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A proteogenomic study of high-grade glioma among adolescents and young adults Tignor, Nicole; Koptyra, Mateusz P.; Chowdhury, Shrabanti; Ma, Weiping; Rokita, Jo Lynne; Gritsenko, Marina; Song, Xiaoyu; Marino, Giacomo B.; Deng, Eden Z.; Petralia, Francesca; Krek, Azra; Rykunov, Dmitry; Leprevost, Felipe da Veiga; Hosseini, Noshad; Rathi, Komal S.; Hu, Yingwei; Migliozzi, Simona; Yaron, Tomer; Fu, Weijia; Zhang, Bo; Zhu, Yuankun; Brown, Miguel A.; Whiteaker, Jeffrey R.; Mesri, Mehdi; Robles, Ana I.; Rodland, Karin; Cantley, Lewis C.; Iavarone, Antonio; Aldape, Kenneth; Cieslik, Marcin; Nesvizhskii, Alexey I.; Ippolito, Joseph E.; Rubin, Joshua B.; Paulovich, Amanda G.; Zhang, Hui; Ma'ayan, Avi; Liu, Tao; Storm, Phillip B.; Resnick, Adam C.; Rood, Brian R.; Wang, Pei 分享 收藏
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Hormone Receptor-Positive Breast Cancer Sensitive to Pembrolizumab: Evidence of the Pathogenicity of the MLH1 Variant 1835del3 Kaplan, Henry G.; Whiteaker, Jeffrey R.; Nelson, Brianna; Ivey, Richard G.; Lorentzen, Travis D.; Voytovich, Uliana; Zhao, Lei; Corwin, David J.; Resta, Robert; Paulovich, Amanda G. 分享 收藏
Monitoring Both Extended and Tryptic Forms of Stable Isotope-Labeled Standard Peptides Provides an Internal Quality Control of Proteolytic Digestion in Targeted Mass Spectrometry-Based Assays 监测稳定同位素标记的标准肽的扩展形式和胰蛋白酶形式,可在基于质谱的靶向测定中对蛋白水解消化进行内部质量控制 Lundeen, Rachel A.; Kennedy, Jacob J.; Murillo, Oscar D.; Ivey, Richard G.; Zhao, Lei; Schoenherr, Regine M.; Hoofnagle, Andrew N.; Wang, Pei; Whiteaker, Jeffrey R.; Paulovich, Amanda G. 分享 收藏
Phase I/II results of ceralasertib as monotherapy or in combination with acalabrutinib in high-risk relapsed/refractory chronic lymphocytic leukemia ceralasertib单药治疗或联合acalabrutinib治疗高危复发/难治性慢性淋巴细胞白血病的I/II期结果 Jurczak, Wojciech; Elmusharaf, Nagah; Fox, Christopher P.; Townsend, William; Paulovich, Amanda G.; Whiteaker, Jeffrey R.; Krantz, Fanny; Wun, Chuan-Chuan; Parr, Graeme; Sharma, Shringi; Munugalavadla, Veerendra; Manwani, Richa; Dean, Emma; Munir, Talha 分享 收藏
A multiplexed assay for quantifying immunomodulatory proteins supports correlative studies in immunotherapy clinical trials Whiteaker, Jeffrey R.; Zhao, Lei; Schoenherr, Regine M.; Huang, Dongqing; Lundeen, Rachel A.; Voytovich, Ulianna; Kennedy, Jacob J.; Ivey, Richard G.; Lin, Chenwei; Murillo, Oscar D.; Lorentzen, Travis D.; Colantonio, Simona; Caceres, Tessa W.; Roberts, Rhonda R.; Knotts, Joseph G.; Reading, Joshua J.; Perry, Candice D.; Richardson, Christopher W.; Garcia-Buntley, Sandra S.; Bocik, William; Hewitt, Stephen M.; Chowdhury, Shrabanti; Vandermeer, Jackie; Smith, Stephen D.; Gopal, Ajay K.; Ramchurren, Nirasha; Fling, Steven P.; Wang, Pei; Paulovich, Amanda G. 分享 收藏
Fanconi anemia-isogenic head and neck cancer cell line pairs: A basic and translational science resource Nguyen, Hiep Tai; Tang, Weiliang; Webster, Andrew L. H.; Whiteaker, Jeffrey R. R.; Chandler, Christopher M. M.; Errazquin, Ricardo; Roohollahi, Khashayar; Fritzke, Madeline; Hoskins, Elizabeth E. E.; Jonlin, Erica; Wakefield, Leslie; Sullivan, Lucas B. B.; Chen, Eleanor Y. Y.; Dorsman, Josephine; Brakenhoff, Ruud; Paulovich, Amanda G. G.; Grompe, Markus; Garcia-Escudero, Ramon; Wells, Susanne I. I.; Smogorzewska, Agata; Monnat Jr, Raymond J. J. 分享 收藏
Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety 脑室内B7-H3 CAR T细胞用于弥漫性内源性脑桥胶质瘤: 初步的人类首次生物活性和安全性 Vitanza, Nicholas A.; Wilson, Ashley L.; Huang, Wenjun; Seidel, Kristy; Brown, Christopher; Gustafson, Joshua A.; Yokoyama, Jason K.; Johnson, Adam J.; Baxter, Blake A.; Koning, Ryan W.; Reid, Aquene N.; Meechan, Michael; Biery, Matthew C.; Myers, Carrie; Rawlings-Rhea, Stephanie D.; Albert, Catherine M.; Browd, Samuel R.; Hauptman, Jason S.; Lee, Amy; Ojemann, Jeffrey G.; Berens, Michael E.; Dun, Matthew D.; Foster, Jessica B.; Crotty, Erin E.; Leary, Sarah E. S.; Cole, Bonnie L.; Perez, Francisco A.; Wright, Jason N.; Orentas, Rimas J.; Chour, Tony; Newell, Evan W.; Whiteaker, Jeffrey R.; Zhao, Lei; Paulovich, Amanda G.; Pinto, Navin; Gust, Juliane; Gardner, Rebecca A.; Jensen, Michael C.; Park, Julie R. 分享 收藏
Internal Standard Triggered-Parallel Reaction Monitoring Mass Spectrometry Enables Multiplexed Quantification of Candidate Biomarkers in Plasma Kennedy, Jacob J.; Whiteaker, Jeffrey R.; Ivey, Richard G.; Burian, Aura; Chowdhury, Shrabanti; Tsai, Chia-Feng; Liu, Tao; Lin, ChenWei; Murillo, Oscar D.; Lundeen, Rachel A.; Jones, Lisa A.; Gafken, Philip R.; Longton, Gary; Rodland, Karin D.; Skates, Steven J.; Landua, John; Wang, Pei; Lewis, Michael T.; Paulovich, Amanda G. 分享 收藏
Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer Huang, Dongqing; Chowdhury, Shrabanti; Wang, Hong; Savage, Sara R.; Ivey, Richard G.; Kennedy, Jacob J.; Whiteaker, Jeffrey R.; Lin, Chenwei; Hou, Xiaonan; Oberg, Ann L.; Larson, Melissa C.; Eskandari, Najmeh; Delisi, Davide A.; Gentile, Saverio; Huntoon, Catherine J.; Voytovich, Uliana J.; Shire, Zahra J.; Yu, Qing; Gygi, Steven P.; Hoofnagle, Andrew N.; Herbert, Zachary T.; Lorentzen, Travis D.; Calinawan, Anna; Karnitz, Larry M.; Weroha, S. John; Kaufmann, Scott H.; Zhang, Bing; Wang, Pei; Birrer, Michael J.; Paulovich, Amanda G. 分享 收藏
Targeted Mass Spectrometry Enables Multiplexed Quantification of Immunomodulatory Proteins in Clinical Biospecimens Whiteaker, Jeffrey R.; Lundeen, Rachel A.; Zhao, Lei; Schoenherr, Regine M.; Burian, Aura; Huang, Dongqing; Voytovich, Ulianna; Wang, Tao; Kennedy, Jacob J.; Ivey, Richard G.; Lin, Chenwei; Murillo, Oscar D.; Lorentzen, Travis D.; Thiagarajan, Mathangi; Colantonio, Simona; Caceres, Tessa W.; Roberts, Rhonda R.; Knotts, Joseph G.; Reading, Joshua J.; Kaczmarczyk, Jan A.; Richardson, Christopher W.; Garcia-Buntley, Sandra S.; Bocik, William; Hewitt, Stephen M.; Murray, Karen E.; Do, Nhan; Brophy, Mary; Wilz, Stephen W.; Yu, Hongbo; Ajjarapu, Samuel; Boja, Emily; Hiltke, Tara; Rodriguez, Henry; Paulovich, Amanda G. 分享 收藏
Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo function TCR和CAR信号的比较分析使CAR设计具有更高的抗原敏感性和体内功能 Salter, Alexander, I; Rajan, Anusha; Kennedy, Jacob J.; Ivey, Richard G.; Shelby, Sarah A.; Leung, Isabel; Templeton, Megan L.; Muhunthan, Vishaka; Voillet, Valentin; Sommermeyer, Daniel; Whiteaker, Jeffrey R.; Gottardo, Raphael; Veatch, Sarah L.; Paulovich, Amanda G.; Riddell, Stanley R. 分享 收藏
Targeted mass-spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP kinase, and AKT signaling Whiteaker, Jeffrey R.; Sharma, Kanika; Hoffman, Melissa A.; Kuhn, Eric; Zhao, Lei; Cocco, Alexandra R.; Schoenherr, Regine M.; Kennedy, Jacob J.; Voytovich, Ulianna; Lin, Chenwei; Fang, Bin; Bowers, Kiah; Whiteley, Gordon; Colantonio, Simona; Bocik, William; Roberts, Rhonda; Hiltke, Tara; Boja, Emily; Rodriguez, Henry; McCormick, Frank; Holderfield, Matthew; Carr, Steven A.; Koomen, John M.; Paulovich, Amanda G. 分享 收藏
Quantification of Human Epidermal Growth Factor Receptor 2 by Immunopeptide Enrichment and Targeted Mass Spectrometry in Formalin-Fixed Paraffin-Embedded and Frozen Breast Cancer Tissues Kennedy, Jacob J.; Whiteaker, Jeffrey R.; Kennedy, Laura C.; Bosch, Dustin E.; Lerch, Melissa L.; Schoenherr, Regine M.; Zhao, Lei; Lin, ChenWei; Chowdhury, Shrabanti; Kilgore, Mark R.; Allison, Kimberly H.; Wang, Pei; Hoofnagle, Andrew N.; Baird, Geoffrey Stuart; Paulovich, Amanda G. 分享 收藏
Loss of TGFβ signaling increases alternative end-joining DNA repair that sensitizes to genotoxic therapies across cancer types Tgf β 信号的缺失增加了替代性的末端连接DNA修复,从而对跨癌症类型的基因毒性疗法敏感 Liu, Qi; Palomero, Luis; Moore, Jade; Guix, Ines; Espin, Roderic; Aytes, Alvaro; Mao, Jian-Hua; Paulovich, Amanda G.; Whiteaker, Jeffrey R.; Ivey, Richard G.; Iliakis, George; Luo, Daxian; Chalmers, Anthony J.; Murnane, John; Pujana, Miquel Angel; Barcellos-Hoff, Mary Helen 分享 收藏
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Multiplexed Proteomic Analysis for Diagnosis and Screening of Five Primary Immunodeficiency Disorders From Dried Blood Spots Collins, Christopher J.; Yi, Fan; Dayuha, Remwilyn; Whiteaker, Jeffrey R.; Ochs, Hans D.; Freeman, Alexandra; Su, Helen C.; Paulovich, Amanda G.; Segundo, Gesmar R. S.; Torgerson, Troy; Hahn, Si Houn 分享 收藏
Rapid Multiplexed Proteomic Screening for Primary Immunodeficiency Disorders From Dried Blood Spots Collins, Christopher J.; Chang, Irene J.; Jung, Sunhee; Dayuha, Remwilyn; Whiteaker, Jeffrey R.; Segundo, Gesmar R. S.; Torgerson, Troy R.; Ochs, Hans D.; Paulovich, Amanda G.; Hahn, Si Houn 分享 收藏
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