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S

Shiva Malek

roche holding usa
H指数:36
被引数:7,398

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荣誉奖项

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CRAF dimerization with ARAF regulates KRAS-driven tumor growth
CELL REPORTS
IF6.9
2022-02-0119
OA
Venkatanarayan, Avinashnarayan; Liang, Jason; Yen, Ivana; Shanahan, Frances; Haley, Benjamin; Phu, Lilian; Verschueren, Erik; Hinkle, Trent B.; Kan, David; Segal, Ehud; Long, Jason E.; Lima, Tony; Liau, Nicholas P. D.; Sudhamsu, Jawahar; Li, Jason; Klijn, Christiaan; Piskol, Robert; Junttila, Melissa R.; Shaw, Andrey S.; Merchant, Mark; Chang, Matthew T.; Kirkpatrick, Donald S.; Malek, Shiva
RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy

突变体PI3Kα 的RTK依赖性诱导降解驱动GDC-0077 (Inavolisib) 功效

CANCER DISCOVERY
IF33.3
2021-09-2057
OAAI
Song, Kyung W.; Edgar, Kyle A.; Hanan, Emily J.; Hafner, Marc; Oeh, Jason; Merchant, Mark; Sampath, Deepak; Nannini, Michelle A.; Hong, Rebecca; Phu, Lilian; Forrest, William F.; Stawiski, Eric; Schmidt, Stephen; Endres, Nicholas; Guan, Jane; Wallin, Jeffrey J.; Cheong, Jonathan; Plise, Emile G.; Phillips, Gail D. Lewis; Salphati, Laurent; Heffron, Timothy P.; Olivero, Alan G.; Malek, Shiva; Staben, Steven T.; Kirkpatrick, Donald S.; Dey, Anwesha; Friedman, Lori S.
Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5-Fluoro-4-(3H)-quinazolinone Aryl Urea pan-RAF Kinase Inhibitor
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-03-2920
PRE
Huestis, Malcolm P.; Dela Cruz, Darlene; DiPasquale, Antonio G.; Durk, Matthew R.; Eigenbrot, Charles; Gibbons, Paul; Gobbi, Alberto; Hunsaker, Thomas L.; La, Hank; Leung, Dennis H.; Liu, Wendy; Malek, Shiva; Merchant, Mark; Moffat, John G.; Muli, Christine S.; Orr, Christine J.; Parr, Brendan T.; Shanahan, Frances; Sneeringer, Christopher J.; Wang, Weiru; Yen, Ivana; Yin, Jianping; Siu, Michael; Rudolph, Joachim
Discovery of a Noncovalent, Mutant-Selective Epidermal Growth Factor Receptor Inhibitor
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2016-09-1232
PREAI
Chan, Bryan K.; Hanan, Emily J.; Bowman, Krista K.; Bryan, Marian C.; Burdick, Daniel; Chan, Emily; Chen, Yuan; Clausen, Saundra; Dela Vega, Trisha; Dotson, Jennafer; Eigenbrot, Charles; Elliott, Richard L.; Heald, Robert A.; Jackson, Philip S.; Knight, Jamie D.; La, Hank; Lainchbury, Michael D.; Malek, Shiva; Purkey, Hans E.; Schaefer, Gabriele; Schmidt, Stephen; Seward, Eileen M.; Sideris, Steve; Shao, Lily; Wang, Shumei; Yeap, Siew Kuen; Yen, Ivana; Yu, Christine; Heffron, Timothy P.

研究方向

暂未获取到该数据
I
Ivana Yen
H 指数:21论文数:84被引数:3,323
S
Steve Sideris
H 指数:30论文数:97被引数:4,470
G
Gabriele Schaefer
H 指数:27论文数:123被引数:3,404
C
Charles Eigenbrot
H 指数:61论文数:242被引数:1.6万
H
Hank La
H 指数:25论文数:128被引数:2,279
M
Mark Merchant
H 指数:48论文数:380被引数:1.0万
G
Georgia Hatzivassiliou
H 指数:34论文数:117被引数:1.4万
J
Joachim Rudolph
H 指数:37论文数:169被引数:4,897
S
Scott A. Foster
H 指数:38论文数:95被引数:6,777
H
Hans E. Purkey
H 指数:30论文数:67被引数:3,152