nese Karadag; Cerny, Andreas; Wedemeyer, Heiner; Matter, Matthias S.; Uzun, Sarp; Matilla-Cabello, Gonzalo; Vergani, Diego; Mieli-Vergani, Giorgina; Lucena, M. Isabel; Andrade, Raul J.; Zen, Yoh; Taubert, Richard; Beretta-Piccoli, Benedetta Terziroli
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The gut–liver axis in drug-induced liver injury (DILI): Interplay between gut microbiota, intestinal barrier, and immune system药物诱导性肝损伤（DILI）中的肠-肝轴：肠道菌群、肠道屏障与免疫系统的相互作用
errActa Pharmaceutica Sinica B
IF14.6
err2026-04-24
err0
errOAAI
errIrene Díaz-Alberola; Daniel E. Di Zeo-Sánchez; Vanesa Garrido-Rodríguez; Carlos López-Gómez; Cristina Rodríguez-Díaz; Raul J. Andrade; M. Isabel Lucena; Marina Villanueva-Paz; Eduardo García-Fuentes
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Usefulness of plasma bile acid profile as a prognostic biomarker for drug-induced liver injury血浆胆汁酸谱作为药物性肝损伤预后生物标志物的实用性
errEBioMedicine
IF10.8
err2026-03-24
err0
errOAAI
errMaria J. Monte; Thi Dong-Binh Tran; Jane I. Grove; Dingzhou Li; Camilla Stephens; M. Isabel Lucena; Raúl J. Andrade; Sabine Weber; Alexander Gerbes; Einar S. Bjornsson; Guido Stirnimann; Helgi K. Bjornsson; Ann K. Daly; Anthony Evans; Shashi K. Ramaiah; Sara A. Paciga; Melanie Lingaya; Edmond Atallah; Mercedes Robles-Diaz; Sophia L. Samodelov
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Systematic review on genetic polymorphisms associated with idiosyncratic drug-induced liver injury (DILI): iDILInet as an interactive visualization tool关于与特应性药物诱导性肝损伤（DILI）相关的遗传多态性的系统综述：iDILInet作为一个交互式可视化工具
errActa Pharmaceutica Sinica B
IF14.6
err2026-03-23
err0
errOAAI
errGonzalo Matilla-Cabello; Ángela Remesal-Doblado; Muazzez Celebi-Cinar; Ana Bodoque-García; Fatma Betul Metin; Aida Rezaei; Moiz Aftab; Romina De los Santos-Fernández; Antonio Segovia-Zafra; Ismael Álvarez-Álvarez; Raúl J. Andrade; Gulcin Cakan-Akdogan; M. Isabel Lucena; Ozlen Konu; Marina Villanueva-Paz
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Sex/gender differences in clinical pharmacology: A perspective from the IUPHAR World Smart Medication Day 2025性/性别差异在临床药理学中的体现：IUPHAR世界智慧用药日2025的视角
errPharmacological Research
IF10.5
err2025-07-28
err0
errOAAI
errM.I. Lucena; P. Galappatthy; K. Allegaert; Y. Böttiger; N.A. Buckley; B. Medhi; M.J. Rieder; C. Waitt; S.N. Hilmer
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Evaluation of the role of comedication properties in the severity of drug-induced liver injury using machine learning techniques使用机器学习技术研究合并用药特性在药物性肝损伤严重程度中的作用评估
errExpert Opinion on Drug Metabolism & Toxicology
IF3.4
err2025-07-06
err0
PREAI
errIrene Victoria Bermúdez-Pérez; Ismael Alvarez-Alvarez; Inmaculada Medina-Cáliz; Mercedes Robles-Diaz; Hao Niu; Minjun Chen; Raúl J. Andrade; Mª Isabel Lucena; Camilla Stephens; Andrés Gonzalez-Jimenez
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Stanozolol-induced Liver Injury: A Distinctive Cholestatic Clinical and Biochemical Phenotype at Presentation
errclinical and experimental pediatrics
IF3.2
err2025-05-01
err0
PREAI
errNunes, Vinicius; Schinoni, Maria I.; Bessone, Fernando; Lucena, Maria I.; Medina-Caliz, Inmaculada; Hernandez, Nelia; Costa, Maria C. Moura; Lins, Isadora; Cardoso, Ana J.; Freire, Barbara; Schiavon, Leonardo; Silva, Marcelo; Cancado, Eduardo R.; Parana, Raymundo
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Epigenetic modifications in drug-induced liver injury: A systematic review表观遗传修饰在药物性肝损伤中的系统评价
errBRITISH JOURNAL OF CLINICAL PHARMACOLOGY
IF3
err2025-03-01
err0
PREAI
errde los Santos-Fernandez, Romina Lorena; Segovia-Zafra, Antonio; Paz-Lopez, Guillermo; Matilla-Cabello, Gonzalo; Niu, Hao; alvarez-alvarez, Ismael; Stephens, Camilla; Gonzalez-Jimenez, Andres; Lucena, M. Isabel; Andrade, Raul J.; Medina-Caliz, Inmaculada
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Genetic Variants of GBP4: Reduced Risks for Drug-Induced Acute Liver Failure in Non-Finnish European PopulationGBP4的遗传变异: 降低非芬兰欧洲人群药物诱导的急性肝衰竭的风险
errLIVER INTERNATIONAL
IF5.2
err2025-01-27
err0
PREAI
errLiao, Tsung-Jen; Xia, Menghang; Hayashi, Paul; Pan, Bohun; Aithal, Guruprasad P.; Lucena, M. Isabel; Andrade, Raul J.; Rule, Jody A.; Lee, William M.; Rakela, Jorge; Huang, Ruili; Chen, Minjun
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Reply to: Correspondence on 'Control compounds for driven systematic review by the ProEuroDILI network'回复：关于《ProEuroDILI网络驱动的系统综述中的对照化合物》的通信
errJOURNAL OF HEPATOLOGY
IF33
err2024-12-01
err0
PREAI
errSegovia-Zafra, Antonio; Lucena, M. Isabel; Andrade, Raul J.
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Control compounds for preclinical drug-induced liver injury assessment: Consensus-driven systematic review by the ProEuroDILI network
errJOURNAL OF HEPATOLOGY
IF33
err2024-10-01
err2
errOAAI
errSegovia-Zafra, Antonio; Villanueva-Paz, Marina; Serras, Ana Sofia; Matilla-Cabello, Gonzalo; Bodoque-Garcia, Ana; Zeo-Sanche, Daniel E. Di; Niu, Hao; Alvarez-Alvarez, Ismael; Sanz-Villanueva, Laura; Godec, Sergej; Milisav, Irina; Bagnaninchi, Pierre; Andrade, Raul J.; Lucena, M. Isabel; Fernandez-Checa, Jose C.; Cubero, Francisco Javier; Miranda, Joana Paiva; Nelson, Leonard J.
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Methods for causality assessment of idiosyncratic drug-induced liver injury
errLIVER INTERNATIONAL
IF5.2
err2024-08-21
err1
errOAAI
errGarcia-Cortes, Miren; Matilla-Cabello, Gonzalo; Lucena, M. Isabel
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Special Issue Spanish Basic and Clinical Pharmacology
errPHARMACOLOGICAL RESEARCH
IF10.5
err2024-08-01
err0
errOAAI
errCena, Valentin; Lucena, M. Isabel
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Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway
errCELL REPORTS MEDICINE
IF10.6
err2024-07-01
err1
errOAAI
errGil-Pitarch, Claudia; Serrano-Macia, Marina; Simon, Jorge; Mosca, Laura; Conter, Carolina; Rejano-Gordillo, Claudia M.; Zapata-Pavas, L. Estefania; Pena-Sanfelix, Patricia; Azkargorta, Mikel; Rodriguez-Agudo, Ruben; Lachiondo-Ortega, Sofia; Mercado-Gomez, Maria; Delgado, Teresa C.; Porcelli, Marina; Aurrekoetxea, Igor; Sutherland, James D.; Barrio, Rosa; Xirodimas, Dimitris; Aspichueta, Patricia; Elortza, Felix; Martinez-Cruz, Luis Alfonso; Nogueiras, Ruben; Iruzubiet, Paula; Crespo, Javier; Masson, Steven; McCain, Misti Vanette; Reeves, Helen L.; Andrade, Raul J.; Isabel Lucena, M.; Mayor, Ugo; Goikoetxea-Usandizaga, Naroa; Gonzalez-Recio, Irene; Martinez-Chantar, Maria L.
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Reply to: Distinction of autoimmune hepatitis from drug-induced autoimmune like hepatitis: The answer lies at the interface回复: 自身免疫性肝炎与药物诱导的自身免疫性肝炎的区别: 答案在于界面
errJOURNAL OF HEPATOLOGY
IF33
err2024-07-01
err0
PREAI
errBjornsson, Einar S.; Lucena, M. Isabel; Andrade, Raul J.
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Rechallenge in idiosyncratic drug-induced liver injury: An analysis of cases in two large prospective registries according to existing definitions特异质性药物性肝损伤的再次暴露：基于现有定义对两项大型前瞻性登记研究中病例的分析
errPHARMACOLOGICAL RESEARCH
IF10.5
err2024-05-01
err2
errOAAI
errPinazo-Bandera, J. M.; Niu, H.; Alvarez-Alvarez, I.; Medina-Caliz, I.; Campo-Herrera, E. Del; Ortega-Alonso, A.; Robles-Diaz, M.; Hernandez, N.; Parana, R.; Nunes, V.; Girala, M.; Bessone, F.; Lucena, M. I.; Andrade, R. J.; Cortes, M. Garcia
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研究方向

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