未登录Discovery of a Potent, Selective, and Blood-Brain Barrier Permeable Non-nitrocatechol Inhibitor of Catechol-O-methyltransferase
Benfeito, Sofia; Albuquerque, Barbara; Sequeira, Lisa; Lima, Carla; Chavarria, Daniel; Serrao, Paula; Cagide, Fernando; Soares-da-Silva, Patriicio; Borges, Fernanda
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收藏Effect of zamicastat on blood pressure and heart rate response to cold pressor test: A double-blind, randomized, placebo-controlled study in healthy subjects
Fonseca, Marlene; Ribeiro, Cheila; Castilla-Fernandez, Guillermo; Gama, Helena; Magalhaes, Luis; Henriques, Sara Carolina; Silva, Nuno; Pinto, Filipe; Almeida, Luis; Soares-da-Silva, Patricio
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收藏OFF-times before, during, and after nighttime sleep periods in Parkinson's disease patients with motor fluctuations and the effects of opicapone: A post hoc analysis of diary data from BIPARK-1 and-2
Hauser, Robert A.; Videnovic, Aleksandar; Soares-da-Silva, Patricio; Liang, Grace S.; Olson, Kurt; Jen, Eric; Rocha, Jose-Francisco; Klepitskaya, Olga
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收藏Boosting caffeic acid performance as antioxidant and monoamine oxidase B/catechol-O-methyltransferase inhibitor提高咖啡酸作为抗氧化剂和单胺氧化酶B/儿茶酚-O-甲基转移酶抑制剂的性能
Chavarria, Daniel; Benfeito, Sofia; Soares, Pedro; Lima, Carla; Garrido, Jorge; Serra, Paula; Soares-da-Silva, Patricio; Remia, Fernando; Oliveira, Paulo J.; Borges, Fernanda
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收藏Voltage-clamp evidence of GABAA receptor subunit-specific effects: pharmacodynamic fingerprint of chlornordiazepam, the major active metabolite of mexazolam, as compared to alprazolam, bromazepam, and zolpidem
Fernandes, Helder; Batalha, Vania; Braksator, Ellen; Hebeisen, Simon; Bonifacio, Maria Joao; Vieira-Coelho, Maria Augusta; Soares-da-Silva, Patricio
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收藏Opicapone as an Add-on to Levodopa in Patients with Parkinson's Disease Without Motor Fluctuations: Rationale and Design of the Phase III, Double-Blind, Randomised, Placebo-Controlled EPSILON Trial在无运动波动的帕金森病患者中,Opicapone作为左旋多巴的附加物: III期,双盲,随机,安慰剂对照EPSILON试验的原理和设计
Ferreira, Joaquim J.; Poewe, Werner; Rascol, Olivier; Stocchi, Fabrizio; Antonini, Angelo; Moreira, Joana; Pereira, Ana; Rocha, Jose-Francisco; Soares-da-Silva, Patricio
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收藏Absorption, metabolism and excretion of opicapone in human healthy volunteers
Loureiro, Ana, I; Rocha, Francisco; Santos, Ana T.; Singh, Nand; Bonifacio, Maria Joao; Pinto, Rui; Kiss, Laszlo E.; Soares-da-Silva, Patricio
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收藏Adoption (early levodopa with opicapone in Parkinson's patients with motor fluctuations) study in Parkinson's disease: Design and rationale of a randomized prospective, open-label exploratory trial帕金森氏病的采用 (帕金森氏病运动波动患者的早期左旋多巴和opicapone) 研究: 一项随机前瞻性,开放标签探索性试验的设计和原理
Ferreira, Joaquim; Poewe, Werner; Rascol, Olivier; Stocchi, Fabrizio; Antonini, Angelo; Costa, Raquel; Magalhaes, Diogo; Rocha, Jose; Soares-Da-Silva, Patricio
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