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T

Tom Huxford

San Diego State University

H指数:22

被引数:3,369

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Incorporating Metal–Ligand and Salt-Bridge Interactions in the Design of Protein Heterodimers

在蛋白质异源二聚体的设计中纳入金属-配体和盐桥相互作用

IF3

2025-07-110

PRE

Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms

NATURE COMMUNICATIONS

IF15.7

2024-05-060

OAAI

Aging-affiliated post-translational modifications of skeletal muscle myosin affect biochemical properties, myofibril structure, muscle function, and proteostasis

IF7.1

2024-03-201

OAAI

The generation of an engineered HEK293T cell line bearing mutant NEMO incapable of binding to secondary binding site

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-03-010

OAAI

Investigating the protein-protein interactions of Drosophila UNC-45

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-03-010

OAAI

Kinetic and Structural Characterization of Human Isocitrate Dehydrogenase 1

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-01-010

OAAI

Variation in the kinetic parameters and structural features of tumor-driving isocitrate dehydrogenase 1 (IDH1) mutants tune phenotype severity

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-01-010

OAAI

Elucidating protein-protein interactions of Drosophila UNC-45 via in vivo and in vitro chemical crosslinking

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-01-010

OAAI

The generation of an engineered HEK293T cell line bearing mutant NEMO incapable of binding to linear polyubiquitin

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-01-010

OAAI

TWEAK-Fn14-RelB Signaling Cascade Promotes Stem Cell-like Features that Contribute to Post-Chemotherapy Ovarian Cancer Relapse

MOLECULAR CANCER RESEARCH

IF4.7

2022-10-1015

OA

Regulatory subunit NEMO promotes polyubiquitin-dependent induction of NF-κB through a targetable second interaction with upstream activator IKK2

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-05-0115

OAAI

Stapling proteins in the RELA complex inhibits TNFα-induced nuclear translocation of RELA

RSC CHEMICAL BIOLOGY

IF3.1

2022-01-017

OAAI

Small molecule binding to inhibitor of nuclear factor kappa-B kinase subunit beta in an ATP non-competitive manner

CHEMICAL COMMUNICATIONS

IF4.2

2021-01-018

OAAI

Expression and Characterization of the Drosophila melangaster (dm)IKKβ:γ complex

IF4.2

2020-04-190

PRE

Ion Binding Properties of a Naturally Occurring Metalloantibody

IF2.7

2020-04-161

OAAI

Genome reading by the NF-κB transcription factors

NUCLEIC ACIDS RESEARCH

IF13.1

2019-09-1090

OAAI

High-affinity pan-specific monoclonal antibodies that target cysteinyl leukotrienes and show efficacy in an acute model of colitis

JOURNAL OF LIPID RESEARCH

IF4.1

2017-07-016

OAAI

X-Ray Crystallography Structures of Drosophila Striated Muscle Myosin II

BIOPHYSICAL JOURNAL

IF3.1

2017-02-010

OAAI

X-Ray Structure Determination of the First Insect Skeletal Muscle Myosin II

BIOPHYSICAL JOURNAL

IF3.1

2014-01-010

OAAI

Borate as a Synergistic Anion for Marinobacter algicola Ferric Binding Protein, FbpA: A Role for Boron in Iron Transport in Marine Life

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2013-09-199

PREAI